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A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease.
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has major subject area list
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Huntington Disease; Immunoglobulin Variable Region; Lymphokines; Nerve Tissue Proteins; Nuclear Proteins; Sialoglycoproteins
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has minor subject area list
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Animals; Animals, Newborn; Biolistics; Cell Aggregation; Cell Count; Cell Death; Corpus Striatum; Culture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Huntingtin Protein; Luminescent Proteins; Malonates; Mice; Mice, Inbred BALB C; Mutation; Peptides; Propidium; Time Factors; Transfection
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information resource reference
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Murphy RC, Messer A. A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease. Brain Res Mol Brain Res. 2004 Feb 05; 121(1-2):141-5.
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label
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A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease.
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