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Search Results to Siddhartha Shankar Mitra

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Mitra, Siddhartha

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Dr. Mitra is currently an Assistant professor of pediatrics at the University of Colorado School of medicine and Children’s Hospital Colorado in the Division of hematology-oncology and bone marrow transplant. He was previously a Senior Scientist at the Stanford Institute for stem cell biology and regenerative medicine and the Ludwig center for cancer stem cell research and medicine. He earned his B.Sc.(Hons) and M.Sc.(Hons) from the basic medical sciences honors school program at Panjab University in Chandigarh, India. In 1999 he joined the graduate program at the State University of New York at Buffalo where he completed a Ph.D. in Molecular Cell biology. He went on to do his postdoctoral training in developmental neurobiology at the center for neuroscience at the University of California, Davis, and then at the brain tumor research laboratories at Stanford University School of Medicine. In 2010 he was appointed as a Senior Scientist at the Stanford Institute for Stem Cell Research and Regenerative Medicine to head the CNS immuno-therapeutics program. In 2016 he was appointed as the director for Translational NeuroOncology at Lucille Packard Children’s Hospital and Stanford University Medical Center. In 2018 The Mitra laboratory moved to the University of Colorado, School of Medicine at Denver. A major goal within the laboratory is to understand the molecular physiology of immune cells within tumors and to identify mechanisms that define the biology of immune cell communities within brain tumors. The research interests primarily pertain to the immune-microenvironment of malignant brain tumors with a specific interest in overcoming immune evasion mechanisms in CNS malignancies.

One or more keywords matched the following items that are connected to Mitra, Siddhartha

Item Type	Name
Concept	Brain Neoplasms
Academic Article	Disrupting the CD47-SIRPa anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.
Academic Article	Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion.
Academic Article	Glioblastoma stem cells and stem cell-targeting immunotherapies.
Academic Article	Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway.
Academic Article	Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.
Academic Article	Casein kinase 2a regulates glioblastoma brain tumor-initiating cell growth through the ?-catenin pathway.
Academic Article	Pineal parenchymal tumor of intermediate differentiation: clinicopathological report and analysis of epidermal growth factor receptor variant III expression.
Academic Article	Passive antibody-mediated immunotherapy for the treatment of malignant gliomas.
Academic Article	The epidermal growth factor variant III peptide vaccine for treatment of malignant gliomas.
Academic Article	Microglia are effector cells of CD47-SIRPa antiphagocytic axis disruption against glioblastoma.
Academic Article	CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.
Academic Article	Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation.
Academic Article	Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.
Academic Article	Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
Academic Article	Microglia in the Brain Tumor Microenvironment.
Academic Article	New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs.
Academic Article	Mapping the tumor-infiltrating immune cells during glioblastoma progression.
Academic Article	Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma.

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Brain Neoplasms