Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Angelo D'Alessandro to Humans

This is a "connection" page, showing publications Angelo D'Alessandro has written about Humans.

 
Connection Strength
 
 
 
3.176
 
  1. D'Alessandro A, Zimring JC. From metabolomics to transfusion-associated immunomodulation. Curr Opin Immunol. 2025 Oct; 96:102646.
    View in: PubMed
    Score: 0.024
  2. Karafin MS, Grier AL, Fasano RM, Ilich A, Wichlan D, Chang A, James SM, Butler HE, Kolupaev O, Caughey MC, Stephenson DJ, Reisz JA, Key NS, Field JJ, Little JA, Spitalnik SL, D'Alessandro A. Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions. J Clin Invest. 2025 Sep 02; 135(17).
    View in: PubMed
    Score: 0.024
  3. Fortis SP, Grier AL, Reisz JA, Dzieciatkowska M, Cendali FI, Kauffman V, Morton DH, D'Alessandro A. Advancing the Biochemical Understanding of Maple Syrup Urine Disease and the Impact of Liver Transplantation: A Pilot Study. J Proteome Res. 2025 Jun 06; 24(6):3088-3104.
    View in: PubMed
    Score: 0.024
  4. D'Alessandro A. Red blood cell metabolism: a window on systems health towards clinical metabolomics. Curr Opin Hematol. 2025 May 01; 32(3):111-119.
    View in: PubMed
    Score: 0.023
  5. D'Alessandro A, Keele GR, Hay A, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman S, Spitalnik SL, Roubinian N, Norris PJ, Busch MP, Page GP, Stockwell BR, Churchill GA, Zimring JC. Ferroptosis regulates hemolysis in stored murine and human red blood cells. Blood. 2025 Feb 13; 145(7):765-783.
    View in: PubMed
    Score: 0.023
  6. Cendali FI, Lisk C, Dzieciatkowska M, LaCroix IS, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow EP, Darehshouri A, Dziewulska-Cronk KH, Buehler PW, Norris PJ, Deng X, Busch MP, Earley EJ, Page GP, Hansen KC, Zimring JC, Irwin DC, Nemkov T, D'Alessandro A. Increased exercise tolerance in humanized G6PD-deficient mice. Blood Adv. 2025 Jan 28; 9(2):321-334.
    View in: PubMed
    Score: 0.023
  7. Key AM, Earley EJ, Tzounakas VL, Anastasiadi AT, Nemkov T, Stephenson D, Dzieciatkowska M, Reisz JA, Keele GR, Deng X, Stone M, Kleinman S, Hansen KC, Norris PJ, Busch MP, Roubinian NH, Page GP, D'Alessandro A. Red blood cell urate levels are linked to hemolysis in vitro and post-transfusion as a function of donor sex, population and genetic polymorphisms in SLC2A9 and ABCG2. Transfusion. 2025 Mar; 65(3):560-574.
    View in: PubMed
    Score: 0.023
  8. Reisz JA, Earley EJ, Nemkov T, Key A, Stephenson D, Keele GR, Dzieciatkowska M, Spitalnik SL, Hod EA, Kleinman S, Roubinian NH, Gladwin MT, Hansen KC, Norris PJ, Busch MP, Zimring JC, Churchill GA, Page GP, D'Alessandro A. Arginine metabolism is a biomarker of red blood cell and human aging. Aging Cell. 2025 Feb; 24(2):e14388.
    View in: PubMed
    Score: 0.023
  9. D'Alessandro A. It's in your blood: The impact of age, sex, genetic factors and exposures on stored red blood cell metabolism. Transfus Apher Sci. 2024 12; 63(6):104011.
    View in: PubMed
    Score: 0.023
  10. D'Alessandro A, Le K, Lundt M, Li Q, Dunkelberger EB, Cellmer T, Worth AJ, Patil S, Huston C, Grier A, Dzieciatkowska M, Stephenson D, Eaton WA, Thein SL. Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease. Haematologica. 2024 08 01; 109(8):2639-2652.
    View in: PubMed
    Score: 0.022
  11. Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman ZB, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A. Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes. Cell Metab. 2024 Sep 03; 36(9):1979-1997.e13.
    View in: PubMed
    Score: 0.022
  12. Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro. Blood. 2024 06 13; 143(24):2517-2533.
    View in: PubMed
    Score: 0.022
  13. D'Alessandro A. Heavy metals in red blood cells: From "Iron Maiden" to "Lead" Zeppelin. Transfusion. 2024 07; 64(7):1181-1183.
    View in: PubMed
    Score: 0.022
  14. LaCroix IS, Moore EE, Cralley A, Cendali FI, Dzieciatkowska M, Hom P, Mitra S, Cohen M, Silliman C, Hansen KC, D'Alessandro A. Multiomics Signatures of Coagulopathy in a Polytrauma Swine Model Contrasted with Severe Multisystem Injured Patients. J Proteome Res. 2024 04 05; 23(4):1163-1173.
    View in: PubMed
    Score: 0.022
  15. Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife T, Kleinman S, Zimring JC, Roubinian N, Hansen KC, Busch MP, Norris PJ, D'Alessandro A. Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo. Blood. 2024 02 01; 143(5):456-472.
    View in: PubMed
    Score: 0.022
  16. D'Alessandro A, Earley EJ, Nemkov T, Stephenson D, Dzieciatkowska M, Hansen KC, Minetti G, Champigneulle B, Stauffer E, Pichon A, Furian M, Verges S, Kleinman S, Norris PJ, Busch MP, Page GP, Kaestner L. Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude. Proc Natl Acad Sci U S A. 2024 Jan 02; 121(1):e2315930120.
    View in: PubMed
    Score: 0.022
  17. D'Alessandro A, Nouraie SM, Zhang Y, Cendali F, Gamboni F, Reisz JA, Zhang X, Bartsch KW, Galbraith MD, Espinosa JM, Gordeuk VR, Gladwin MT. Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients as a function of therapeutic transfusion and hydroxyurea treatment. Haematologica. 2023 12 01; 108(12):3418-3432.
    View in: PubMed
    Score: 0.021
  18. Schaid TR, LaCroix I, Cohen MJ, Hansen KC, Moore EE, Sauaia A, Cralley AL, Thielen O, Hallas W, Erickson C, Mitra S, Dzieciatkowska M, Silliman CC, D'Alessandro A. METABOLOMIC AND PROTEOMIC CHANGES IN TRAUMA-INDUCED HYPOCALCEMIA. Shock. 2023 11 01; 60(5):652-663.
