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Structure-guided design and development of cyclic peptide allosteric activators of Polycomb Repressive Complex 2.

Tokodai Y, Matyas M, Ishigamori A, O'Connor E, Zhang A, Yamazaki S, Hiraki T, Lohar N, Yao L, Stoner R, Paez-Beltran LE, Kanamitsu K, Nakaya N, Ichikawa S, Brumbaugh J, Kasinath V, Yakushiji F. Structure-guided design and development of cyclic peptide allosteric activators of Polycomb Repressive Complex 2. bioRxiv. 2025 Jun 26.

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