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Search Results to Jed N. Lampe

This is a "connection" page, showing the details of why an item matched the keywords from your search.


One or more keywords matched the following items that are connected to Lampe, Jed

Item TypeName
Concept Cytochromes b5
Concept Cytochrome P-450 Enzyme System
Concept Cytochrome P-450 CYP3A
Concept Cytochrome P-450 Enzyme Inhibitors
Concept Cytochrome P-450 CYP3A Inhibitors
Academic Article Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.
Academic Article Cytochrome P450 Enzyme Metabolites in Lead Discovery and Development.
Academic Article Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4.
Academic Article Probing the CYP3A4 active site by cysteine scanning mutagenesis and photoaffinity labeling.
Academic Article Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.
Academic Article Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.
Academic Article Active-site residues move independently from the rest of the protein in a 200 ns molecular dynamics simulation of cytochrome P450 CYP119.
Academic Article Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicity.
Academic Article Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase.
Academic Article NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity.
Academic Article Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates.
Academic Article Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4.
Academic Article Spectral resolution of a second binding site for Nile Red on cytochrome P4503A4.
Grant The role of CYP3A7 in the disposition and Toxicity of HIV inhibitors in the developing infant
Academic Article Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism.
Grant The role of CYP3A7 in the disposition and toxicity of HIV inhibitors in the developing infant
Academic Article Inhibition of CYP3A7 DHEA-S Oxidation by Lopinavir and Ritonavir: An Alternative Mechanism for Adrenal Impairment in HIV Antiretroviral-Treated Neonates.
Academic Article Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening.
Academic Article Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE.
Academic Article Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement.

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