Connection

Contact Us
If you have any questions or feedback please contact us.

Search Results to Kathryn Horwitz

This is a "connection" page, showing the details of why an item matched the keywords from your search.

Search Results

Horwitz, Kathryn

One or more keywords matched the following items that are connected to Horwitz, Kathryn

Item Type	Name
Academic Article	Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen.
Academic Article	The role of progestins and progesterone receptors in the treatment of breast cancer.
Academic Article	Progesterone receptor replenishment in T47D human breast cancer cells. Roles of protein synthesis and hormone metabolism.
Academic Article	In situ photolinked nuclear progesterone receptors of human breast cancer cells: subunit molecular weights after transformation and translocation.
Academic Article	Progesterone receptors in human breast cancer. Stoichiometric translocation and nuclear receptor processing.
Academic Article	Is a functional estrogen receptor always required for progesterone receptor induction in breast cancer?
Academic Article	Nuclear estrogen receptor release from antiestrogen suppression: amplified induction of progesterone receptor in MCF-7 human breast cancer cells.
Academic Article	Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.
Academic Article	Novel mechanisms of antiprogestin action.
Academic Article	The leucine zippers of c-fos and c-jun for progesterone receptor dimerization: A-dominance in the A/B heterodimer.
Academic Article	A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.
Academic Article	Progestin action and progesterone receptor structure in human breast cancer: a review.
Academic Article	Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.
Academic Article	Hormone-dependent covalent modification and processing of human progesterone receptors in the nucleus.
Academic Article	Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP.
Academic Article	Can hormone "resistant" breast cancer cells be inappropriately stimulated by tamoxifen?
Academic Article	Role of phosphorylation on DNA binding and transcriptional functions of human progesterone receptors.
Academic Article	Canine vascular tissues are targets for androgens, estrogens, progestins, and glucocorticoids.
Academic Article	The subunit structure of human breast cancer progesterone receptors: characterization by chromatography and photoaffinity labeling.
Academic Article	Selecting endocrine therapy in breast cancer.
Academic Article	Studies on mechanisms of estrogen and antiestrogen action in human breast cancer.
Academic Article	DNA bending is induced by binding of the glucocorticoid receptor DNA binding domain and progesterone receptors to their response element.
Academic Article	Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity.
Academic Article	Selective down-regulation of progesterone receptor isoform B in poorly differentiated human endometrial cancer cells: implications for unopposed estrogen action.
Academic Article	Differential expression of the A and B isoforms of progesterone receptor in human endometrial cancer cells. Only progesterone receptor B is induced by estrogen and associated with strong transcriptional activation.
Academic Article	An N-terminal inhibitory function, IF, suppresses transcription by the A-isoform but not the B-isoform of human progesterone receptors.
Academic Article	Specific progesterone receptors in human breast cancer.
Academic Article	Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.
Academic Article	Progesterone receptor variants found in breast cells repress transcription by wild-type receptors.
Academic Article	Hormone-resistant breast cancer or "feeding the hand that bites you".
Academic Article	Variant estrogen and progesterone receptor messages in human vascular smooth muscle.
Academic Article	Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways.
Academic Article	Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals.
Academic Article	The N-terminal region of the human progesterone A-receptor. Structural analysis and the influence of the DNA binding domain.
Academic Article	Surprises with antiprogestins: novel mechanisms of progesterone receptor action.
Academic Article	The molecular biology of RU486. Is there a role for antiprogestins in the treatment of breast cancer?
Academic Article	Novel mechanisms of antiprogestin action.
Academic Article	The N-terminal region of human progesterone B-receptors: biophysical and biochemical comparison to A-receptors.
Academic Article	Mapping the unique activation function 3 in the progesterone B-receptor upstream segment. Two LXXLL motifs and a tryptophan residue are required for activity.
Academic Article	Cellular heterogeneity and mutant oestrogen receptors in hormone resistant breast cancer.
Academic Article	Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells.
Academic Article	New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation.
Academic Article	Epitope mapping of the anti-human progesterone receptor monoclonal antibody, AB-52.
Academic Article	The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression.
Academic Article	The antiprogestin RU38 486: receptor-mediated progestin versus antiprogestin actions screened in estrogen-insensitive T47Dco human breast cancer cells.
Academic Article	A physiological role for estrogen and progesterone in breast cancer.
Academic Article	Progesterone receptors A and B differentially affect the growth of estrogen-dependent human breast tumor xenografts.
Academic Article	Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure.
Academic Article	Breast cancer patients with progesterone receptor PR-A-rich tumors have poorer disease-free survival rates.
Academic Article	Insights into the role of progesterone receptors in breast cancer.
Academic Article	5'-Heterogeneity in human progesterone receptor transcripts predicts a new amino-terminal truncated "C"-receptor and unique A-receptor messages.
Academic Article	Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes.
Academic Article	Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B.
Academic Article	Current status of estrogen and progesterone receptors in breast cancer.
Academic Article	Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone.
Academic Article	Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts.
Academic Article	Progesterone receptor action: translating studies in breast cancer models to clinical insights.
Academic Article	Progesterone and progesterone receptors in experimental breast cancer.
Academic Article	Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation.
Academic Article	Human progesterone receptors: synthesis, structure, and phosphorylation.
Academic Article	T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.
