Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.
 Back to Details

Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Angelo D'Alessandro and Travis Nemkov.

 
Connection Strength
  
 
 
29.941
  
  1. Nemkov T, Stauffer E, Cendali F, Stephenson D, Nader E, Robert M, Skinner S, Dzieciatkowska M, Hansen KC, Robach P, Millet GY, Connes P, D'Alessandro A. Long-Distance Trail Running Induces Inflammatory-Associated Protein, Lipid, and Purine Oxidation in Red Blood Cells. Blood Red Cells Iron. 2026 Mar; 2(1).
    View in: PubMed
    Score: 0.970
  2. Nemkov T, Stauffer E, Cendali F, Stephenson D, Nader E, Robert M, Skinner S, Dzieciatkowska M, Hansen KC, Robach P, Millet GY, Connes P, D'Alessandro A. Long-Distance Trail Running Induces Inflammatory-Associated Protein, Lipid, and Purine Oxidation in Red Blood Cells. bioRxiv. 2025 May 19.
    View in: PubMed
    Score: 0.918
  3. Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman ZB, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A. Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes. Cell Metab. 2024 Sep 03; 36(9):1979-1997.e13.
    View in: PubMed
    Score: 0.864
  4. Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro. Blood. 2024 06 13; 143(24):2517-2533.
    View in: PubMed
    Score: 0.861
  5. Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman Z, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A. Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes. bioRxiv. 2024 Jun 11.
    View in: PubMed
    Score: 0.860
  6. Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife T, Kleinman S, Zimring JC, Roubinian N, Hansen KC, Busch MP, Norris PJ, D'Alessandro A. Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo. Blood. 2024 02 01; 143(5):456-472.
    View in: PubMed
    Score: 0.839
  7. Nemkov T, Cendali F, Stefanoni D, Martinez JL, Hansen KC, San-Millán I, D'Alessandro A. Metabolic Signatures of Performance in Elite World Tour Professional Male Cyclists. Sports Med. 2023 08; 53(8):1651-1665.
    View in: PubMed
    Score: 0.797
  8. Nemkov T, Skinner S, Diaw M, Diop S, Samb A, Connes P, D'Alessandro A. Plasma Levels of Acyl-Carnitines and Carboxylic Acids Correlate With Cardiovascular and Kidney Function in Subjects With Sickle Cell Trait. Front Physiol. 2022; 13:916197.
    View in: PubMed
    Score: 0.753
  9. Nemkov T, Yoshida T, Nikulina M, D'Alessandro A. High-Throughput Metabolomics Platform for the Rapid Data-Driven Development of Novel Additive Solutions for Blood Storage. Front Physiol. 2022; 13:833242.
    View in: PubMed
    Score: 0.736
  10. Nemkov T, Skinner SC, Nader E, Stefanoni D, Robert M, Cendali F, Stauffer E, Cibiel A, Boisson C, Connes P, D'Alessandro A. Acute Cycling Exercise Induces Changes in Red Blood Cell Deformability and Membrane Lipid Remodeling. Int J Mol Sci. 2021 Jan 18; 22(2).
    View in: PubMed
    Score: 0.680
  11. Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A. Decoding the metabolic landscape of pathophysiological stress-induced cell death in anucleate red blood cells. Blood Transfus. 2020 03; 18(2):130-142.
    View in: PubMed
    Score: 0.639
  12. Nemkov T, Reisz JA, Gehrke S, Hansen KC, D'Alessandro A. High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods. Methods Mol Biol. 2019; 1978:13-26.
    View in: PubMed
    Score: 0.590
  13. Nemkov T, Reisz JA, Xia Y, Zimring JC, D'Alessandro A. Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport. Expert Rev Proteomics. 2018 11; 15(11):855-864.
    View in: PubMed
    Score: 0.581
  14. Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A. Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage. Haematologica. 2018 02; 103(2):361-372.
    View in: PubMed
    Score: 0.544
  15. Nemkov T, Sun K, Reisz JA, Yoshida T, Dunham A, Wen EY, Wen AQ, Roach RC, Hansen KC, Xia Y, D'Alessandro A. Metabolism of Citrate and Other Carboxylic Acids in Erythrocytes As a Function of Oxygen Saturation and Refrigerated Storage. Front Med (Lausanne). 2017; 4:175.
    View in: PubMed
    Score: 0.543
  16. Nemkov T, Hansen KC, D'Alessandro A. A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways. Rapid Commun Mass Spectrom. 2017 Apr 30; 31(8):663-673.
    View in: PubMed
    Score: 0.525
  17. Nemkov T, Hansen KC, Dumont LJ, D'Alessandro A. Metabolomics in transfusion medicine. Transfusion. 2016 Apr; 56(4):980-93.
    View in: PubMed
    Score: 0.477
  18. Keele GR, Nemkov T, Hay AM, Vincent M, O'Connor C, Stephenson D, Page GP, Zimring JC, Churchill GA, D'Alessandro A. Genetic architecture of the murine serum metabolome reveals carboxyl esterases as master regulators of circulating fatty acid metabolism. bioRxiv. 2026 Jun 28.
    View in: PubMed
    Score: 0.248
  19. Issaian AV, Dzieciatkowska M, Bevers S, Safari Z, Hay AM, Cendali FI, Argabright A, Rogers SC, Saviola AJ, Redzic JS, Wartchow E, Reisz Haines J, Keele GR, Haiman ZB, Nemkov T, Stephenson D, Lisk C, Vallese F, Palsson BO, King SB, Page GP, Doctor A, Hudson KE, Hansen KC, Irwin DC, Mohandas N, Zimring JC, Eisenmesser EZ, D'Alessandro A. The red blood cell proteome and interactome identify a Band 3-BLVRB axis regulating hypoxic metabolic adaptation. Blood. 2026 Jun 01.
    View in: PubMed
    Score: 0.247
  20. Bevers S, Issaian AV, Hay A, Keele GR, Dzieciatkowska M, Reisz JA, Haiman ZB, Nemkov T, Stephenson D, Moore AL, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Palsson BO, Roubinian NH, Janetzko J, V?geli B, Page GP, Jones DN, Henen MA, Eisenmesser EZ, Zimring JC, D'Alessandro A. Improved red blood cell storage quality of blood from donors carrying the hypermorphic PIMT I120 variant. Hemasphere. 2026 Apr; 10(4):e70361.
    View in: PubMed
    Score: 0.244
  21. Dzieciatkowska M, Stephenson D, Hay A, Wang X, Keele GR, Nemkov T, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Page GP, Spitalnik SL, Roubinian N, Zimring JC, Thein SL, D'Alessandro A. Lower efficacy of transfusion of red blood cells from donors with sickle cell trait. Hemasphere. 2026 Apr; 10(4):e70360.
    View in: PubMed
    Score: 0.244
  22. Dzieciatkowska M, Issaian AV, Keele GR, Saviola A, Stephenson D, Bevers S, Reisz JA, Haiman ZB, Nemkov T, Fang F, Moore AL, Deng X, Stone M, Kleinman S, Norris PJ, Wang X, Thein SL, Hod EA, Busch MP, Roubinian NH, Page GP, Hansen KC, D'Alessandro A. A population-scale Red Blood Cell proteome atlas of 13,000 donors uncovers genetically encoded aging clocks predicting hemolysis, transfusion efficacy, and donor activity a decade later. bioRxiv. 2026 Mar 08.
    View in: PubMed
    Score: 0.243
  23. D'Alessandro A, Nemkov T, L'Acqua C, Spitalnik SL, Hod EA. Reproducibility of metabolic signatures in blood unit segments versus transfusates. Transfusion. 2026 Mar; 66(3):439-443.
    View in: PubMed
    Score: 0.240
  24. Issaian AV, Dzieciatkowska M, Bevers S, Zohreh S, Hay A, Saviola A, Redzic JS, Reisz JA, Keele GR, Cendali FI, Haiman ZB, Nemkov T, Stephenson D, Lisk C, Vallese F, Palsson BO, King SB, Page GP, Doctor A, Hudson K, Hansen KC, Irwin DC, Mohandas N, Zimring JC, Eisenmesser EZ, D'Alessandro A. Deep Red Blood Cell Proteome Defines the Band 3 N-Terminus Interactome as a Regulator of Hypoxic Adaptation via BLVRB-Dependent S -Nitroso Transfer. bioRxiv. 2025 Nov 30.
    View in: PubMed
    Score: 0.238
  25. Roubinian NH, Plimier C, Fang F, Page GP, Nemkov T, Kanias T, Custer B, Kleinman S, Norris PJ, Busch MP, D'Alessandro A. Integrated analysis of blood donor metabolic phenotypes and genetic traits on red blood cell transfusion effectiveness. Blood Red Cells Iron. 2025 Dec; 1(3).