    View in: PubMed
    Score: 0.021
  19. Roy MK, Wilkerson RB, Alexander K, Nokoff NJ, Cree-Green M, D'Alessandro A. Longitudinal metabolic study of red blood cells from patients undergoing gender-affirming testosterone therapy. Blood Adv. 2023 08 22; 7(16):4269-4277.
    View in: PubMed
    Score: 0.021
  20. D'Alessandro A, Hod EA. Red Blood Cell Storage: From Genome to Exposome Towards Personalized Transfusion Medicine. Transfus Med Rev. 2023 10; 37(4):150750.
    View in: PubMed
    Score: 0.021
  21. LaCroix IS, Cohen M, Moore EE, Dzieciatkowska M, Silliman CC, Hansen KC, D'Alessandro A. Omics markers of platelet transfusion in trauma patients. Transfusion. 2023 08; 63(8):1447-1462.
    View in: PubMed
    Score: 0.021
  22. Skinner SC, Nemkov T, Diaw M, Mbaye MN, Diedhiou D, Sow D, Gueye F, Lopez P, Connes P, D'Alessandro A. Metabolic Profile of Individuals with and without Type 2 Diabetes from Sub-Saharan Africa. J Proteome Res. 2023 07 07; 22(7):2319-2326.
    View in: PubMed
    Score: 0.021
  23. D'Alessandro A, Lukens JR, Zimring JC. The role of PIMT in Alzheimer's disease pathogenesis: A novel hypothesis. Alzheimers Dement. 2023 11; 19(11):5296-5302.
    View in: PubMed
    Score: 0.021
  24. Nemkov T, Cendali F, Stefanoni D, Martinez JL, Hansen KC, San-Millán I, D'Alessandro A. Metabolic Signatures of Performance in Elite World Tour Professional Male Cyclists. Sports Med. 2023 08; 53(8):1651-1665.
    View in: PubMed
    Score: 0.021
  25. Hay A, Nemkov T, Gamboni F, Dzieciatkowska M, Key A, Galbraith M, Bartsch K, Sun K, Xia Y, Stone M, Busch MP, Norris PJ, Zimring JC, D'Alessandro A. Sphingosine 1-phosphate has a negative effect on RBC storage quality. Blood Adv. 2023 04 25; 7(8):1379-1393.
    View in: PubMed
    Score: 0.021
  26. D'Alessandro A, Nouraie SM, Zhang Y, Cendali F, Gamboni F, Reisz JA, Zhang X, Bartsch KW, Galbraith MD, Gordeuk VR, Gladwin MT. In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction. Am J Hematol. 2023 07; 98(7):1017-1028.
    View in: PubMed
    Score: 0.021
  27. LaCroix IS, Cohen M, Moore EE, Dzieciatkowska M, Nemkov T, Schaid TR, Debot M, Jones K, Silliman CC, Hansen KC, D'Alessandro A. Omics Markers of Red Blood Cell Transfusion in Trauma. Int J Mol Sci. 2022 Nov 10; 23(22).
    View in: PubMed
    Score: 0.020
  28. Hay A, Dziewulska K, Gamboni F, Nerguizian D, Dzieciatkowska M, Zimring JC, D'Alessandro A. Hypoxic storage of murine red blood cells improves energy metabolism and post-transfusion recoveries. Blood Transfus. 2023 01; 21(1):50-61.
    View in: PubMed
    Score: 0.020
  29. Lima G, Shurlock J, Wang G, Karanikolou A, Sutehall S, Pitsiladis YP, D'Alessandro A. Metabolomic Profiling of Recombinant Erythropoietin (rHuEpo) in Trained Caucasian Athletes. Clin J Sport Med. 2023 09 01; 33(5):e123-e134.
    View in: PubMed
    Score: 0.020
  30. Miglio A, Maslanka M, Di Tommaso M, Rocconi F, Nemkov T, Buehler PW, Antognoni MT, Spitalnik SL, D'Alessandro A. ZOOMICS : comparative metabolomics of red blood cells from dogs, cows, horses and donkeys during refrigerated storage for up to 42 days. Blood Transfus. 2023 07; 21(4):314-326.
    View in: PubMed
    Score: 0.020
  31. Catala A, Stone M, Busch MP, D'Alessandro A. Reprogramming of red blood cell metabolism in Zika virus-infected donors. Transfusion. 2022 05; 62(5):1045-1064.
    View in: PubMed
    Score: 0.019
  32. Stotts MJ, Risbano MG, Gorham JD, D'Alessandro A. Red blood transfusion as a potential source for false-positive phosphatidylethanol levels. Transfusion. 2022 02; 62(2):506-508.
    View in: PubMed
    Score: 0.019
  33. Kalani Roy M, La Carpia F, Cendali F, Fernando S, Moriconi C, Wojczyk BS, Wang L, Nemkov T, Hod EA, D'Alessandro A. Irradiation Causes Alterations of Polyamine, Purine, and Sulfur Metabolism in Red Blood Cells and Multiple Organs. J Proteome Res. 2022 02 04; 21(2):519-534.
    View in: PubMed
    Score: 0.019
  34. Issaian A, Hay A, Dzieciatkowska M, Roberti D, Perrotta S, Darula Z, Redzic J, Busch MP, Page GP, Rogers SC, Doctor A, Hansen KC, Eisenmesser EZ, Zimring JC, D'Alessandro A. The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality. Haematologica. 2021 Nov 01; 106(11):2971-2985.
    View in: PubMed
    Score: 0.019
  35. D'Alessandro A, Thomas T, Akpan IJ, Reisz JA, Cendali FI, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh D, Moriconi C, Zimring JC, Hod EA, Spitalnik SL, Buehler PW, Francis RO. Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Cells. 2021 09 02; 10(9).
    View in: PubMed
    Score: 0.018
  36. D'Alessandro A, Howie HL, Hay AM, Dziewulska KH, Brown BC, Wither MJ, Karafin M, Stone EF, Spitalnik SL, Hod EA, Francis RO, Fu X, Thomas T, Zimring JC. Hematologic and systemic metabolic alterations due to Mediterranean class II G6PD deficiency in mice. JCI Insight. 2021 07 22; 6(14).
