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Search Results to Wells Alton Messersmith

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Messersmith, Wells

One or more keywords matched the following items that are connected to Messersmith, Wells

Item Type	Name
Academic Article	An in vivo platform for translational drug development in pancreatic cancer.
Academic Article	Chemotherapy and regional therapy of hepatic colorectal metastases: expert consensus statement.
Academic Article	Panitumumab, a monoclonal anti epidermal growth factor receptor antibody in colorectal cancer: another one or the one?
Academic Article	Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer.
Academic Article	Targeting EGFR in colorectal cancer.
Academic Article	Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors.
Academic Article	Antitumor effects and biomarkers of activity of AZD0530, a Src inhibitor, in pancreatic cancer.
Academic Article	Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer.
Academic Article	Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.
Academic Article	Phase I safety, pharmacokinetic, and pharmacodynamic study of ENMD-2076, a novel angiogenic and Aurora kinase inhibitor, in patients with advanced solid tumors.
Academic Article	Current status of SRC inhibitors in solid tumor malignancies.
Academic Article	Promising targets and drugs in development for colorectal cancer.
Academic Article	Longitudinal assessment of oxaliplatin-induced neuropathy.
Academic Article	Development of novel targeted agents in the treatment of metastatic colorectal cancer.
Academic Article	Phase I study of bosutinib, a src/abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors.
Academic Article	The development of regorafenib and its current and potential future role in cancer therapy.
Academic Article	Recent advances in the pharmacological treatment of colorectal cancer.
Academic Article	Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours.
Academic Article	Novel targets in solid tumors: MEK inhibitors.
Academic Article	Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors.
Academic Article	No time to waste: decreasing patient wait times for chemotherapy administration using automated prioritization in an oncology pharmacy system.
Academic Article	KRAS mutations and susceptibility to cetuximab and panitumumab in colorectal cancer.
Academic Article	Myeloid growth factors. Clinical practice guidelines in oncology.
Academic Article	A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.
Academic Article	Phase I study of MGCD0103 given as a three-times-per-week oral dose in patients with advanced solid tumors.
Academic Article	Novel agents in the treatment of metastatic colorectal cancer.
Academic Article	New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways.
Academic Article	Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.
Academic Article	Patient-derived tumour xenografts as models for oncology drug development.
Academic Article	Biomarker-driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer.
Academic Article	A phase I study of sorafenib and vorinostat in patients with advanced solid tumors with expanded cohorts in renal cell carcinoma and non-small cell lung cancer.
Academic Article	Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial.
Academic Article	Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial.
Concept	Antineoplastic Agents
Concept	Antineoplastic Agents, Phytogenic
Academic Article	Phase I study of oral rigosertib (ON 01910.Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignancies.
Academic Article	Colon cancer, version 3.2014.
Academic Article	A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma.
Academic Article	An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIa and potent anticancer agent.
Academic Article	Panitumumab in the treatment of colon cancer: A biomarker dilemma.
Academic Article	Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
Academic Article	A phase I study of PF-04449913, an oral hedgehog inhibitor, in patients with advanced solid tumors.
Academic Article	A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Academic Article	Targeting the WNT Signaling Pathway in Cancer Therapeutics.
Academic Article	Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Academic Article	The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.
Academic Article	Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.
Academic Article	Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody-Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies.
Academic Article	Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies.
Academic Article	Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Academic Article	Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C.
Academic Article	Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.
Academic Article	Systemic Management of Colorectal Cancer.
Academic Article	A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.
Academic Article	Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics.
Academic Article	Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.
Academic Article	Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
Academic Article	A phase 1, dose-escalation study of PF-06664178, an anti-Trop-2/Aur0101 antibody-drug conjugate in patients with advanced or metastatic solid tumors.
Academic Article	Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer.
Academic Article	Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.
Academic Article	Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models.
Academic Article	Antibody drug conjugates under investigation in phase I and phase II clinical trials for gastrointestinal cancer.
Academic Article	Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.
Concept	Antineoplastic Agents, Immunological
Academic Article	Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.
Academic Article	Sacituzumab govitecan: breakthrough targeted therapy for triple-negative breast cancer.
Academic Article	Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment.
Academic Article	First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer.
Academic Article	Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study.
Academic Article	Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L.

Search Criteria

Antineoplastic Agents