    View in: PubMed
    Score: 0.238
  26. Karafin MS, Issaian AV, Bevers S, Reisz JA, Hay A, Keele GR, Dzieciatkowska M, Cendali FI, Haiman ZB, Key AM, Nemkov T, Stephenson D, Marsh E, Moore AL, Palha MS, Legenzov EA, Lamb DR, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Vallese F, Palsson BO, Spitalnik SL, Kao JPY, Roubinian NH, Janetzko J, Page GP, Eisenmesser EZ, Zimring JC, Buehler PW, D'Alessandro A. Genetic variation of human G6PD impacts Red Blood Cell transfusion efficacy. bioRxiv. 2025 Nov 22.
    View in: PubMed
    Score: 0.238
  27. Keele GR, Dzieciatkowska M, Hay AM, Vincent M, O'Connor C, Stephenson D, Reisz JA, Nemkov T, Hansen KC, Page GP, Zimring JC, Churchill GA, D'Alessandro A. Genetic architecture of the murine red blood cell proteome reveals central role of hemoglobin beta cysteine 93 in maintaining redox balance. Cell Genom. 2026 Mar 11; 6(3):101069.
    View in: PubMed
    Score: 0.238
  28. Nemkov T, Isiksacan Z, William N, Senturk R, Boudreau LE, Yarmush ML, Acker JP, D'Alessandro A, Usta OB. Supercooled storage of red blood cells slows down the metabolic storage lesion. Sci Rep. 2025 Oct 03; 15(1):34574.
    View in: PubMed
    Score: 0.236
  29. Stephenson D, Keele GR, Hay A, Dzieciatkowska M, Reisz JA, Haiman ZB, Moore AL, Nemkov T, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Churchill GA, Stockwell BR, Roubinian N, Zimring JC, Page GP, D'Alessandro A. GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells. Blood Red Cells Iron. 2025 Dec; 1(3).
    View in: PubMed
    Score: 0.235
  30. Dzieciatkowska M, Hay A, Issaian A, Keele GR, Bevers S, Nemkov T, Reisz JA, Maslanka M, Stephenson D, Moore AL, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Page GP, Roubinian N, Xia Y, Zimring JC, D'Alessandro A. Caffeine impairs red blood cell storage quality by dual inhibition of ADORA2b signaling and G6PD activity. Haematologica. 2026 Mar 01; 111(3):861-875.
    View in: PubMed
    Score: 0.234
  31. Cendali FI, Grier AL, Lisk C, Dzieciatkowska M, Haiman Z, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow EP, Buehler PW, Hansen KC, Nemkov T, Zimring JC, Irwin DC, D'Alessandro A. Increased Exercise Tolerance in G6PD African Variant Mice Driven by Metabolic Adaptations and Erythrophagocytosis. Antioxidants (Basel). 2025 Jul 29; 14(8).
    View in: PubMed
    Score: 0.233
  32. Roberti D, Grier AL, Reisz JA, Vallefuoco F, Key A, Bevers S, Dzieciatkowska M, Nemkov T, Contieri M, Zanfardino A, Norris PJ, Busch MP, Kauffman V, Morton HD, Earley EJ, Page GP, Marzuillo P, D'Alessandro A. Altered branched chain ketoacids underlie shared metabolic phenotypes in type 1 diabetes and maple syrup urine disease. Commun Med (Lond). 2025 Jul 26; 5(1):311.
    View in: PubMed
    Score: 0.232
  33. Dzieciatkowska M, Hay A, Issaian A, Keele GR, Bevers S, Nemkov T, Reisz JA, Maslanka M, Stephenson D, Moore AL, Deng X, Stone M, Hansen KC, Kleinman S, Norris PJ, Busch MP, Page GP, Roubinian N, Xia Y, Zimring JC, D'Alessandro A. Caffeine Impairs Red Blood Cell Storage Quality by Dual Inhibition of ADORA2b Signaling and G6PD Activity. bioRxiv. 2025 May 30.
    View in: PubMed
    Score: 0.230
  34. Keele GR, Dzieciatkowska M, Hay AM, Vincent M, O'Connor C, Stephenson D, Reisz JA, Nemkov T, Hansen KC, Page GP, Zimring JC, Churchill GA, D'Alessandro A. Genetic architecture of the red blood cell proteome in genetically diverse mice reveals central role of hemoglobin beta cysteine redox status in maintaining circulating glutathione pools. bioRxiv. 2025 Mar 04.
    View in: PubMed
    Score: 0.226
  35. Nemkov T, Isiksacan Z, William N, Senturk R, Boudreau LE, Yarmush ML, Acker JP, D'Alessandro A, Usta OB. Supercooled storage of red blood cells slows down the metabolic storage lesion. Res Sq. 2025 Feb 27.
    View in: PubMed
    Score: 0.226
  36. D'Alessandro A, Keele GR, Hay A, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman S, Spitalnik SL, Roubinian N, Norris PJ, Busch MP, Page GP, Stockwell BR, Churchill GA, Zimring JC. Ferroptosis regulates hemolysis in stored murine and human red blood cells. Blood. 2025 Feb 13; 145(7):765-783.
    View in: PubMed
    Score: 0.225
  37. Cendali FI, Lisk C, Dzieciatkowska M, LaCroix IS, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow EP, Darehshouri A, Dziewulska-Cronk KH, Buehler PW, Norris PJ, Deng X, Busch MP, Earley EJ, Page GP, Hansen KC, Zimring JC, Irwin DC, Nemkov T, D'Alessandro A. Increased exercise tolerance in humanized G6PD-deficient mice. Blood Adv. 2025 Jan 28; 9(2):321-334.
    View in: PubMed
    Score: 0.225
  38. Key AM, Earley EJ, Tzounakas VL, Anastasiadi AT, Nemkov T, Stephenson D, Dzieciatkowska M, Reisz JA, Keele GR, Deng X, Stone M, Kleinman S, Hansen KC, Norris PJ, Busch MP, Roubinian NH, Page GP, D'Alessandro A. Red blood cell urate levels are linked to hemolysis in vitro and post-transfusion as a function of donor sex, population and genetic polymorphisms in SLC2A9 and ABCG2. Transfusion. 2025 Mar; 65(3):560-574.
    View in: PubMed
    Score: 0.224
  39. Reisz JA, Earley EJ, Nemkov T, Key A, Stephenson D, Keele GR, Dzieciatkowska M, Spitalnik SL, Hod EA, Kleinman S, Roubinian NH, Gladwin MT, Hansen KC, Norris PJ, Busch MP, Zimring JC, Churchill GA, Page GP, D'Alessandro A. Arginine metabolism is a biomarker of red blood cell and human aging. Aging Cell. 2025 02; 24(2):e14388.
    View in: PubMed
    Score: 0.221
  40. D'Alessandro A, Keele GR, Hay A, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman S, Spitalnik SL, Roubinian NH, Norris PJ, Busch MP, Page GP, Stockwell BR, Churchill GA, Zimring JC. Ferroptosis regulates hemolysis in stored murine and human red blood cells. bioRxiv. 2024 Jun 11.
    View in: PubMed
    Score: 0.215
  41. Nemkov T, Cendali F, Dzieciatkowska M, Stephenson D, Hansen KC, Jankowski CM, D'Alessandro A, Marker RJ. A Multiomics Assessment of Preoperative Exercise in Pancreatic Cancer Survivors Receiving Neoadjuvant Therapy: A Case Series. Pathophysiology. 2024 Mar 20; 31(1):166-182.
    View in: PubMed
    Score: 0.212
  42. D'Alessandro A, Earley EJ, Nemkov T, Stephenson D, Dzieciatkowska M, Hansen KC, Minetti G, Champigneulle B, Stauffer E, Pichon A, Furian M, Verges S, Kleinman S, Norris PJ, Busch MP, Page GP, Kaestner L. Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude. Proc Natl Acad Sci U S A. 2024 Jan 02; 121(1):e2315930120.
    View in: PubMed
    Score: 0.208
  43. D'Alessandro A, Anastasiadi AT, Tzounakas VL, Nemkov T, Reisz JA, Kriebardis AG, Zimring JC, Spitalnik SL, Busch MP. Red Blood Cell Metabolism In Vivo and In Vitro. Metabolites. 2023 Jun 27; 13(7).
    View in: PubMed
    Score: 0.201
  44. Skinner SC, Nemkov T, Diaw M, Mbaye MN, Diedhiou D, Sow D, Gueye F, Lopez P, Connes P, D'Alessandro A. Metabolic Profile of Individuals with and without Type 2 Diabetes from Sub-Saharan Africa. J Proteome Res. 2023 07 07; 22(7):2319-2326.
    View in: PubMed
    Score: 0.200
  45. Hay A, Nemkov T, Gamboni F, Dzieciatkowska M, Key A, Galbraith M, Bartsch K, Sun K, Xia Y, Stone M, Busch MP, Norris PJ, Zimring JC, D'Alessandro A. Sphingosine 1-phosphate has a negative effect on RBC storage quality. Blood Adv. 2023 04 25; 7(8):1379-1393.
