Item Type | Name |
Academic Article
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Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.
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Academic Article
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Actions of lipoxygenase metabolites in isolated rat lungs.
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Academic Article
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Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.
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Academic Article
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Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media.
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Academic Article
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Persistent pulmonary hypertension of the newborn.
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Academic Article
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Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo.
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Academic Article
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Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension.
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Academic Article
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Diethylcarbamazine inhibits acute and chronic hypoxic pulmonary hypertension in awake rats.
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Academic Article
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Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension.
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Academic Article
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Progressive loss of vasodilator responsive component of pulmonary hypertension in neonatal calves exposed to 4,570 m.
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Academic Article
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Functional and structural adaptation of the yak pulmonary circulation to residence at high altitude.
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Academic Article
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Expression and localization of tropoelastin mRNA in the developing bovine pulmonary artery is dependent on vascular cell phenotype.
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Academic Article
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Alterations in extracellular matrix protein expression in neonatal pulmonary hypertension: implications for vascular function.
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Academic Article
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Hypoxia increases bromodeoxyuridine labeling indices in bovine neonatal pulmonary arteries.
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Academic Article
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Leukotriene C4 and D4 in neonates with hypoxemia and pulmonary hypertension.
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Academic Article
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Cellular and molecular mechanisms of pulmonary vascular remodeling.
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Academic Article
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Selected isozymes of PKC contribute to augmented growth of fetal and neonatal bovine PA adventitial fibroblasts.
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Academic Article
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Right ventricular angiotensin converting enzyme activity and expression is increased during hypoxic pulmonary hypertension.
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Academic Article
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Smooth muscle cell heterogeneity in pulmonary and systemic vessels. Importance in vascular disease.
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Academic Article
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Role of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension.
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Academic Article
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Enhanced growth of fetal and neonatal pulmonary artery adventitial fibroblasts is dependent on protein kinase C.
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Academic Article
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Hypoxia stimulates proliferation of a unique cell population isolated from the bovine vascular media.
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Academic Article
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The Ca2+-dependent isozymes of protein kinase C are uniquely important in the enhanced growth of immature adventitial fibroblasts isolated from the bovine pulmonary arterial wall at a time of heightened susceptibility to vascular injury.
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Academic Article
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Smooth muscle cell heterogeneity: role of specific smooth muscle cell subpopulations in pulmonary vascular disease.
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Academic Article
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Smooth muscle cells isolated from discrete compartments of the mature vascular media exhibit unique phenotypes and distinct growth capabilities.
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Academic Article
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Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung.
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Academic Article
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Hypoxic growth of bovine pulmonary artery smooth muscle cells: dependence on synergy, heterogeneity, and injury-induced phenotypic change.
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Academic Article
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Respiratory syncytial virus infects the Bonnet monkey, Macaca radiata.
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Academic Article
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Relationship between perlecan and tropoelastin gene expression and cell replication in the developing rat pulmonary vasculature.
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Academic Article
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Mechanisms regulating cAMP-mediated growth of bovine neonatal pulmonary artery smooth muscle cells.
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Academic Article
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Hypoxia induces cell-specific changes in gene expression in vascular wall cells: implications for pulmonary hypertension.
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Academic Article
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Transforming growth factor-beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries.
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Academic Article
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Myocyte cytoskeletal disorganization and right heart failure in hypoxia-induced neonatal pulmonary hypertension.
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Academic Article
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Unique growth properties of neonatal pulmonary vascular cells: importance of time- and site-specific responses, cell-cell interaction, and synergy.
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Academic Article
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Novel embryonic genes are preferentially expressed by autonomously replicating rat embryonic and neointimal smooth muscle cells.
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Academic Article
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Hypoxia-induced pulmonary vascular remodeling: contribution of the adventitial fibroblasts.
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Academic Article
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Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases.
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Academic Article
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Pulmonary artery smooth muscle cells from chronically hypoxic neonatal calves retain fetal-like and acquire new growth properties.