    View in: PubMed
    Score: 0.018
  37. D'Alessandro A, Fu X, Kanias T, Reisz JA, Culp-Hill R, Guo Y, Gladwin MT, Page G, Kleinman S, Lanteri M, Stone M, Busch MP, Zimring JC. Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity. Haematologica. 2021 05 01; 106(5):1290-1302.
    View in: PubMed
    Score: 0.018
  38. Thomas T, Cendali F, Fu X, Gamboni F, Morrison EJ, Beirne J, Nemkov T, Antonelou MH, Kriebardis A, Welsby I, Hay A, Dziewulska KH, Busch MP, Kleinman S, Buehler PW, Spitalnik SL, Zimring JC, D'Alessandro A. Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality. Transfusion. 2021 06; 61(6):1867-1883.
    View in: PubMed
    Score: 0.018
  39. Morgell A, Reisz JA, Ateeb Z, Davanian H, Reinsbach SE, Halimi A, Gaiser R, Valente R, Arnelo U, Del Chiaro M, Chen MS, D'Alessandro A. Metabolic Characterization of Plasma and Cyst Fluid from Cystic Precursors to Pancreatic Cancer Patients Reveal Metabolic Signatures of Bacterial Infection. J Proteome Res. 2021 05 07; 20(5):2725-2738.
    View in: PubMed
    Score: 0.018
  40. Nemkov T, Skinner SC, Nader E, Stefanoni D, Robert M, Cendali F, Stauffer E, Cibiel A, Boisson C, Connes P, D'Alessandro A. Acute Cycling Exercise Induces Changes in Red Blood Cell Deformability and Membrane Lipid Remodeling. Int J Mol Sci. 2021 Jan 18; 22(2).
    View in: PubMed
    Score: 0.018
  41. D'Alessandro A. Benford's law and metabolomics: A tale of numbers and blood. Transfus Apher Sci. 2020 Dec; 59(6):103019.
    View in: PubMed
    Score: 0.017
  42. Thomas T, Stefanoni D, Dzieciatkowska M, Issaian A, Nemkov T, Hill RC, Francis RO, Hudson KE, Buehler PW, Zimring JC, Hod EA, Hansen KC, Spitalnik SL, D'Alessandro A. Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients. J Proteome Res. 2020 11 06; 19(11):4455-4469.
    View in: PubMed
    Score: 0.017
  43. D'Alessandro A, Stefanoni D, Slichter SJ, Fu X, Zimring JC. The impact of donor sex and age on stored platelet metabolism and post-transfusion recovery. Blood Transfus. 2021 05; 19(3):216-223.
    View in: PubMed
    Score: 0.017
  44. D'Alessandro A, Thomas T, Dzieciatkowska M, Hill RC, Francis RO, Hudson KE, Zimring JC, Hod EA, Spitalnik SL, Hansen KC. Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level. J Proteome Res. 2020 11 06; 19(11):4417-4427.
    View in: PubMed
    Score: 0.017
  45. Thomas T, Stefanoni D, Reisz JA, Nemkov T, Bertolone L, Francis RO, Hudson KE, Zimring JC, Hansen KC, Hod EA, Spitalnik SL, D'Alessandro A. COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight. 2020 07 23; 5(14).
    View in: PubMed
    Score: 0.017
  46. D'Alessandro A, Fu X, Reisz JA, Kanias T, Page GP, Stone M, Kleinman S, Zimring JC, Busch M. Stored RBC metabolism as a function of caffeine levels. Transfusion. 2020 06; 60(6):1197-1211.
    View in: PubMed
    Score: 0.017
  47. D'Alessandro A, Fu X, Reisz JA, Stone M, Kleinman S, Zimring JC, Busch M. Ethyl glucuronide, a marker of alcohol consumption, correlates with metabolic markers of oxidant stress but not with hemolysis in stored red blood cells from healthy blood donors. Transfusion. 2020 06; 60(6):1183-1196.
    View in: PubMed
    Score: 0.017
  48. D'Alessandro A, Xia Y. Erythrocyte adaptive metabolic reprogramming under physiological and pathological hypoxia. Curr Opin Hematol. 2020 05; 27(3):155-162.
    View in: PubMed
    Score: 0.017
  49. Bertolone L, Roy MK, Hay AM, Morrison EJ, Stefanoni D, Fu X, Kanias T, Kleinman S, Dumont LJ, Stone M, Nemkov T, Busch MP, Zimring JC, D'Alessandro A. Impact of taurine on red blood cell metabolism and implications for blood storage. Transfusion. 2020 06; 60(6):1212-1226.
    View in: PubMed
    Score: 0.017
  50. Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A. Decoding the metabolic landscape of pathophysiological stress-induced cell death in anucleate red blood cells. Blood Transfus. 2020 03; 18(2):130-142.
    View in: PubMed
    Score: 0.017
  51. D'Alessandro A, Yoshida T, Nestheide S, Nemkov T, Stocker S, Stefanoni D, Mohmoud F, Rugg N, Dunham A, Cancelas JA. Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery. Transfusion. 2020 04; 60(4):786-798.
    View in: PubMed
    Score: 0.017
  52. D'Alessandro A, Thomas KA, Stefanoni D, Gamboni F, Shea SM, Reisz JA, Spinella PC. Metabolic phenotypes of standard and cold-stored platelets. Transfusion. 2020 06; 60 Suppl 3:S96-S106.
    View in: PubMed
    Score: 0.016
  53. Stefanoni D, Shin HKH, Baek JH, Champagne DP, Nemkov T, Thomas T, Francis RO, Zimring JC, Yoshida T, Reisz JA, Spitalnik SL, Buehler PW, D'Alessandro A. Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage. Haematologica. 2020 08; 105(8):2174-2186.
    View in: PubMed
    Score: 0.016
  54. Moore HB, Culp-Hill R, Reisz JA, Lawson PJ, Sauaia A, Schulick RD, Del Chiaro M, Nydam TL, Moore EE, Hansen KC, D'Alessandro A. The metabolic time line of pancreatic cancer: Opportunities to improve early detection of adenocarcinoma. Am J Surg. 2019 12; 218(6):1206-1212.
    View in: PubMed
    Score: 0.016
  55. Gehrke S, Shah N, Gamboni F, Kamyszek R, Srinivasan AJ, Gray A, Landrigan M, Welsby I, D'Alessandro A. Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients. Transfusion. 2019 10; 59(10):3102-3112.