    View in: PubMed
    Score: 0.199
  46. Cendali FI, Nemkov T, Lisk C, Lacroix IS, Nouraie SM, Zhang Y, Gordeuk VR, Buehler PW, Irwin D, D'Alessandro A. Metabolic correlates to critical speed in murine models of sickle cell disease. Front Physiol. 2023; 14:1151268.
    View in: PubMed
    Score: 0.197
  47. Cendali F, D'Alessandro A, Nemkov T. Dried blood spot characterization of sex-based metabolic responses to acute running exercise. Anal Sci Adv. 2023 Feb; 4(1-2):37-48.
    View in: PubMed
    Score: 0.196
  48. LaCroix IS, Cohen M, Moore EE, Dzieciatkowska M, Nemkov T, Schaid TR, Debot M, Jones K, Silliman CC, Hansen KC, D'Alessandro A. Omics Markers of Red Blood Cell Transfusion in Trauma. Int J Mol Sci. 2022 Nov 10; 23(22).
    View in: PubMed
    Score: 0.193
  49. Guntur VP, Nemkov T, de Boer E, Mohning MP, Baraghoshi D, Cendali FI, San-Millán I, Petrache I, D'Alessandro A. Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC). Metabolites. 2022 Oct 26; 12(11).
    View in: PubMed
    Score: 0.192
  50. Miglio A, Maslanka M, Di Tommaso M, Rocconi F, Nemkov T, Buehler PW, Antognoni MT, Spitalnik SL, D'Alessandro A. ZOOMICS : comparative metabolomics of red blood cells from dogs, cows, horses and donkeys during refrigerated storage for up to 42 days. Blood Transfus. 2023 07; 21(4):314-326.
    View in: PubMed
    Score: 0.189
  51. Nemkov T, Kingsley PD, Dzieciatkowska M, Malik J, McGrath KE, Hansen KC, D'Alessandro A, Palis J. Circulating primitive murine erythroblasts undergo complex proteomic and metabolomic changes during terminal maturation. Blood Adv. 2022 05 24; 6(10):3072-3089.
    View in: PubMed
    Score: 0.187
  52. Stephenson D, Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A. Inductively-Coupled Plasma Mass Spectrometry-Novel Insights From an Old Technology Into Stressed Red Blood Cell Physiology. Front Physiol. 2022; 13:828087.
    View in: PubMed
    Score: 0.183
  53. Kalani Roy M, La Carpia F, Cendali F, Fernando S, Moriconi C, Wojczyk BS, Wang L, Nemkov T, Hod EA, D'Alessandro A. Irradiation Causes Alterations of Polyamine, Purine, and Sulfur Metabolism in Red Blood Cells and Multiple Organs. J Proteome Res. 2022 02 04; 21(2):519-534.
    View in: PubMed
    Score: 0.182
  54. D'Alessandro A, Thomas T, Akpan IJ, Reisz JA, Cendali FI, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh D, Moriconi C, Zimring JC, Hod EA, Spitalnik SL, Buehler PW, Francis RO. Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Cells. 2021 09 02; 10(9).
    View in: PubMed
    Score: 0.177
  55. D'Alessandro A, Akpan I, Thomas T, Reisz J, Cendali F, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei A, Valk J, Hudson K, Roh D, Moriconi C, Zimring J, Hod E, Spitalnik S, Buehler P, Francis R. Biological and Clinical Factors contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Res Sq. 2021 May 10.
    View in: PubMed
    Score: 0.174
  56. Thomas T, Cendali F, Fu X, Gamboni F, Morrison EJ, Beirne J, Nemkov T, Antonelou MH, Kriebardis A, Welsby I, Hay A, Dziewulska KH, Busch MP, Kleinman S, Buehler PW, Spitalnik SL, Zimring JC, D'Alessandro A. Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality. Transfusion. 2021 06; 61(6):1867-1883.
    View in: PubMed
    Score: 0.173
  57. Nemkov T, Stefanoni D, Bordbar A, Issaian A, Palsson BO, Dumont LJ, Hay A, Song A, Xia Y, Redzic JS, Eisenmesser EZ, Zimring JC, Kleinman S, Hansen KC, Busch MP, D'Alessandro A. Blood donor exposome and impact of common drugs on red blood cell metabolism. JCI Insight. 2021 02 08; 6(3).
    View in: PubMed
    Score: 0.171
  58. Thomas T, Stefanoni D, Dzieciatkowska M, Issaian A, Nemkov T, Hill RC, Francis RO, Hudson KE, Buehler PW, Zimring JC, Hod EA, Hansen KC, Spitalnik SL, D'Alessandro A. Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. J Proteome Res. 2020 11 06; 19(11):4455-4469.
    View in: PubMed
    Score: 0.167
  59. Bertolone L, Shin HK, Stefanoni D, Baek JH, Gao Y, Morrison EJ, Nemkov T, Thomas T, Francis RO, Hod EA, Zimring JC, Yoshida T, Karafin M, Schwartz J, Hudson KE, Spitalnik SL, Buehler PW, D'Alessandro A. ZOOMICS: Comparative Metabolomics of Red Blood Cells From Old World Monkeys and Humans. Front Physiol. 2020; 11:593841.
    View in: PubMed
    Score: 0.167
  60. Thomas T, Stefanoni D, Reisz JA, Nemkov T, Bertolone L, Francis RO, Hudson KE, Zimring JC, Hansen KC, Hod EA, Spitalnik SL, D'Alessandro A. COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight. 2020 07 23; 5(14).
    View in: PubMed
    Score: 0.164
  61. Thomas T, Stefanoni D, Dzieciatkowska M, Issaian A, Nemkov T, Hill RC, Francis RO, Hudson KE, Buehler PW, Zimring JC, Hod EA, Hansen KC, Spitalnik SL, D'Alessandro A. Evidence for structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients. medRxiv. 2020 Jun 30.
    View in: PubMed
    Score: 0.164
  62. San-Millán I, Stefanoni D, Martinez JL, Hansen KC, D'Alessandro A, Nemkov T. Metabolomics of Endurance Capacity in World Tour Professional Cyclists. Front Physiol. 2020; 11:578.
    View in: PubMed
    Score: 0.163
  63. Thomas T, Stefanoni D, Reisz JA, Nemkov T, Bertolone L, Francis RO, Hudson KE, Zimring JC, Hansen KC, Hod EA, Spitalnik SL, D'Alessandro A. COVID-19 infection results in alterations of the kynurenine pathway and fatty acid metabolism that correlate with IL-6 levels and renal status. medRxiv. 2020 May 16.
    View in: PubMed
    Score: 0.162
  64. Bertolone L, Roy MK, Hay AM, Morrison EJ, Stefanoni D, Fu X, Kanias T, Kleinman S, Dumont LJ, Stone M, Nemkov T, Busch MP, Zimring JC, D'Alessandro A. Impact of taurine on red blood cell metabolism and implications for blood storage. Transfusion. 2020 06; 60(6):1212-1226.
    View in: PubMed
    Score: 0.162
  65. D'Alessandro A, Yoshida T, Nestheide S, Nemkov T, Stocker S, Stefanoni D, Mohmoud F, Rugg N, Dunham A, Cancelas JA. Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery. Transfusion. 2020 04; 60(4):786-798.
    View in: PubMed
    Score: 0.160
  66. Stefanoni D, Shin HKH, Baek JH, Champagne DP, Nemkov T, Thomas T, Francis RO, Zimring JC, Yoshida T, Reisz JA, Spitalnik SL, Buehler PW, D'Alessandro A. Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage. Haematologica. 2020 08; 105(8):2174-2186.
    View in: PubMed
    Score: 0.156
  67. Morrison EJ, Champagne DP, Dzieciatkowska M, Nemkov T, Zimring JC, Hansen KC, Guan F, Huffman DM, Santambrogio L, D'Alessandro A. Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells. Nutrients. 2019 Jun 14; 11(6).
    View in: PubMed
    Score: 0.152
  68. Gehrke S, Rice S, Stefanoni D, Wilkerson RB, Nemkov T, Reisz JA, Hansen KC, Lucas A, Cabrales P, Drew K, D'Alessandro A. Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel. J Proteome Res. 2019 04 05; 18(4):1827-1841.
    View in: PubMed
    Score: 0.149
  69. Reisz JA, Zheng C, D'Alessandro A, Nemkov T. Untargeted and Semi-targeted Lipid Analysis of Biological Samples Using Mass Spectrometry-Based Metabolomics. Methods Mol Biol. 2019; 1978:121-135.
    View in: PubMed
    Score: 0.147
  70. D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC. Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics. Transfusion. 2019 01; 59(1):89-100.
