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Search Results to Michael Richard Verneris

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Verneris, Michael

One or more keywords matched the following properties of Verneris, Michael

Property	Value
keywords	NK cells
keywords	T Cells
overview	Our laboratory is focused on using the immune system to target and treat cancer. Active projects in the laboratory include: 1) Chimeric antigen receptor expressing T cell (CART) homing to solid tumors 2) Chimeric antigen receptor expressing iPS and ES cells that are differentiated into natural killer (NK) and T cells 3) Animal models of bone marrow transplantation

One or more keywords matched the following items that are connected to Verneris, Michael

Item Type	Name
Concept	Jurkat Cells
Concept	Hematopoietic Stem Cells
Concept	Precursor Cells, B-Lymphoid
Concept	Lymphocytes
Concept	T-Lymphocytes, Cytotoxic
Concept	Neoplastic Stem Cells
Concept	Erythroid Precursor Cells
Concept	CD8-Positive T-Lymphocytes
Concept	T-Lymphocytes, Helper-Inducer
Concept	HL-60 Cells
Concept	Myeloid Progenitor Cells
Concept	K562 Cells
Concept	Th1 Cells
Concept	Dendritic Cells
Concept	T-Lymphocytes, Regulatory
Concept	CD4-Positive T-Lymphocytes
Concept	Killer Cells, Lymphokine-Activated
Concept	Stromal Cells
Concept	Embryonic Stem Cells
Concept	B-Lymphocytes
Concept	Tumor Cells, Cultured
Concept	Lymphoid Progenitor Cells
Concept	Bone Marrow Cells
Concept	Pluripotent Stem Cells
Concept	Myeloid Cells
Concept	Killer Cells, Natural
Concept	HT29 Cells
Concept	Cells, Cultured
Concept	Stem Cells
Concept	T-Lymphocytes
Concept	Natural Killer T-Cells
Academic Article	NK cell education after allogeneic transplantation: dissociation between recovery of cytokine-producing and cytotoxic functions.
Academic Article	Lymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI alone.
Academic Article	The effects of 1,25-dihydroxyvitamin D3 on in vitro human NK cell development from hematopoietic stem cells.
Academic Article	The phenotypic and functional characteristics of umbilical cord blood and peripheral blood natural killer cells.
Academic Article	The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer.
Academic Article	Use of natural killer cells as immunotherapy for leukaemia.
Academic Article	Natural killer cells and regulatory T cells: how to manipulate a graft for optimal GVL.
Academic Article	Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation.
Academic Article	Notch signaling at later stages of NK cell development enhances KIR expression and functional maturation.
Academic Article	Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Transplantation.
Academic Article	Umbilical cord blood T cells express multiple natural cytotoxicity receptors after IL-15 stimulation, but only NKp30 is functional.
Academic Article	Reduced-intensity conditioning followed by related allografts in hematologic malignancies: long-term outcomes most successful in indolent and aggressive non-Hodgkin lymphomas.
Academic Article	Peritransplant palifermin use and lymphocyte recovery after T-cell replete, matched related allogeneic hematopoietic cell transplantation.
Academic Article	Natural killer-cell differentiation by myeloid progenitors.
Academic Article	Heterodimeric bispecific single-chain variable-fragment antibodies against EpCAM and CD16 induce effective antibody-dependent cellular cytotoxicity against human carcinoma cells.
Academic Article	Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells.
Academic Article	The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT).
Academic Article	Natural killer cell consolidation for acute myelogenous leukemia: a cell therapy ready for prime time?
Academic Article	Natural killer cell killing of acute myelogenous leukemia and acute lymphoblastic leukemia blasts by killer cell immunoglobulin-like receptor-negative natural killer cells after NKG2A and LIR-1 blockade.
Academic Article	A randomized trial of one versus two doses of influenza vaccine after allogeneic transplantation.
Academic Article	Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition.
Academic Article	Impact of bone marrow hematogones on umbilical cord blood transplantation outcomes in patients with acute myeloid leukemia.
Academic Article	Low levels of Her2/neu expressed by Ewing's family tumor cell lines can redirect cytokine-induced killer cells.
Academic Article	Clinical utility of natural killer cells in cancer therapy and transplantation.
Academic Article	Development of IL-22-producing NK lineage cells from umbilical cord blood hematopoietic stem cells in the absence of secondary lymphoid tissue.
Academic Article	Immunotherapy for pediatric cancer.
Academic Article	Natural killer cell differentiation from hematopoietic stem cells: a comparative analysis of heparin- and stromal cell-supported methods.
Academic Article	CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets.
Academic Article	Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function.
Academic Article	Studies of ex vivo activated and expanded CD8+ NK-T cells in humans and mice.
Academic Article	The role of oxidant injury in the pathophysiology of human thalassemias.
Academic Article	Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein.
Academic Article	Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells.
Academic Article	Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity.
Academic Article	Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production.
Academic Article	Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen.
Academic Article	Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect.
Academic Article	Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in?vivo cytokine administration: implications for clinical therapy.
Academic Article	Natural Killer Cell Adoptive Transfer Therapy: Exploiting the First Line of Defense Against Cancer.
Academic Article	Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9.
Academic Article	iTRAQ is a useful method to screen for membrane-bound proteins differentially expressed in human natural killer cell types.