    View in: PubMed
    Score: 0.016
  56. D'Alessandro A, Liumbruno G. Personalised Transfusion Medicine. Blood Transfus. 2019 07; 17(4):255-257.
    View in: PubMed
    Score: 0.016
  57. D'Alessandro A, Hansen KC, Eisenmesser EZ, Zimring JC. Protect, repair, destroy or sacrifice: a role of oxidative stress biology in inter-donor variability of blood storage? Blood Transfus. 2019 07; 17(4):281-288.
    View in: PubMed
    Score: 0.016
  58. D'Alessandro A, Reisz JA, Zhang Y, Gehrke S, Alexander K, Kanias T, Triulzi DJ, Donadee C, Barge S, Badlam J, Jain S, Risbano MG, Gladwin MT. Effects of aged stored autologous red blood cells on human plasma metabolome. Blood Adv. 2019 03 26; 3(6):884-896.
    View in: PubMed
    Score: 0.016
  59. D'Alessandro A, Zimring JC, Busch M. Chronological storage age and metabolic age of stored red blood cells: are they the same? Transfusion. 2019 05; 59(5):1620-1623.
    View in: PubMed
    Score: 0.015
  60. D'Alessandro A. From omics technologies to personalized transfusion medicine. Expert Rev Proteomics. 2019 03; 16(3):215-225.
    View in: PubMed
    Score: 0.015
  61. Yoshida T, Prudent M, D'alessandro A. Red blood cell storage lesion: causes and potential clinical consequences. Blood Transfus. 2019 01; 17(1):27-52.
    View in: PubMed
    Score: 0.015
  62. D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC. Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics. Transfusion. 2019 01; 59(1):89-100.
    View in: PubMed
    Score: 0.015
  63. Nemkov T, Reisz JA, Xia Y, Zimring JC, D'Alessandro A. Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport. Expert Rev Proteomics. 2018 11; 15(11):855-864.
    View in: PubMed
    Score: 0.015
  64. Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A. Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells. Transfusion. 2018 12; 58(12):2978-2991.
    View in: PubMed
    Score: 0.015
  65. Culp-Hill R, Srinivasan AJ, Gehrke S, Kamyszek R, Ansari A, Shah N, Welsby I, D'Alessandro A. Effects of red blood cell (RBC) transfusion on sickle cell disease recipient plasma and RBC metabolism. Transfusion. 2018 12; 58(12):2797-2806.
    View in: PubMed
    Score: 0.015
  66. Catala A, Culp-Hill R, Nemkov T, D'Alessandro A. Quantitative metabolomics comparison of traditional blood draws and TAP capillary blood collection. Metabolomics. 2018 07 12; 14(7):100.
    View in: PubMed
    Score: 0.015
  67. Gehrke S, Srinivasan AJ, Culp-Hill R, Reisz JA, Ansari A, Gray A, Landrigan M, Welsby I, D'Alessandro A. Metabolomics evaluation of early-storage red blood cell rejuvenation at 4°C and 37°C. Transfusion. 2018 08; 58(8):1980-1991.
    View in: PubMed
    Score: 0.015
  68. D'Alessandro A, Reisz JA, Culp-Hill R, Korsten H, van Bruggen R, de Korte D. Metabolic effect of alkaline additives and guanosine/gluconate in storage solutions for red blood cells. Transfusion. 2018 08; 58(8):1992-2002.
    View in: PubMed
    Score: 0.015
  69. Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A. When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. Expert Rev Proteomics. 2018 04; 15(4):293-309.
    View in: PubMed
    Score: 0.014
  70. Reisz JA, Wither MJ, Moore EE, Slaughter AL, Moore HB, Ghasabyan A, Chandler J, Schaub LJ, Fragoso M, Nunns G, Silliman CC, Hansen KC, Banerjee A, Sheppard FR, D'Alessandro A. All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients. J Trauma Acute Care Surg. 2018 03; 84(3):537-541.
    View in: PubMed
    Score: 0.014
  71. Clendenen N, D'Alessandro A. High Throughput Metabolomics in Clinical Studies: Review and New Applications to Remote Ischemic Preconditioning. Curr Top Med Chem. 2018; 18(25):2143-2153.
    View in: PubMed
    Score: 0.014
  72. Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A. Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage. Haematologica. 2018 02; 103(2):361-372.
    View in: PubMed
    Score: 0.014
  73. D'Alessandro A, Nozik-Grayck E, Stenmark KR. Identification of Infants at Risk for Chronic Lung Disease at Birth. Potential for a Personalized Approach to Disease Prevention. Am J Respir Crit Care Med. 2017 10 15; 196(8):951-952.
    View in: PubMed
    Score: 0.014
  74. Gehrke S, Reisz JA, Nemkov T, Hansen KC, D'Alessandro A. Characterization of rapid extraction protocols for high-throughput metabolomics. Rapid Commun Mass Spectrom. 2017 Sep 15; 31(17):1445-1452.
    View in: PubMed
    Score: 0.014
  75. D'Alessandro A, Moore HB, Moore EE, Reisz JA, Wither MJ, Ghasasbyan A, Chandler J, Silliman CC, Hansen KC, Banerjee A. Plasma succinate is a predictor of mortality in critically injured patients. J Trauma Acute Care Surg. 2017 09; 83(3):491-495.
    View in: PubMed
    Score: 0.014
  76. Reisz JA, D'Alessandro A. Measurement of metabolic fluxes using stable isotope tracers in whole animals and human patients. Curr Opin Clin Nutr Metab Care. 2017 Sep; 20(5):366-374.
    View in: PubMed
    Score: 0.014
  77. D'Alessandro A, El Kasmi KC, Plecitá-Hlavatá L, Je?ek P, Li M, Zhang H, Gupte SA, Stenmark KR. Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming. Antioxid Redox Signal. 2018 Jan 20; 28(3):230-250.
    View in: PubMed
    Score: 0.014
  78. Nemkov T, Hansen KC, D'Alessandro A. A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways. Rapid Commun Mass Spectrom. 2017 Apr 30; 31(8):663-673.
