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Search Results to Lori Gail Sussel

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Sussel, Lori

One or more keywords matched the following items that are connected to Sussel, Lori

Item Type	Name
Academic Article	Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.
Academic Article	The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration.
Academic Article	Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine.
Academic Article	Pancreatic beta cells require NeuroD to achieve and maintain functional maturity.
Concept	Paired Box Transcription Factors
Concept	Basic Helix-Loop-Helix Transcription Factors
Concept	Forkhead Transcription Factors
Concept	GATA6 Transcription Factor
Concept	Transcription Factors
Concept	Transcription Factor Brn-3A
Concept	Otx Transcription Factors
Concept	GATA4 Transcription Factor
Concept	Transcription, Genetic
Concept	Maf Transcription Factors, Large
Academic Article	A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.
Academic Article	Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.
Academic Article	Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae.
Academic Article	Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure.
Academic Article	Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development.
Academic Article	Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells.
Academic Article	Beta-cell transcription factors and diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese.
Academic Article	Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling.
Academic Article	Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.
Academic Article	Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.
Academic Article	Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.
Academic Article	The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation.
Academic Article	Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development.
Academic Article	FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.
Academic Article	Gata6 is an important regulator of mouse pancreas development.
Academic Article	Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.
Academic Article	Nkx2.2 regulates beta-cell function in the mature islet.
Academic Article	Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells.
Academic Article	Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine.
Academic Article	Ghrelin is dispensable for embryonic pancreatic islet development and differentiation.
Academic Article	Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.
Academic Article	GABAergic differentiation induced by Mash1 is compromised by the bHLH proteins Neurogenin2, NeuroD1, and NeuroD2.
Academic Article	Nkx2.2 activates the ghrelin promoter in pancreatic islet cells.
Academic Article	Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development.
Academic Article	Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.
Academic Article	A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning.
Academic Article	Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas.
Academic Article	Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression.
Academic Article	Nkx2.2 repressor complex regulates islet ?-cell specification and prevents ?-to-a-cell reprogramming.
Academic Article	Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology.
Academic Article	Pancreatic ? cell dedifferentiation as a mechanism of diabetic ? cell failure.
Academic Article	Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.
Academic Article	Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population.
Academic Article	Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas.
Academic Article	A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.
Academic Article	Generation of mice encoding a conditional allele of Nkx2.2.
Academic Article	Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas.
Academic Article	Nkx2.2:Cre knock-in mouse line: a novel tool for pancreas- and CNS-specific gene deletion.
Academic Article	Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS.
Academic Article	Mammalian Nkx2.2+ perineurial glia are essential for motor nerve development.
Academic Article	The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1.
Academic Article	Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential.
Academic Article	Unique functions of Gata4 in mouse liver induction and heart development.
Academic Article	GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.
Academic Article	?linc1 encodes a long noncoding RNA that regulates islet ?-cell formation and function.
Academic Article	The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2.
Academic Article	Pancreatic ? cell identity requires continual repression of non-? cell programs.
Academic Article	LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ? cells.
Academic Article	Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development.
Grant	The role of Gata 4 in exocrine pancreas development
Grant	Regulation of exocrine pancreas formation
Grant	Transcriptional regulation of exocrine development
Grant	Defining the roles of Nkx2.2 and NeuroD in regulating islet cell fate
Grant	Nkx2.2 and Gata6: regulation of islet development
Grant	GENETIC ANALYSIS OF MOUSE NKX-21 AND NKX-22 GENES
Grant	Long non-coding RNAs in Islet Cell Biology
Academic Article	Gotta Have GATA for Human Pancreas Development.
Grant	Intersection of signaling pathways and transcription factors regulating islet development
Academic Article	Long Non-coding RNAs as Local Regulators of Pancreatic Islet Transcription Factor Genes.
Concept	PAX6 Transcription Factor
Academic Article	Murine Perinatal ?-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1.
Academic Article	The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function.
Academic Article	Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human ? cell specification.
Academic Article	Groucho co-repressor proteins regulate ? cell development and proliferation by repressing Foxa1 in the developing mouse pancreas.
Academic Article	Single Molecule-Based fliFISH Validates Radial and Heterogeneous Gene Expression Patterns in Pancreatic Islet ?-Cells.
Academic Article	Major ? cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.

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