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Search Results to Peter Ashley Gottlieb

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One or more keywords matched the following items that are connected to Gottlieb, Peter

Item TypeName
Academic Article DRB1*04 and DQ alleles: expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease.
Academic Article Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays.
Academic Article Lazarus rises: islet regeneration in the 21st century.
Academic Article Becaplermin and necrobiosis lipoidicum diabeticorum: results of a case control pilot study.
Academic Article Insulin-specific tolerance in diabetes.
Academic Article Insulin autoimmunity: prediction/precipitation/prevention type 1A diabetes.
Academic Article Insulin lispro therapy in pregnancies complicated by type 1 diabetes: glycemic control and maternal and fetal outcomes.
Academic Article Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats.
Academic Article Prediabetes: prediction and prevention trials.
Academic Article Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop.
Academic Article HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes.
Academic Article Type 1 diabetes.
Academic Article T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading.
Academic Article CD4+CD25high regulatory T cells in human autoimmune diabetes.
Academic Article Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups.
Academic Article Endocrine and immunogenetic testing in individuals with type 1 diabetes and 21-hydroxylase autoantibodies: Addison's disease in a high-risk population.
Academic Article Secondary attack rate of type 1 diabetes in Colorado families.
Academic Article Optimizing insulin therapy in pregnant women with type 1 diabetes mellitus.
Academic Article Immunomodulation in type 1 diabetes by NBI-6024, an altered peptide ligand of the insulin B epitope.
Academic Article CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.
Academic Article Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.
Academic Article No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes.
Academic Article The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes.
Academic Article Feasibility of 10-day use of a continuous glucose-monitoring system in adults with type 1 diabetes.
Academic Article Comparison of accuracy and safety of the SEVEN and the Navigator continuous glucose monitoring systems.
Academic Article Rituximab, B-lymphocyte depletion, and preservation of beta-cell function.
Academic Article Failure to preserve beta-cell function with mycophenolate mofetil and daclizumab combined therapy in patients with new- onset type 1 diabetes.
Academic Article Editorial: cystic fibrosis.
Academic Article Vitamin D deficiency and coronary artery calcification in subjects with type 1 diabetes.
Academic Article Impact of insulin lispro on HbA1c values in insulin pump users.
Academic Article Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial.
Academic Article Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative.
Academic Article Immunology of Diabetes Society T-Cell Workshop: HLA class II tetramer-directed epitope validation initiative.
Academic Article Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes.
Academic Article Cytokine and immunosuppressive therapies of type 1 diabetes mellitus.
Academic Article Testing the NKT cell hypothesis of human IDDM pathogenesis.
Academic Article Dysregulated Toll-like receptor-induced interleukin-1? and interleukin-6 responses in subjects at risk for the development of type 1 diabetes.
Academic Article No relation between cystic fibrosis-related diabetes and type 1 diabetes autoimmunity.
Academic Article Epstein-Barr and other herpesvirus infections in patients with early onset type 1 diabetes treated with daclizumab and mycophenolate mofetil.
Academic Article Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial.
Academic Article Immune therapy and ?-cell death in type 1 diabetes.
Academic Article Transient myocardial perfusion abnormalities in diabetic patients: a prospective study using thallium exercise tolerance testing.
Academic Article Mouse and man: multiple genes and multiple autoantigens in the aetiology of type I DM and related autoimmune disorders.
Academic Article T cell receptor restriction of diabetogenic autoimmune NOD T cells.
Academic Article Inflammatory markers and diabetic retinopathy in type 1 diabetes.
Academic Article Diagnosis and treatment of pre-insulin dependent diabetes.
Academic Article Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes.
Academic Article A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin.
Academic Article Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide.
Academic Article Glycemic parameters with multiple daily injections using insulin glargine versus insulin pump.
Academic Article Improved glycemic control without an increase in severe hypoglycemic episodes in intensively treated patients with type 1 diabetes receiving morning, evening, or split dose insulin glargine.
Academic Article Reduced severe hypoglycemia with insulin glargine in intensively treated adults with type 1 diabetes.
Academic Article A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes.
Academic Article Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years.
Academic Article Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes.
Academic Article Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells.
Academic Article Immunotherapy for the prevention and treatment of type 1 diabetes: human trials and a look into the future.
Academic Article Continuous home monitoring of glucose: improved glycemic control with real-life use of continuous glucose sensors in adult subjects with type 1 diabetes.
Academic Article Type 1 diabetes intervention trials 2007: where are we and where are we going?
Academic Article Improved glycemic control in intensively treated adult subjects with type 1 diabetes using insulin guidance software.
Academic Article Altered Toll-like receptor signaling pathways in human type 1 diabetes.
Academic Article Epidemiology, pathophysiology, and prognostic implications of cystic fibrosis-related diabetes: a technical review.
Academic Article Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes.
Academic Article Time lag characterization of two continuous glucose monitoring systems.
Academic Article Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8.
Academic Article Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
Academic Article Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data.
Academic Article Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation.
Academic Article Comparison of cryopreservation methods on T-cell responses to islet and control antigens from type 1 diabetic patients and controls.
Academic Article Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8? T cells in type 1 diabetes.
Academic Article Approaches to prevention and treatment of IDDM in animal models.
