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overview Our research focuses on pediatric cardiovascular and congenital heart disease with particular emphasis on investigations of the molecular mechanisms underlying the remodeling of cardiac and immune cell metabolism, identification of novel therapeutic targets, and biomarker assessment. The ultimate goal of this research is to develop the critical knowledge base and infrastructure necessary to identify efficacious therapies for improving outcomes in patients with heart disease. The lab utilizes several unique tools to address the mechanisms of cardiac dysfunction including whole animal and cell culture-based models, as well as a meticulously preserved Pediatric Heart Tissue and Blood BioBank. Additionally, we collaborate with a variety of labs to assess parameters of mitochondrial bioenergetics in several different physiologic and pathologic processes. Learn more at https://www.GarciaLaboratory.com

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