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Search Results to Kurt R Stenmark

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Stenmark, Kurt

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Item Type	Name
Academic Article	Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media.
Academic Article	Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo.
Academic Article	Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension.
Academic Article	Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension.
Academic Article	Progressive loss of vasodilator responsive component of pulmonary hypertension in neonatal calves exposed to 4,570 m.
Academic Article	Functional and structural adaptation of the yak pulmonary circulation to residence at high altitude.
Academic Article	Expression and localization of tropoelastin mRNA in the developing bovine pulmonary artery is dependent on vascular cell phenotype.
Academic Article	Hypoxia increases bromodeoxyuridine labeling indices in bovine neonatal pulmonary arteries.
Academic Article	Selected isozymes of PKC contribute to augmented growth of fetal and neonatal bovine PA adventitial fibroblasts.
Academic Article	Smooth muscle cell heterogeneity in pulmonary and systemic vessels. Importance in vascular disease.
Academic Article	Enhanced growth of fetal and neonatal pulmonary artery adventitial fibroblasts is dependent on protein kinase C.
Academic Article	Hypoxia stimulates proliferation of a unique cell population isolated from the bovine vascular media.
Academic Article	The Ca2+-dependent isozymes of protein kinase C are uniquely important in the enhanced growth of immature adventitial fibroblasts isolated from the bovine pulmonary arterial wall at a time of heightened susceptibility to vascular injury.
Academic Article	Smooth muscle cells isolated from discrete compartments of the mature vascular media exhibit unique phenotypes and distinct growth capabilities.
Academic Article	Hypoxic growth of bovine pulmonary artery smooth muscle cells: dependence on synergy, heterogeneity, and injury-induced phenotypic change.
Academic Article	Mechanisms regulating cAMP-mediated growth of bovine neonatal pulmonary artery smooth muscle cells.
Academic Article	Transforming growth factor-beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries.
Academic Article	Myocyte cytoskeletal disorganization and right heart failure in hypoxia-induced neonatal pulmonary hypertension.
Academic Article	Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases.
Academic Article	Pulmonary artery smooth muscle cells from chronically hypoxic neonatal calves retain fetal-like and acquire new growth properties.
Academic Article	Hypoxia-induced inhibition of tropoelastin synthesis by neonatal calf pulmonary artery smooth muscle cells.
Academic Article	Bromodeoxyuridine labeling and DNA content of pulmonary arterial medial cells from hypoxia-exposed and nonexposed healthy calves.
Academic Article	Hypoxia-induced pulmonary artery adventitial remodeling and neovascularization: contribution of progenitor cells.
Academic Article	Hypoxic activation of adventitial fibroblasts: role in vascular remodeling.
Academic Article	Lung endothelial cell proliferation in normal and pulmonary hypertensive neonatal calves.
Academic Article	Bovine distal pulmonary arterial media is composed of a uniform population of well-differentiated smooth muscle cells with low proliferative capabilities.
Academic Article	Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts.
Academic Article	Neonatal calves develop airflow limitation due to chronic hypobaric hypoxia.
Academic Article	Determination of transforming growth factor-beta mRNA levels in pulmonary arteries from normal and hypoxic calves.
Academic Article	Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression.
Academic Article	Hypoxia-induced alterations in protein kinase C zeta signaling result in augmented fibroblast proliferation.
Academic Article	Circulating mononuclear cells with a dual, macrophage-fibroblast phenotype contribute robustly to hypoxia-induced pulmonary adventitial remodeling.
Academic Article	Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage.
Academic Article	Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: a process mediated by hypoxia and endothelin-1.
Academic Article	Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cells.
Academic Article	Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall.
Academic Article	Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension.
Academic Article	Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension.
Academic Article	Subendothelial cells from normal bovine arteries exhibit autonomous growth and constitutively activated intracellular signaling.
Academic Article	P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells.
Academic Article	Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension.
Academic Article	Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.
Academic Article	cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration.
Academic Article	Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures.
Academic Article	Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia.
Academic Article	Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGF? receptor-JNK1 signalling.
Academic Article	Validation of a pressure diameter method for determining modulus and strain of collagen engagement for long branches of bovine pulmonary arteries.
Academic Article	High pulsatility flow stimulates smooth muscle cell hypertrophy and contractile protein expression.
