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Search Results to Christopher H Lieu

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Lieu, Christopher

One or more keywords matched the following items that are connected to Lieu, Christopher

Item Type	Name
Academic Article	A dose-ranging study of the pharmacokinetics and pharmacodynamics of the selective apoptotic antineoplastic drug (SAAND), OSI-461, in patients with advanced cancer, in the fasted and fed state.
Academic Article	A phase I study of bortezomib, etoposide and carboplatin in patients with advanced solid tumors refractory to standard therapy.
Academic Article	Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis.
Academic Article	Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance.
Academic Article	Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer.
Academic Article	The SRC family of protein tyrosine kinases: a new and promising target for colorectal cancer therapy.
Concept	Colorectal Neoplasms, Hereditary Nonpolyposis
Concept	Biliary Tract Neoplasms
Concept	Early Detection of Cancer
Concept	Digestive System Neoplasms
Concept	Neoplasms, Multiple Primary
Concept	Esophageal Neoplasms
Concept	Brain Neoplasms
Concept	Lung Neoplasms
Concept	Rectal Neoplasms
Concept	Adrenal Gland Neoplasms
Concept	Appendiceal Neoplasms
Concept	Ovarian Neoplasms
Concept	Colorectal Neoplasms
Concept	Pancreatic Neoplasms
Concept	Breast Neoplasms
Concept	Stomach Neoplasms
Concept	Neoplasms
Concept	National Cancer Institute (U.S.)
Concept	Colonic Neoplasms
Concept	Gastrointestinal Neoplasms
Concept	Intestinal Neoplasms
Concept	Liver Neoplasms
Academic Article	From bench to bedside: lessons learned in translating preclinical studies in cancer drug development.
Academic Article	The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer.
Academic Article	Systemic chemotherapy and surgical cytoreduction for poorly differentiated and signet ring cell adenocarcinomas of the appendix.
Academic Article	Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program.
Academic Article	A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
Academic Article	Targeting the WNT Signaling Pathway in Cancer Therapeutics.
Academic Article	Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Academic Article	Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers.
Academic Article	Phase I Study of DMOT4039A, an Antibody-Drug Conjugate Targeting Mesothelin, in Patients with Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer.
Academic Article	Therapeutic Approaches to RAS Mutation.
Academic Article	The Multidisciplinary Approach to GI Cancer Results in Change of Diagnosis and Management of Patients. Multidisciplinary Care Impacts Diagnosis and Management of Patients.
Academic Article	Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer.
Academic Article	Molecular Biomarkers for the Evaluation of Colorectal Cancer.
Academic Article	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.
Academic Article	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology.
Academic Article	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.
Academic Article	Impact of neoadjuvant chemoradiation on perioperative outcomes in patients with rectal cancer.
Academic Article	Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline Summary From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.
Grant	The Development of Novel Targeted Therapy for KRAS Mutant Colorectal Cancer
Academic Article	Adjuvant radiotherapy improves overall survival in patients with resected gastric adenocarcinoma: A National Cancer Data Base analysis.
Academic Article	A Phase Ib Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Cobimetinib and Duligotuzumab in Patients with Previously Treated Locally Advanced or Metastatic Cancers with Mutant KRAS.
Academic Article	Patterns of Care for Locally Advanced Pancreatic Adenocarcinoma Using the National Cancer Database.
Academic Article	Cetuximab or Bevacizumab With First-Line Chemotherapy in Advanced KRAS Wild-Type Colorectal Cancer: No Difference, but Not the Same.
Academic Article	Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.
Academic Article	Reply to Tumor localization may change the type of adjuvant treatment in gastric cancer.
Academic Article	A Blueprint to Advance Colorectal Cancer Immunotherapies.
Academic Article	NCCN Guidelines Insights: Neuroendocrine and Adrenal Tumors, Version 2.2018.
Academic Article	Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group.
Academic Article	Addressing Survivorship in Cancer Care.
Academic Article	Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.
Academic Article	A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.
Academic Article	Association of Cancer Immunotherapy With Acute Macular Neuroretinopathy and Diffuse Retinal Venulitis.
