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Search Results to Kurt R Stenmark

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Item TypeName
Academic Article Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.
Academic Article Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.
Academic Article Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media.
Academic Article Persistent pulmonary hypertension of the newborn.
Academic Article Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension.
Academic Article Diethylcarbamazine inhibits acute and chronic hypoxic pulmonary hypertension in awake rats.
Academic Article Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension.
Academic Article Progressive loss of vasodilator responsive component of pulmonary hypertension in neonatal calves exposed to 4,570 m.
Academic Article Alterations in extracellular matrix protein expression in neonatal pulmonary hypertension: implications for vascular function.
Academic Article Leukotriene C4 and D4 in neonates with hypoxemia and pulmonary hypertension.
Academic Article Right ventricular angiotensin converting enzyme activity and expression is increased during hypoxic pulmonary hypertension.
Academic Article Role of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension.
Academic Article Smooth muscle cell heterogeneity: role of specific smooth muscle cell subpopulations in pulmonary vascular disease.
Academic Article Treatments for severe pulmonary hypertension.
Academic Article Mechanisms of structural remodeling in chronic pulmonary hypertension.
Academic Article Hypoxia induces cell-specific changes in gene expression in vascular wall cells: implications for pulmonary hypertension.
Academic Article Transforming growth factor-beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries.
Academic Article Myocyte cytoskeletal disorganization and right heart failure in hypoxia-induced neonatal pulmonary hypertension.
Academic Article Unilateral pulmonary hypertension as a result of chronic high flow to one lung.
Academic Article Bromodeoxyuridine labeling and DNA content of pulmonary arterial medial cells from hypoxia-exposed and nonexposed healthy calves.
Academic Article Hypoxia-induced pulmonary artery adventitial remodeling and neovascularization: contribution of progenitor cells.
Academic Article Lung endothelial cell proliferation in normal and pulmonary hypertensive neonatal calves.
Academic Article Cellular adaptation during chronic neonatal hypoxic pulmonary hypertension.
Academic Article Hypoxia, leukocytes, and the pulmonary circulation.
Academic Article Neonatal calves develop airflow limitation due to chronic hypobaric hypoxia.
Academic Article Changes in lung eicosanoid content during normal and abnormal transition in perinatal lambs.
Academic Article Determination of transforming growth factor-beta mRNA levels in pulmonary arteries from normal and hypoxic calves.
Academic Article Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage.
Academic Article Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.
Academic Article Role of reactive oxygen species in chronic hypoxia-induced pulmonary hypertension and vascular remodeling.
Academic Article Evidence for cell fusion is absent in vascular lesions associated with pulmonary arterial hypertension.
Academic Article Inflammation, growth factors, and pulmonary vascular remodeling.
Academic Article Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment.
Academic Article Cellular and molecular basis of pulmonary arterial hypertension.
Academic Article Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.
Academic Article Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall.
Academic Article Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension.
Academic Article Lung extracellular superoxide dismutase overexpression lessens bleomycin-induced pulmonary hypertension and vascular remodeling.
Academic Article Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension.
Academic Article Cell-based therapies in pulmonary hypertension: who, what, and when?
Academic Article Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension.
Academic Article Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells.
Academic Article Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.
Academic Article Circulating myeloid-derived suppressor cells are increased and activated in pulmonary hypertension.
Academic Article Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures.
Academic Article Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Academic Article Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia.
Academic Article Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change.
Academic Article Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGF? receptor-JNK1 signalling.
Academic Article MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension.
Academic Article The renin-angiotensin system in pulmonary hypertension.
Academic Article Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension.
Academic Article Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function.
Academic Article Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension.
Academic Article Abnormal alveolar cells in monocrotaline induced pulmonary hypertension.
Academic Article Cellular and molecular pathobiology of pulmonary arterial hypertension.
Academic Article Eicosanoids decrease with successful extracorporeal membrane oxygenation therapy in neonatal pulmonary hypertension.
Academic Article Alteration of the pulsatile load in the high-altitude calf model of pulmonary hypertension.
Academic Article Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase c isozymes.
Academic Article New hope for the treatment of pulmonary hypertension: novel approaches to a complex disease.
Academic Article Pulmonary vascular impedance and wave reflections in the hypoxic calf.
Academic Article Insulin-like growth factor I and pulmonary hypertension induced by continuous air embolization in sheep.
Academic Article Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension.
Academic Article Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal?
