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keywords Precision medicine
overview I am an academic general internist and clinician-investigator focused on precision medicine applied to the prevention and treatment of obesity, diabetes, and their complications, particularly cardiovascular disease. I use precision medicine broadly to mean: 1. Defining and understanding subgroups and heterogeneity in the diverse population of individuals with cardiometabolic disease. 2. Evaluating the implications of those subgroups/heterogeneity for diabetes prevention and management. 3. Determining how well subgroups with different cardiometabolic disease characteristics or treatment response defined in one study population generalize to other study populations. With those goals in mind, we use electronic health record data and genetic data as tools to understand the heterogeneity of the diabetes patient population and variability in response to interventions, to identify novel risk factors for cardiometabolic diseases, and to build risk models optimized to real-world patient populations in health systems. Our ultimate goal is to build evidence that guides individualized targeting of preventive and treatment interventions for obesity, diabetes, and diabetes complications. In addition to my research, I work clinically as a hospitalist at the Rocky Mountain Regional VA Medical Center.

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