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Academic Article
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Hypoxia-induced inhibition of tropoelastin synthesis by neonatal calf pulmonary artery smooth muscle cells.
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Academic Article
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Bromodeoxyuridine labeling and DNA content of pulmonary arterial medial cells from hypoxia-exposed and nonexposed healthy calves.
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Academic Article
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Hypoxia-induced pulmonary artery adventitial remodeling and neovascularization: contribution of progenitor cells.
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Academic Article
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Hypoxic activation of adventitial fibroblasts: role in vascular remodeling.
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Academic Article
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Lung endothelial cell proliferation in normal and pulmonary hypertensive neonatal calves.
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Academic Article
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Perlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signaling.
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Academic Article
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Bovine distal pulmonary arterial media is composed of a uniform population of well-differentiated smooth muscle cells with low proliferative capabilities.
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Academic Article
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Yin and Yang of an endothelial cell: from normal to the extreme in growth, secretion, and transdifferentiation capabilities.
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Academic Article
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Endothelin B receptor deficiency predisposes to pulmonary edema formation via increased lung vascular endothelial cell growth factor expression.
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Academic Article
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Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts.
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Academic Article
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Cellular adaptation during chronic neonatal hypoxic pulmonary hypertension.
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Academic Article
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Hypoxia, leukocytes, and the pulmonary circulation.
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Academic Article
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Neonatal calves develop airflow limitation due to chronic hypobaric hypoxia.
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Academic Article
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Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia.
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Academic Article
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Changes in lung eicosanoid content during normal and abnormal transition in perinatal lambs.
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Academic Article
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Determination of transforming growth factor-beta mRNA levels in pulmonary arteries from normal and hypoxic calves.
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Academic Article
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Connective tissue production by vascular smooth muscle in development and disease.
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Academic Article
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Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression.
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Academic Article
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Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development.
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Academic Article
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Hypoxia-induced alterations in protein kinase C zeta signaling result in augmented fibroblast proliferation.
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Academic Article
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Circulating mononuclear cells with a dual, macrophage-fibroblast phenotype contribute robustly to hypoxia-induced pulmonary adventitial remodeling.
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Academic Article
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Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage.
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Academic Article
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Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: a process mediated by hypoxia and endothelin-1.
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Academic Article
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Role of the adventitia in pulmonary vascular remodeling.
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Academic Article
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Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.
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Academic Article
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Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cells.
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Academic Article
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Role of reactive oxygen species in chronic hypoxia-induced pulmonary hypertension and vascular remodeling.
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Academic Article
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Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.
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Academic Article
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Inflammation, growth factors, and pulmonary vascular remodeling.
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Academic Article
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Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment.
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Academic Article
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Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease.
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Academic Article
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Cellular and molecular basis of pulmonary arterial hypertension.
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Academic Article
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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.
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Academic Article
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Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall.
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Academic Article
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Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension.
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Academic Article
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Lung extracellular superoxide dismutase overexpression lessens bleomycin-induced pulmonary hypertension and vascular remodeling.
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Academic Article
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Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension.
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Academic Article
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Subendothelial cells from normal bovine arteries exhibit autonomous growth and constitutively activated intracellular signaling.
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Academic Article
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Sustained lung activity of a novel chimeric protein, SOD2/3, after intratracheal administration.
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Academic Article
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P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells.
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Academic Article
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Cell-based therapies in pulmonary hypertension: who, what, and when?
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Academic Article
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Lung eicosanoid metabolism.
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Academic Article
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Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension.
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Academic Article
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Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells.
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Academic Article
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Eph-A2 promotes permeability and inflammatory responses to bleomycin-induced lung injury.
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Academic Article
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Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension.
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Academic Article
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Cell-, age-, and phenotype-dependent differences in the control of gene expression.
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Academic Article
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cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration.
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Academic Article
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Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures.
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Academic Article
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Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
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Academic Article
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Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia.