    View in: PubMed
    Score: 0.146
  71. Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A. Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells. Transfusion. 2018 12; 58(12):2978-2991.
    View in: PubMed
    Score: 0.145
  72. Nemkov T, D'Alessandro A, Reisz JA. Metabolic underpinnings of leukemia pathology and treatment. Cancer Rep (Hoboken). 2019 04; 2(2):e1139.
    View in: PubMed
    Score: 0.145
  73. Catala A, Culp-Hill R, Nemkov T, D'Alessandro A. Quantitative metabolomics comparison of traditional blood draws and TAP capillary blood collection. Metabolomics. 2018 07 12; 14(7):100.
    View in: PubMed
    Score: 0.143
  74. Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A. When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. Expert Rev Proteomics. 2018 04; 15(4):293-309.
    View in: PubMed
    Score: 0.140
  75. Culp-Hill R, Zheng C, Reisz JA, Smith K, Rachubinski A, Nemkov T, Butcher E, Granrath R, Hansen KC, Espinosa JM, D'Alessandro A. Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging. Blood Adv. 2017 Dec 26; 1(27):2776-2780.
    View in: PubMed
    Score: 0.137
  76. Clendenen N, Nunns GR, Moore EE, Reisz JA, Gonzalez E, Peltz E, Silliman CC, Fragoso M, Nemkov T, Wither MJ, Hansen K, Banerjee A, Moore HB, D'Alessandro A. Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine. J Trauma Acute Care Surg. 2017 10; 83(4):635-642.
    View in: PubMed
    Score: 0.135
  77. Gehrke S, Reisz JA, Nemkov T, Hansen KC, D'Alessandro A. Characterization of rapid extraction protocols for high-throughput metabolomics. Rapid Commun Mass Spectrom. 2017 Sep 15; 31(17):1445-1452.
    View in: PubMed
    Score: 0.135
  78. D'alessandro A, Nemkov T, Reisz J, Dzieciatkowska M, Wither MJ, Hansen KC. Omics markers of the red cell storage lesion and metabolic linkage. Blood Transfus. 2017 Mar; 15(2):137-144.
    View in: PubMed
    Score: 0.130
  79. D'Alessandro A, Dzieciatkowska M, Nemkov T, Hansen KC. Red blood cell proteomics update: is there more to discover? Blood Transfus. 2017 03; 15(2):182-187.
    View in: PubMed
    Score: 0.130
  80. D'Alessandro A, Nemkov T, Bogren LK, Martin SL, Hansen KC. Comfortably Numb and Back: Plasma Metabolomics Reveals Biochemical Adaptations in the Hibernating 13-Lined Ground Squirrel. J Proteome Res. 2017 02 03; 16(2):958-969.
    View in: PubMed
    Score: 0.128
  81. D'Alessandro A, Nemkov T, Yoshida T, Bordbar A, Palsson BO, Hansen KC. Citrate metabolism in red blood cells stored in additive solution-3. Transfusion. 2017 02; 57(2):325-336.
    View in: PubMed
    Score: 0.127
  82. D'Alessandro A, Nemkov T, Sun K, Liu H, Song A, Monte AA, Subudhi AW, Lovering AT, Dvorkin D, Julian CG, Kevil CG, Kolluru GK, Shiva S, Gladwin MT, Xia Y, Hansen KC, Roach RC. AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia. J Proteome Res. 2016 10 07; 15(10):3883-3895.
    View in: PubMed
    Score: 0.126
  83. D'Alessandro A, Moore HB, Moore EE, Wither MJ, Nemkov T, Morton AP, Gonzalez E, Chapman MP, Fragoso M, Slaughter A, Sauaia A, Silliman CC, Hansen KC, Banerjee A. Plasma First Resuscitation Reduces Lactate Acidosis, Enhances Redox Homeostasis, Amino Acid and Purine Catabolism in a Rat Model of Profound Hemorrhagic Shock. Shock. 2016 08; 46(2):173-82.
    View in: PubMed
    Score: 0.125
  84. Reisz JA, Wither MJ, Dzieciatkowska M, Nemkov T, Issaian A, Yoshida T, Dunham AJ, Hill RC, Hansen KC, D'Alessandro A. Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. Blood. 2016 09 22; 128(12):e32-42.
    View in: PubMed
    Score: 0.124
  85. D'alessandro A, Nemkov T, Moore HB, Moore EE, Wither M, Nydam T, Slaughter A, Silliman CC, Banerjee A, Hansen KC. Metabolomics of trauma-associated death: shared and fluid-specific features of human plasma vs lymph. Blood Transfus. 2016 05; 14(2):185-94.
    View in: PubMed
    Score: 0.122
  86. D'alessandro A, Nemkov T, Hansen KC. Rapid detection of DEHP in packed red blood cells stored under European and US standard conditions. Blood Transfus. 2016 Mar; 14(2):140-4.
    View in: PubMed
    Score: 0.119
  87. D'Alessandro A, Nemkov T, Hansen KC, Szczepiorkowski ZM, Dumont LJ. Red blood cell storage in additive solution-7 preserves energy and redox metabolism: a metabolomics approach. Transfusion. 2015 Dec; 55(12):2955-66.
    View in: PubMed
    Score: 0.117
  88. D'Alessandro A, Slaughter AL, Peltz ED, Moore EE, Silliman CC, Wither M, Nemkov T, Bacon AW, Fragoso M, Banerjee A, Hansen KC. Trauma/hemorrhagic shock instigates aberrant metabolic flux through glycolytic pathways, as revealed by preliminary (13)C-glucose labeling metabolomics. J Transl Med. 2015 Aug 05; 13:253.
    View in: PubMed
    Score: 0.116
  89. Nemkov T, D'Alessandro A, Hansen KC. Three-minute method for amino acid analysis by UHPLC and high-resolution quadrupole orbitrap mass spectrometry. Amino Acids. 2015 Nov; 47(11):2345-57.
    View in: PubMed
    Score: 0.115
  90. D'Alessandro A, Moore HB, Moore EE, Wither M, Nemkov T, Gonzalez E, Slaughter A, Fragoso M, Hansen KC, Silliman CC, Banerjee A. Early hemorrhage triggers metabolic responses that build up during prolonged shock. Am J Physiol Regul Integr Comp Physiol. 2015 Jun 15; 308(12):R1034-44.
    View in: PubMed
    Score: 0.114
  91. D'Alessandro A, Nemkov T, Kelher M, West FB, Schwindt RK, Banerjee A, Moore EE, Silliman CC, Hansen KC. Routine storage of red blood cell (RBC) units in additive solution-3: a comprehensive investigation of the RBC metabolome. Transfusion. 2015 Jun; 55(6):1155-68.
    View in: PubMed
    Score: 0.112
  92. Patel SB, Moskop DR, Moreira S, Gipson S, Anderson CC, Crook A, McCabe M, Stephenson D, Terry HE, Kent A, Young TN, Krug AE, Thomas CI, Price C, Ransom M, Miller R, Vujovic A, Minhajuddin M, Althoff MJ, Consortium TC, Saviola AJ, Stevens BM, Welner RS, Andrianova EL, Gudkov AV, Darehshouri A, Reisz JA, Nemkov T, D'Alessandro A, Gillen AE, Pollyea DA, Jordan CT, Pietras EM. The Nicotinamide Salvage Pathway is a Metabolic Vulnerability of High-Risk MDS Stem Cells. Blood Cancer Discov. 2026 Jul 21.
    View in: PubMed
    Score: 0.062
  93. Rai M, Shefali SA, Tourigny JP, Kim M, Nemkov T, D'Alessandro A, Tennessen JM. Drosophila melanogaster lactate dehydrogenase deficiency recapitulates the exercise intolerance of human glycogen storage disease type XI. bioRxiv. 2026 Jul 10.
    View in: PubMed
    Score: 0.062
  94. Kilbourn EA, Lowe MR, Panda K, Bhaskaran AM, Zheng G, Aalati AR, Malave A, White S, Graber A, Zulkowski N, Pepin R, Salamova A, Nemkov T, D'Alessandro A, Yadlapalli S, Reddy P, Meyhofer E, Tennessen JM. Exposure to perfluorooctanoic acid accelerates Drosophila melanogaster juvenile development and disrupts mitochondrial metabolism. bioRxiv. 2026 Jun 17.
    View in: PubMed
    Score: 0.062
  95. Smoot SR, Tourigny J, Holsopple-Bowen JM, Fitt AJ, Pena-Garcia Y, Lowe MR, Rose DA, Zolman NC, Thrasher GH, Arya SS, Vires HB, Adams EC, Colbourne JK, Shaw JR, Oliver B, Nemkov T, D'Alessandro A, Kaufman TC, Tennessen JM. Conserved Molecular Responses to Arsenite Exposure in Drosophila melanogaster. bioRxiv. 2026 Feb 10.
