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Search Results to Charles A Dinarello

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Dinarello, Charles

One or more keywords matched the following items that are connected to Dinarello, Charles

Item Type	Name
Academic Article	Induction of circulating IL-1 receptor antagonist by IFN treatment.
Academic Article	Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells.
Academic Article	Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice.
Academic Article	IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family.
Academic Article	Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article	Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures.
Academic Article	Interleukin-18.
Academic Article	IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.
Academic Article	IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor.
Academic Article	Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia.
Academic Article	Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain.
Academic Article	Role of interferon regulatory factor-1 in the regulation of IL-18 production and activity.
Academic Article	Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells.
Academic Article	Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18.
Academic Article	Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production.
Academic Article	Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants.
Academic Article	Role of interleukin-18 in host defense against disseminated Candida albicans infection.
Academic Article	Rat interleukin-18 binding protein: cloning, expression, and characterization.
Academic Article	Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.
Academic Article	Interleukin-18 and host defense against infection.
Academic Article	Anti-cytokine therapeutics and infections.
Academic Article	Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release.
Academic Article	Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein.
Academic Article	Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF-alpha, IFN-gamma and glucocorticoids.
Academic Article	IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response.
Academic Article	Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article	Effect of a four-week course of interleukin-10 on cytokine production in a placebo-controlled study of HIV-1-infected subjects.
Academic Article	Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level.
Academic Article	Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice.
Academic Article	The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
Academic Article	Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis.
Academic Article	The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ? cells in vivo and in vitro.
Academic Article	A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures.
Academic Article	Induction by IL 1 and interferon-?: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254.
Academic Article	IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.
Academic Article	Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis.
Academic Article	The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
Academic Article	IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.
Academic Article	Membrane interleukin-18 revisits membrane IL-1a in T-helper type 1 responses.
Academic Article	The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses.
Academic Article	Lymphokines and bile secretion in the rat.
Academic Article	Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans.
Academic Article	Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
Academic Article	Chemical characterization of an interleukin-1-inducing substance derived from human mixed leukocyte reactions: IL-1-inducing substance is not gamma interferon.
Academic Article	Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans.
Academic Article	IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma.
Academic Article	Restoration of anti-interleukin-1 depressed natural killer activity by human recombinant interferon alpha or gamma, human recombinant interleukin-2 and indomethacin.
Academic Article	A switch to high-flux helixone membranes reverses suppressed interferon-gamma production in patients on low-flux dialysis.
Academic Article	IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease.
Academic Article	Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure.
Academic Article	Clinical, hematologic, and immunologic effects of interleukin-10 in humans.
Academic Article	Overview of interleukin-18: more than an interferon-gamma inducing factor.
Academic Article	Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Academic Article	Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Academic Article	IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
Academic Article	An IFN-gamma-independent proinflammatory role of IL-18 in murine streptococcal cell wall arthritis.
Academic Article	Differential roles of interleukin-18 (IL-18) and IL12 for induction of gamma interferon by staphylococcal cell wall components and superantigens.
Academic Article	Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels.
Academic Article	The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures.
Academic Article	Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure.
Academic Article	Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
Academic Article	Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha.
Academic Article	Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.
Academic Article	The effect of whole body hyperthermia on the immune cell activity of cancer patients.
Academic Article	Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits.
Academic Article	Low-flux hemodialysis suppresses interferon-gamma production: the possible role of beta2-microglobulin.
Academic Article	Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.
Academic Article	Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
Academic Article	Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).
Academic Article	The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1?.
Academic Article	The lysine deacetylase inhibitor Givinostat inhibits ?-cell IL-1? induced IL-1? transcription and processing.
Academic Article	Release of lymphokines after infection with Epstein Barr virus in vitro. II. A monocyte-dependent inhibitor of interleukin 1 downregulates the production of interleukin 2 and interferon-gamma in rheumatoid arthritis.
Academic Article	Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes.
Academic Article	C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma.
Academic Article	The effect of interleukin 1 on IgG synthesis in systemic lupus erythematosus.
Academic Article	Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
Academic Article	Detection of circulating tumor necrosis factor after endotoxin administration.
Concept	Interferon-gamma
Academic Article	Towards a role of interleukin-32 in atherosclerosis.
Academic Article	IL-32 promotes angiogenesis.
Academic Article	Interleukin-18, more than a Th1 cytokine.
Academic Article	Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.
Academic Article	Blocking IL-1? reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
Academic Article	A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.

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Interferon gamma