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Connection

Gregory Downey to Phosphorylation

This is a "connection" page, showing publications Gregory Downey has written about Phosphorylation.

 
Connection Strength
 
 
 
0.635
 
  1. Aschner Y, Nelson M, Brenner M, Roybal H, Beke K, Meador C, Foster D, Correll KA, Reynolds PR, Anderson K, Redente EF, Matsuda J, Riches DWH, Groshong SD, Pozzi A, Sap J, Wang Q, Rajshankar D, McCulloch CAG, Zemans RL, Downey GP. Protein tyrosine phosphatase-a amplifies transforming growth factor-?-dependent profibrotic signaling in lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L294-L311.
    View in: PubMed
    Score: 0.135
  2. Aschner Y, Downey GP. The Importance of Tyrosine Phosphorylation Control of Cellular Signaling Pathways in Respiratory Disease: pY and pY Not. Am J Respir Cell Mol Biol. 2018 11; 59(5):535-547.
    View in: PubMed
    Score: 0.121
  3. Downey GP, Aschner Y. Taking It Off: New Insights into the Role of Tyrosine Phosphorylation-dependent Pathways in the Pathogenesis of Pulmonary Fibrosis. Am J Respir Crit Care Med. 2017 02 15; 195(4):418-420.
    View in: PubMed
    Score: 0.107
  4. Suzuki T, Yamashita C, Zemans RL, Briones N, Van Linden A, Downey GP. Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway. Am J Respir Cell Mol Biol. 2009 Dec; 41(6):742-55.
    View in: PubMed
    Score: 0.062
  5. Herrera Abreu MT, Wang Q, Vachon E, Suzuki T, Chow CW, Wang Y, Hong O, Villar J, McCulloch CA, Downey GP. Tyrosine phosphatase SHP-2 regulates IL-1 signaling in fibroblasts through focal adhesions. J Cell Physiol. 2006 Apr; 207(1):132-43.
    View in: PubMed
    Score: 0.051
  6. Ginzberg HH, Shannon PT, Suzuki T, Hong O, Vachon E, Moraes T, Abreu MT, Cherepanov V, Wang X, Chow CW, Downey GP. Leukocyte elastase induces epithelial apoptosis: role of mitochondial permeability changes and Akt. Am J Physiol Gastrointest Liver Physiol. 2004 Jul; 287(1):G286-98.
    View in: PubMed
    Score: 0.045
  7. Wang Q, Notay K, Downey GP, McCulloch CA. The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation. Cell Rep. 2020 06 30; 31(13):107781.
    View in: PubMed
    Score: 0.034
  8. Wang Q, Siminovitch KA, Downey GP, McCulloch CA. Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLC? at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression. Biochem J. 2013 Feb 01; 449(3):771-82.
    View in: PubMed
    Score: 0.020
  9. McCulloch CA, Downey GP, El-Gabalawy H. Signalling platforms that modulate the inflammatory response: new targets for drug development. Nat Rev Drug Discov. 2006 Oct; 5(10):864-76.
    View in: PubMed
    Score: 0.013
  10. Wang Q, Herrera Abreu MT, Siminovitch K, Downey GP, McCulloch CA. Phosphorylation of SHP-2 regulates interactions between the endoplasmic reticulum and focal adhesions to restrict interleukin-1-induced Ca2+ signaling. J Biol Chem. 2006 Oct 13; 281(41):31093-105.
    View in: PubMed
    Score: 0.013
  11. Wang Q, Downey GP, Herrera-Abreu MT, Kapus A, McCulloch CA. SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1. J Biol Chem. 2005 Mar 04; 280(9):8397-406.
    View in: PubMed
    Score: 0.012
  12. Huynh H, Bottini N, Williams S, Cherepanov V, Musumeci L, Saito K, Bruckner S, Vachon E, Wang X, Kruger J, Chow CW, Pellecchia M, Monosov E, Greer PA, Trimble W, Downey GP, Mustelin T. Control of vesicle fusion by a tyrosine phosphatase. Nat Cell Biol. 2004 Sep; 6(9):831-9.
    View in: PubMed
    Score: 0.011
  13. Wang Q, Downey GP, Choi C, Kapus A, McCulloch CA. IL-1 induced release of Ca2+ from internal stores is dependent on cell-matrix interactions and regulates ERK activation. FASEB J. 2003 Oct; 17(13):1898-900.
    View in: PubMed
    Score: 0.011
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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