Academic Article	Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT.
Academic Article	Marrow damage and hematopoietic recovery following allogeneic bone marrow transplantation for acute leukemias: Effect of radiation dose and conditioning regimen.
Academic Article	Killing the killer: natural killer cells to treat Ewing's sarcoma.
Academic Article	Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells.
Academic Article	Phase I study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies.
Academic Article	Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy.
Academic Article	Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease.
Academic Article	The unexpected effect of cyclosporin A on CD56+CD16- and CD56+CD16+ natural killer cell subpopulations.
Academic Article	IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function.
Academic Article	Lineage relationships of human interleukin-22-producing CD56+ ROR?t+ innate lymphoid cells and conventional natural killer cells.
Academic Article	Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression.
Academic Article	CD56(dim)CD16(+) NK cells downregulate CD16 following target cell induced activation of matrix metalloproteinases.
Academic Article	CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT.
Academic Article	Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis.
Academic Article	Visualization of tumor growth and response to NK-T cell based immunotherapy using bioluminescence.
Academic Article	Survivin expression correlates with apoptosis resistance after lymphocyte activation and is found preferentially in memory T cells.
Academic Article	Expansion of cytolytic CD8(+) natural killer T cells with limited capacity for graft-versus-host disease induction due to interferon gamma production.
Academic Article	Lymphodepleting chemotherapy with donor lymphocyte infusion post-allogeneic HCT for hematological malignancies is associated with severe, but therapy-responsive aGvHD.
Academic Article	Hodgkin disease-derived cell lines expressing ubiquitous mitochondrial creatine kinase show growth inhibition by cyclocreatine treatment independent of apoptosis.
Academic Article	Engineering hematopoietic grafts: purified allogeneic hematopoietic stem cells plus expanded CD8+ NK-T cells in the treatment of lymphoma.
Academic Article	Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells.
Academic Article	CD4+ T Cells Coexpressing CD134 (OX40) Harbor Significantly Increased Levels of Human Herpesvirus 6B DNA Following Umbilical Cord Blood Transplantation.
Academic Article	Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity.
Academic Article	Recipient HLA-C Haplotypes and microRNA 148a/b Binding Sites Have No Impact on Allogeneic Hematopoietic Cell Transplantation Outcomes.
Academic Article	A subset of virus-specific CD161+ T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in AML.
Academic Article	Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models.
Grant	Genetic epidemiology of hematopoietic cell transplant outcomes
Grant	ACTIVITY OF EXPANDED GAMMA/DELTA T CELLS
Grant	Biomarkers In Pediatric Versus Adult Myelodysplastic Syndromes
Grant	Lymphoid Tissue Inducer/NK22 Cells and Post-transplant Immune Recovery
Academic Article	Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells.
Academic Article	Dendritic Cell Recovery Impacts Outcomes after Umbilical Cord Blood and Sibling Donor Transplantation for Hematologic Malignancies.
Academic Article	Recipient T Cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells.
Academic Article	Fewer Circulating Natural Killer Cells 28 Days After Double Cord Blood Transplantation Predicts Inferior Survival and IL-15 Response.
Academic Article	First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation.
Academic Article	Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD.
Academic Article	Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia.
Concept	Myeloid-Derived Suppressor Cells
Concept	HEK293 Cells
Academic Article	Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation.
Academic Article	A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.
Academic Article	Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.
Academic Article	Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function.
Academic Article	Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage.
Academic Article	Human innate lymphoid cell precursors express CD48 that modulates ILC differentiation through 2B4 signaling.
Grant	Characterizing Innate Immune Dysregulation in Tonsils of Individuals with Down Syndrome
Academic Article	Therapeutic manipulation of innate lymphoid cells.
Academic Article	Perspectives on outpatient administration of CAR-T cell therapy in aggressive B-cell lymphoma and acute lymphoblastic leukemia.
Academic Article	Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen Receptor Consortium Report.
Academic Article	SAHA Enhances Differentiation of CD34+CD45+ Hematopoietic Stem and Progenitor Cells from Pluripotent Stem Cells Concomitant with an Increase in Hemogenic Endothelium.
Academic Article	Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells.
Academic Article	Higher doses of tisagenlecleucel are associated with improved outcomes: a report from the pediatric real-world CAR consortium.
Academic Article	Outcomes After Nonresponse and Relapse Post-Tisagenlecleucel in Children, Adolescents, and Young Adults With B-Cell Acute Lymphoblastic Leukemia.
Academic Article	HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL.
Academic Article	Practice Preferences for Consolidative Hematopoietic Stem Cell Transplantation Following Tisagenlecleucel in Children and Young Adults with B Cell Acute Lymphoblastic Leukemia.
Academic Article	Tisagenlecleucel utilisation and outcomes across refractory, first relapse and multiply relapsed B-cell acute lymphoblastic leukemia: a retrospective analysis of real-world patterns.

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B Lymphocytes