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Connection

Ram Nagaraj to Crystallins

This is a "connection" page, showing publications Ram Nagaraj has written about Crystallins.

 
Connection Strength
 
 
 
7.754
 
  1. Panja S, Rankenberg J, Michel C, Cooksley G, Glomb MA, Nagaraj RH. Proximal cysteine residues in proteins promote Ne-carboxyalkylation of lysine residues by a-dicarbonyl compounds. J Biol Chem. 2025 Apr; 301(4):108377.
    View in: PubMed
    Score: 0.905
  2. Panja S, Nahomi RB, Rankenberg J, Michel CR, Gaikwad H, Nam MH, Nagaraj RH. Aggrelyte-2 promotes protein solubility and decreases lens stiffness through lysine acetylation and disulfide reduction: Implications for treating presbyopia. Aging Cell. 2023 04; 22(4):e13797.
    View in: PubMed
    Score: 0.787
  3. Nahomi RB, Nandi SK, Rakete S, Michel C, Fritz KS, Nagaraj RH. Lysine malonylation and propionylation are prevalent in human lens proteins. Exp Eye Res. 2020 01; 190:107864.
    View in: PubMed
    Score: 0.625
  4. Nam MH, Nagaraj RH. Matrix-bound AGEs enhance TGF?2-mediated mesenchymal transition of lens epithelial cells via the noncanonical pathway: implications for secondary cataract formation. Biochem J. 2018 04 23; 475(8):1427-1440.
    View in: PubMed
    Score: 0.562
  5. Nahomi RB, Pantcheva MB, Nagaraj RH. aB-crystallin is essential for the TGF-?2-mediated epithelial to mesenchymal transition of lens epithelial cells. Biochem J. 2016 05 15; 473(10):1455-69.
    View in: PubMed
    Score: 0.486
  6. Linetsky M, Raghavan CT, Johar K, Fan X, Monnier VM, Vasavada AR, Nagaraj RH. UVA light-excited kynurenines oxidize ascorbate and modify lens proteins through the formation of advanced glycation end products: implications for human lens aging and cataract formation. J Biol Chem. 2014 Jun 13; 289(24):17111-23.
    View in: PubMed
    Score: 0.427
  7. Nahomi RB, Huang R, Nandi SK, Wang B, Padmanabha S, Santhoshkumar P, Filipek S, Biswas A, Nagaraj RH. Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human aB-crystallin. Biochemistry. 2013 Nov 12; 52(45):8126-38.
    View in: PubMed
    Score: 0.412
  8. Linetsky M, Kaid Johar SR, Meltretter J, Padmanabha S, Parmar T, Vasavada AR, Pischetsrieder M, Nagaraj RH. Determination of dideoxyosone precursors of AGEs in human lens proteins. Arch Biochem Biophys. 2011 Oct; 514(1-2):16-26.
    View in: PubMed
    Score: 0.353
  9. Mailankot M, Howell S, Nagaraj RH. Kynurenine inhibits fibroblast growth factor 2-mediated expression of crystallins and MIP26 in lens epithelial cells. Biochim Biophys Acta. 2010 Jul-Aug; 1802(7-8):609-20.
    View in: PubMed
    Score: 0.324
  10. Gangadhariah MH, Wang B, Linetsky M, Henning C, Spanneberg R, Glomb MA, Nagaraj RH. Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability. Biochim Biophys Acta. 2010 Apr; 1802(4):432-41.
    View in: PubMed
    Score: 0.317
  11. Pasupuleti N, Matsuyama S, Voss O, Doseff AI, Song K, Danielpour D, Nagaraj RH. The anti-apoptotic function of human aA-crystallin is directly related to its chaperone activity. Cell Death Dis. 2010; 1:e31.
    View in: PubMed
    Score: 0.316
  12. Nagaraj RH, Padmanabha S, Mailankot M, Staniszewska M, Mun LJ, Glomb MA, Linetsky MD. Modulation of advanced glycation endproduct synthesis by kynurenines in human lens proteins. Biochim Biophys Acta. 2010 Apr; 1804(4):829-38.
    View in: PubMed
    Score: 0.316
  13. Biswas A, Lewis S, Wang B, Miyagi M, Santoshkumar P, Gangadhariah MH, Nagaraj RH. Chemical modulation of the chaperone function of human alphaA-crystallin. J Biochem. 2008 Jul; 144(1):21-32.
    View in: PubMed
    Score: 0.279
  14. Panja S, Nahomi RB, Rankenberg J, Michel CR, Nagaraj RH. Thiol-Mediated Enhancement of Ne-Acetyllysine Formation in Lens Proteins. ACS Chem Biol. 2024 07 19; 19(7):1495-1505.
    View in: PubMed
    Score: 0.216
  15. Padayatti PS, Ng AS, Uchida K, Glomb MA, Nagaraj RH. Argpyrimidine, a blue fluorophore in human lens proteins: high levels in brunescent cataractous lenses. Invest Ophthalmol Vis Sci. 2001 May; 42(6):1299-304.