    View in: PubMed
    Score: 0.014
  79. D'Alessandro A, Gray AD, Szczepiorkowski ZM, Hansen K, Herschel LH, Dumont LJ. Red blood cell metabolic responses to refrigerated storage, rejuvenation, and frozen storage. Transfusion. 2017 04; 57(4):1019-1030.
    View in: PubMed
    Score: 0.013
  80. D'Alessandro A, Seghatchian J. Hitchhiker's guide to the red cell storage galaxy: Omics technologies and the quality issue. Transfus Apher Sci. 2017 Apr; 56(2):248-253.
    View in: PubMed
    Score: 0.013
  81. D'alessandro A, Liumbruno GM. Red blood cell storage and clinical outcomes: new insights. Blood Transfus. 2017 03; 15(2):101-103.
    View in: PubMed
    Score: 0.013
  82. D'alessandro A, Nemkov T, Reisz J, Dzieciatkowska M, Wither MJ, Hansen KC. Omics markers of the red cell storage lesion and metabolic linkage. Blood Transfus. 2017 Mar; 15(2):137-144.
    View in: PubMed
    Score: 0.013
  83. D'Alessandro A, Dzieciatkowska M, Nemkov T, Hansen KC. Red blood cell proteomics update: is there more to discover? Blood Transfus. 2017 03; 15(2):182-187.
    View in: PubMed
    Score: 0.013
  84. D'Alessandro A, Zolla L. Proteomic analysis of red blood cells and the potential for the clinic: what have we learned so far? Expert Rev Proteomics. 2017 03; 14(3):243-252.
    View in: PubMed
    Score: 0.013
  85. D'Alessandro A, Nemkov T, Yoshida T, Bordbar A, Palsson BO, Hansen KC. Citrate metabolism in red blood cells stored in additive solution-3. Transfusion. 2017 02; 57(2):325-336.
    View in: PubMed
    Score: 0.013
  86. D'Alessandro A, Nemkov T, Sun K, Liu H, Song A, Monte AA, Subudhi AW, Lovering AT, Dvorkin D, Julian CG, Kevil CG, Kolluru GK, Shiva S, Gladwin MT, Xia Y, Hansen KC, Roach RC. AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia. J Proteome Res. 2016 10 07; 15(10):3883-3895.
    View in: PubMed
    Score: 0.013
  87. Reisz JA, Wither MJ, Dzieciatkowska M, Nemkov T, Issaian A, Yoshida T, Dunham AJ, Hill RC, Hansen KC, D'Alessandro A. Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. Blood. 2016 09 22; 128(12):e32-42.
    View in: PubMed
    Score: 0.013
  88. D'alessandro A, Nemkov T, Moore HB, Moore EE, Wither M, Nydam T, Slaughter A, Silliman CC, Banerjee A, Hansen KC. Metabolomics of trauma-associated death: shared and fluid-specific features of human plasma vs lymph. Blood Transfus. 2016 05; 14(2):185-94.
    View in: PubMed
    Score: 0.013
  89. D'Alessandro A, Dzieciatkowska M, Hill RC, Hansen KC. Supernatant protein biomarkers of red blood cell storage hemolysis as determined through an absolute quantification proteomics technology. Transfusion. 2016 06; 56(6):1329-39.
    View in: PubMed
    Score: 0.012
  90. D'alessandro A. Leucoreduction of blood components: clinical and molecular evidence. Blood Transfus. 2016 05; 14(2):212-3.
    View in: PubMed
    Score: 0.012
  91. Nemkov T, Hansen KC, Dumont LJ, D'Alessandro A. Metabolomics in transfusion medicine. Transfusion. 2016 Apr; 56(4):980-93.
    View in: PubMed
    Score: 0.012
  92. D'alessandro A, Nemkov T, Hansen KC. Rapid detection of DEHP in packed red blood cells stored under European and US standard conditions. Blood Transfus. 2016 Mar; 14(2):140-4.
    View in: PubMed
    Score: 0.012
  93. D'Alessandro A, Nemkov T, Hansen KC, Szczepiorkowski ZM, Dumont LJ. Red blood cell storage in additive solution-7 preserves energy and redox metabolism: a metabolomics approach. Transfusion. 2015 Dec; 55(12):2955-66.
    View in: PubMed
    Score: 0.012
  94. D'Alessandro A, Nemkov T, Kelher M, West FB, Schwindt RK, Banerjee A, Moore EE, Silliman CC, Hansen KC. Routine storage of red blood cell (RBC) units in additive solution-3: a comprehensive investigation of the RBC metabolome. Transfusion. 2015 Jun; 55(6):1155-68.
    View in: PubMed
    Score: 0.012
  95. D'Alessandro A, Amelio I, Berkers CR, Antonov A, Vousden KH, Melino G, Zolla L. Metabolic effect of TAp63a: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense. Oncotarget. 2014 Sep 15; 5(17):7722-33.
    View in: PubMed
    Score: 0.011
  96. D'Alessandro A, Hansen KC, Silliman CC, Moore EE, Kelher M, Banerjee A. Metabolomics of AS-5 RBC supernatants following routine storage. Vox Sang. 2015 Feb; 108(2):131-40.
    View in: PubMed
    Score: 0.011
  97. D'Alessandro A, Kriebardis AG, Rinalducci S, Antonelou MH, Hansen KC, Papassideri IS, Zolla L. An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies. Transfusion. 2015 Jan; 55(1):205-19.
    View in: PubMed
    Score: 0.011
  98. D'Alessandro A, Zolla L. Proteomics and metabolomics in cancer drug development. Expert Rev Proteomics. 2013 Oct; 10(5):473-88.
    View in: PubMed
    Score: 0.011
  99. D'Alessandro A, Marrocco C, Rinalducci S, Peschiaroli A, Timperio AM, Bongiorno-Borbone L, Finazzi Agrò A, Melino G, Zolla L. Analysis of TAp73-dependent signaling via omics technologies. J Proteome Res. 2013 Sep 06; 12(9):4207-20.
    View in: PubMed
    Score: 0.011
  100. D'Alessandro A, Mirasole C, Zolla L. Haemoglobin glycation (Hb1Ac) increases during red blood cell storage: a MALDI-TOF mass-spectrometry-based investigation. Vox Sang. 2013 Aug; 105(2):177-80.
    View in: PubMed
    Score: 0.010
  101. D'Alessandro A, Gevi F, Zolla L. Red blood cell metabolism under prolonged anaerobic storage. Mol Biosyst. 2013 Jun; 9(6):1196-209.