Academic Article Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms.
Academic Article Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors.
Academic Article In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation.
Academic Article Emerging therapies for the treatment of pulmonary hypertension.
Academic Article Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.
Academic Article Fibrocytes: potential new therapeutic targets for pulmonary hypertension?
Academic Article Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization.
Academic Article Linked opening angle and histological and mechanical aspects of the proximal pulmonary arteries of healthy and pulmonary hypertensive rats and calves.
Academic Article Plasma proteomics of differential outcome to long-term therapy in children with idiopathic pulmonary arterial hypertension.
Academic Article Response of lobar vessels to hypoxic pulmonary hypertension.
Academic Article Response to letter regarding article, ?histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid?.
Academic Article Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m.
Academic Article Physiologic and molecular consequences of endothelial Bmpr2 mutation.
Academic Article Circulating fibrocytes are increased in children and young adults with pulmonary hypertension.
Academic Article Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.
Academic Article Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.
Academic Article Activation of the unfolded protein response is associated with pulmonary hypertension.
Academic Article Mechanics and mechanisms of pulmonary hypertension: An introduction to the 55(th) annual Thomas L. Petty Aspen Lung Conference.
Academic Article Clinical trials in neonates and children: Report of the pulmonary hypertension academic research consortium pediatric advisory committee.
Academic Article Vascular remodeling in neonatal pulmonary hypertension. Role of the smooth muscle cell.
Academic Article [Inhibition of hypoxic pulmonary vasoconstriction by leukotriene blockade].
Concept Hypertension, Pulmonary
Academic Article Bronchus-associated lymphoid tissue in pulmonary hypertension produces pathologic autoantibodies.
Academic Article Functional classification of pulmonary hypertension in children: Report from the PVRI pediatric taskforce, Panama 2011.
Academic Article MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
Academic Article Relevant issues in the pathology and pathobiology of pulmonary hypertension.
Academic Article An official American Thoracic Society Statement: pulmonary hypertension phenotypes.
Academic Article High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization.
Academic Article Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
Academic Article Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.
Academic Article Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-?B pathway.
Academic Article Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension.
Academic Article Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction.
Academic Article Chemotherapy-induced pulmonary hypertension: role of alkylating agents.
Academic Article Vascular stiffening in pulmonary hypertension: cause or consequence? (2013 Grover Conference series).
Academic Article [Relevant issues in the pathology and pathobiology of pulmonary hypertension].
Academic Article The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.
Academic Article Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration.
Academic Article Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.
Academic Article Emerging roles for histone deacetylases in pulmonary hypertension and right ventricular remodeling (2013 Grover Conference series).
Academic Article The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
Academic Article MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension.
Academic Article The altitude at which a calf is born and raised influences the rate at which mean pulmonary arterial pressure increases with age.
Academic Article Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension.
Academic Article Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society.
Academic Article Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension.
Academic Article Pulmonary Arterial Stiffness: Toward a New Paradigm in Pulmonary Arterial Hypertension Pathophysiology and Assessment.
Academic Article Right Ventricular Longitudinal Strain Is Depressed in a Bovine Model of Pulmonary Hypertension.
Academic Article Stiffening of the Extrapulmonary Arteries From Rats in Chronic Hypoxic Pulmonary Hypertension.
Academic Article Endothelial-to-Mesenchymal Transition: An Evolving Paradigm and a Promising Therapeutic Target in PAH.
Academic Article Pulmonary Veno-occlusive Disease and Pulmonary Hypertension in Dogs: Striking Similarities to the Human Condition.
Academic Article Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
Academic Article Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension.
Academic Article Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.
Academic Article Superoxide Dismutase 3 R213G Single-Nucleotide Polymorphism Blocks Murine Bleomycin-Induced Fibrosis and Promotes Resolution of Inflammation.
Academic Article Transcription factors, transcriptional coregulators, and epigenetic modulation in the control of pulmonary vascular cell phenotype: therapeutic implications for pulmonary hypertension (2015 Grover Conference series).
Academic Article Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation.
Academic Article Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency.
Academic Article Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH).
Grant Fibroblasts and Mononuclear Fibrogenic Cells Drive Right Ventricular Pulmonary Ar
Grant Lung Vascular Disease in Infants and Children: Mechanisms and Treatment
Grant Crosstalk Between Metabolism and Inflammation in Pulmonary Hypertension
Grant Adaptation to Hypoxia
Grant LUNG LIPIDS IN NEONATAL PULMONARY HYPERTENSIVE DISEASES
Academic Article A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.
