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Connection

Ram Nagaraj to Aged

This is a "connection" page, showing publications Ram Nagaraj has written about Aged.

 
Connection Strength
  
 
 
0.514
  
  1. Cooksley G, Nam MH, Nahomi RB, Rankenberg J, Smith AJO, Wormstone YM, Wormstone IM, Nagaraj RH. Lens capsule advanced glycation end products induce senescence in epithelial cells: Implications for secondary cataracts. Aging Cell. 2024 10; 23(10):e14249.
    View in: PubMed
    Score: 0.051
  2. Panja S, Nahomi RB, Rankenberg J, Michel CR, Gaikwad H, Nam MH, Nagaraj RH. Aggrelyte-2 promotes protein solubility and decreases lens stiffness through lysine acetylation and disulfide reduction: Implications for treating presbyopia. Aging Cell. 2023 04; 22(4):e13797.
    View in: PubMed
    Score: 0.047
  3. Panja S, Gaikwad H, Rankenberg J, Nam MH, Nagaraj RH. Promotion of Protein Solubility and Reduction in Stiffness in Human Lenses by Aggrelyte-1: Implications for Reversing Presbyopia. Int J Mol Sci. 2023 Jan 22; 24(3).
    View in: PubMed
    Score: 0.046
  4. Rankenberg J, Rakete S, Wagner BD, Patnaik JL, Henning C, Lynch A, Glomb MA, Nagaraj RH. Advanced glycation end products in human diabetic lens capsules. Exp Eye Res. 2021 09; 210:108704.
    View in: PubMed
    Score: 0.042
  5. Nandi SK, Nahomi RB, Rankenberg J, Glomb MA, Nagaraj RH. Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of a-crystallin: Implications for lens aging and presbyopia. J Biol Chem. 2020 04 24; 295(17):5701-5716.
    View in: PubMed
    Score: 0.038
  6. Nandi SK, Rakete S, Nahomi RB, Michel C, Dunbar A, Fritz KS, Nagaraj RH. Succinylation Is a Gain-of-Function Modification in Human Lens aB-Crystallin. Biochemistry. 2019 03 05; 58(9):1260-1274.
    View in: PubMed
    Score: 0.035
  7. Rakete S, Nagaraj RH. UVA Light-mediated Ascorbate Oxidation in Human Lenses. Photochem Photobiol. 2017 07; 93(4):1091-1095.
    View in: PubMed
    Score: 0.031
  8. Raghavan CT, Smuda M, Smith AJ, Howell S, Smith DG, Singh A, Gupta P, Glomb MA, Wormstone IM, Nagaraj RH. AGEs in human lens capsule promote the TGFß2-mediated EMT of lens epithelial cells: implications for age-associated fibrosis. Aging Cell. 2016 06; 15(3):465-76.
    View in: PubMed
    Score: 0.029
  9. Mailankot M, Padmanabha S, Pasupuleti N, Major D, Howell S, Nagaraj RH. Glyoxalase I activity and immunoreactivity in the aging human lens. Biogerontology. 2009 Dec; 10(6):711-20.
    View in: PubMed
    Score: 0.019
  10. Staniszewska M, Nagaraj RH. Detection of kynurenine modifications in proteins using a monoclonal antibody. J Immunol Methods. 2007 Jul 31; 324(1-2):63-73.
    View in: PubMed
    Score: 0.016
  11. Oya-Ito T, Liu BF, Nagaraj RH. Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27. J Cell Biochem. 2006 Sep 01; 99(1):279-91.
    View in: PubMed
    Score: 0.015
  12. Miller AG, Smith DG, Bhat M, Nagaraj RH. Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions. J Biol Chem. 2006 Apr 28; 281(17):11864-71.
    View in: PubMed
    Score: 0.014
  13. Padayatti PS, Ng AS, Uchida K, Glomb MA, Nagaraj RH. Argpyrimidine, a blue fluorophore in human lens proteins: high levels in brunescent cataractous lenses. Invest Ophthalmol Vis Sci. 2001 May; 42(6):1299-304.
    View in: PubMed
    Score: 0.010
  14. Wilker SC, Chellan P, Arnold BM, Nagaraj RH. Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine. Anal Biochem. 2001 Mar; 290(2):353-8.
    View in: PubMed
    Score: 0.010
  15. Sady C, Jiang CL, Chellan P, Madhun Z, Duve Y, Glomb MA, Nagaraj RH. Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins. Biochim Biophys Acta. 2000 Sep 29; 1481(2):255-64.
