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Connection

Ram Nagaraj to Animals

This is a "connection" page, showing publications Ram Nagaraj has written about Animals.

 
Connection Strength
  
 
 
1.034
  
  1. Panja S, Rankenberg J, Michel C, Cooksley G, Glomb MA, Nagaraj RH. Proximal cysteine residues in proteins promote Ne-carboxyalkylation of lysine residues by a-dicarbonyl compounds. J Biol Chem. 2025 Apr; 301(4):108377.
    View in: PubMed
    Score: 0.051
  2. Panja S, Nahomi RB, Rankenberg J, Michel CR, Gaikwad H, Nam MH, Nagaraj RH. Aggrelyte-2 promotes protein solubility and decreases lens stiffness through lysine acetylation and disulfide reduction: Implications for treating presbyopia. Aging Cell. 2023 04; 22(4):e13797.
    View in: PubMed
    Score: 0.044
  3. Panja S, Gaikwad H, Rankenberg J, Nam MH, Nagaraj RH. Promotion of Protein Solubility and Reduction in Stiffness in Human Lenses by Aggrelyte-1: Implications for Reversing Presbyopia. Int J Mol Sci. 2023 Jan 22; 24(3).
    View in: PubMed
    Score: 0.044
  4. Nam MH, Stankowska DL, Johnson GA, Nahomi RB, Pantcheva MB, Nagaraj RH. Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma. Cell Death Dis. 2022 11 15; 13(11):958.
    View in: PubMed
    Score: 0.043
  5. Nam MH, Nahomi RB, Pantcheva MB, Dhillon A, Chiodo VA, Smith WC, Nagaraj RH. AAV2-Mediated Expression of HspB1 in RGCs Prevents Somal Damage and Axonal Transport Deficits in a Mouse Model of Ocular Hypertension. Transl Vis Sci Technol. 2022 11 01; 11(11):8.
    View in: PubMed
    Score: 0.043
  6. Nam MH, Pantcheva MB, Rankenberg J, Nagaraj RH. Transforming growth factor-?2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE. Biochem J. 2021 06 25; 478(12):2285-2296.
    View in: PubMed
    Score: 0.039
  7. Nandi SK, Rankenberg J, Rakete S, Nahomi RB, Glomb MA, Linetsky MD, Nagaraj RH. Glycation-mediated protein crosslinking and stiffening in mouse lenses are inhibited by carboxitin in vitro. Glycoconj J. 2021 06; 38(3):347-359.
    View in: PubMed
    Score: 0.038
  8. Nahomi RB, Nam MH, Rankenberg J, Rakete S, Houck JA, Johnson GC, Stankowska DL, Pantcheva MB, MacLean PS, Nagaraj RH. Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice. Int J Mol Sci. 2020 Mar 05; 21(5).
    View in: PubMed
    Score: 0.036
  9. Nam MH, Smith AJO, Pantcheva MB, Park KU, Brzezinski JA, Galligan JJ, Fritz K, Wormstone IM, Nagaraj RH. Aspirin inhibits TGF?2-induced epithelial to mesenchymal transition of lens epithelial cells: selective acetylation of K56 and K122 in histone H3. Biochem J. 2020 01 17; 477(1):75-97.
    View in: PubMed
    Score: 0.036
  10. Nahomi RB, Nandi SK, Rakete S, Michel C, Fritz KS, Nagaraj RH. Lysine malonylation and propionylation are prevalent in human lens proteins. Exp Eye Res. 2020 01; 190:107864.
    View in: PubMed
    Score: 0.035
  11. Nandi SK, Nahomi RB, Harris PS, Michel CR, Fritz KS, Nagaraj RH. The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of a-crystallin in mouse lenses. Exp Eye Res. 2019 05; 182:1-9.
    View in: PubMed
    Score: 0.033
  12. Nahomi RB, Nandi SK, Nagaraj RH. A monoclonal antibody targeted to the functional peptide of aB-crystallin inhibits the chaperone and anti-apoptotic activities. J Immunol Methods. 2019 04; 467:37-47.
    View in: PubMed
    Score: 0.033
  13. Nahomi RB, Pantcheva MB, Nagaraj RH. aB-crystallin is essential for the TGF-?2-mediated epithelial to mesenchymal transition of lens epithelial cells. Biochem J. 2016 05 15; 473(10):1455-69.