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Academic Article
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Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGF? receptor-JNK1 signalling.
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Academic Article
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Validation of a pressure diameter method for determining modulus and strain of collagen engagement for long branches of bovine pulmonary arteries.
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Academic Article
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Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism.
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Academic Article
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Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa.
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Academic Article
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High pulsatility flow stimulates smooth muscle cell hypertrophy and contractile protein expression.
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Academic Article
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MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension.
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Academic Article
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The renin-angiotensin system in pulmonary hypertension.
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Academic Article
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Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension.
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Academic Article
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Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function.
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Academic Article
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Neither anticoagulant nor nonanticoagulant heparin affects monocrotaline lung injury.
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Academic Article
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Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension.
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Academic Article
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Leukotrienes in the lung circulation: actions and interactions.
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Academic Article
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Abnormal alveolar cells in monocrotaline induced pulmonary hypertension.
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Academic Article
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Leukotriene C4 production during hypoxic pulmonary vasoconstriction in isolated rat lungs.
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Academic Article
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Enhanced growth capacity of neonatal pulmonary artery smooth muscle cells in vitro: dependence on cell size, time from birth, insulin-like growth factor I, and auto-activation of protein kinase C.
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Academic Article
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Developmental regulation of angiotensin converting enzyme and angiotensin type 1 receptor in the rat pulmonary circulation.
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Academic Article
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Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts.
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Academic Article
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Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.
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Academic Article
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Heterogeneity in the proliferative response of bovine pulmonary artery smooth muscle cells to mitogens and hypoxia: importance of protein kinase C.
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Academic Article
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Endothelin-mediated increases in lung VEGF content promote vascular leak in young rats exposed to viral infection and hypoxia.
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Academic Article
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Alteration of the pulsatile load in the high-altitude calf model of pulmonary hypertension.
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Academic Article
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Transient reexpression of an embryonic autonomous growth phenotype by adult carotid artery smooth muscle cells after vascular injury.
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Academic Article
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Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase c isozymes.
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Academic Article
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Endothelin receptor blockade decreases lung water in young rats exposed to viral infection and hypoxia.
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Academic Article
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New hope for the treatment of pulmonary hypertension: novel approaches to a complex disease.
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Academic Article
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Pulmonary vascular impedance and wave reflections in the hypoxic calf.
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Academic Article
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Hypoxia decreases lung neprilysin expression and increases pulmonary vascular leak.
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Academic Article
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Insulin-like growth factor I and pulmonary hypertension induced by continuous air embolization in sheep.
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Academic Article
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Lung vascular development: breathing new life into an old problem.
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Academic Article
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Induction of SM-alpha-actin expression by mechanical strain in adult vascular smooth muscle cells is mediated through activation of JNK and p38 MAP kinase.
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Academic Article
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Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.
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Academic Article
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Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation.
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Academic Article
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Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension.
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Academic Article
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Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal?
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Academic Article
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Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling.
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Academic Article
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Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms.
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Academic Article
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Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves.
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Academic Article
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Alpha-skeletal actin messenger RNA increases in acute right ventricular hypertrophy.
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Academic Article
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Insulin-like growth factor I and protein kinase C activation stimulate pulmonary artery smooth muscle cell proliferation through separate but synergistic pathways.
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Academic Article
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High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells.
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Academic Article
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Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors.
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Academic Article
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PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells.
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Academic Article
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In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation.
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Academic Article
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Emerging therapies for the treatment of pulmonary hypertension.
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Academic Article
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Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia.
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Academic Article
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Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.
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Academic Article
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Leukotrienes and prostaglandins in fetal lung liquid.
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Academic Article
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Fibrocytes: potential new therapeutic targets for pulmonary hypertension?
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Academic Article
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Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization.
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Academic Article
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A microstructurally driven model for pulmonary artery tissue.
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Academic Article
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Linked opening angle and histological and mechanical aspects of the proximal pulmonary arteries of healthy and pulmonary hypertensive rats and calves.
