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Search Results to Michael John Zuscik

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Zuscik, Michael

One or more keywords matched the following items that are connected to Zuscik, Michael

Item Type	Name
Concept	Chondrocytes
Academic Article	Characterization of voltage-sensitive calcium channels in growth plate chondrocytes.
Academic Article	TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages.
Academic Article	Growth plate chondrocyte maturation is regulated by basal intracellular calcium.
Academic Article	PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling.
Academic Article	Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation.
Academic Article	Beta-catenin, cartilage, and osteoarthritis.
Academic Article	ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation.
Academic Article	Smad6 is induced by BMP-2 and modulates chondrocyte differentiation.
Academic Article	Environmental agents affect skeletal growth and development.
Academic Article	ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.
Academic Article	Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction.
Academic Article	Lead alters parathyroid hormone-related peptide and transforming growth factor-beta1 effects and AP-1 and NF-kappaB signaling in chondrocytes.
Academic Article	Activation of phosphoinositide metabolism by parathyroid hormone in growth plate chondrocytes.
Academic Article	Cyclic-AMP-dependent protein kinase activity is not required by parathyroid hormone to stimulate phosphoinositide signaling in chondrocytes but is required to transduce the hormone's proliferative effect.
Academic Article	Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis.
Academic Article	Differential regulation of EP receptor isoforms during chondrogenesis and chondrocyte maturation.
Academic Article	Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes.
Academic Article	CCN1 Regulates Chondrocyte Maturation and Cartilage Development.
Academic Article	Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage.
Academic Article	Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes.
Academic Article	Cytosolic free calcium concentrations in avian growth plate chondrocytes.
Academic Article	Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice.
Academic Article	Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene.
Academic Article	Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.
Academic Article	CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter.
Academic Article	Notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance.
Academic Article	Impaired angiogenesis during fracture healing in GPCR kinase 2 interacting protein-1 (GIT1) knock out mice.
Academic Article	Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis.
Academic Article	Cartilage-specific RBPj?-dependent and -independent Notch signals regulate cartilage and bone development.
Academic Article	Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2.
Academic Article	Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta.
Academic Article	Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5.
Academic Article	Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation.
Academic Article	Ski inhibits TGF-?/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes.
Academic Article	5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.
Academic Article	Axin1 and Axin2 are regulated by TGF- and mediate cross-talk between TGF- and Wnt signaling pathways.
Academic Article	Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-? signaling.
Academic Article	Regulation of embryonic endochondral ossification by Smurf2.
Academic Article	Transforming growth factor-beta1 induced alteration of skeletal morphogenesis in vivo.
Academic Article	Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation.
Academic Article	Engineering superficial zone features in tissue engineered cartilage.
Academic Article	Regulation of chondrogenesis and chondrocyte differentiation by stress.
Academic Article	Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway.
Academic Article	Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.
Academic Article	Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.
Academic Article	Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9.
Grant	Mechanism of Nicotine Action in the Healing Skeleton
Academic Article	Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.
Academic Article	Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis.
Academic Article	IKK?-NF-?B signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice.

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Chondrocytes