    View in: PubMed
    Score: 0.010
  16. Shamsi FA, Nagaraj RH. Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses. Curr Eye Res. 1999 Sep; 19(3):276-84.
    View in: PubMed
    Score: 0.009
  17. Chellan P, Nagaraj RH. Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes. Arch Biochem Biophys. 1999 Aug 01; 368(1):98-104.
    View in: PubMed
    Score: 0.009
  18. Nagaraj RH, Shamsi FA, Huber B, Pischetsrieder M. Immunochemical detection of oxalate monoalkylamide, an ascorbate-derived Maillard reaction product in the human lens. FEBS Lett. 1999 Jun 25; 453(3):327-30.
    View in: PubMed
    Score: 0.009
  19. Shamsi FA, Lin K, Sady C, Nagaraj RH. Methylglyoxal-derived modifications in lens aging and cataract formation. Invest Ophthalmol Vis Sci. 1998 Nov; 39(12):2355-64.
    View in: PubMed
    Score: 0.009
  20. Nahomi RB, Sampathkumar S, Myers AM, Elghazi L, Smith DG, Tang J, Lee CA, Kern TS, Nagaraj RH, Fort PE. The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice. Invest Ophthalmol Vis Sci. 2018 04 01; 59(5):2042-2053.
    View in: PubMed
    Score: 0.008
  21. Shamsi FA, Partal A, Sady C, Glomb MA, Nagaraj RH. Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes. J Biol Chem. 1998 Mar 20; 273(12):6928-36.
    View in: PubMed
    Score: 0.008
  22. Smuda M, Henning C, Raghavan CT, Johar K, Vasavada AR, Nagaraj RH, Glomb MA. Comprehensive analysis of maillard protein modifications in human lenses: effect of age and cataract. Biochemistry. 2015 Apr 21; 54(15):2500-7.
    View in: PubMed
    Score: 0.007
  23. Holm T, Raghavan CT, Nahomi R, Nagaraj RH, Kessel L. Effects of photobleaching on selected advanced glycation end products in the human lens. BMC Res Notes. 2015 Jan 16; 8:5.
    View in: PubMed
    Score: 0.007
  24. DiMauro MA, Nandi SK, Raghavan CT, Kar RK, Wang B, Bhunia A, Nagaraj RH, Biswas A. Acetylation of Gly1 and Lys2 promotes aggregation of human ?D-crystallin. Biochemistry. 2014 Nov 25; 53(46):7269-82.
    View in: PubMed
    Score: 0.007
  25. Li Y, Smith D, Li Q, Sheibani N, Huang S, Kern T, Nagaraj RH, Lin F. Antibody-mediated retinal pericyte injury: implications for diabetic retinopathy. Invest Ophthalmol Vis Sci. 2012 Aug 13; 53(9):5520-6.
    View in: PubMed
    Score: 0.006
  26. Nagaraj RH, Monnier VM. Isolation and characterization of a blue fluorophore from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose. Biochim Biophys Acta. 1992 Mar 05; 1116(1):34-42.
    View in: PubMed
    Score: 0.005
  27. Nagaraj RH, Sell DR, Prabhakaram M, Ortwerth BJ, Monnier VM. High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):10257-61.
    View in: PubMed
    Score: 0.005
  28. Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep. 2010; 15(4):161-8.
    View in: PubMed
    Score: 0.005
  29. Ni J, Yuan X, Gu J, Yue X, Gu X, Nagaraj RH, Crabb JW. Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration. Mol Cell Proteomics. 2009 Aug; 8(8):1921-33.
    View in: PubMed
    Score: 0.004
  30. Kessel L, Kalinin S, Nagaraj RH, Larsen M, Johansson LB. Time-resolved and steady-state fluorescence spectroscopic studies of the human lens with comparison to argpyrimidine, pentosidine and 3-OH-kynurenine. Photochem Photobiol. 2002 Nov; 76(5):549-54.
    View in: PubMed
    Score: 0.003
  31. Smith MA, Siedlak SL, Richey PL, Nagaraj RH, Elhammer A, Perry G. Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease. Brain Res. 1996 Apr 22; 717(1-2):99-108.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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