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Search Results to Leslie Lange

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One or more keywords matched the following items that are connected to Lange, Leslie

Item TypeName
Academic Article Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
Concept Polymorphism, Single Nucleotide
Academic Article Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Academic Article Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
Academic Article Soluble CD14: genomewide association analysis and relationship to cardiovascular risk and mortality in older adults.
Academic Article Polymorphisms in the prostate-specific antigen gene promoter do not predict serum prostate-specific antigen levels in African-American men.
Academic Article Screen time behaviours may interact with obesity genes, independent of physical activity, to influence adolescent BMI in an ethnically diverse cohort.
Academic Article Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
Academic Article Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Academic Article Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.
Academic Article A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects.
Academic Article A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium.
Academic Article Influence of SNP*SNP interaction on BMI in European American adolescents: findings from the National Longitudinal Study of Adolescent Health.
Academic Article Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
Academic Article Biological, clinical and population relevance of 95 loci for blood lipids.
Academic Article Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults.
Academic Article Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.
Academic Article Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ.
Academic Article Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.
Academic Article Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation.
Academic Article Family-based samples can play an important role in genetic association studies.
Academic Article Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples.
Academic Article Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.
Academic Article Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans.
Academic Article Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe).
Academic Article Association of polymorphisms in CASP10 and CASP8 with FEV(1)/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics.
Academic Article Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms.
Academic Article Moderate to vigorous physical activity interactions with genetic variants and body mass index in a large US ethnically diverse cohort.
Academic Article HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Academic Article Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults.
Academic Article A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Academic Article Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.
Academic Article Trans-ethnic Meta-analysis and Functional Annotation Illuminates the?Genetic Architecture of Fasting Glucose and Insulin.
Academic Article Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.
Academic Article Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascular Health Study.
Academic Article Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
Academic Article Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
Academic Article Coagulation factor?XII genetic variation, ex?vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study.
Academic Article Plasma Levels of Soluble Interleukin-2 Receptor a: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.
Academic Article Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study.
Academic Article Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults.
Academic Article Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans.
Academic Article Heritability and expression of C-reactive protein in type 2 diabetes in the Diabetes Heart Study.
Academic Article Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.
Academic Article Common genetic variants associated with plasma fibrin D-dimer concentration in older European- and African-American adults.
Academic Article Chromosome 8q24 risk variants in hereditary and non-hereditary prostate cancer patients.
Academic Article Testing genetic association with rare variants in admixed populations.
Academic Article Genetics of coronary artery calcification among African Americans, a meta-analysis.
Academic Article Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Academic Article Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
Academic Article Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health.
Academic Article NCAM1 and neurocognition in schizophrenia.
Academic Article Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events.
Academic Article Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project.
Academic Article Imputation of coding variants in African Americans: better performance using data from the exome sequencing project.
Academic Article Genome-wide association of body fat distribution in African ancestry populations suggests new loci.
Academic Article Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study.
Academic Article A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.
Academic Article Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.
Academic Article BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort.
Academic Article Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?
Academic Article Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.
Academic Article Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts.
Academic Article Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts.
Academic Article Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.
Academic Article PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites.
Academic Article Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women.
Academic Article Interaction between fibrinogen and IL-6 genetic variants and associations with cardiovascular disease risk in the Cardiovascular Health Study.
Academic Article Recent developments in genome and exome-wide analyses of plasma lipids.
Academic Article Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study.
Academic Article A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering.
Academic Article Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans.
Academic Article Autosomal linkage analysis for the level of response to alcohol.
Academic Article Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.
Academic Article Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables.
Academic Article Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort.
Academic Article Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1).
Academic Article Association of exome sequences with plasma C-reactive protein levels in >9000 participants.
Academic Article Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array.
Academic Article Replication of LIN28B SNP association with age of menarche in young Filipino women.
Academic Article Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.
Academic Article Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity.
Academic Article Replication of findings on the association of genetic variation in 24 hemostasis genes and risk of incident venous thrombosis.
Academic Article Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.
Academic Article Leveraging population admixture to characterize the heritability of complex traits.
Academic Article Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.
Academic Article Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.
Academic Article Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study.
Academic Article Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans.
Academic Article Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.
Academic Article Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation.
Academic Article Mendelian randomization of blood lipids for coronary heart disease.
Academic Article IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study.
Academic Article Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study.
Academic Article The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Academic Article A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.
Academic Article Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Academic Article Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk.
Academic Article Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study.
Academic Article Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry.
Academic Article Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.
Academic Article Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans.
Academic Article Is rs7566605, a SNP near INSIG2, associated with body mass in a randomized clinical trial of antipsychotics in schizophrenia?
Academic Article A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study.
Grant Information Explorer: a Suite of Tools for Cross-study Genetic Loci Discovery
Grant Information Explorer: a Suite of Tools for Cross-study Genetic Loci Discovery
Academic Article Estrogen receptor 1 polymorphisms are associated with airway hyperresponsiveness and lung function decline, particularly in female subjects with asthma.
Academic Article Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
Academic Article Association of RGS2 and RGS5 variants with schizophrenia symptom severity.
Academic Article Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Academic Article Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
Academic Article Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans.
Academic Article Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group.
Academic Article Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
Academic Article Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Academic Article Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts.
Academic Article Association of HLA-DRB1*09:01 with tIgE levels among African-ancestry individuals with asthma.
Academic Article Genetic Risk for Hepatic Fat among an Ethnically Diverse Cohort of Youth: The Exploring Perinatal Outcomes among Children Study.
Academic Article Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
Academic Article Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.
Academic Article The Polygenic and Monogenic Basis of Blood Traits and Diseases.
Academic Article Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants.
Academic Article Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos.
Academic Article Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium.
Academic Article Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Academic Article Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
Academic Article Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.
Academic Article Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants.
Academic Article Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche.
Academic Article Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
Academic Article Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine Project.
Academic Article Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation.
Academic Article The power of genetic diversity in genome-wide association studies of lipids.
Academic Article Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.
Academic Article Protein prediction for trait mapping in diverse populations.
Academic Article Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Academic Article Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Academic Article A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program.
Academic Article Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data.
Academic Article Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.
Academic Article A saturated map of common genetic variants associated with human height.
Academic Article Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.
Academic Article NetSHy: network summarization via a hybrid approach leveraging topological properties.
Academic Article Large scale proteomic studies create novel privacy considerations.
Academic Article Mendelian randomization study of diabetes and dementia in the Million Veteran Program.
Academic Article Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Academic Article A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Academic Article Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations.
Academic Article Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals.
Academic Article Genetic insights into resting heart rate and its role in cardiovascular disease.
Academic Article Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.
Academic Article X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.

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  • Polymorphism Single Nucleotide

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