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Search Results to Thomas R Cech

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Item TypeName
Academic Article Sequence requirements for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA.
Academic Article Sites of circularization of the Tetrahymena rRNA IVS are determined by sequence and influenced by position and secondary structure.
Academic Article Reactions of the intervening sequence of the Tetrahymena ribosomal ribonucleic acid precursor: pH dependence of cyclization and site-specific hydrolysis.
Academic Article Self-splicing RNA: implications for evolution.
Academic Article Characterization of the rapidly renaturing sequences in the main CsCl density bands of Drosophila, mouse, and human DNA.
Academic Article In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence.
Academic Article Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage-ligation reaction.
Academic Article Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena.
Academic Article Transcribed and non-transcribed regions of Tetrahymena ribosomal gene chromatin have different accessibilities to micrococcal nuclease.
Academic Article Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene in Tetrahymena thermophila.
Academic Article Fate of an intervening sequence ribonucleic acid: excision and cyclization of the Tetrahymena ribosomal ribonucleic acid intervening sequence in vivo.
Academic Article The intervening sequence excised from the ribosomal RNA precursor of Tetrahymena contains a 5-terminal guanosine residue not encoded by the DNA.
Academic Article The 2,6-diaminopurine riboside.5-methylisocytidine wobble base pair: an isoenergetic substitution for the study of G.U pairs in RNA.
Academic Article Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu).
Academic Article Efficient protein-facilitated splicing of the yeast mitochondrial bI5 intron.
Academic Article Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo.
Academic Article An important RNA tertiary interaction of group I and group II introns is implicated in gram-positive RNase P RNAs.
Academic Article Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme.
Academic Article Translocation of an RNA duplex on a ribozyme.
Academic Article Representation of the secondary and tertiary structure of group I introns.
Academic Article Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy.
Academic Article Protein facilitation of group I intron splicing by assembly of the catalytic core and the 5' splice site domain.
Academic Article Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates.
Academic Article Movement of the guide sequence during RNA catalysis by a group I ribozyme.
Academic Article The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction.
Academic Article RNA. Fishing for fresh catalysts.
Academic Article Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.
Academic Article A positive entropy change for guanosine binding and for the chemical step in the Tetrahymena ribozyme reaction.
Academic Article Telomerase RNAs of different ciliates have a common secondary structure and a permuted template.
Academic Article Two major tertiary folding transitions of the Tetrahymena catalytic RNA.
Academic Article GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain.
Academic Article Coaxially stacked RNA helices in the catalytic center of the Tetrahymena ribozyme.
Academic Article The efficiency and versatility of catalytic RNA: implications for an RNA world.
Academic Article Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding.
Academic Article The intervening sequence of the ribosomal RNA precursor is converted to a circular RNA in isolated nuclei of Tetrahymena.
Academic Article A labile phosphodiester bond at the ligation junction in a circular intervening sequence RNA.
Academic Article Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.
Academic Article Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences.
Academic Article Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity.
Academic Article Conformational switches involved in orchestrating the successive steps of group I RNA splicing.
Academic Article RNA splicing: three themes with variations.
Academic Article Conserved thermochemistry of guanosine nucleophile binding for structurally distinct group I ribozymes.
Academic Article Mitochondrial import of only one of three nuclear-encoded glutamine tRNAs in Tetrahymena thermophila.
Academic Article RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme.
Academic Article The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena.
Academic Article Selecting apt RNAs for NMR.
Academic Article Kinetic pathway for folding of the Tetrahymena ribozyme revealed by three UV-inducible crosslinks.
Academic Article Joining the two domains of a group I ribozyme to form the catalytic core.
Academic Article Crystal structure of a group I ribozyme domain: principles of RNA packing.
Academic Article RNA tertiary structure mediation by adenosine platforms.
Academic Article Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction.
Academic Article Crystals by design: a strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron.
Academic Article A second catalytic metal ion in group I ribozyme.
Academic Article Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes.
Academic Article Polyadenylation of telomerase RNA in budding yeast.
Academic Article Euplotes telomerase: evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation.
Academic Article An RNA internal loop acts as a hinge to facilitate ribozyme folding and catalysis.
Academic Article Self-assembly of a group I intron active site from its component tertiary structural domains.
Academic Article Identification of ribozymes within a ribozyme library that efficiently cleave a long substrate RNA.
Academic Article Visualization of a tertiary structural domain of the Tetrahymena group I intron by electron microscopy.
Academic Article Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
Academic Article Peptide bond formation by in vitro selected ribozymes.
Academic Article Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis.
Academic Article An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme.