    View in: PubMed
    Score: 0.010
  102. Zolla L, D'alessandro A. Response to "Platelets proteomics in transfusion medicine: a reality with challenging but promising future". Blood Transfus. 2013 Apr; 11(2):316.
    View in: PubMed
    Score: 0.010
  103. D'Alessandro A, Zolla L. Meat science: From proteomics to integrated omics towards system biology. J Proteomics. 2013 Jan 14; 78:558-77.
    View in: PubMed
    Score: 0.010
  104. Zolla L, D'Alessandro A. Preface to the Special Issue: Integrated omics. J Proteomics. 2012 Dec 05; 76 Spec No.:3-9.
    View in: PubMed
    Score: 0.010
  105. D'Alessandro A, Blasi B, D'Amici GM, Marrocco C, Zolla L. Red blood cell subpopulations in freshly drawn blood: application of proteomics and metabolomics to a decades-long biological issue. Blood Transfus. 2013 Jan; 11(1):75-87.
    View in: PubMed
    Score: 0.010
  106. D'Alessandro A, Giardina B, Gevi F, Timperio AM, Zolla L. Clinical metabolomics: the next stage of clinical biochemistry. Blood Transfus. 2012 May; 10 Suppl 2:s19-24.
    View in: PubMed
    Score: 0.010
  107. D'Alessandro A, Gevi F, Zolla L. Targeted mass spectrometry-based metabolomic profiling through multiple reaction monitoring of liver and other biological matrices. Methods Mol Biol. 2012; 909:279-94.
    View in: PubMed
    Score: 0.009
  108. D'Alessandro A, Federica G, Palini S, Bulletti C, Zolla L. A mass spectrometry-based targeted metabolomics strategy of human blastocoele fluid: a promising tool in fertility research. Mol Biosyst. 2012 Apr; 8(4):953-8.
    View in: PubMed
    Score: 0.009
  109. D'Alessandro A, Zolla L. We are what we eat: food safety and proteomics. J Proteome Res. 2012 Jan 01; 11(1):26-36.
    View in: PubMed
    Score: 0.009
  110. D'Alessandro A, D'Amici GM, Vaglio S, Zolla L. Time-course investigation of SAGM-stored leukocyte-filtered red bood cell concentrates: from metabolism to proteomics. Haematologica. 2012 Jan; 97(1):107-15.
    View in: PubMed
    Score: 0.009
  111. D'Alessandro A, Zolla L. Metabolomics and cancer drug discovery: let the cells do the talking. Drug Discov Today. 2012 Jan; 17(1-2):3-9.
    View in: PubMed
    Score: 0.009
  112. D'Alessandro A, D'Amici GM, Timperio AM, Merendino N, Zolla L. Docosohaexanoic acid-supplemented PACA44 cell lines and over-activation of Krebs cycle: an integrated proteomic, metabolomic and interactomic overview. J Proteomics. 2011 Sep 06; 74(10):2138-58.
    View in: PubMed
    Score: 0.009
  113. D'Alessandro A, Zolla L. The SODyssey: superoxide dismutases from biochemistry, through proteomics, to oxidative stress, aging and nutraceuticals. Expert Rev Proteomics. 2011 Jun; 8(3):405-21.
    View in: PubMed
    Score: 0.009
  114. D'Alessandro A, Gevi F, Zolla L. A robust high resolution reversed-phase HPLC strategy to investigate various metabolic species in different biological models. Mol Biosyst. 2011 Apr; 7(4):1024-32.
    View in: PubMed
    Score: 0.009
  115. D'Alessandro A, Rinalducci S, Zolla L. Redox proteomics and drug development. J Proteomics. 2011 Nov 18; 74(12):2575-95.
    View in: PubMed
    Score: 0.009
  116. D'Alessandro A, Zolla L. Pharmacoproteomics: a chess game on a protein field. Drug Discov Today. 2010 Dec; 15(23-24):1015-23.
    View in: PubMed
    Score: 0.009
  117. D'Alessandro A, Zolla L, Scaloni A. The bovine milk proteome: cherishing, nourishing and fostering molecular complexity. An interactomics and functional overview. Mol Biosyst. 2011 Mar; 7(3):579-97.
    View in: PubMed
    Score: 0.009
  118. D'Alessandro A, Scaloni A, Zolla L. Human milk proteins: an interactomics and updated functional overview. J Proteome Res. 2010 Jul 02; 9(7):3339-73.
    View in: PubMed
    Score: 0.008
  119. D'Alessandro A, Zolla L. Proteomics for quality-control processes in transfusion medicine. Anal Bioanal Chem. 2010 Sep; 398(1):111-24.
    View in: PubMed
    Score: 0.008
  120. D'Alessandro A, Liumbruno G, Grazzini G, Zolla L. Red blood cell storage: the story so far. Blood Transfus. 2010 Apr; 8(2):82-8.
    View in: PubMed
    Score: 0.008
  121. D'Alessandro A, Righetti PG, Zolla L. The red blood cell proteome and interactome: an update. J Proteome Res. 2010 Jan; 9(1):144-63.
    View in: PubMed
    Score: 0.008
  122. Bellingham JM, Anderson ME, D'Alessandro AM. Successful kidney transplantation from a donation after cardiac death donor with an ileal conduit. Transplant Proc. 2009 Dec; 41(10):4420-1.
    View in: PubMed
    Score: 0.008
  123. D'Alessandro A, Liumbruno G, Grazzini G, Pupella S, Lombardini L, Zolla L. Umbilical cord blood stem cells: towards a proteomic approach. J Proteomics. 2010 Jan 03; 73(3):468-82.
    View in: PubMed
    Score: 0.008
  124. O'Brien C, Nursimulu N, Tyagi A, Culp-Hill R, Arruda A, Murphy T, Minden MD, Kent A, Stevens B, Pollyea DA, Hope K, Kumar S, Reisz JA, D'Alessandro A, Jones CL. Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia. Blood. 2025 Nov 20; 146(21):2589-2596.