    View in: PubMed
    Score: 0.060
  96. Bartram J, Treichel S, Song BA, Xu J, Sharma D, Nasr W, Frangiosa M, Harley A, Nemkov T, D'Alessandro A, Salomonis N, Grimes HL, Filippi MD. Activation of a branched-chain amino acid rheostat restores replication-dependent hematopoietic stem cell fitness. Cell Stem Cell. 2026 Feb 05; 33(2):289-305.e6.
    View in: PubMed
    Score: 0.060
  97. Lindsey ARI, Tennessen JM, Gelaw MA, Jones MW, Parish AJ, Newton ILG, Nemkov T, D'Alessandro A, Rai M, Stark N. The intracellular symbiont Wolbachia alters Drosophila development and metabolism to buffer against nutritional stress. PLoS Genet. 2025 Oct; 21(10):e1011905.
    View in: PubMed
    Score: 0.059
  98. Rai M, Okah P, Shefali SA, Fitt AJ, Shen MZ, Molomjamts M, Pepin R, Nemkov T, D'Alessandro A, Tennessen JM. New alleles of D-2-hydroxyglutarate dehydrogenase enable studies of oncometabolite function in Drosophila melanogaster. G3 (Bethesda). 2025 08 06; 15(8).
    View in: PubMed
    Score: 0.058
  99. Deng X, Di Germanio C, Marques de Menezes EG, Milani P, Stone M, Tanner H, Bakkour SC, Chafets DM, Reese SE, Roubinian NH, Kleinman S, Kanias T, Busch MP, Earley EJ, Page GP, Nemkov T, D'Alessandro A, Norris PJ. Donor genetics and storage conditions influence mitochondrial DNA and extracellular vesicle levels in RBC units. JCI Insight. 2025 Jul 22; 10(14).
    View in: PubMed
    Score: 0.058
  100. Rojas-Sanchez G, Calzada-Martinez J, McMahon B, Petrey AC, Dveksler G, Espino-Solis GP, Esparza O, Hernandez G, Le D, Wartchow EP, Jones K, Ting LH, Jankowski C, Kelher MR, Manco-Johnson M, Feser ML, Deane KD, Nemkov T, D'Alessandro A, Thorburn A, Maycotte P, López JA, Davizon-Castillo P. TNF-a impairs platelet function by inhibiting autophagy and disrupting metabolism via syntaxin 17 downregulation. J Clin Invest. 2025 08 01; 135(15).
    View in: PubMed
    Score: 0.058
  101. Rai M, Okah P, Shefali SA, Fitt AJ, Shen MZ, Molomjamts M, Pepin R, Nemkov T, D'Alessandro A, Tennessen JM. New alleles of D-2-hydroxyglutarate dehydrogenase enable studies of oncometabolite function in Drosophila melanogaster. bioRxiv. 2025 May 22.
    View in: PubMed
    Score: 0.057
  102. Rai M, Li H, Policastro RA, Pepin R, Zentner GE, Nemkov T, D'Alessandro A, Tennessen JM. Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3. PLoS Genet. 2025 May; 21(5):e1011690.
    View in: PubMed
    Score: 0.057
  103. Willett BAS, Thompson SB, Chen V, Dareshouri A, Jackson CL, Brunetti T, D'Alessandro A, Klarquist J, Nemkov T, Kedl RM. Mitochondrial protein OPA1 is required for the expansion of effector CD8 T cells. Cell Rep. 2025 May 27; 44(5):115610.
    View in: PubMed
    Score: 0.057
  104. Forbes LM, Cendali FI, Nemkov T, Bull TM, D'Alessandro A, Rawlinson KE, Roach RC, Subudhi AW, Lahm T, Cornwell WK. Red Blood Cell Metabolic Responses during Acute Hypoxic Exercise in Healthy Adults. Am J Respir Cell Mol Biol. 2025 Apr; 72(4):456-459.
    View in: PubMed
    Score: 0.057
  105. Heidarian Y, Fasteen TD, Mungcal L, Buddika K, Mahmoudzadeh NH, Nemkov T, D'Alessandro A, Tennessen JM. Hypoxia-inducible factor 1a is required to establish the larval glycolytic program in Drosophila melanogaster. Mol Metab. 2025 Mar; 93:102106.
    View in: PubMed
    Score: 0.056
  106. Heidarian Y, Fasteen TD, Mungcal L, Buddika K, Mahmoudzadeh NH, Nemkov T, D'Alessandro A, Tennessen JM. Hypoxia-inducible factor 1a is required to establish the larval glycolytic program in Drosophila melanogaster. bioRxiv. 2025 Jan 08.
    View in: PubMed
    Score: 0.056
  107. Lee E, Saviola A, Bevers S, Redzic JS, Maroney SP, Shaw S, Tamkin E, Fulte S, Nemkov T, Meyer N, D'Alessandro A, Hansen KC, Clark SE, Eisenmesser E. Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection. Protein Sci. 2025 Jan; 34(1):e5253.
    View in: PubMed
    Score: 0.056
  108. Brechbuhl HM, Han A, Paul KV, Nemkov T, Ramachandran S, Ward A, Jacobsen BM, Hansen K, Sartorius CA, D'Alessandro A, Kabos P. Metabolic Switch in Endocrine Resistant Estrogen Receptor Positive Breast Cancer. bioRxiv. 2024 Dec 29.
    View in: PubMed
    Score: 0.056
  109. Kheyfets VO, Sweatt AJ, Zhang H, Nemkov T, Heerdt P, Dzieciatkowska M, Stephenson D, LaCroix IS, D'Alessandro A, Oldham WM, Hansen K, Zamanian RT, Stenmark KR. Identification of candidate biomarkers and molecular networks associated with Pulmonary Arterial Hypertension using machine learning and plasma multi-Omics analysis. medRxiv. 2024 Dec 20.
    View in: PubMed
    Score: 0.056
  110. Dumont LJ, Kelly K, Nemkov T, Leite C, Gresens CJ, Stanley C, D'Alessandro A, Vassallo RR. Platelet storage failure-Metformin as causative agent. Transfusion. 2024 12; 64(12):2405-2409.
    View in: PubMed
    Score: 0.055
  111. Dziewulska-Cronk KH, Reisz JA, Hay AM, Nemkov T, Cendali FI, Issaian A, Lamb DR, Palha MS, Legenzov EA, Kao JPY, Walker LA, Tekwani BL, Buehler PW, D'Alessandro A, Zimring JC. Primaquine-5,6-Orthoquinone Is Directly Hemolytic to Older G6PD Deficient RBCs in a Humanized Mouse Model. J Pharmacol Exp Ther. 2024 09 18; 391(1):119-129.
    View in: PubMed
    Score: 0.055
  112. Kumar S, Vassallo JD, Nattamai KJ, Hassan A, Vollmer A, Karns R, Sacma M, Nemkov T, D'Alessandro A, Geiger H. Rejuvenation of the reconstitution potential and reversal of myeloid bias of aged HSCs upon pH treatment. Aging Cell. 2024 10; 23(10):e14324.
    View in: PubMed
    Score: 0.055
  113. Mahmoudzadeh NH, Heidarian Y, Tourigny JP, Fitt AJ, Beebe K, Li H, Luhur A, Buddika K, Mungcal L, Kundu A, Policastro RA, Brinkley GJ, Zentner GE, Nemkov T, Pepin R, Chawla G, Sudarshan S, Rodan AR, D'Alessandro A, Tennessen JM. Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster. Mol Metab. 2024 Nov; 89:102013.
    View in: PubMed
    Score: 0.055
  114. Rai M, Li H, Policastro RA, Zentner GE, Nemkov T, D'Alessandro A, Tennessen JM. Glycolytic Disruption Triggers Interorgan Signaling to Nonautonomously Restrict Drosophila Larval Growth. bioRxiv. 2024 Jun 09.
    View in: PubMed
    Score: 0.054
  115. Lindsey AR, Tennessen JM, Gelaw MA, Jones MW, Parish AJ, Newton IL, Nemkov T, D'Alessandro A, Rai M, Stark N. The intracellular symbiont Wolbachia alters Drosophila development and metabolism to buffer against nutritional stress. bioRxiv. 2024 May 21.
    View in: PubMed
    Score: 0.054
  116. Fleck SA, Biswas P, DeWitt ED, Knuteson RL, Eisman RC, Nemkov T, D'Alessandro A, Tennessen JM, Rideout E, Weaver LN. Auxin exposure disrupts feeding behavior and fatty acid metabolism in adult Drosophila. Elife. 2024 Jan 19; 12.
    View in: PubMed
    Score: 0.052
  117. Heidarian Y, Tourigny JP, Fasteen TD, Mahmoudzadeh NH, Hurlburt AJ, Nemkov T, Reisz JA, D'Alessandro A, Tennessen JM. Metabolomic analysis of Drosophila melanogaster larvae lacking pyruvate kinase. G3 (Bethesda). 2023 12 29; 14(1).
