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Search Results to Siddhartha Shankar Mitra

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One or more keywords matched the following properties of Mitra, Siddhartha

overview Dr. Mitra is currently an Assistant professor of pediatrics at the University of Colorado School of medicine and Children’s Hospital Colorado in the Division of hematology-oncology and bone marrow transplant. He was previously a Senior Scientist at the Stanford Institute for stem cell biology and regenerative medicine and the Ludwig center for cancer stem cell research and medicine. He earned his B.Sc.(Hons) and M.Sc.(Hons) from the basic medical sciences honors school program at Panjab University in Chandigarh, India. In 1999 he joined the graduate program at the State University of New York at Buffalo where he completed a Ph.D. in Molecular Cell biology. He went on to do his postdoctoral training in developmental neurobiology at the center for neuroscience at the University of California, Davis, and then at the brain tumor research laboratories at Stanford University School of Medicine. In 2010 he was appointed as a Senior Scientist at the Stanford Institute for Stem Cell Research and Regenerative Medicine to head the CNS immuno-therapeutics program. In 2016 he was appointed as the director for Translational NeuroOncology at Lucille Packard Children’s Hospital and Stanford University Medical Center. In 2018 The Mitra laboratory moved to the University of Colorado, School of Medicine at Denver. A major goal within the laboratory is to understand the molecular physiology of immune cells within tumors and to identify mechanisms that define the biology of immune cell communities within brain tumors. The research interests primarily pertain to the immune-microenvironment of malignant brain tumors with a specific interest in overcoming immune evasion mechanisms in CNS malignancies.

One or more keywords matched the following items that are connected to Mitra, Siddhartha

Item TypeName
Concept Brain Neoplasms
Academic Article Disrupting the CD47-SIRPa anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.
Academic Article Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion.
Academic Article Glioblastoma stem cells and stem cell-targeting immunotherapies.
Academic Article Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway.
Academic Article Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.
Academic Article Casein kinase 2a regulates glioblastoma brain tumor-initiating cell growth through the ?-catenin pathway.
Academic Article Pineal parenchymal tumor of intermediate differentiation: clinicopathological report and analysis of epidermal growth factor receptor variant III expression.
Academic Article Passive antibody-mediated immunotherapy for the treatment of malignant gliomas.
Academic Article The epidermal growth factor variant III peptide vaccine for treatment of malignant gliomas.
Academic Article Microglia are effector cells of CD47-SIRPa antiphagocytic axis disruption against glioblastoma.
Academic Article CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.
Academic Article Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation.
Academic Article Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.
Academic Article Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
Academic Article Microglia in the Brain Tumor Microenvironment.
Academic Article New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs.
Academic Article Mapping the tumor-infiltrating immune cells during glioblastoma progression.
Academic Article Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma.

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  • Brain Neoplasms

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