Academic Article A quantitative study of the flexibility contributed to RNA structures by nicks and single-stranded gaps.
Academic Article Reversing time: origin of telomerase.
Academic Article A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
Academic Article Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes.
Academic Article Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.
Academic Article Group I introns: new molecular mechanisms for mRNA repair.
Academic Article A tertiary interaction in the Tetrahymena intron contributes to selection of the 5' splice site.
Academic Article Chromosome end games.
Academic Article Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity.
Academic Article Energetics and cooperativity of tertiary hydrogen bonds in RNA structure.
Academic Article Self-splicing of the group I intron from Anabaena pre-tRNA: requirement for base-pairing of the exons in the anticodon stem.
Academic Article In vitro selection of RNAs with increased tertiary structure stability.
Academic Article Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle.
Academic Article Self-splicing of the Tetrahymena intron from mRNA in mammalian cells.
Academic Article RNA tertiary folding monitored by fluorescence of covalently attached pyrene.
Academic Article Quantifying the energetic interplay of RNA tertiary and secondary structure interactions.
Academic Article Assembly of a ribonucleoprotein catalyst by tertiary structure capture.
Academic Article Multiple folding pathways for the P4-P6 RNA domain.
Academic Article Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Academic Article A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification.
Academic Article Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus.
Academic Article The intervening sequence RNA of Tetrahymena is an enzyme. 1986.
Academic Article Ribozyme recognition of RNA by tertiary interactions with specific ribose 2'-OH groups.
Academic Article Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis.
Academic Article Telomerase and the chromosome end replication problem.
Academic Article The intervening sequence RNA of Tetrahymena is an enzyme.
Academic Article Folding of group I introns from bacteriophage T4 involves internalization of the catalytic core.
Academic Article Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features.
Academic Article The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.
Academic Article A self-splicing group I intron in the nuclear pre-rRNA of the green alga, Ankistrodesmus stipitatus.
Academic Article RNA finds a simpler way.
Academic Article Tetrahymena telomerase is active as a monomer.
Academic Article A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity.
Academic Article Yeast telomerase RNA: a flexible scaffold for protein subunits.
Academic Article Binding of the CBP2 protein to a yeast mitochondrial group I intron requires the catalytic core of the RNA.
Academic Article Localization of transcribed regions on extrachromosomal ribosomal RNA genes of Tetrahymena thermophila by R-loop mapping.
Academic Article RNA editing: world's smallest introns?
Academic Article Alternative secondary structures in the 5' exon affect both forward and reverse self-splicing of the Tetrahymena intervening sequence RNA.
Academic Article Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.
Academic Article Self-splicing and enzymatic activity of an intervening sequence RNA from Tetrahymena.
Academic Article Visualizing the higher order folding of a catalytic RNA molecule.
Academic Article A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro.
Academic Article Atomic level architecture of group I introns revealed.
Academic Article Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom.
Academic Article Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Academic Article Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency.
Academic Article Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: similar reactivity toward single- and double-stranded forms.
Academic Article Local RNA structural changes induced by crystallization are revealed by SHAPE.
Academic Article Self-splicing of group I introns.
Academic Article Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.
Academic Article Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance.
Academic Article Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site.
Academic Article Toward predicting self-splicing and protein-facilitated splicing of group I introns.
Academic Article Crawling out of the RNA world.
Academic Article A natural ribozyme with 3',5' RNA ligase activity.
Academic Article Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor.
Academic Article A model for the RNA-catalyzed replication of RNA.
Academic Article Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by methidiumpropyl.EDTA and localization of the major dye binding sites.
Academic Article Biological catalysis by RNA.
Academic Article The chemistry of self-splicing RNA and RNA enzymes.
Academic Article Ribozymes and their medical implications.
Academic Article RNA as an enzyme.
Academic Article Evolution of biological catalysis: ribozyme to RNP enzyme.
Academic Article How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Academic Article Specificity for 3',5'-linked substrates in RNA-catalyzed RNA polymerization.
Academic Article Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting.
Academic Article Defining the inside and outside of a catalytic RNA molecule.
Academic Article Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants.
Academic Article Aminoacyl esterase activity of the Tetrahymena ribozyme.
Academic Article Structural biology. The ribosome is a ribozyme.
Academic Article Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase.
Academic Article The RNA worlds in context.
Academic Article RNA chemistry. Ribozyme self-replication?
Academic Article Pot1, the putative telomere end-binding protein in fission yeast and humans.
Academic Article A Tetrahymena intron nucleotide connected to the GTP/arginine site.
Academic Article Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova.
Academic Article DNA cleavage catalysed by the ribozyme from Tetrahymena.