    View in: PubMed
    Score: 0.052
  118. Fleck SA, Biswas P, DeWitt ED, Knuteson RL, Eisman RC, Nemkov T, D'Alessandro A, Tennessen JM, Rideout EJ, Weaver LN. Auxin Exposure Disrupts Feeding Behavior and Fatty Acid Metabolism in Adult Drosophila. bioRxiv. 2023 Dec 04.
    View in: PubMed
    Score: 0.052
  119. Diaz AV, Stephenson D, Nemkov T, D'Alessandro A, Reis T. Spenito-dependent metabolic sexual dimorphism intrinsic to fat storage cells. Genetics. 2023 11 01; 225(3).
    View in: PubMed
    Score: 0.052
  120. Craighead DH, Freeberg KA, Heinbockel TC, Rossman MJ, Jackman RA, McCarty NP, Jankowski LR, Nemkov T, Reisz JA, D'Alessandro A, Chonchol M, Bailey EF, Seals DR. Time-Efficient, High-Resistance Inspiratory Muscle Strength Training Increases Exercise Tolerance in Midlife and Older Adults. Med Sci Sports Exerc. 2024 02 01; 56(2):266-276.
    View in: PubMed
    Score: 0.051
  121. Heidarian Y, Tourigny JP, Fasteen TD, Mahmoudzadeh NH, Hurlburt AJ, Nemkov T, Reisz JA, D'Alessandro A, Tennessen JM. Metabolomic analysis of Drosophila melanogaster larvae lacking Pyruvate kinase. bioRxiv. 2023 Jun 19.
    View in: PubMed
    Score: 0.050
  122. Bolf EL, Beadnell TC, Rose MM, D'Alessandro A, Nemkov T, Hansen KC, Schweppe RE. Dasatinib and Trametinib Promote Anti-Tumor Metabolic Activity. Cells. 2023 05 12; 12(10).
    View in: PubMed
    Score: 0.050
  123. Esparza O, Hernandez G, Rojas-Sanchez G, Calzada-Martinez J, Nemkov T, Kelher M, Kelly K, Silliman CC, DomBourian M, Dumont LJ, D'Alessandro A, Davizon-Castillo P. Platelets from blood diversion pouches (DPs) are a suitable alternative for functional, bioenergetic, and metabolomic analyses. Blood Transfus. 2023 Mar 31.
    View in: PubMed
    Score: 0.049
  124. Kumar S, Vassallo JD, Nattamai KJ, Hassan A, Karns R, Vollmer A, Soller K, Sakk V, Sacma M, Nemkov T, D'Alessandro A, Geiger H. pH regulates hematopoietic stem cell potential via polyamines. EMBO Rep. 2023 05 04; 24(5):e55373.
    View in: PubMed
    Score: 0.049
  125. Mian SA, Philippe C, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D, Morales V, Finch AJ, D'Alessandro A, Bianchi K, Wang J, Gallipoli P, Kordasti S, Kubasch AS, Cross M, Platzbecker U, Wiseman DH, Bonnet D, Bernard DG, Gribben JG, Rouault-Pierre K. Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia. Sci Transl Med. 2023 03; 15(685):eabn5135.
    View in: PubMed
    Score: 0.049
  126. Diaz AV, Matheny T, Stephenson D, Nemkov T, D'Alessandro A, Reis T. Spenito-dependent metabolic sexual dimorphism intrinsic to fat storage cells. bioRxiv. 2023 Feb 18.
    View in: PubMed
    Score: 0.049
  127. Setua S, Thangaraju K, Dzieciatkowska M, Wilkerson RB, Nemkov T, Lamb DR, Tagaya Y, Boyer T, Rowden T, Doctor A, D'Alessandro A, Buehler PW. Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma. Sci Rep. 2022 12 23; 12(1):22191.
    View in: PubMed
    Score: 0.049
  128. Nikulina M, Nemkov T, D'Alessandro A, Gaccione P, Yoshida T. A deep 96-well plate RBC storage platform for high-throughput screening of novel storage solutions. Front Physiol. 2022; 13:1004936.
    View in: PubMed
    Score: 0.048
  129. Lee E, Redzic JS, Nemkov T, Saviola AJ, Dzieciatkowska M, Hansen KC, D'Alessandro A, Dinarello C, Eisenmesser EZ. Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Molecules. 2022 Jul 14; 27(14).
    View in: PubMed
    Score: 0.047
  130. Guard SE, Chapnick DA, Poss ZC, Ebmeier CC, Jacobsen J, Nemkov T, Ball KA, Webb KJ, Simpson HL, Coleman S, Bunker E, Ramirez A, Reisz JA, Sievers R, Stowell MHB, D'Alessandro A, Liu X, Old WM. Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines. Mol Cell Proteomics. 2022 10; 21(10):100262.
    View in: PubMed
    Score: 0.047
  131. Patel SB, Nemkov T, D'Alessandro A, Welner RS. Deciphering Metabolic Adaptability of Leukemic Stem Cells. Front Oncol. 2022; 12:846149.
    View in: PubMed
    Score: 0.047
  132. Ferrero E, Villa A, Stefanoni D, Nemkov T, D'Alessandro A, Tengesdal I, Belloni D, Molteni R, Vergani B, De Luca G, Grassini G, Cangi MG, Dagna L, Doglioni C, Cavalli G, Ferrarini M. Immunometabolic activation of macrophages leads to cytokine production in the pathogenesis of KRAS-mutated histiocytosis. Rheumatology (Oxford). 2022 04 11; 61(4):e93-e96.
    View in: PubMed
    Score: 0.046
  133. Thangaraju K, Katneni U, Akpan IJ, Tanaka K, Thomas T, Setua S, Reisz JA, Cendali F, Gamboni F, Nemkov T, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh DJ, Moriconi C, Zimring JC, D'Alessandro A, Spitalnik SL, Francis RO, Buehler PW. The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 Patients. Front Med (Lausanne). 2021; 8:817305.
    View in: PubMed
    Score: 0.045
  134. Molteni R, Biavasco R, Stefanoni D, Nemkov T, Domínguez-Andrés J, Arts RJ, Merelli I, Mazza D, Zambrano S, Panigada M, Cantoni E, Tengesdal IW, Maksud P, Piras F, Cesana D, Cassina L, Distefano G, Loffreda A, Gnani D, De Luca G, Tomelleri A, Campochiaro C, Joosten LAB, Dinarello CA, Kajaste-Rudnitski A, Haroche J, Cardaci S, Cenci S, Dagna L, Doglioni C, Ferrarini M, Ferrero E, Boletta A, D'Alessandro A, Montini E, Netea MG, Cavalli G. Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease. Blood. 2021 10 28; 138(17):1554-1569.
    View in: PubMed
    Score: 0.045
  135. Robert M, Laperrousaz B, Piedrahita D, Gautier EF, Nemkov T, Dupuy F, Nader E, Salnot V, Mayeux P, D'Alessandro A, Lavazec C, Joly P, Scheer A, Connes P, Cibiel A. Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process. Acta Pharm Sin B. 2022 Apr; 12(4):2089-2102.
    View in: PubMed
    Score: 0.045
  136. Bissinger R, Nemkov T, D'Alessandro A, Grau M, Dietz T, Bohnert BN, Essigke D, Wörn M, Schaefer L, Xiao M, Beirne JM, Kalo MZ, Schork A, Bakchoul T, Omage K, Kong L, Gonzalez-Menendez I, Quintanilla-Martinez L, Fehrenbacher B, Schaller M, Dhariwal A, Birkenfeld AL, Grahammer F, Qadri SM, Artunc F. Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism. Kidney Int. 2021 12; 100(6):1227-1239.
    View in: PubMed
    Score: 0.044
  137. Qiang Q, Manalo JM, Sun H, Zhang Y, Song A, Wen AQ, Wen YE, Chen C, Liu H, Cui Y, Nemkov T, Reisz JA, Edwards Iii G, Perreira FA, Kellems RE, Soto C, D'Alessandro A, Xia Y. Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming. PLoS Biol. 2021 06; 19(6):e3001239.
    View in: PubMed
    Score: 0.044
  138. Patel SB, Nemkov T, Stefanoni D, Benavides GA, Bassal MA, Crown BL, Matkins VR, Camacho V, Kuznetsova V, Hoang AT, Tenen DE, Wolock SL, Park J, Ying L, Yue Z, Chen JY, Yang H, Tenen DG, Ferrell PB, Lu R, Darley-Usmar V, D'Alessandro A, Bhatia R, Welner RS. Metabolic alterations mediated by STAT3 promotes drug persistence in CML. Leukemia. 2021 12; 35(12):3371-3382.