    View in: PubMed
    Score: 0.027
  14. Nagaraj RH, Nahomi RB, Mueller NH, Raghavan CT, Ammar DA, Petrash JM. Therapeutic potential of a-crystallin. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):252-7.
    View in: PubMed
    Score: 0.025
  15. Nahomi RB, DiMauro MA, Wang B, Nagaraj RH. Identification of peptides in human Hsp20 and Hsp27 that possess molecular chaperone and anti-apoptotic activities. Biochem J. 2015 Jan 01; 465(1):115-25.
    View in: PubMed
    Score: 0.025
  16. Linetsky M, Raghavan CT, Johar K, Fan X, Monnier VM, Vasavada AR, Nagaraj RH. UVA light-excited kynurenines oxidize ascorbate and modify lens proteins through the formation of advanced glycation end products: implications for human lens aging and cataract formation. J Biol Chem. 2014 Jun 13; 289(24):17111-23.
    View in: PubMed
    Score: 0.024
  17. Nahomi RB, Wang B, Raghavan CT, Voss O, Doseff AI, Santhoshkumar P, Nagaraj RH. Chaperone peptides of a-crystallin inhibit epithelial cell apoptosis, protein insolubilization, and opacification in experimental cataracts. J Biol Chem. 2013 May 03; 288(18):13022-35.
    View in: PubMed
    Score: 0.022
  18. Linetsky M, Kaid Johar SR, Meltretter J, Padmanabha S, Parmar T, Vasavada AR, Pischetsrieder M, Nagaraj RH. Determination of dideoxyosone precursors of AGEs in human lens proteins. Arch Biochem Biophys. 2011 Oct; 514(1-2):16-26.
    View in: PubMed
    Score: 0.020
  19. Nagaraj RH, Linetsky M, Stitt AW. The pathogenic role of Maillard reaction in the aging eye. Amino Acids. 2012 Apr; 42(4):1205-20.
    View in: PubMed
    Score: 0.019
  20. Pasupuleti N, Gangadhariah M, Padmanabha S, Santhoshkumar P, Nagaraj RH. The role of the cysteine residue in the chaperone and anti-apoptotic functions of human Hsp27. J Cell Biochem. 2010 May 15; 110(2):408-19.
    View in: PubMed
    Score: 0.018
  21. Mailankot M, Howell S, Nagaraj RH. Kynurenine inhibits fibroblast growth factor 2-mediated expression of crystallins and MIP26 in lens epithelial cells. Biochim Biophys Acta. 2010 Jul-Aug; 1802(7-8):609-20.
    View in: PubMed
    Score: 0.018
  22. Pasupuleti N, Matsuyama S, Voss O, Doseff AI, Song K, Danielpour D, Nagaraj RH. The anti-apoptotic function of human aA-crystallin is directly related to its chaperone activity. Cell Death Dis. 2010; 1:e31.
    View in: PubMed
    Score: 0.018
  23. Mailankot M, Staniszewska MM, Butler H, Caprara MH, Howell S, Wang B, Doller C, Reneker LW, Nagaraj RH. Indoleamine 2,3-dioxygenase overexpression causes kynurenine-modification of proteins, fiber cell apoptosis and cataract formation in the mouse lens. Lab Invest. 2009 May; 89(5):498-512.
    View in: PubMed
    Score: 0.017
  24. Mailankot M, Smith D, Howell S, Wang B, Jacobberger JW, Stefan T, Nagaraj RH. Cell cycle arrest by kynurenine in lens epithelial cells. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5466-75.
    View in: PubMed
    Score: 0.016
  25. Biswas A, Wang B, Miyagi M, Nagaraj RH. Effect of methylglyoxal modification on stress-induced aggregation of client proteins and their chaperoning by human alphaA-crystallin. Biochem J. 2008 Feb 01; 409(3):771-7.
    View in: PubMed
    Score: 0.015
  26. Staniszewska M, Nagaraj RH. Detection of kynurenine modifications in proteins using a monoclonal antibody. J Immunol Methods. 2007 Jul 31; 324(1-2):63-73.
    View in: PubMed
    Score: 0.015
  27. Puttaiah S, Biswas A, Staniszewska M, Nagaraj RH. Methylglyoxal inhibits glycation-mediated loss in chaperone function and synthesis of pentosidine in alpha-crystallin. Exp Eye Res. 2007 May; 84(5):914-21.
    View in: PubMed
    Score: 0.014
  28. Padival S, Nagaraj RH. Pyridoxamine inhibits maillard reactions in diabetic rat lenses. Ophthalmic Res. 2006; 38(5):294-302.