Academic Article	ALU repeats in promoters are position-dependent co-response elements (coRE) that enhance or repress transcription by dimeric and monomeric progesterone receptors.
Academic Article	Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: analysis with zinc finger mutants and the progesterone antagonist ZK98299.
Academic Article	Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers.
Academic Article	Association of the Ku autoantigen/DNA-dependent protein kinase holoenzyme and poly(ADP-ribose) polymerase with the DNA binding domain of progesterone receptors.
Academic Article	Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring?
Academic Article	Phosphotryptic peptide analysis of human progesterone receptor. New phosphorylated sites formed in nuclei after hormone treatment.
Academic Article	Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch.
Academic Article	Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: characterization of an assay in breast cancer cell lines.
Academic Article	Estrogen control of progesterone receptor induction in human breast cancer: role of nuclear estrogen receptor.
Academic Article	Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation.
Academic Article	Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometry.
Academic Article	Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone.
Academic Article	The central role of progesterone receptors and progestational agents in the management and treatment of breast cancer.
Academic Article	The structure and function of progesterone receptors in breast cancer.
Academic Article	Steroid receptor analyses of nine human breast cancer cell lines.
Academic Article	Progesterone metabolism in T47Dco human breast cancer cells--II. Intracellular metabolic path of progesterone and synthetic progestins.
Academic Article	Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies.
Academic Article	Immunologic analysis of human breast cancer progesterone receptors. 2. Structure, phosphorylation, and processing.
Academic Article	Structural analyses of progesterone receptors.
Academic Article	Progesterone metabolism in T47Dco human breast cancer cells--I. 5 alpha-pregnan-3 beta,6 alpha-diol-20-one is the secreted product.
Academic Article	The structure of progesterone receptors.
Academic Article	Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.
Academic Article	Estrogen-insensitive progesterone receptors in a human breast cancer cell line: characterization of receptors and of a ligand exchange assay.
Academic Article	Expression profiling of human breast cancers and gene regulation by progesterone receptors.
Academic Article	New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.
Academic Article	How do breast cancers become hormone resistant?
Academic Article	Mechanisms of hormone resistance in breast cancer.
Academic Article	The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT.
Academic Article	Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology.
Academic Article	Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1).
Academic Article	Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity.
Academic Article	Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast cancer cells.
Academic Article	Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75.
Academic Article	Predicting response to endocrine therapy in human breast cancer: a hypothesis.
Academic Article	Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth.
Academic Article	MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors.
Academic Article	Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome.
Academic Article	Progestin-dependent induction of vascular endothelial growth factor in human breast cancer cells: preferential regulation by progesterone receptor B.
Academic Article	Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1.
Academic Article	The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells.
Academic Article	GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway.
Academic Article	Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis.
Academic Article	Progesterone receptor phosphorylation complexities in defining a functional role.
Academic Article	Transient expression of human and chicken progesterone receptors does not support alternative translational initiation from a single mRNA as the mechanism generating two receptor isoforms.
Academic Article	Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis.
Academic Article	Androgen receptor assay with [3H]methyltrienolone (R1881) in the presence of progesterone receptors.
Academic Article	Unliganded progesterone receptors attenuate taxane-induced breast cancer cell death by modulating the spindle assembly checkpoint.
Academic Article	Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: analysis of breast cancer cell mixtures and genetic instability of the T47D line.
Academic Article	Human progesterone A-receptors can be synthesized intracellularly and are biologically functional.
Academic Article	Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptor.
Academic Article	Multiple human progesterone receptor messenger ribonucleic acids and their autoregulation by progestin agonists and antagonists in breast cancer cells.
Academic Article	Receptors and breast cancer: do we know it all?
Academic Article	Growth inhibition and increase of insulin receptors in antiestrogen-resistant T47DCO human breast cancer cells by progestins: implications for endocrine therapies.
Academic Article	Progesterone receptor determination in human breast tumors by immunocytochemical and biochemical techniques.
Academic Article	Progesterone receptors, their isoforms and progesterone regulated transcription.
Academic Article	Synthesis of human progesterone receptors in T47D cells. Nascent A- and B-receptors are active without a phosphorylation-dependent post-translational maturation step.
Academic Article	Human progesterone receptor transformation and nuclear down-regulation are independent of phosphorylation.
Academic Article	Purification, monoclonal antibody production and structural analyses of human progesterone receptors.
Concept	Receptors, Progesterone
Concept	Progesterone Congeners
Concept	Progesterone
Academic Article	Post-translational modifications of the progesterone receptors.
Academic Article	Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease.
Academic Article	Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells.
Grant	TISSUE-SPECIFIC EFFECTS OF PROGESTINS
Grant	PHOSPHORYLATION OF BREAST CANCER PROGESTERONE RECEPTORS
Grant	Mechanisms of Progesterone Receptor Action
Grant	PROGESTERONE RECEPTORS IN BREAST CANCER
Academic Article	SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner.
Academic Article	90 YEARS OF PROGESTERONE: Progesterone and progesterone receptors in breast cancer: past, present, future.
Academic Article	Response to: Progesterone and breast cancer pathogenesis.

Search Criteria

Progesterone