    View in: PubMed
    Score: 0.044
  139. Sackheim AM, Villalba N, Sancho M, Harraz OF, Bonev AD, D'Alessandro A, Nemkov T, Nelson MT, Freeman K. Traumatic Brain Injury Impairs Systemic Vascular Function Through Disruption of Inward-Rectifier Potassium Channels. Function (Oxf). 2021; 2(3).
    View in: PubMed
    Score: 0.043
  140. Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, Dagna L, Boletta A, D'Alessandro A, Joosten LAB, Netea MG, Dinarello CA. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity. Cell Rep. 2021 04 06; 35(1):108955.
    View in: PubMed
    Score: 0.043
  141. Li M, Riddle S, Kumar S, Poczobutt J, McKeon BA, Frid MG, Ostaff M, Reisz JA, Nemkov T, Fini MA, Laux A, Hu CJ, El Kasmi KC, D'Alessandro A, Brown RD, Zhang H, Stenmark KR. Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension. Front Immunol. 2021; 12:640718.
    View in: PubMed
    Score: 0.043
  142. Esquer H, Zhou Q, Nemkov T, Abraham AD, Rinaldetti S, Chen YC, Zhang X, Orman MV, D'Alessandro A, Ferrer M, Messersmith WA, LaBarbera DV. Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer. Oncogene. 2021 04; 40(16):2884-2897.
    View in: PubMed
    Score: 0.043
  143. Broussard JL, Perreault L, Macias E, Newsom SA, Harrison K, Bui HH, Milligan P, Roth KD, Nemkov T, D'Alessandro A, Brozinick JT, Bergman BC. Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. Obesity (Silver Spring). 2021 03; 29(3):550-561.
    View in: PubMed
    Score: 0.043
  144. Henriksen HH, McGarrity S, SigurÐardóttir RS, Nemkov T, D'Alessandro A, Palsson BO, Stensballe J, Wade CE, Rolfsson Ó, Johansson PI. Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma: A New Research Paradigm. Ann Surg. 2020 12; 272(6):1140-1148.
    View in: PubMed
    Score: 0.042
  145. Jones CL, Stevens BM, Pollyea DA, Culp-Hill R, Reisz JA, Nemkov T, Gehrke S, Gamboni F, Krug A, Winters A, Pei S, Gustafson A, Ye H, Inguva A, Amaya M, Minhajuddin M, Abbott D, Becker MW, DeGregori J, Smith CA, D'Alessandro A, Jordan CT. Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells. Cell Stem Cell. 2020 11 05; 27(5):748-764.e4.
    View in: PubMed
    Score: 0.041
  146. Stefanoni D, Fu X, Reisz JA, Kanias T, Nemkov T, Page GP, Dumont L, Roubinian N, Stone M, Kleinman S, Busch M, Zimring JC, D'Alessandro A. Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers. Transfusion. 2020 06; 60(6):1160-1174.
    View in: PubMed
    Score: 0.040
  147. Francis RO, D'Alessandro A, Eisenberger A, Soffing M, Yeh R, Coronel E, Sheikh A, Rapido F, La Carpia F, Reisz JA, Gehrke S, Nemkov T, Thomas T, Schwartz J, Divgi C, Kessler D, Shaz BH, Ginzburg Y, Zimring JC, Spitalnik SL, Hod EA. Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion. J Clin Invest. 2020 05 01; 130(5):2270-2285.
    View in: PubMed
    Score: 0.040
  148. Williams AT, Jani VP, Nemkov T, Lucas A, Yoshida T, Dunham A, D'Alessandro A, Cabrales P. Transfusion of Anaerobically or Conventionally Stored Blood After Hemorrhagic Shock. Shock. 2020 03; 53(3):352-362.
    View in: PubMed
    Score: 0.040
  149. Gillette CM, Hazegh KE, Nemkov T, Stefanoni D, D'Alessandro A, Taliaferro JM, Reis T. Gene-Diet Interactions: Dietary Rescue of Metabolic Effects in spen-Depleted Drosophila melanogaster. Genetics. 2020 04; 214(4):961-975.
    View in: PubMed
    Score: 0.040
  150. Pei S, Pollyea DA, Gustafson A, Stevens BM, Minhajuddin M, Fu R, Riemondy KA, Gillen AE, Sheridan RM, Kim J, Costello JC, Amaya ML, Inguva A, Winters A, Ye H, Krug A, Jones CL, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers JR, Ashton JM, Nemkov T, D'Alessandro A, Gutman JA, Ramsey HE, Savona MR, Smith CA, Jordan CT. Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia. Cancer Discov. 2020 04; 10(4):536-551.
    View in: PubMed
    Score: 0.040
  151. Abraham AD, Esquer H, Zhou Q, Tomlinson N, Hamill BD, Abbott JM, Li L, Pike LA, Rinaldetti S, Ramirez DA, Lunghofer PJ, Gomez JD, Schaack J, Nemkov T, D'Alessandro A, Hansen KC, Gustafson DL, Messersmith WA, LaBarbera DV. Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer. J Med Chem. 2019 11 27; 62(22):10182-10203.
    View in: PubMed
    Score: 0.039
  152. Johnson LC, Parker K, Aguirre BF, Nemkov TG, D'Alessandro A, Johnson SA, Seals DR, Martens CR. The plasma metabolome as a predictor of biological aging in humans. Geroscience. 2019 12; 41(6):895-906.
    View in: PubMed
    Score: 0.039
  153. Nohara K, Nemkov T, D'Alessandro A, Yoo SH, Chen Z. Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice. Int J Mol Sci. 2019 Sep 01; 20(17).
    View in: PubMed
    Score: 0.039
  154. Nohara K, Mallampalli V, Nemkov T, Wirianto M, Yang J, Ye Y, Sun Y, Han L, Esser KA, Mileykovskaya E, D'Alessandro A, Green CB, Takahashi JS, Dowhan W, Yoo SH, Chen Z. Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge. Nat Commun. 2019 08 28; 10(1):3923.
    View in: PubMed
    Score: 0.039
  155. Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. TNF-a-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Blood. 2019 08 29; 134(9):727-740.
    View in: PubMed
    Score: 0.038
  156. Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J. Targeting Glutamine Metabolism and Redox State for Leukemia Therapy. Clin Cancer Res. 2019 07 01; 25(13):4079-4090.
    View in: PubMed
    Score: 0.038
  157. Jones CL, Stevens BM, D'Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Adane B, Ye H, Krug A, Reinhold D, Smith C, DeGregori J, Pollyea DA, Jordan CT. Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells. Cancer Cell. 2019 Feb 11; 35(2):333-335.
    View in: PubMed
    Score: 0.037
  158. Rogers SC, Dosier LB, McMahon TJ, Zhu H, Timm D, Zhang H, Herbert J, Atallah J, Palmer GM, Cook A, Ernst M, Prakash J, Terng M, Towfighi P, Doctor R, Said A, Joens MS, Fitzpatrick JAJ, Hanna G, Lin X, Reisz JA, Nemkov T, D'Alessandro A, Doctor A. Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes. PLoS One. 2018; 13(12):e0209201.
    View in: PubMed
    Score: 0.037
  159. Clendenen N, Nunns GR, Moore EE, Gonzalez E, Chapman M, Reisz JA, Peltz E, Fragoso M, Nemkov T, Wither MJ, Sauaia A, Silliman CC, Hansen K, Banerjee A, D'Alessandro A, Moore HB. Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements. Blood Transfus. 2019 09; 17(5):347-356.
    View in: PubMed
    Score: 0.037
  160. Jones CL, Stevens BM, D'Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Adane B, Ye H, Krug A, Reinhold D, Smith C, DeGregori J, Pollyea DA, Jordan CT. Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells. Cancer Cell. 2018 11 12; 34(5):724-740.e4.
    View in: PubMed
    Score: 0.037
  161. Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM. Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2018 10; 59(4):479-489.
    View in: PubMed
    Score: 0.036
  162. Wesolowski SR, Mulligan CM, Janssen RC, Baker PR, Bergman BC, D'Alessandro A, Nemkov T, Maclean KN, Jiang H, Dean TA, Takahashi DL, Kievit P, McCurdy CE, Aagaard KM, Friedman JE. Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates. Mol Metab. 2018 12; 18:25-41.
    View in: PubMed
    Score: 0.036
  163. Rogers TJ, Christenson JL, Greene LI, O'Neill KI, Williams MM, Gordon MA, Nemkov T, D'Alessandro A, Degala GD, Shin J, Tan AC, Cittelly DM, Lambert JR, Richer JK. Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression. Mol Cancer Res. 2019 01; 17(1):30-41.
    View in: PubMed
    Score: 0.036
  164. Stevens BM, Khan N, D'Alessandro A, Nemkov T, Winters A, Jones CL, Zhang W, Pollyea DA, Jordan CT. Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes. Nat Commun. 2018 09 12; 9(1):3694.
