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Search Results to Kathryn Horwitz

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One or more keywords matched the following items that are connected to Horwitz, Kathryn

Item TypeName
Academic Article Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen.
Academic Article The role of progestins and progesterone receptors in the treatment of breast cancer.
Academic Article Progesterone receptor replenishment in T47D human breast cancer cells. Roles of protein synthesis and hormone metabolism.
Academic Article In situ photolinked nuclear progesterone receptors of human breast cancer cells: subunit molecular weights after transformation and translocation.
Academic Article Progesterone receptors in human breast cancer. Stoichiometric translocation and nuclear receptor processing.
Academic Article Is a functional estrogen receptor always required for progesterone receptor induction in breast cancer?
Academic Article Nuclear estrogen receptor release from antiestrogen suppression: amplified induction of progesterone receptor in MCF-7 human breast cancer cells.
Academic Article Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.
Academic Article Hormone 'resistance' in breast cancer: the role of normal and mutant steroid receptors.
Academic Article Progestin action and progesterone receptor structure in human breast cancer: a review.
Academic Article Hormone-dependent covalent modification and processing of human progesterone receptors in the nucleus.
Academic Article Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP.
Academic Article Can hormone "resistant" breast cancer cells be inappropriately stimulated by tamoxifen?
Academic Article The subunit structure of human breast cancer progesterone receptors: characterization by chromatography and photoaffinity labeling.
Academic Article Selecting endocrine therapy in breast cancer.
Academic Article Studies on mechanisms of estrogen and antiestrogen action in human breast cancer.
Academic Article Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity.
Academic Article Specific progesterone receptors in human breast cancer.
Academic Article Progesterone receptor variants found in breast cells repress transcription by wild-type receptors.
Academic Article Hormone-resistant breast cancer or "feeding the hand that bites you".
Academic Article Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways.
Academic Article Functional analysis of a mutant estrogen receptor isolated from T47Dco breast cancer cells.
Academic Article Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals.
Academic Article The mouse mammary tumor virus promoter adopts distinct chromatin structures in human breast cancer cells with and without glucocorticoid receptor.
Academic Article Human breast cancer: biologically active estrogen receptor in the absence of estrogen?
Academic Article Surprises with antiprogestins: novel mechanisms of progesterone receptor action.
Academic Article The molecular biology of RU486. Is there a role for antiprogestins in the treatment of breast cancer?
Academic Article Novel mechanisms of antiprogestin action.
Academic Article Nuclear receptor conformation, coregulators, and tamoxifen-resistant breast cancer.
Academic Article Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells.
Academic Article Cellular heterogeneity and mutant oestrogen receptors in hormone resistant breast cancer.
Academic Article Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells.
Academic Article New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation.
Academic Article The antiprogestin RU38 486: receptor-mediated progestin versus antiprogestin actions screened in estrogen-insensitive T47Dco human breast cancer cells.
Academic Article A physiological role for estrogen and progesterone in breast cancer.
Academic Article Progesterone receptors A and B differentially affect the growth of estrogen-dependent human breast tumor xenografts.
Academic Article Breast cancer patients with progesterone receptor PR-A-rich tumors have poorer disease-free survival rates.
Academic Article Insights into the role of progesterone receptors in breast cancer.
Academic Article Estradiol regulates different genes in human breast tumor xenografts compared with the identical cells in culture.
Academic Article 5'-Heterogeneity in human progesterone receptor transcripts predicts a new amino-terminal truncated "C"-receptor and unique A-receptor messages.
Academic Article Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes.
Academic Article Current status of estrogen and progesterone receptors in breast cancer.
Academic Article Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.
Academic Article Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts.
Academic Article Progesterone receptor action: translating studies in breast cancer models to clinical insights.
Academic Article Progestins in hormone replacement therapies reactivate cancer stem cells in women with preexisting breast cancers: a hypothesis.
Academic Article The Year in Basic Science: update of estrogen plus progestin therapy for menopausal hormone replacement implicating stem cells in the increased breast cancer risk.
Academic Article Progesterone and progesterone receptors in experimental breast cancer.
Academic Article T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.
Academic Article The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
Academic Article Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer.
Academic Article Tamoxifen resistant breast cancer: coregulators determine the direction of transcription by antagonist-occupied steroid receptors.
Academic Article Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers.
Academic Article Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring?
Academic Article Prolactin and estrogen receptors in breast cancer.
Academic Article Bringing estrogen receptors under control.
Academic Article Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch.
Academic Article Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: characterization of an assay in breast cancer cell lines.
Academic Article Estrogen control of progesterone receptor induction in human breast cancer: role of nuclear estrogen receptor.