    View in: PubMed
    Score: 0.173
  16. Shamsi FA, Sharkey E, Creighton D, Nagaraj RH. Maillard reactions in lens proteins: methylglyoxal-mediated modifications in the rat lens. Exp Eye Res. 2000 Mar; 70(3):369-80.
    View in: PubMed
    Score: 0.160
  17. Nandi SK, Rakete S, Nahomi RB, Michel C, Dunbar A, Fritz KS, Nagaraj RH. Succinylation Is a Gain-of-Function Modification in Human Lens aB-Crystallin. Biochemistry. 2019 03 05; 58(9):1260-1274.
    View in: PubMed
    Score: 0.149
  18. Shamsi FA, Lin K, Sady C, Nagaraj RH. Methylglyoxal-derived modifications in lens aging and cataract formation. Invest Ophthalmol Vis Sci. 1998 Nov; 39(12):2355-64.
    View in: PubMed
    Score: 0.146
  19. Panda AK, Nandi SK, Chakraborty A, Nagaraj RH, Biswas A. Differential role of arginine mutations on the structure and functions of a-crystallin. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):199-210.
    View in: PubMed
    Score: 0.115
  20. Nagaraj RH, Monnier VM. Isolation and characterization of a blue fluorophore from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose. Biochim Biophys Acta. 1992 Mar 05; 1116(1):34-42.
    View in: PubMed
    Score: 0.092
  21. Nagaraj RH, Nahomi RB, Shanthakumar S, Linetsky M, Padmanabha S, Pasupuleti N, Wang B, Santhoshkumar P, Panda AK, Biswas A. Acetylation of aA-crystallin in the human lens: effects on structure and chaperone function. Biochim Biophys Acta. 2012 Feb; 1822(2):120-9.
    View in: PubMed
    Score: 0.090
  22. Nagaraj RH, Sell DR, Prabhakaram M, Ortwerth BJ, Monnier VM. High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):10257-61.
    View in: PubMed
    Score: 0.090
  23. Nagaraj RH, Monnier VM. Non-tryptophan fluorescence and high molecular weight protein formation in lens crystallins of rats with chronic galactosemia: prevention by the aldose reductase inhibitor sorbinil. Exp Eye Res. 1990 Oct; 51(4):411-8.
    View in: PubMed
    Score: 0.083
  24. Nagaraj RH, Sarkar P, Mally A, Biemel KM, Lederer MO, Padayatti PS. Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal. Arch Biochem Biophys. 2002 Jun 01; 402(1):110-9.
    View in: PubMed
    Score: 0.047
  25. Chellan P, Nagaraj RH. Early glycation products produce pentosidine cross-links on native proteins. novel mechanism of pentosidine formation and propagation of glycation. J Biol Chem. 2001 Feb 09; 276(6):3895-903.
    View in: PubMed
    Score: 0.042
  26. Shamsi FA, Nagaraj RH. Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses. Curr Eye Res. 1999 Sep; 19(3):276-84.
    View in: PubMed
    Score: 0.039
  27. Chellan P, Nagaraj RH. Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes. Arch Biochem Biophys. 1999 Aug 01; 368(1):98-104.
    View in: PubMed
    Score: 0.038
  28. Nagaraj RH, Shamsi FA, Huber B, Pischetsrieder M. Immunochemical detection of oxalate monoalkylamide, an ascorbate-derived Maillard reaction product in the human lens. FEBS Lett. 1999 Jun 25; 453(3):327-30.
    View in: PubMed
    Score: 0.038
  29. Shipanova IN, Glomb MA, Nagaraj RH. Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct. Arch Biochem Biophys. 1997 Aug 01; 344(1):29-36.
    View in: PubMed
    Score: 0.033
  30. Zhao HR, Nagaraj RH, Abraham EC. The role of alpha- and epsilon-amino groups in the glycation-mediated cross-linking of gammaB-crystallin. Study of three site-directed mutants. J Biol Chem. 1997 May 30; 272(22):14465-9.
    View in: PubMed
    Score: 0.033
  31. Nagaraj RH, Sady C. The presence of a glucose-derived Maillard reaction product in the human lens. FEBS Lett. 1996 Mar 18; 382(3):234-8.
    View in: PubMed
    Score: 0.030
  32. Nagaraj RH, Monnier VM. Protein modification by the degradation products of ascorbate: formation of a novel pyrrole from the Maillard reaction of L-threose with proteins. Biochim Biophys Acta. 1995 Nov 15; 1253(1):75-84.
    View in: PubMed
    Score: 0.030
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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