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Search Results to Heide L Ford

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Ford, Heide

One or more keywords matched the following items that are connected to Ford, Heide

Item Type	Name
Academic Article	The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1.
Academic Article	Gene amplification is a mechanism of Six1 overexpression in breast cancer.
Academic Article	Cell cycle regulation of the human Six1 homeoprotein is mediated by APC(Cdh1).
Academic Article	The six family of homeobox genes in development and cancer.
Academic Article	The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
Academic Article	Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.
Academic Article	EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance.
Academic Article	Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.
Academic Article	Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome.
Academic Article	A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer.
Academic Article	Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.
Academic Article	Expression of Six1 homeobox gene during development of the mouse submandibular salivary gland.
Academic Article	Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.
Academic Article	Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation.
Academic Article	Biochemical and functional characterization of six SIX1 Branchio-oto-renal syndrome mutations.
Academic Article	Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.
Academic Article	SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer.
Academic Article	Specificity and prognostic validation of a polyclonal antibody to detect Six1 homeoprotein in ovarian cancer.
Concept	Homeodomain Proteins
Concept	Ribosomal Proteins
Concept	Membrane Transport Proteins
Concept	Proto-Oncogene Proteins c-myc
Concept	DNA-Binding Proteins
Concept	Oncogene Proteins, Fusion
Concept	Hedgehog Proteins
Concept	Green Fluorescent Proteins
Concept	Recombinant Fusion Proteins
Concept	Nuclear Proteins
Concept	Neoplasm Proteins
Concept	Mutant Proteins
Concept	Intracellular Signaling Peptides and Proteins
Concept	Proto-Oncogene Proteins c-mdm2
Concept	Anion Transport Proteins
Concept	Salivary Proteins and Peptides
Concept	Nerve Tissue Proteins
Concept	Repressor Proteins
Concept	Zebrafish Proteins
Academic Article	Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2.
Academic Article	CDK6 binds and promotes the degradation of the EYA2 protein.
Academic Article	MicroRNA-30a regulates zebrafish myogenesis through targeting the transcription factor Six1.
Academic Article	Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
Academic Article	Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
Academic Article	Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression.
Academic Article	The SIX1-EYA transcriptional complex as a therapeutic target in cancer.
Academic Article	TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.
Academic Article	The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.
Academic Article	CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.
Academic Article	Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.
Academic Article	A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance.
Grant	Identify inhibitors of the Six1/Eya interaction using high throughput screening
Grant	The anti-tumorigenic and anti-metastatic potential of Eya phosphatase inhibitors
Grant	Identify inhibitors of the Eya phosphatase activity using high throughput screeni
Academic Article	Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development.
Academic Article	The Eya phosphatase: Its unique role in cancer.
Grant	Role of Eya3 in regulating the immune microenvironment to promote breast tumor progression
Academic Article	Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression.
Academic Article	Eya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulation.
Academic Article	SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program.
Concept	Autophagy-Related Proteins
Concept	Serrate-Jagged Proteins
Academic Article	Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Academic Article	Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis.
Academic Article	VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk.
Academic Article	Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.
Academic Article	Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Academic Article	SIX1 reprograms myogenic transcription factors to maintain the rhabdomyosarcoma undifferentiated state.
Academic Article	Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis.
Academic Article	SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma.
Academic Article	EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.

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