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A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.
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has major subject area list
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Ataxia Telangiectasia Mutated Proteins; Corpus Striatum; Huntington Disease; Manganese; Neural Stem Cells; Tumor Suppressor Protein p53
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has minor subject area list
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Amino Acid Motifs; Animals; Cell Line; Disease Models, Animal; DNA Damage; Female; Humans; Male; Mice; Phosphorylation; Signal Transduction
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information resource reference
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Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Hum Mol Genet. 2015 Apr 01; 24(7):1929-44.
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label
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A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.
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