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Academic Article
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Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells.
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Academic Article
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Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia.
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Academic Article
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Response of lobar vessels to hypoxic pulmonary hypertension.
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Academic Article
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Response to letter regarding article, ?histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid?.
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Academic Article
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Insulin-like growth factor I stimulates elastin synthesis by bovine pulmonary arterial smooth muscle cells.
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Academic Article
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Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m.
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Academic Article
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Physiologic and molecular consequences of endothelial Bmpr2 mutation.
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Academic Article
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Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.
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Academic Article
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Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.
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Academic Article
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The adventitia: essential regulator of vascular wall structure and function.
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Academic Article
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Adenosine A1 receptors promote vasa vasorum endothelial cell barrier integrity via Gi and Akt-dependent actin cytoskeleton remodeling.
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Academic Article
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Vascular remodeling in neonatal pulmonary hypertension. Role of the smooth muscle cell.
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Academic Article
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[Inhibition of hypoxic pulmonary vasoconstriction by leukotriene blockade].
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Concept
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Animals, Congenic
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Concept
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Disease Models, Animal
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Concept
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Animals, Newborn
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Concept
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Models, Animal
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Concept
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Animals
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Concept
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Animals, Genetically Modified
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Academic Article
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Bronchus-associated lymphoid tissue in pulmonary hypertension produces pathologic autoantibodies.
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Academic Article
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MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.
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Academic Article
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Relevant issues in the pathology and pathobiology of pulmonary hypertension.
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Academic Article
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Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes.
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Academic Article
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High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization.
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Academic Article
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Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.
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Academic Article
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Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.
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Academic Article
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Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-?B pathway.
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Academic Article
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Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension.
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Academic Article
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Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction.
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Academic Article
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Chemotherapy-induced pulmonary hypertension: role of alkylating agents.
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Academic Article
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The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.
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Academic Article
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Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration.
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Academic Article
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Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.
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Academic Article
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The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
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Academic Article
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Coming to terms with tissue engineering and regenerative medicine in the lung.
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Academic Article
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MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension.
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Academic Article
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The altitude at which a calf is born and raised influences the rate at which mean pulmonary arterial pressure increases with age.
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Academic Article
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Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension.
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Academic Article
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Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension.
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Academic Article
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Right Ventricular Longitudinal Strain Is Depressed in a Bovine Model of Pulmonary Hypertension.
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Academic Article
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Pulmonary Veno-occlusive Disease and Pulmonary Hypertension in Dogs: Striking Similarities to the Human Condition.
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Academic Article
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Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
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Academic Article
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Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension.
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Academic Article
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Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.
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Academic Article
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Superoxide Dismutase 3 R213G Single-Nucleotide Polymorphism Blocks Murine Bleomycin-Induced Fibrosis and Promotes Resolution of Inflammation.
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Academic Article
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Glycolysis and oxidative phosphorylation are essential for purinergic receptor-mediated angiogenic responses in vasa vasorum endothelial cells.
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Academic Article
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Static and dynamic components of right ventricular afterload are negatively associated with calf survival at high altitude.
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Academic Article
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Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting.
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Academic Article
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Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation.
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Academic Article
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Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency.
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Academic Article
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Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH).
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Grant
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Fibroblasts and Mononuclear Fibrogenic Cells Drive Right Ventricular Pulmonary Ar
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Grant
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Translational Pulmonary Vascular Biology Program
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Grant
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Lung Vascular Disease in Infants and Children: Mechanisms and Treatment
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Grant
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Adaptation to Hypoxia
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Grant
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LUNG LIPIDS IN NEONATAL PULMONARY HYPERTENSIVE DISEASES
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Academic Article
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A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.
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Academic Article
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TGF-? activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
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Academic Article
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Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming.
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Academic Article
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A photoclickable peptide microarray platform for facile and rapid screening of 3-D tissue microenvironments.
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Academic Article
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Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
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Academic Article
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Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.