Academic Article The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis.
Academic Article Nobel lecture. Self-splicing and enzymatic activity of an intervening sequence RNA from Tetrahymena.
Academic Article Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model.
Academic Article In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron.
Academic Article How a chemist looks at RNA.
Academic Article One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity.
Academic Article Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes.
Academic Article Conserved sequences and structures of group I introns: building an active site for RNA catalysis--a review.
Academic Article Mechanism of recognition of the 5' splice site in self-splicing group I introns.
Academic Article Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena.
Academic Article The Tetrahymena ribozyme acts like an RNA restriction endonuclease.
Academic Article Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor.
Academic Article Yeast telomerase is specialized for C/A-rich RNA templates.
Academic Article Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of Tetrahymena.
Academic Article Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex.
Academic Article Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA.
Academic Article Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences.
Academic Article Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia.
Academic Article In vitro splicing of the ribosomal RNA precursor in nuclei of Tetrahymena.
Academic Article Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA.
Academic Article Telomerase and DNA end replication: no longer a lagging strand problem?
Academic Article Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.
Academic Article Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site.
Academic Article DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.
Academic Article Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing.
Academic Article Ribozymes. Hammerhead nailed down.
Academic Article Beginning to understand the end of the chromosome.
Academic Article Tertiary structure around the guanosine-binding site of the Tetrahymena ribozyme.
Academic Article Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.
Academic Article Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n.
Academic Article Catalytic RNA: structure and mechanism.
Academic Article Metal ion catalysis in the Tetrahymena ribozyme reaction.
Academic Article Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization.
Academic Article Method for determining RNA 3' ends and application to human telomerase RNA.
Academic Article RNA catalysis by a group I ribozyme. Developing a model for transition state stabilization.
Academic Article The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers.
Academic Article X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering.
Academic Article Reverse transcriptase motifs in the catalytic subunit of telomerase.
Academic Article Telomerase catalytic subunit homologs from fission yeast and human.
Academic Article Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity.
Academic Article Telomerase is a true reverse transcriptase. A review.
Academic Article Two modes of survival of fission yeast without telomerase.
Academic Article In vitro selection of the Naegleria GIR1 ribozyme identifies three base changes that dramatically improve activity.
Academic Article Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting.
Academic Article An early transition state for folding of the P4-P6 RNA domain.
Academic Article Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: evidence for product-assisted translocation.
Academic Article Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction.
Academic Article The chemical repertoire of natural ribozymes.
Academic Article The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro.
Academic Article Structure of the Tetrahymena ribozyme: base triple sandwich and metal ion at the active site.
Academic Article Global expression changes resulting from loss of telomeric DNA in fission yeast.
Academic Article RNA as a flexible scaffold for proteins: yeast telomerase and beyond.
Academic Article Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme.
Academic Article Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site.
Academic Article Triple-helix structure in telomerase RNA contributes to catalysis.
Academic Article The generality of self-splicing RNA: relationship to nuclear mRNA splicing.
Academic Article The Tetrahymena intervening sequence ribonucleic acid enzyme is a phosphotransferase and an acid phosphatase.
Academic Article Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence.
Academic Article Guanosine binding required for cyclization of the self-splicing intervening sequence ribonucleic acid from Tetrahymena thermophila.
Academic Article 5' exon requirement for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA and identification of a cryptic 5' splice site in the 3' exon.
Academic Article On the occasion of the 25th anniversary of the discovery of catalytic RNA.
Academic Article Self-splicing and enzymatic cleavage of RNA by a group I intervening sequence.
Academic Article An ultraviolet-inducible adenosine-adenosine cross-link reflects the catalytic structure of the Tetrahymena ribozyme.
Academic Article Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants.
Academic Article Oligomerization of intervening sequence RNA molecules in the absence of proteins.
Academic Article Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by intercalating dyes.
Academic Article Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase.
Academic Article RNA as an enzyme.
Academic Article New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing.
Academic Article RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme.
Academic Article Alteration of substrate specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena ribozyme.
Academic Article Engineering cis-telomerase RNAs that add telomeric repeats to themselves.
Academic Article Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP.
Academic Article Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.
Academic Article A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicing.
Academic Article DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe.
Academic Article The conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing.
Academic Article RNase P branches out from RNP to protein: organelle-triggered diversification?
Academic Article Phylogenetic relationships and altered genome structures among Tetrahymena mitochondrial DNAs.
Academic Article FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.
Academic Article RNA recognition by the DNA end-binding Ku heterodimer.
Academic Article Determinants of the 3' splice site for self-splicing of the Tetrahymena pre-rRNA.
