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Connection

Ram Nagaraj to Pyruvaldehyde

This is a "connection" page, showing publications Ram Nagaraj has written about Pyruvaldehyde.

 
Connection Strength
 
 
 
4.999
 
  1. Panja S, Rankenberg J, Michel C, Cooksley G, Glomb MA, Nagaraj RH. Proximal cysteine residues in proteins promote Ne-carboxyalkylation of lysine residues by a-dicarbonyl compounds. J Biol Chem. 2025 04; 301(4):108377.
    View in: PubMed
    Score: 0.855
  2. Kanade SR, Pasupuleti N, Nagaraj RH. Role of cysteine residues in the enhancement of chaperone function in methylglyoxal-modified human alpha A-crystallin. Mol Cell Biochem. 2009 Feb; 322(1-2):185-91.
    View in: PubMed
    Score: 0.276
  3. Biswas A, Wang B, Miyagi M, Nagaraj RH. Effect of methylglyoxal modification on stress-induced aggregation of client proteins and their chaperoning by human alphaA-crystallin. Biochem J. 2008 Feb 01; 409(3):771-7.
    View in: PubMed
    Score: 0.262
  4. Puttaiah S, Biswas A, Staniszewska M, Nagaraj RH. Methylglyoxal inhibits glycation-mediated loss in chaperone function and synthesis of pentosidine in alpha-crystallin. Exp Eye Res. 2007 May; 84(5):914-21.
    View in: PubMed
    Score: 0.244
  5. Oya-Ito T, Liu BF, Nagaraj RH. Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27. J Cell Biochem. 2006 Sep 01; 99(1):279-91.
    View in: PubMed
    Score: 0.237
  6. Staniszewska MM, Nagaraj RH. Upregulation of glyoxalase I fails to normalize methylglyoxal levels: a possible mechanism for biochemical changes in diabetic mouse lenses. Mol Cell Biochem. 2006 Aug; 288(1-2):29-36.
    View in: PubMed
    Score: 0.230
  7. Nandi SK, Nahomi RB, Rathee S, Gupta N, Mittal SK, Nagaraj RH. DJ-1 in human lenses: Potential role in preventing advanced glycation endproduct formation. Protein Sci. 2025 Dec; 34(12):e70375.
    View in: PubMed
    Score: 0.225
  8. Nagaraj RH, Oya-Ito T, Bhat M, Liu B. Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin. Ann N Y Acad Sci. 2005 Jun; 1043:158-65.
    View in: PubMed
    Score: 0.217
  9. Liu B, Bhat M, Padival AK, Smith DG, Nagaraj RH. Effect of dicarbonyl modification of fibronectin on retinal capillary pericytes. Invest Ophthalmol Vis Sci. 2004 Jun; 45(6):1983-95.
    View in: PubMed
    Score: 0.203
  10. Nagaraj RH, Oya-Ito T, Padayatti PS, Kumar R, Mehta S, West K, Levison B, Sun J, Crabb JW, Padival AK. Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. Biochemistry. 2003 Sep 16; 42(36):10746-55.
    View in: PubMed
    Score: 0.193
  11. Padival AK, Crabb JW, Nagaraj RH. Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells. FEBS Lett. 2003 Sep 11; 551(1-3):113-8.
    View in: PubMed
    Score: 0.193
  12. Mathys KC, Ponnampalam SN, Padival S, Nagaraj RH. Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Biochem Biophys Res Commun. 2002 Oct 04; 297(4):863-9.
    View in: PubMed
    Score: 0.181
  13. Nagaraj RH, Sarkar P, Mally A, Biemel KM, Lederer MO, Padayatti PS. Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal. Arch Biochem Biophys. 2002 Jun 01; 402(1):110-9.
    View in: PubMed
    Score: 0.177
  14. Wilker SC, Chellan P, Arnold BM, Nagaraj RH. Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine. Anal Biochem. 2001 Mar; 290(2):353-8.
    View in: PubMed
    Score: 0.162