    View in: PubMed
    Score: 0.014
  29. Oya-Ito T, Liu BF, Nagaraj RH. Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27. J Cell Biochem. 2006 Sep 01; 99(1):279-91.
    View in: PubMed
    Score: 0.014
  30. Staniszewska MM, Nagaraj RH. Upregulation of glyoxalase I fails to normalize methylglyoxal levels: a possible mechanism for biochemical changes in diabetic mouse lenses. Mol Cell Biochem. 2006 Aug; 288(1-2):29-36.
    View in: PubMed
    Score: 0.014
  31. Puttaiah S, Zhang Y, Pilch HA, Pfahler C, Oya-Ito T, Sayre LM, Nagaraj RH. Detection of dideoxyosone intermediates of glycation using a monoclonal antibody: characterization of major epitope structures. Arch Biochem Biophys. 2006 Feb 15; 446(2):186-96.
    View in: PubMed
    Score: 0.013
  32. Nagaraj RH, Oya-Ito T, Bhat M, Liu B. Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin. Ann N Y Acad Sci. 2005 Jun; 1043:158-65.
    View in: PubMed
    Score: 0.013
  33. Johnson GA, Krishnamoorthy RR, Nagaraj RH, Stankowska DL. A Neuroprotective Peptide Modulates Retinal cAMP Response Element-Binding Protein (CREB), Synapsin I (SYN1), and Growth-Associated Protein 43 (GAP43) in Rats with Silicone Oil-Induced Ocular Hypertension. Biomolecules. 2025 Feb 03; 15(2).
    View in: PubMed
    Score: 0.013
  34. Liu B, Bhat M, Nagaraj RH. AlphaB-crystallin inhibits glucose-induced apoptosis in vascular endothelial cells. Biochem Biophys Res Commun. 2004 Aug 13; 321(1):254-8.
    View in: PubMed
    Score: 0.012
  35. Liu B, Bhat M, Padival AK, Smith DG, Nagaraj RH. Effect of dicarbonyl modification of fibronectin on retinal capillary pericytes. Invest Ophthalmol Vis Sci. 2004 Jun; 45(6):1983-95.
    View in: PubMed
    Score: 0.012
  36. Nagaraj RH, Oya-Ito T, Padayatti PS, Kumar R, Mehta S, West K, Levison B, Sun J, Crabb JW, Padival AK. Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. Biochemistry. 2003 Sep 16; 42(36):10746-55.
    View in: PubMed
    Score: 0.011
  37. Mathys KC, Ponnampalam SN, Padival S, Nagaraj RH. Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Biochem Biophys Res Commun. 2002 Oct 04; 297(4):863-9.
    View in: PubMed
    Score: 0.011
  38. Nagaraj RH, Sarkar P, Mally A, Biemel KM, Lederer MO, Padayatti PS. Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal. Arch Biochem Biophys. 2002 Jun 01; 402(1):110-9.
    View in: PubMed
    Score: 0.010
  39. Padayatti PS, Jiang C, Glomb MA, Uchida K, Nagaraj RH. High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells. Curr Eye Res. 2001 Aug; 23(2):106-15.
    View in: PubMed
    Score: 0.010
  40. Chellan P, Nagaraj RH. Early glycation products produce pentosidine cross-links on native proteins. novel mechanism of pentosidine formation and propagation of glycation. J Biol Chem. 2001 Feb 09; 276(6):3895-903.
    View in: PubMed
    Score: 0.009
  41. Shamsi FA, Sharkey E, Creighton D, Nagaraj RH. Maillard reactions in lens proteins: methylglyoxal-mediated modifications in the rat lens. Exp Eye Res. 2000 Mar; 70(3):369-80.
    View in: PubMed
    Score: 0.009
  42. Shamsi FA, Nagaraj RH. Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses. Curr Eye Res. 1999 Sep; 19(3):276-84.
    View in: PubMed
    Score: 0.009
  43. Nagaraj RH, Shamsi FA, Huber B, Pischetsrieder M. Immunochemical detection of oxalate monoalkylamide, an ascorbate-derived Maillard reaction product in the human lens. FEBS Lett. 1999 Jun 25; 453(3):327-30.
    View in: PubMed
    Score: 0.009
  44. Shamsi FA, Lin K, Sady C, Nagaraj RH. Methylglyoxal-derived modifications in lens aging and cataract formation. Invest Ophthalmol Vis Sci. 1998 Nov; 39(12):2355-64.