Academic Article TGF-? activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
Academic Article Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming.
Academic Article Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
Academic Article Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.
Academic Article Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension.
Academic Article Helicity and Vorticity of Pulmonary Arterial Flow in Patients With Pulmonary Hypertension: Quantitative Analysis of Flow Formations.
Academic Article Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension.
Academic Article A Twist on Pulmonary Vascular Remodeling: Endothelial to Mesenchymal Transition?
Academic Article How Many FOXs Are There on The Road to Pulmonary Hypertension?
Academic Article Peroxisome Proliferator-activated Receptor ? and Mitochondria: Drivers or Passengers on the Road to Pulmonary Hypertension?
Academic Article JNK2 regulates vascular remodeling in pulmonary hypertension.
Academic Article Repurposing rosiglitazone, a PPAR-? agonist and oral antidiabetic, as an inhaled formulation, for the treatment of PAH.
Academic Article Proximal pulmonary vascular stiffness as a prognostic factor in children with pulmonary arterial hypertension.
Academic Article Urocortin 2: will a drug targeting both the vasculature and the right ventricle be the future of pulmonary hypertension therapy?
Academic Article Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension.
Academic Article Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension.
Academic Article Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention.
Academic Article Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease.
Academic Article Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling.
Academic Article Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives.
Academic Article Pre-clinical assessment of a water-in-fluorocarbon emulsion for the treatment of pulmonary vascular diseases.
Academic Article Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature.
Concept Familial Primary Pulmonary Hypertension
Academic Article CAR, a Homing Peptide, Prolongs Pulmonary Preferential Vasodilation by Increasing Pulmonary Retention and Reducing Systemic Absorption of Liposomal Fasudil.
Academic Article The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation.
Academic Article A current view of G protein-coupled receptor - mediated signaling in pulmonary hypertension: finding opportunities for therapeutic intervention.
Academic Article An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease.
Academic Article Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.
Academic Article Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
Academic Article Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension.
Academic Article A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.
Academic Article Targeting histone acetylation in pulmonary hypertension and right ventricular hypertrophy.
Academic Article Pluripotent hematopoietic stem cells augment a-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension.
Academic Article Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.
Academic Article c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells.
Academic Article Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Academic Article Publisher Correction: Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.
Academic Article Perspective: pathobiological paradigms in pulmonary hypertension, time for reappraisal.
Academic Article RNA-Binding Proteins in Pulmonary Hypertension.
Academic Article Inflammation, immunity, and vascular remodeling in pulmonary hypertension; Evidence for complement involvement?
Academic Article Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application.
Academic Article 17?-Estradiol and estrogen receptor a protect right ventricular function in pulmonary hypertension via BMPR2 and apelin.
Academic Article Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension.
Academic Article Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.
Academic Article Mechanisms Contributing to the Dysregulation of miRNA-124 in Pulmonary Hypertension.
Academic Article Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study.
Academic Article Endothelial cell PHD2-HIF1a-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension.
Academic Article The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension.
Academic Article Complement-containing small extracellular vesicles from adventitial fibroblasts induce proinflammatory and metabolic reprogramming in macrophages.
Academic Article Brief Report: Case Comparison of Therapy With the Histone Deacetylase Inhibitor Vorinostat in a Neonatal Calf Model of Pulmonary Hypertension.
Academic Article Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective.
Academic Article Peripheral Blood Inflammation Profile of Patients with Pulmonary Arterial Hypertension Using the High-Throughput Olink Proteomics Platform.
Academic Article Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia.
Academic Article The role of macrophages in right ventricular remodeling in experimental pulmonary hypertension.
Academic Article Tensions in Taxonomies: Current Understanding and Future Directions in the Pathobiologic Basis and Treatment of Group 1 and Group 3 Pulmonary Hypertension.
Academic Article Histone deacetylase inhibitors synergize with sildenafil to suppress purine metabolism and proliferation in pulmonary hypertension.
Academic Article The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension.
Academic Article Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model.
Academic Article Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension.
Academic Article Characterizing the Spatiotemporal Transcriptomic Response of the Right Ventricle to Acute Pressure Overload.
Academic Article SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension.
Academic Article Microenvironmental regulation of T-cells in pulmonary hypertension.

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