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Search Results to David H Wagner Jr.

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Wagner, David

One or more keywords matched the following items that are connected to Wagner, David

Item Type	Name
Academic Article	Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.
Academic Article	Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.
Academic Article	Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery.
Academic Article	High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity.
Academic Article	Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.
Academic Article	CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity.
Academic Article	CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.
Academic Article	CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance.
Academic Article	Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity.
Concept	Mice, Inbred NOD
Academic Article	An alternative role for Foxp3 as an effector T cell regulator controlled through CD40.
Academic Article	CD40 interacts directly with RAG1 and RAG2 in autoaggressive T cells and Fas prevents CD40-induced RAG expression.
Academic Article	A CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice.
Grant	CD40-Induced TCR Revision: A Mechanism for Autoimmunity
Grant	A unique approach to control the CD40/CD154 inflammatory axis in type 1 diabetes
Academic Article	CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes.
Grant	Developing a Small Peptide to Control Autoimmune Inflammation In Type 1 Diabetes
Academic Article	CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor. Reply to Pagni PP, Wolf A, Lo Conte M et al [letter].
Grant	Developing a small peptide to control autoimmune inflammation in type 1 diabetes

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Mice Inbred NOD