    View in: PubMed
    Score: 0.006
  125. van Wonderen SF, van Baarle FLF, Phelp PG, Bulle EB, Argabright A, de Bruin S, Tuip-de Boer AM, Polet CA, van Amstel RBE, Lim EHT, Schenk J, Peters AL, van Bruggen R, Reisz JA, Vermeulen C, Klei TRL, Biemond BJ, Müller MCA, D'Alessandro A, Vlaar APJ. Posttransfusion recovery, quality, and metabolism of short- and long-term stored platelets during controlled inflammation. Blood Adv. 2025 Oct 28; 9(20):5164-5176.
    View in: PubMed
    Score: 0.006
  126. Snoke DB, van der Velden JL, Bellafleur ER, Dearborn JS, Lenahan SM, Beal AE, Aboushousha R, Heininger SCJ, Ather JL, Mank MM, Sarausky H, Stephenson D, Reisz JA, D'Alessandro A, Majumdar D, Ahern TP, Xu K, Sandler KL, Landman BA, Janssen-Heininger YMW, Poynter ME, Seward DJ, Toth MJ. Early adipose tissue wasting in a preclinical model of human lung cancer cachexia. Cell Rep. 2025 Sep 23; 44(9):116278.
    View in: PubMed
    Score: 0.006
  127. Oshima K, Di Gravio C, Yan B, McMurtry SA, Burke R, Levoir LM, Kravitz MS, Stephenson D, Issaian A, Hansen KC, D'Alessandro A, Douglas IS, Self WH, Lindsell CJ, Schildcrout JS, Schmidt EP, Shapiro NI. Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial. Ann Am Thorac Soc. 2025 Sep; 22(9):1382-1393.
    View in: PubMed
    Score: 0.006
  128. Wölnerhanssen BK, Meyer-Gerspach AC, Arduini A, D'Alessandro A, Gronda E, Carugo S, Bonomini M, Gallieni M, Masola V, Angelillo-Scherrer A, Prosdocimi T, Lopaschuk GD. Sweeteners: erythritol, xylitol and cardiovascular risk-friend or foe? Cardiovasc Res. 2025 Aug 14; 121(9):1319-1329.
    View in: PubMed
    Score: 0.006
  129. Chatzinikolaou PN, Margaritelis NV, Paschalis V, Theodorou AA, Moushi E, Vrabas IS, Kyparos A, Fatouros IG, D'Alessandro A, Nikolaidis MG. Erythrocyte Glycolytic and Redox Metabolism Affects Muscle Oxygenation and Exercise Performance: A Randomized Double-Blind Crossover Study in Men. Sports Med. 2025 Dec; 55(12):3157-3181.
    View in: PubMed
    Score: 0.006
  130. Skuli SJ, Bakayoko A, Kruidenier M, Manning B, Pammer P, Salimov A, Riley O, Brake-Sillá G, Dopkin D, Bowman M, Martinez-Gutierrez LN, Anderson CC, Reisz JA, Buono R, Paul M, Saland E, Liccardo F, DeVine A, Wong S, Xu JP, Nee E, Hausler R, Boettcher S, Sebti SM, Lai C, Maxwell KN, Sarry JE, Fruman DA, D'Alessandro A, Mesaros C, Keith B, Simon MC, Sung PJ, Wertheim G, Skuli N, Bowman RL, Matthews A, Carroll M. Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response. Leukemia. 2025 Sep; 39(9):2087-2098.
    View in: PubMed
    Score: 0.006
  131. Schaid TR, Erickson C, D'Alessandro A, Hansen K, Thielen O, Hallas W, Gallagher L, Cralley A, LaCroix I, Ramser B, Stocker B, Mitra S, Stafford P, Dzieciatkowska M, Silliman C, Cohen M. Obesity influences the biological response to injury: a multi-omics analysis. Eur J Trauma Emerg Surg. 2025 Jun 27; 51(1):238.
    View in: PubMed
    Score: 0.006
  132. Siciliano A, D'Alessandro A, Matte A, Bisello G, Bertoldi M, Dzieciatkowska M, Argabright A, Pozzetto RH, Riccardi V, Mattarei A, Ongaro A, Ceolan J, Russo R, Rivadeneyra L, Wind-Rotolo M, Iolascon A, Brugnara C, De Franceschi L. Mitapivat metabolically reprograms human ß-thalassemic erythroblasts, increasing their responsiveness to oxidation. Blood Adv. 2025 Jun 10; 9(11):2818-2830.
    View in: PubMed
    Score: 0.006
  133. Deng X, Di Germanio C, Marques de Menezes EG, Milani P, Stone M, Tanner H, Bakkour SC, Chafets DM, Reese SE, Roubinian NH, Kleinman S, Kanias T, Busch MP, Earley EJ, Page GP, Nemkov T, D'Alessandro A, Norris PJ. Donor genetics and storage conditions influence mitochondrial DNA and extracellular vesicle levels in RBC units. JCI Insight. 2025 Jul 22; 10(14).
    View in: PubMed
    Score: 0.006
  134. Rojas-Sanchez G, Calzada-Martinez J, McMahon B, Petrey AC, Dveksler G, Espino-Solis GP, Esparza O, Hernandez G, Le D, Wartchow EP, Jones K, Ting LH, Jankowski C, Kelher MR, Manco-Johnson M, Feser ML, Deane KD, Nemkov T, D'Alessandro A, Thorburn A, Maycotte P, López JA, Davizon-Castillo P. TNF-a impairs platelet function by inhibiting autophagy and disrupting metabolism via syntaxin 17 downregulation. J Clin Invest. 2025 Aug 01; 135(15).
    View in: PubMed
    Score: 0.006
  135. Lee MH, Menezes TCF, Reisz JA, Cendali FI, Ferreira EVM, Ota-Arakaki JS, Sperandio PA, Kumar R, Mickael C, Ieong MM, Santos JL, Duarte ACB, Fonseca Balladares DC, Nolan K, Tuder RM, Hassoun PM, D'Alessandro A, Oliveira RKF, Graham BB. Physiologic relevance of the transpulmonary metabolome in connective tissue disease-associated pulmonary vascular disease. JCI Insight. 2025 May 08; 10(9).
    View in: PubMed
    Score: 0.006
  136. Riccardi V, Viscomi CF, Sandri M, D'Alessandro A, Dzieciatkowska M, Stephenson D, Federti E, Hermann A, Salviati L, Siciliano A, Andolfo I, Alper SL, Ceolan J, Iolascon A, Vattemi G, Danek A, Walker RH, Mensch A, Otto M, Deschauer M, Armbrust M, Beninca' C, Salari V, Fabene P, Peikert K, De Franceschi L. Premature skeletal muscle aging in VPS13A deficiency relates to impaired autophagy. Acta Neuropathol Commun. 2025 04 24; 13(1):83.