Academic Article Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation.
Academic Article Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometry.
Academic Article An immunohistochemical method to study breast cancer cell subpopulations and their growth regulation by hormones in three-dimensional cultures.
Academic Article Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone.
Academic Article Phytoestrogen interaction with estrogen receptors in human breast cancer cells.
Academic Article The central role of progesterone receptors and progestational agents in the management and treatment of breast cancer.
Academic Article The structure and function of progesterone receptors in breast cancer.
Academic Article Steroid receptor analyses of nine human breast cancer cell lines.
Academic Article Progesterone metabolism in T47Dco human breast cancer cells--II. Intracellular metabolic path of progesterone and synthetic progestins.
Academic Article Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies.
Academic Article Immunologic analysis of human breast cancer progesterone receptors. 2. Structure, phosphorylation, and processing.
Academic Article Progesterone metabolism in T47Dco human breast cancer cells--I. 5 alpha-pregnan-3 beta,6 alpha-diol-20-one is the secreted product.
Academic Article The structure of progesterone receptors.
Academic Article Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.
Academic Article Nuclear estrogen receptors. Effect of inhibitors on processing and steady state levels.
Academic Article Estrogen-insensitive progesterone receptors in a human breast cancer cell line: characterization of receptors and of a ligand exchange assay.
Academic Article Subcellular compartmentalization of estrogen receptors in human breast cancer cells.
Academic Article When tamoxifen turns bad.
Academic Article Expression profiling of human breast cancers and gene regulation by progesterone receptors.
Academic Article New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.
Academic Article How do breast cancers become hormone resistant?
Academic Article Mechanisms of hormone resistance in breast cancer.
Academic Article Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology.
Academic Article Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1).
Academic Article Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity.
Academic Article Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast cancer cells.
Academic Article Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75.
Academic Article Predicting response to endocrine therapy in human breast cancer: a hypothesis.
Academic Article Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth.
Academic Article MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors.
Academic Article Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome.
Academic Article Estrogens and progestins in mammary development and neoplasia. Introduction.
Academic Article Progestin-dependent induction of vascular endothelial growth factor in human breast cancer cells: preferential regulation by progesterone receptor B.
Academic Article Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1.
Academic Article The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells.
Academic Article Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph node metastases.
Academic Article Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis.
Academic Article Molecular signatures of neoadjuvant endocrine therapy for breast cancer: characteristics of response or intrinsic resistance.
Academic Article Estrogen regulated gene expression in response to neoadjuvant endocrine therapy of breast cancers: tamoxifen agonist effects dominate in the presence of an aromatase inhibitor.
Academic Article Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium.
Academic Article Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis.
Academic Article Androgen receptor assay with [3H]methyltrienolone (R1881) in the presence of progesterone receptors.
Academic Article Unliganded progesterone receptors attenuate taxane-induced breast cancer cell death by modulating the spindle assembly checkpoint.
Academic Article Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: analysis of breast cancer cell mixtures and genetic instability of the T47D line.
Academic Article Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptor.
Academic Article Multiple human progesterone receptor messenger ribonucleic acids and their autoregulation by progestin agonists and antagonists in breast cancer cells.
Academic Article Actinomycin D prevents nuclear processing of estrogen receptor.
Academic Article Receptors and breast cancer: do we know it all?
Academic Article Growth inhibition and increase of insulin receptors in antiestrogen-resistant T47DCO human breast cancer cells by progestins: implications for endocrine therapies.
Academic Article Progesterone receptor determination in human breast tumors by immunocytochemical and biochemical techniques.
Academic Article Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features.
Academic Article ER, PR, HER2, Ki-67 and CK5 in Early and Late Relapsing Breast Cancer-Reduced CK5 Expression in Metastases.
Academic Article Human progesterone receptor transformation and nuclear down-regulation are independent of phosphorylation.
Concept Breast Neoplasms
Academic Article Post-translational modifications of the progesterone receptors.
Academic Article Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling.
Academic Article Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease.
Academic Article Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells.
Academic Article Role of epigenetic modifications in luminal breast cancer.
Grant PHOSPHORYLATION OF BREAST CANCER PROGESTERONE RECEPTORS
Grant Mechanisms of Progesterone Receptor Action
Grant PROGESTERONE RECEPTORS IN BREAST CANCER
Grant NUCLEAR ESTROGEN RECEPTORS IN BREAST CANCER
Academic Article Fibroblast subtypes define a metastatic matrisome in breast cancer.
Academic Article 90 YEARS OF PROGESTERONE: Progesterone and progesterone receptors in breast cancer: past, present, future.
Academic Article Response to: Progesterone and breast cancer pathogenesis.

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