    View in: PubMed
    Score: 0.008
  45. Nahomi RB, Sampathkumar S, Myers AM, Elghazi L, Smith DG, Tang J, Lee CA, Kern TS, Nagaraj RH, Fort PE. The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice. Invest Ophthalmol Vis Sci. 2018 04 01; 59(5):2042-2053.
    View in: PubMed
    Score: 0.008
  46. Shamsi FA, Partal A, Sady C, Glomb MA, Nagaraj RH. Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes. J Biol Chem. 1998 Mar 20; 273(12):6928-36.
    View in: PubMed
    Score: 0.008
  47. Shipanova IN, Glomb MA, Nagaraj RH. Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct. Arch Biochem Biophys. 1997 Aug 01; 344(1):29-36.
    View in: PubMed
    Score: 0.007
  48. Nagaraj RH, Kern TS, Sell DR, Fogarty J, Engerman RL, Monnier VM. Evidence of a glycemic threshold for the formation of pentosidine in diabetic dog lens but not in collagen. Diabetes. 1996 May; 45(5):587-94.
    View in: PubMed
    Score: 0.007
  49. Nagaraj RH, Sady C. The presence of a glucose-derived Maillard reaction product in the human lens. FEBS Lett. 1996 Mar 18; 382(3):234-8.
    View in: PubMed
    Score: 0.007
  50. Panda AK, Nandi SK, Chakraborty A, Nagaraj RH, Biswas A. Differential role of arginine mutations on the structure and functions of a-crystallin. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):199-210.
    View in: PubMed
    Score: 0.006
  51. Nagaraj RH, Prabhakaram M, Ortwerth BJ, Monnier VM. Suppression of pentosidine formation in galactosemic rat lens by an inhibitor of aldose reductase. Diabetes. 1994 Apr; 43(4):580-6.
    View in: PubMed
    Score: 0.006
  52. Nagaraj RH, Monnier VM. Isolation and characterization of a blue fluorophore from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose. Biochim Biophys Acta. 1992 Mar 05; 1116(1):34-42.
    View in: PubMed
    Score: 0.005
  53. Nagaraj RH, Sell DR, Prabhakaram M, Ortwerth BJ, Monnier VM. High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):10257-61.
    View in: PubMed
    Score: 0.005
  54. Nagaraj RH, Monnier VM. Non-tryptophan fluorescence and high molecular weight protein formation in lens crystallins of rats with chronic galactosemia: prevention by the aldose reductase inhibitor sorbinil. Exp Eye Res. 1990 Oct; 51(4):411-8.
    View in: PubMed
    Score: 0.005
  55. Dahm R, Bramke S, Dawczynski J, Nagaraj RH, Kasper M. Developmental aspects of galectin-3 expression in the lens. Histochem Cell Biol. 2003 Mar; 119(3):219-26.
    View in: PubMed
    Score: 0.003
  56. Zhao HR, Nagaraj RH, Abraham EC. The role of alpha- and epsilon-amino groups in the glycation-mediated cross-linking of gammaB-crystallin. Study of three site-directed mutants. J Biol Chem. 1997 May 30; 272(22):14465-9.
    View in: PubMed
    Score: 0.002
  57. Monnier VM, Nagaraj RH, Portero-Otin M, Glomb M, Elgawish AH, Sell DR, Friedlander MA. Structure of advanced Maillard reaction products and their pathological role. Nephrol Dial Transplant. 1996; 11 Suppl 5:20-6.
    View in: PubMed
    Score: 0.002
  58. Portero-Otin M, Nagaraj RH, Monnier VM. Chromatographic evidence for pyrraline formation during protein glycation in vitro and in vivo. Biochim Biophys Acta. 1995 Feb 22; 1247(1):74-80.
    View in: PubMed
    Score: 0.002
  59. Monnier VM, Miyata S, Nagaraj RH, Sell DR. Relevance of the early and advanced Maillard reaction in diabetic neuropathy. Diabet Med. 1993; 10 Suppl 2:103S-106S.
    View in: PubMed
    Score: 0.001
  60. Sell DR, Nagaraj RH, Grandhee SK, Odetti P, Lapolla A, Fogarty J, Monnier VM. Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia. Diabetes Metab Rev. 1991 Dec; 7(4):239-51.
    View in: PubMed
    Score: 0.001
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