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Search Results to Aaron W. Michels

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Michels, Aaron

One or more keywords matched the following items that are connected to Michels, Aaron

Item Type	Name
Academic Article	The anti-insulin trimolecular complex in type 1 diabetes.
Academic Article	Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.
Academic Article	Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice.
Academic Article	Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial.
Academic Article	2011 Update: antigen-specific therapy in type 1 diabetes.
Academic Article	Immune intervention in type 1 diabetes.
Academic Article	Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation.
Academic Article	Targeting the trimolecular complex: the pathway towards type 1 diabetes prevention.
Concept	Diabetes Mellitus, Type 1
Concept	Diabetes Mellitus, Type 2
Academic Article	Severe hypoglycemia and diabetic ketoacidosis in adults with type 1 diabetes: results from the T1D Exchange clinic registry.
Academic Article	Type 1 diabetes.
Academic Article	Use of non-insulin therapies for type 1 diabetes.
Academic Article	Targeting the trimolecular complex.
Academic Article	Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.
Academic Article	Chromogranin A is a T cell antigen in human type 1 diabetes.
Academic Article	?d T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation.
Academic Article	a1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1? responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.
Academic Article	Lessons from type 1 diabetes for understanding natural history and prevention of autoimmune disease.
Academic Article	Anti-thymocyte globulin/G-CSF treatment preserves ? cell function in patients with established type 1 diabetes.
Academic Article	Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.
Academic Article	Type 1 diabetes: A predictable disease.
Academic Article	New approaches for predicting T cell-mediated drug reactions: A role for inducible and potentially preventable autoimmunity.
Academic Article	Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at prevention.
Academic Article	Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes.
Academic Article	A multiplex assay combining insulin, GAD, IA-2 and transglutaminase autoantibodies to facilitate screening for pre-type 1 diabetes and celiac disease.
Academic Article	Validation of a rapid type 1 diabetes autoantibody screening assay for community-based screening of organ donors to identify subjects at increased risk for the disease.
Academic Article	Immune Intervention and Preservation of Pancreatic Beta Cell Function in Type 1 Diabetes.
Academic Article	Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects?
Academic Article	Islet Autoantibody Measurements from Dried Blood Spots on Filter Paper Strongly Correlate to Serum Levels.
Academic Article	Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes.
Academic Article	Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
Academic Article	Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development.
Academic Article	Increased inflammation is associated with islet autoimmunity and type 1 diabetes in the Diabetes Autoimmunity Study in the Young (DAISY).
Grant	Autoantigens targeted by CD8 T cells in type 1 diabetes: from islets to blood
Grant	Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes
Grant	Small Molecules Targeting Allele Specific MHC Class II Presentation
Grant	Insulin Specific T and B cells in Type 1 Diabetes
Academic Article	Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.
Academic Article	Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the "Scene of the Crime".
Grant	Insulin Specific T Cell Response Shaped by Diabetes Protective MHC Class II Molecules
Academic Article	TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes.
Academic Article	Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes.
Academic Article	Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.
Academic Article	? Cell replacement: improving on the design.
Academic Article	Learning From Past Failures of Oral Insulin Trials.
Academic Article	PD-1 Inhibitor Immune-Related Adverse Events in Patients With Preexisting Endocrine Autoimmunity.
Academic Article	Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes.
Academic Article	Rationally designed small molecules to prevent type 1 diabetes.
Academic Article	Determining Antigen Specificity of Human Islet Infiltrating T Cells in Type 1 Diabetes.
Academic Article	A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen.
Academic Article	Autoantibodies Directed Toward a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes.
Academic Article	Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes.
Academic Article	Immune checkpoint inhibitor-induced Type 1 diabetes: a systematic review and meta-analysis.
Academic Article	Screening children for type 1 diabetes-associated antibodies at community health fairs.
Academic Article	High-throughput multiplexed autoantibody detection to screen type 1 diabetes and multiple autoimmune diseases simultaneously.
Grant	Autoantigens targeted by CD8 T cells in type 1 diabetes: from islets to blood
Academic Article	Immune Checkpoint Inhibitor-Induced Type 1 Diabetes: An Underestimated Risk.
Academic Article	Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02.
Academic Article	Adverse events associated with immune checkpoint inhibitors: a new era in autoimmune diabetes.
Academic Article	Advances in Diabetes Treatment - Once-Weekly Insulin.
Academic Article	Is It Time to Screen the General Population for Type 1 Diabetes?
Academic Article	T-cell responses to hybrid insulin peptides prior to type 1 diabetes development.
Academic Article	Prevalence of SARS-CoV-2 Antibodies in Children and Adults with Type 1 Diabetes.
Academic Article	Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors.
Academic Article	Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
Academic Article	Using the T Cell Receptor as a Biomarker in Type 1 Diabetes.
Academic Article	The pathogenesis, natural history, and treatment of type 1 diabetes: time (thankfully) does not stand still.
Academic Article	Self-Antigens Targeted by Regulatory T Cells in Type 1 Diabetes.
Academic Article	Temporal development of T cell receptor repertoires during childhood in health and disease.
Academic Article	Stem-Cell-Derived ?-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity.
Academic Article	Similar Time Course of Humoral Response to SARS-CoV-2 mRNA Vaccines in People With and Without Type 1 Diabetes.
Academic Article	Identification of Autoantibodies to a Hybrid Insulin Peptide in Type 1 Diabetes.
Academic Article	Tracking DNA-based antigen-specific T cell receptors during progression to type 1 diabetes.
Academic Article	Routine Blood Glucose Monitoring Does Not Predict Onset of Immune Checkpoint Inhibitor-Induced Type 1 Diabetes.

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