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Academic Article
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Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension.
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Academic Article
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Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension.
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Academic Article
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Impact of cell-free hemoglobin on contracting skeletal muscle microvascular oxygen pressure dynamics.
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Academic Article
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Repurposing rosiglitazone, a PPAR-? agonist and oral antidiabetic, as an inhaled formulation, for the treatment of PAH.
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Academic Article
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Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension.
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Academic Article
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Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension.
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Academic Article
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Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anaemia.
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Academic Article
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Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease.
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Academic Article
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Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling.
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Academic Article
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Tissue-informed engineering strategies for modeling human pulmonary diseases.
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Academic Article
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Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives.
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Academic Article
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Pre-clinical assessment of a water-in-fluorocarbon emulsion for the treatment of pulmonary vascular diseases.
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Academic Article
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Layer-specific arterial micromechanics and microstructure: Influences of age, anatomical location, and processing technique.
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Academic Article
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CAR, a Homing Peptide, Prolongs Pulmonary Preferential Vasodilation by Increasing Pulmonary Retention and Reducing Systemic Absorption of Liposomal Fasudil.
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Academic Article
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The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation.
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Academic Article
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An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease.
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Academic Article
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Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.
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Academic Article
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Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
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Academic Article
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Redistribution of EC-SOD resolves bleomycin-induced inflammation via increased apoptosis of recruited alveolar macrophages.
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Academic Article
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Role of Inflammatory Cell Subtypes in Heart Failure.
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Academic Article
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Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension.
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Academic Article
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A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.
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Academic Article
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Pluripotent hematopoietic stem cells augment a-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension.
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Academic Article
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Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
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Academic Article
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Perspective: pathobiological paradigms in pulmonary hypertension, time for reappraisal.
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Academic Article
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Band on the run: insights into right ventricular reverse remodelling.
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Academic Article
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Extracellular adenosine enhances pulmonary artery vasa vasorum endothelial cell barrier function via Gi/ELMO1/Rac1/PKA-dependent signaling mechanisms.
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Academic Article
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RNA-Binding Proteins in Pulmonary Hypertension.
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Academic Article
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The effect of dietary nitrate supplementation on the speed-duration relationship in mice with sickle cell disease.
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Academic Article
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Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application.
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Academic Article
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P2Y Purinergic Receptors, Endothelial Dysfunction, and Cardiovascular Diseases.
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Academic Article
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Platelet activation contributes to hypoxia-induced inflammation.
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Academic Article
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17?-Estradiol and estrogen receptor a protect right ventricular function in pulmonary hypertension via BMPR2 and apelin.
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Academic Article
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Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension.
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Academic Article
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Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.
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Academic Article
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Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin.
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Academic Article
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Mechanisms Contributing to the Dysregulation of miRNA-124 in Pulmonary Hypertension.
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Academic Article
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Endothelial cell PHD2-HIF1a-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension.
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Academic Article
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The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension.
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Academic Article
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Complement-containing small extracellular vesicles from adventitial fibroblasts induce proinflammatory and metabolic reprogramming in macrophages.
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Academic Article
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Metabolite G-Protein Coupled Receptors in Cardio-Metabolic Diseases.
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Academic Article
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Perspectives on Cognitive Phenotypes and Models of Vascular Disease.
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Academic Article
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Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia.
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Academic Article
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HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury.
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Isolation of vasa vasorum endothelial cells from pulmonary artery adventitia: Implementation to vascular biology research.
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The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension.
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Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model.
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Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension.
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PFKFB3 Inhibits Fructose Metabolism in Pulmonary Microvascular Endothelial Cells.
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Characterizing the Spatiotemporal Transcriptomic Response of the Right Ventricle to Acute Pressure Overload.
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SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension.
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Microenvironmental regulation of T-cells in pulmonary hypertension.
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Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury.
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Pericytes contribute to pulmonary vascular remodeling via HIF2a signaling.
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