Academic Article	Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension.
Academic Article	Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension.
Academic Article	Enhanced growth capacity of neonatal pulmonary artery smooth muscle cells in vitro: dependence on cell size, time from birth, insulin-like growth factor I, and auto-activation of protein kinase C.
Academic Article	Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts.
Academic Article	Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.
Academic Article	Heterogeneity in the proliferative response of bovine pulmonary artery smooth muscle cells to mitogens and hypoxia: importance of protein kinase C.
Academic Article	Alteration of the pulsatile load in the high-altitude calf model of pulmonary hypertension.
Academic Article	Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase c isozymes.
Academic Article	Pulmonary vascular impedance and wave reflections in the hypoxic calf.
Academic Article	Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation.
Academic Article	Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves.
Academic Article	Alpha-skeletal actin messenger RNA increases in acute right ventricular hypertrophy.
Academic Article	Insulin-like growth factor I and protein kinase C activation stimulate pulmonary artery smooth muscle cell proliferation through separate but synergistic pathways.
Academic Article	High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells.
Academic Article	Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors.
Academic Article	PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells.
Academic Article	In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation.
Academic Article	Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia.
Academic Article	Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization.
Academic Article	A microstructurally driven model for pulmonary artery tissue.
Academic Article	Linked opening angle and histological and mechanical aspects of the proximal pulmonary arteries of healthy and pulmonary hypertensive rats and calves.
Academic Article	Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells.
Academic Article	Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.
Academic Article	Response of lobar vessels to hypoxic pulmonary hypertension.
Academic Article	Insulin-like growth factor I stimulates elastin synthesis by bovine pulmonary arterial smooth muscle cells.
Academic Article	Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m.
Academic Article	Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.
Academic Article	Adenosine A1 receptors promote vasa vasorum endothelial cell barrier integrity via Gi and Akt-dependent actin cytoskeleton remodeling.
Academic Article	Vascular remodeling in neonatal pulmonary hypertension. Role of the smooth muscle cell.
Concept	Cattle
Concept	Cattle Diseases
Academic Article	MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
Academic Article	High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization.
Academic Article	Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.
Academic Article	Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-?B pathway.
Academic Article	Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction.
Academic Article	Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.
Academic Article	The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
Academic Article	MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension.
Academic Article	The altitude at which a calf is born and raised influences the rate at which mean pulmonary arterial pressure increases with age.
Academic Article	Right Ventricular Longitudinal Strain Is Depressed in a Bovine Model of Pulmonary Hypertension.
Academic Article	Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
Academic Article	Glycolysis and oxidative phosphorylation are essential for purinergic receptor-mediated angiogenic responses in vasa vasorum endothelial cells.
Academic Article	Static and dynamic components of right ventricular afterload are negatively associated with calf survival at high altitude.
Academic Article	Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting.
Academic Article	TGF-? activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
Academic Article	A photoclickable peptide microarray platform for facile and rapid screening of 3-D tissue microenvironments.
Academic Article	Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
Academic Article	Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease.
Academic Article	Layer-specific arterial micromechanics and microstructure: Influences of age, anatomical location, and processing technique.
Academic Article	The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation.
Academic Article	Extracellular adenosine enhances pulmonary artery vasa vasorum endothelial cell barrier function via Gi/ELMO1/Rac1/PKA-dependent signaling mechanisms.
Academic Article	Characterizing the impact of altitude and finishing system on mean pulmonary arterial pressure and carcass characteristics in Angus cattle.
Academic Article	Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.
Academic Article	Isolation of vasa vasorum endothelial cells from pulmonary artery adventitia: Implementation to vascular biology research.
Academic Article	Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model.
Academic Article	SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension.
Academic Article	Microenvironmental regulation of T-cells in pulmonary hypertension.

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