Academic Article Self-splicing RNA and an RNA enzyme in Tetrahymena.
Academic Article Biologic catalysis by RNA.
Academic Article Deletion of nonconserved helices near the 3' end of the rRNA intron of Tetrahymena thermophila alters self-splicing but not core catalytic activity.
Academic Article Structures involved in Tetrahymena rRNA self-splicing and RNA enzyme activity.
Academic Article Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme.
Academic Article Reverse self-splicing of the tetrahymena group I intron: implication for the directionality of splicing and for intron transposition.
Academic Article Coupling of Tetrahymena ribosomal RNA splicing to beta-galactosidase expression in Escherichia coli.
Academic Article Structural conventions for group I introns.
Academic Article Reversibility of cyclization of the Tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice.
Academic Article Intermolecular exon ligation of the rRNA precursor of Tetrahymena: oligonucleotides can function as 5' exons.
Concept Sequence Analysis, RNA
Concept RNA, Ribosomal, 23S
Concept RNA-Binding Protein FUS
Concept RNA, Small Nucleolar
Concept RNA, Transfer
Concept RNA Processing, Post-Transcriptional
Concept RNA
Concept RNA, Small Nuclear
Concept RNA, Small Interfering
Concept RNA, Ribosomal
Concept RNA, Protozoan
Concept RNA Precursors
Concept RNA-Directed DNA Polymerase
Concept RNA Interference
Concept RNA Editing
Concept RNA, Transfer, Met
Concept RNA Caps
Concept RNA, Catalytic
Concept RNA Polymerase II
Concept RNA, Ribosomal, 5S
Concept RNA, Transfer, Ile
Concept RNA, Viral
Concept RNA, Fungal
Concept RNA Splicing
Concept RNA 3' End Processing
Concept RNA Ligase (ATP)
Concept RNA, Archaeal
Concept RNA, Untranslated
Concept RNA, Transfer, Amino Acyl
Concept RNA, Bacterial
Concept RNA Nucleotidyltransferases
Concept DNA-Directed RNA Polymerases
Concept RNA, Transfer, Gln
Concept RNA, Plant
Concept RNA-Binding Proteins
Concept RNA, Transfer, Leu
Concept RNA Stability
Concept RNA, Transfer, Phe
Concept RNA, Messenger
Concept RNA, Double-Stranded
Academic Article Engineering disulfide cross-links in RNA using thiol-disulfide interchange chemistry.
Academic Article 3' terminal diversity of MRP RNA and other human noncoding RNAs revealed by deep sequencing.
Academic Article Promiscuous RNA binding by Polycomb repressive complex 2.
Academic Article RNA seeds higher-order assembly of FUS protein.
Academic Article Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA.
Academic Article The noncoding RNA revolution-trashing old rules to forge new ones.
Academic Article Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT.
Academic Article A dimeric state for PRC2.
Academic Article FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.
Academic Article Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.
Academic Article Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA.
Academic Article Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.
Academic Article RNA World research-still evolving.
Academic Article Biochemical Properties and Biological Functions of FET Proteins.
Academic Article Nucleic acid-binding specificity of human FUS protein.
Academic Article A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.
Academic Article The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.
Academic Article Protein-RNA interaction restricts telomerase from running through the stop sign.
Academic Article Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
Academic Article RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure.
Academic Article Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing.
Academic Article Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines.
Grant NUCLEIC ACID STRUCTURE AND REACTIVITY
Grant TERT Promoter Mutations and Telomerase Reactivation in Cancer Cells
Grant Telomerase and Telomeres: Structure, Function and Regulation
Grant CHROMATIN STRUCTURE OF A TRANSCRIPTION UNIT
Academic Article How do lncRNAs regulate transcription?
Academic Article Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.
Academic Article Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2.
Academic Article In Crystallo Selection to Establish New?RNA?Crystal?Contacts.
Academic Article Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA.
Concept RNA, Small Untranslated
Concept RNA Cleavage
Concept RNA, Long Noncoding
Academic Article C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms.
Academic Article Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines.
Academic Article Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers.
Academic Article RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells.
Academic Article Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention.
Academic Article RNA in biological condensates.
Academic Article DNMT1 inhibition by pUG-fold quadruplex RNA.
Academic Article Structural basis for inactivation of PRC2 by G-quadruplex RNA.
Academic Article Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search.
Academic Article PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers.
Academic Article Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells.
Academic Article Structural basis for inactivation of PRC2 by G-quadruplex RNA.
Academic Article Dissecting telomerase RNA structural heterogeneity in living human cells with DMS-MaPseq.

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