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Search Results to Heide L Ford

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Ford, Heide

One or more keywords matched the following items that are connected to Ford, Heide

Item Type	Name
Academic Article	Gene amplification is a mechanism of Six1 overexpression in breast cancer.
Academic Article	Cell cycle regulation of the human Six1 homeoprotein is mediated by APC(Cdh1).
Academic Article	The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
Academic Article	Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.
Academic Article	TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitro.
Academic Article	Distinct TRAIL resistance mechanisms can be overcome by proteasome inhibition but not generally by synergizing agents.
Academic Article	EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance.
Academic Article	Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.
Academic Article	Biochemical and functional characterization of six SIX1 Branchio-oto-renal syndrome mutations.
Academic Article	Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.
Academic Article	The miR-106b-25 cluster targets Smad7, activates TGF-ß signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer.
Academic Article	SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer.
Academic Article	Specificity and prognostic validation of a polyclonal antibody to detect Six1 homeoprotein in ovarian cancer.
Concept	Cell Line, Tumor
Academic Article	Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2.
Academic Article	Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
Academic Article	Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3.
Academic Article	TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.
Academic Article	The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.
Academic Article	CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.
Academic Article	Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.
Academic Article	A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance.
Academic Article	Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-ß signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
Academic Article	EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells.
Academic Article	Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression.
Academic Article	The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L.
Academic Article	Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Academic Article	VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk.
Academic Article	Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.
Academic Article	SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma.
Academic Article	EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression.
Academic Article	Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma.
Academic Article	Remembering Hypoxia: Uncovering the Long-Term Effects of Transient Oxygen Deprivation on IFN Signaling and Progression of Breast Cancer.
Academic Article	Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor-Initiating Cells Characterized by IFN/STAT1 Activity.
Academic Article	EYA3 regulation of NF-?B and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis.
Academic Article	Transcriptional differences between normal and glioma-derived glial progenitor cells identify a core set of dysregulated genes.
Academic Article	MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity.
Academic Article	Cryo-EM structures reveal the PP2A-B55a and Eya3 interaction that can be disrupted by a peptide inhibitor.
Academic Article	Rational Design of Novel Allosteric EYA2 Inhibitors as Potential Therapeutics for Multiple Brain Cancers.

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