Concept Diabetes Mellitus, Type 1
Concept Diabetes Mellitus, Type 2
Academic Article Clinical optimization of antigen specific modulation of type 1 diabetes with the plasmid DNA platform.
Academic Article Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders.
Academic Article B-lymphocyte depletion with rituximab and ?-cell function: two-year results.
Academic Article Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment.
Academic Article Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.
Academic Article Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial.
Academic Article Chromogranin A is a T cell antigen in human type 1 diabetes.
Academic Article MAS-1 adjuvant immunotherapy generates robust Th2 type and regulatory immune responses providing long-term protection from diabetes in late-stage pre-diabetic NOD mice.
Academic Article a1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1? responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.
Academic Article Reduction in CD4 central memory T-cell subset in costimulation modulator abatacept-treated patients with recent-onset type 1 diabetes is associated with slower C-peptide decline.
Academic Article Low-dose otelixizumab anti-CD3 monoclonal antibody DEFEND-1 study: results of the randomized phase III study in recent-onset human type 1 diabetes.
Academic Article Anti-thymocyte globulin/G-CSF treatment preserves ? cell function in patients with established type 1 diabetes.
Academic Article Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.
Academic Article Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients.
Academic Article Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes.
Academic Article Development of Autoimmune-Mediated ? Cell Failure After Total Pancreatectomy With Autologous Islet Transplantation.
Academic Article What defines disease in an age of genetics and biomarkers?
Academic Article Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients.
Academic Article Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association.
Academic Article Defining pathways for development of disease-modifying therapies in children with type 1 diabetes: a consensus report.
Academic Article Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2?year results of a randomised trial.
Academic Article ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study.
Academic Article Immune Intervention and Preservation of Pancreatic Beta Cell Function in Type 1 Diabetes.
Academic Article Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects?
Academic Article Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes.
Academic Article Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
Academic Article Predominance of DR3 in Somali children with type 1 diabetes in the twin cities, Minnesota.
Academic Article The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies.
Grant IMMUNOTHERAPY TRIAL IN NEW ONSET TYPE 1 DIABETES
Grant Human TCR/HLA Transgenic Mice to Prevent T1DM
Grant TrialNet: Diabetes Type 1 Prevention Trial
Grant TrialNet: Diabetes Type 1 Prevention
Academic Article Impact of Age and Antibody Type on Progression From Single to Multiple Autoantibodies in Type 1 Diabetes Relatives.
Academic Article Understanding and preventing type 1 diabetes through the unique working model of TrialNet.
Academic Article Erratum to: Understanding and preventing type 1 diabetes through the unique working model of TrialNet.
Academic Article Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.
Academic Article Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles.
Academic Article Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.
Academic Article Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.
Academic Article Learning From Past Failures of Oral Insulin Trials.
Academic Article Low-Dose Anti-Thymocyte Globulin (ATG) Preserves ?-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes.
Academic Article Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes.
Academic Article Intestinal Metaproteomics Reveals Host-Microbiota Interactions in Subjects at Risk for Type 1 Diabetes.
Academic Article Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes.
Academic Article Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7?years from diagnosis.
Academic Article Rationally designed small molecules to prevent type 1 diabetes.
Academic Article Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data.
Academic Article Biomarker Discovery in Pre-Type 1 Diabetes; Th40 Cells as a Predictive Risk Factor.
Academic Article Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes.
Academic Article An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.
Academic Article Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes.
Academic Article Single-Cell Analysis of CD4 T Cells in Type 1 Diabetes: From Mouse to Man, How to Perform Mechanistic Studies.
Academic Article Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.
Academic Article Immunomodulatory activity of humanized anti-IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes.
Academic Article Clinical trial data validate the C-peptide estimate model in type 1 diabetes.
Academic Article Risk of Islet and Celiac Autoimmunity in Cotwins of Probands With Type 1 Diabetes.
Academic Article Exenatide extended release in patients with type 1 diabetes with and without residual insulin production.
Academic Article Endotypes in T1D: B lymphocytes and early onset.
Academic Article Advances in Diabetes Treatment - Once-Weekly Insulin.
Academic Article T-cell responses to hybrid insulin peptides prior to type 1 diabetes development.
Academic Article Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report.
Academic Article Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes.
Academic Article Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.
Academic Article Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample.
Academic Article Association of High-Affinity Autoantibodies With Type 1 Diabetes High-Risk HLA Haplotypes.
Academic Article Temporal development of T cell receptor repertoires during childhood in health and disease.
Academic Article Barriers to Screening: An Analysis of Factors Impacting Screening for Type 1 Diabetes Prevention Trials.
Academic Article Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial.
Academic Article Identification of an anergic BND cell-derived activated B cell population (BND2) in young-onset type 1 diabetes patients.
Academic Article Measuring anti-islet autoimmunity in mouse and human by profiling peripheral blood antigen-specific CD4 T cells.
Academic Article Utility and precision evidence of technology in the treatment of type 1 diabetes: a systematic review.
Academic Article Teplizumab: A Disease-Modifying Therapy for Type 1 Diabetes That Preserves ?-Cell Function.
Academic Article C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis.

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