    View in: PubMed
    Score: 0.036
  165. Slaughter AL, Nunns GR, D'Alessandro A, Banerjee A, Hansen KC, Moore EE, Silliman CC, Nemkov T, Moore HB, Fragoso M, Leasia K, Peltz ED. The Metabolopathy of Tissue Injury, Hemorrhagic Shock, and Resuscitation in a Rat Model. Shock. 2018 05; 49(5):580-590.
    View in: PubMed
    Score: 0.035
  166. Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem. 2018 05 04; 293(18):6659-6671.
    View in: PubMed
    Score: 0.035
  167. Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T. Correction: An autonomous metabolic role for Spen. PLoS Genet. 2018 03; 14(3):e1007266.
    View in: PubMed
    Score: 0.035
  168. Perreault L, Newsom SA, Strauss A, Kerege A, Kahn DE, Harrison KA, Snell-Bergeon JK, Nemkov T, D'Alessandro A, Jackman MR, MacLean PS, Bergman BC. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle. JCI Insight. 2018 02 08; 3(3).
    View in: PubMed
    Score: 0.035
  169. Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1530-E1539.
    View in: PubMed
    Score: 0.035
  170. Reisz JA, Tzounakas VL, Nemkov T, Voulgaridou AI, Papassideri IS, Kriebardis AG, D'Alessandro A, Antonelou MH. Metabolic Linkage and Correlations to Storage Capacity in Erythrocytes from Glucose 6-Phosphate Dehydrogenase-Deficient Donors. Front Med (Lausanne). 2017; 4:248.
    View in: PubMed
    Score: 0.034
  171. Sun K, D'Alessandro A, Ahmed MH, Zhang Y, Song A, Ko TP, Nemkov T, Reisz JA, Wu H, Adebiyi M, Peng Z, Gong J, Liu H, Huang A, Wen YE, Wen AQ, Berka V, Bogdanov MV, Abdulmalik O, Han L, Tsai AL, Idowu M, Juneja HS, Kellems RE, Dowhan W, Hansen KC, Safo MK, Xia Y. Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Sci Rep. 2017 11 10; 7(1):15281.
    View in: PubMed
    Score: 0.034
  172. Gregory MA, Nemkov T, Reisz JA, Zaberezhnyy V, Hansen KC, D'Alessandro A, DeGregori J. Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia. Exp Hematol. 2018 02; 58:52-58.
    View in: PubMed
    Score: 0.034
  173. Henry CJ, Nemkov T, Casás-Selves M, Bilousova G, Zaberezhnyy V, Higa KC, Serkova NJ, Hansen KC, D'Alessandro A, DeGregori J. Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis. Haematologica. 2017 12; 102(12):1985-1994.
    View in: PubMed
    Score: 0.034
  174. Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T. An autonomous metabolic role for Spen. PLoS Genet. 2017 Jun; 13(6):e1006859.
    View in: PubMed
    Score: 0.033
  175. Yoshida T, Blair A, D'alessandro A, Nemkov T, Dioguardi M, Silliman CC, Dunham A. Enhancing uniformity and overall quality of red cell concentrate with anaerobic storage. Blood Transfus. 2017 Mar; 15(2):172-181.
    View in: PubMed
    Score: 0.032
  176. Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2313-2318.
    View in: PubMed
    Score: 0.032
  177. Song A, Zhang Y, Han L, Yegutkin GG, Liu H, Sun K, D'Alessandro A, Li J, Karmouty-Quintana H, Iriyama T, Weng T, Zhao S, Wang W, Wu H, Nemkov T, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Hansen KC, Zhang H, Bogdanov M, Dowhan W, Jin J, Kellems RE, Eltzschig HK, Blackburn M, Roach RC, Xia Y. Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017 02 07; 8:14108.
    View in: PubMed
    Score: 0.032
  178. Kendrick AA, Schafer J, Dzieciatkowska M, Nemkov T, D'Alessandro A, Neelakantan D, Ford HL, Pearson CG, Weekes CD, Hansen KC, Eisenmesser EZ. CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. Oncotarget. 2017 Jan 24; 8(4):6742-6762.
    View in: PubMed
    Score: 0.032
  179. Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P. The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis. Cancer Discov. 2017 02; 7(2):177-187.
    View in: PubMed
    Score: 0.032
  180. Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):E6669-E6678.
    View in: PubMed
    Score: 0.032
  181. Gamboni F, Anderson C, Mitra S, Reisz JA, Nemkov T, Dzieciatkowska M, Jones KL, Hansen KC, D'Alessandro A, Banerjee A. Hypertonic Saline Primes Activation of the p53-p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines. J Proteome Res. 2016 10 07; 15(10):3813-3826.
    View in: PubMed
    Score: 0.031
  182. Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells. J Biol Chem. 2016 Oct 14; 291(42):21984-22000.
    View in: PubMed
    Score: 0.031
  183. Paglia G, D'Alessandro A, Rolfsson Ó, Sigurjónsson ÓE, Bordbar A, Palsson S, Nemkov T, Hansen KC, Gudmundsson S, Palsson BO. Biomarkers defining the metabolic age of red blood cells during cold storage. Blood. 2016 09 29; 128(13):e43-50.
    View in: PubMed
    Score: 0.031
  184. Liu H, Zhang Y, Wu H, D'Alessandro A, Yegutkin GG, Song A, Sun K, Li J, Cheng NY, Huang A, Edward Wen Y, Weng TT, Luo F, Nemkov T, Sun H, Kellems RE, Karmouty-Quintana H, Hansen KC, Zhao B, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia. Circulation. 2016 Aug 02; 134(5):405-21.
    View in: PubMed
    Score: 0.031
  185. Sun K, Zhang Y, D'Alessandro A, Nemkov T, Song A, Wu H, Liu H, Adebiyi M, Huang A, Wen YE, Bogdanov MV, Vila A, O'Brien J, Kellems RE, Dowhan W, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Safo M, Hansen KC, Roach RC, Xia Y. Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia. Nat Commun. 2016 07 15; 7:12086.
    View in: PubMed
    Score: 0.031
  186. Tzounakas VL, Kriebardis AG, Georgatzakou HT, Foudoulaki-Paparizos LE, Dzieciatkowska M, Wither MJ, Nemkov T, Hansen KC, Papassideri IS, D'Alessandro A, Antonelou MH. Data on how several physiological parameters of stored red blood cells are similar in glucose 6-phosphate dehydrogenase deficient and sufficient donors. Data Brief. 2016 Sep; 8:618-27.
    View in: PubMed
    Score: 0.031
  187. Tzounakas VL, Kriebardis AG, Georgatzakou HT, Foudoulaki-Paparizos LE, Dzieciatkowska M, Wither MJ, Nemkov T, Hansen KC, Papassideri IS, D'Alessandro A, Antonelou MH. Glucose 6-phosphate dehydrogenase deficient subjects may be better "storers" than donors of red blood cells. Free Radic Biol Med. 2016 07; 96:152-65.
    View in: PubMed
    Score: 0.031
  188. Newsom SA, Brozinick JT, Kiseljak-Vassiliades K, Strauss AN, Bacon SD, Kerege AA, Bui HH, Sanders P, Siddall P, Wei T, Thomas M, Kuo MS, Nemkov T, D'Alessandro A, Hansen KC, Perreault L, Bergman BC. Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans. J Appl Physiol (1985). 2016 Jun 01; 120(11):1355-63.
    View in: PubMed
    Score: 0.030
  189. Wither M, Dzieciatkowska M, Nemkov T, Strop P, D'Alessandro A, Hansen KC. Hemoglobin oxidation at functional amino acid residues during routine storage of red blood cells. Transfusion. 2016 Feb; 56(2):421-6.
    View in: PubMed
    Score: 0.029
  190. D'Amato NC, Rogers TJ, Gordon MA, Greene LI, Cochrane DR, Spoelstra NS, Nemkov TG, D'Alessandro A, Hansen KC, Richer JK. A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer. Cancer Res. 2015 Nov 01; 75(21):4651-64.
    View in: PubMed
    Score: 0.029
  191. Mosher J, Zhang W, Blumhagen RZ, D'Alessandro A, Nemkov T, Hansen KC, Hesselberth JR, Reis T. Coordination between Drosophila Arc1 and a specific population of brain neurons regulates organismal fat. Dev Biol. 2015 Sep 15; 405(2):280-90.
    View in: PubMed
    Score: 0.029
  192. Hill RC, Wither MJ, Nemkov T, Barrett A, D'Alessandro A, Dzieciatkowska M, Hansen KC. Preserved Proteins from Extinct Bison latifrons Identified by Tandem Mass Spectrometry; Hydroxylysine Glycosides are a Common Feature of Ancient Collagen. Mol Cell Proteomics. 2015 Jul; 14(7):1946-58.
    View in: PubMed
    Score: 0.029
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)