  15. Nandi SK, Rankenberg J, Glomb MA, Nagaraj RH. Transient elevation of temperature promotes cross-linking of a-crystallin-client proteins through formation of advanced glycation endproducts: A potential role in presbyopia and cataracts. Biochem Biophys Res Commun. 2020 12 17; 533(4):1352-1358.
    View in: PubMed
    Score: 0.158
  16. Shamsi FA, Sharkey E, Creighton D, Nagaraj RH. Maillard reactions in lens proteins: methylglyoxal-mediated modifications in the rat lens. Exp Eye Res. 2000 Mar; 70(3):369-80.
    View in: PubMed
    Score: 0.151
  17. Shamsi FA, Lin K, Sady C, Nagaraj RH. Methylglyoxal-derived modifications in lens aging and cataract formation. Invest Ophthalmol Vis Sci. 1998 Nov; 39(12):2355-64.
    View in: PubMed
    Score: 0.138
  18. Shamsi FA, Partal A, Sady C, Glomb MA, Nagaraj RH. Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes. J Biol Chem. 1998 Mar 20; 273(12):6928-36.
    View in: PubMed
    Score: 0.132
  19. Shipanova IN, Glomb MA, Nagaraj RH. Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct. Arch Biochem Biophys. 1997 Aug 01; 344(1):29-36.
    View in: PubMed
    Score: 0.126
  20. Nagaraj RH, Shipanova IN, Faust FM. Protein cross-linking by the Maillard reaction. Isolation, characterization, and in vivo detection of a lysine-lysine cross-link derived from methylglyoxal. J Biol Chem. 1996 Aug 09; 271(32):19338-45.
    View in: PubMed
    Score: 0.118
  21. Nagaraj RH, Panda AK, Shanthakumar S, Santhoshkumar P, Pasupuleti N, Wang B, Biswas A. Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics. PLoS One. 2012; 7(1):e30257.
    View in: PubMed
    Score: 0.086
  22. Nagaraj RH, Biswas A, Miller A, Oya-Ito T, Bhat M. The other side of the Maillard reaction. Ann N Y Acad Sci. 2008 Apr; 1126:107-12.
    View in: PubMed
    Score: 0.066
  23. Biswas A, Lewis S, Wang B, Miyagi M, Santoshkumar P, Gangadhariah MH, Nagaraj RH. Chemical modulation of the chaperone function of human alphaA-crystallin. J Biochem. 2008 Jul; 144(1):21-32.
    View in: PubMed
    Score: 0.066
  24. Padival S, Nagaraj RH. Pyridoxamine inhibits maillard reactions in diabetic rat lenses. Ophthalmic Res. 2006; 38(5):294-302.
    View in: PubMed
    Score: 0.059
  25. Biswas A, Miller A, Oya-Ito T, Santhoshkumar P, Bhat M, Nagaraj RH. Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin. Biochemistry. 2006 Apr 11; 45(14):4569-77.
    View in: PubMed
    Score: 0.058
  26. Miller AG, Smith DG, Bhat M, Nagaraj RH. Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions. J Biol Chem. 2006 Apr 28; 281(17):11864-71.
    View in: PubMed
    Score: 0.057
  27. Padayatti PS, Jiang C, Glomb MA, Uchida K, Nagaraj RH. High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells. Curr Eye Res. 2001 Aug; 23(2):106-15.
    View in: PubMed
    Score: 0.042
  28. Glomb MA, Rösch D, Nagaraj RH. N(delta)-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine, a novel methylglyoxal-arginine modification in beer. J Agric Food Chem. 2001 Jan; 49(1):366-72.
    View in: PubMed
    Score: 0.040
  29. Shamsi FA, Nagaraj RH. Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses. Curr Eye Res. 1999 Sep; 19(3):276-84.
    View in: PubMed
    Score: 0.036
  30. Swamy-Mruthinti S, Miriam KC, Kumar SK, Biswas J, Ramakrishnan S, Nagaraj RH, Sulochana KN. Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: a possible role in ocular neovascularization. Curr Eye Res. 2002 Sep; 25(3):139-45.
    View in: PubMed
    Score: 0.011
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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