Academic Article	Is Precision Medicine an Oxymoron?
Grant	Utilizing MEK Inhibition to Sensitize Microsatellite Stable Colorectal Cancer to Immune Checkpoint Therapy
Academic Article	Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.
Concept	Cancer Survivors
Concept	Triple Negative Breast Neoplasms
Academic Article	Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer: ASCO Clinical Practice Guideline.
Academic Article	A Summary of the Fight Colorectal Cancer Working Meeting: Exploring Risk Factors and Etiology of Sporadic Early-Age Onset Colorectal Cancer.
Academic Article	Integrating Biomarkers and Targeted Therapy Into Colorectal Cancer Management.
Academic Article	Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer.
Academic Article	Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients.
Academic Article	Early-Onset Appendiceal Cancer Survival by Race or Ethnicity in the United States.
Academic Article	ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper.
Academic Article	Safety and Clinical Activity of Atezolizumab Plus Bevacizumab in Patients with Ovarian Cancer: A Phase Ib Study.
Academic Article	Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406).
Academic Article	Community Health Behaviors and Geographic Variation in Early-Onset Colorectal Cancer Survival Among Women.
Academic Article	Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers.
Academic Article	Gut instinct: a call to study the biology of early-onset colorectal cancer disparities.
Academic Article	Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.
Academic Article	The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry.
Academic Article	Characteristics of Early-Onset vs Late-Onset Colorectal Cancer: A Review.
Academic Article	Early age onset colorectal cancer.
Academic Article	Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study.
Academic Article	Neuroendocrine and Adrenal Tumors, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	Adjuvant Therapy for Stage II Colon Cancer: ASCO Guideline Update.
Academic Article	Rectal Cancer: Clinical and Molecular Predictors of a Complete Response to Total Neoadjuvant Therapy.
Academic Article	Case of Metastatic Pheochromocytoma and Meningiomas in a Patient With Lynch Syndrome.
Academic Article	The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Academic Article	A comprehensive framework for early-onset colorectal cancer research.
Academic Article	Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion.
Academic Article	Comparison of trends in early-onset colorectal cancer in North America and Europe - Authors' reply.
Academic Article	Early-Age-Onset Colorectal Cancer in Canada: Evidence, Issues and Calls to Action.
Academic Article	Current status and future of targeted peptide receptor radionuclide positron emission tomography imaging and therapy of gastroenteropancreatic-neuroendocrine tumors.
Academic Article	ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.
Academic Article	Informational Needs of Surgical Oncology Patients: A Cross-Sectional Patient Survey.
Academic Article	Minimal Residual Disease-Directed Adjuvant Therapy for Patients With Early-Stage Colon Cancer: CIRCULATE-US.
Academic Article	Treatment of Metastatic Colorectal Cancer: ASCO Guideline.
Academic Article	Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models.
Academic Article	The use of immunotherapy in metastatic microsatellite-stable colorectal cancer.
Academic Article	Improved Survival After Adjuvant Therapy in Locally Advanced Rectal Cancer Patients With Pathologic Complete Response.
Academic Article	Phase 1 study of the safety, pharmacokinetics, and preliminary efficacy of CA102N as monotherapy and in combination with trifluridine-tipiracil in patients with locally advanced or metastatic solid tumors.
Academic Article	Anti-EGFR Therapy for Left-Sided RAS Wild-type Colorectal Cancer-PARADIGM Shift.
Academic Article	Podcast article: Biomarker testing in colorectal cancer.
Academic Article	Pulmonary metastasectomy is associated with survival after lung-only recurrence in pancreatic cancer.
Academic Article	Early-Onset GI Cancers: Rising Trends, Genetic Risks, Novel Strategies, and Special Considerations.
Academic Article	The Local Microbiome in Esophageal Cancer and Treatment Response: A Review of Emerging Data and Future Directions.
Academic Article	Biomarker Testing Trends in Patients With Metastatic Colorectal Cancer Who Live in Rural Areas and Urban Clusters in the US.
Academic Article	Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Academic Article	First-in-Human Dose-Escalation Study of the Novel Oral Depsipeptide Class I-Targeting HDAC Inhibitor Bocodepsin (OKI-179) in Patients with Advanced Solid Tumors.

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Cancer