    View in: PubMed
    Score: 0.006
  137. Tajpara P, Sobkowiak MJ, Healy K, Naud S, Gündel B, Halimi A, Khan ZA, Gabarrini G, Le Guyader S, Imreh G, Reisz JA, Del Chiaro M, D'Alessandro A, Heuchel R, Löhr JM, Özenci V, Sällberg Chen M. Patient-derived pancreatic tumor bacteria exhibit oncogenic properties and are recognized by MAIT cells in tumor spheroids. Front Immunol. 2025; 16:1553034.
    View in: PubMed
    Score: 0.006
  138. Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Egan G, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs. Nature. 2025 Jun; 642(8067):421-430.
    View in: PubMed
    Score: 0.006
  139. Cotton K, Comer C, Caporali S, Butera A, Gurres S, Capradossi F, D'Alessandro A, Amelio I, Niklison-Chirou MV. Lipidome atlas of p53 mutant variants in pancreatic cancer. Biol Direct. 2025 Apr 11; 20(1):51.
    View in: PubMed
    Score: 0.006
  140. Molteni R, Fiumara M, Campochiaro C, Alfieri R, Pacini G, Licari E, Tomelleri A, Diral E, Varesi A, Weber A, Quaranta P, Albano L, Gaddoni C, Basso-Ricci L, Stefanoni D, Alessandrini L, Degl'Innocenti S, Sanvito F, Bergonzi GM, Annoni A, Panigada M, Cantoni E, Canarutto D, Xie SZ, D'Alessandro A, Di Micco R, Aiuti A, Ciceri F, De Luca G, Dagna L, Matucci-Cerinic M, Merelli I, Cenci S, Scala S, Cavalli G, Naldini L, Ferrari S. Mechanisms of hematopoietic clonal dominance in VEXAS syndrome. Nat Med. 2025 Jun; 31(6):1911-1924.
    View in: PubMed
    Score: 0.006
  141. Haiman ZB, Key A, D'Alessandro A, Palsson BO. RBC-GEM: A genome-scale metabolic model for systems biology of the human red blood cell. PLoS Comput Biol. 2025 Mar; 21(3):e1012109.
    View in: PubMed
    Score: 0.006
  142. Peltier S, Marin M, Dzieciatkowska M, Dussiot M, Roy MK, Bruce J, Leblanc L, Hadjou Y, Georgeault S, Fricot A, Roussel C, Stephenson D, Casimir M, Sissoko A, Paye F, Dokmak S, Ndour PA, Roingeard P, Gautier EF, Spitalnik SL, Hermine O, Buffet PA, D'Alessandro A, Amireault P. Proteostasis and metabolic dysfunction characterize a subset of storage-induced senescent erythrocytes targeted for posttransfusion clearance. J Clin Invest. 2025 May 01; 135(9).
    View in: PubMed
    Score: 0.006
  143. Trujillo MN, Jennings EQ, Farrera DO, Kitamura N, Anderson CC, Gehrke S, Reisz JA, Johannsen M, Roede JR, D'Alessandro A, Galligan JJ. Glyoxalase 2 Coordinates de Novo Serine Metabolism. Chembiochem. 2025 Apr 01; 26(7):e202401086.
    View in: PubMed
    Score: 0.006
  144. Bischoff ME, Shamsaei B, Yang J, Secic D, Vemuri B, Reisz JA, D'Alessandro A, Bartolacci C, Adamczak R, Schmidt L, Wang J, Martines A, Venkat J, Tcheuyap VT, Biesiada J, Behrmann CA, Vest KE, Brugarolas J, Scaglioni PP, Plas DR, Patra KC, Gulati S, Landero Figueroa JA, Meller J, Cunningham JT, Czyzyk-Krzeska MF. Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma. Cancer Discov. 2025 Feb 07; 15(2):401-426.
    View in: PubMed
    Score: 0.006
  145. Darvish S, Murray KO, Ludwig KR, Avalani KH, Craighead DH, Freeberg KA, Bevers S, Reisz JA, D'Alessandro A, Moreau KL, Seals DR, Rossman MJ. Preservation of Vascular Endothelial Function in Late-Onset Postmenopausal Women. Circ Res. 2025 Feb 28; 136(5):455-469.
    View in: PubMed
    Score: 0.006
  146. Lucero MJ, Lisk C, Cendali F, Swindle D, Setua S, Thangaraju K, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Rana N, Khan S, Westover N, DavizonCastillo P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Palmer AF, D'Alessandro A, Buehler PW, Irwin DC. Targeting lung heme iron by aerosol hemopexin adminstration in sickle cell disease pulmonary hypertension. Free Radic Biol Med. 2025 Mar 01; 229:458-473.
    View in: PubMed
    Score: 0.006
  147. Goleva E, Berdyshev E, Kreimer S, Reisz JA, D'Alessandro A, Bronova I, Lyubchenko T, Richers BN, Hall CF, Xiao O, Bronoff AS, Bafna S, Agueusop I, Gloaguen E, Zahn J, Bissonnette R, Zhang A, Leung DYM. Longitudinal integrated proteomic and metabolomic skin changes in patients with atopic dermatitis treated with dupilumab. J Allergy Clin Immunol. 2025 May; 155(5):1536-1546.
    View in: PubMed
    Score: 0.006
  148. Minhajuddin M, Winters A, Ye H, Pei S, Stevens B, Gillen A, Engel K, Gipson S, Ransom M, Amaya M, Inguva A, Gasparetto M, Althoff MJ, Miller R, Shelton I, Tolison H, Krug A, Culp-Hill R, D'Alessandro A, Sherbenou DW, Pollyea DA, Smith C, Jordan CT. Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia. Haematologica. 2025 Jan 01; 110(1):103-116.
    View in: PubMed
    Score: 0.006
  149. Lee E, Saviola A, Bevers S, Redzic JS, Maroney SP, Shaw S, Tamkin E, Fulte S, Nemkov T, Meyer N, D'Alessandro A, Hansen KC, Clark SE, Eisenmesser E. Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection. Protein Sci. 2025 Jan; 34(1):e5253.
    View in: PubMed
    Score: 0.006
  150. Iacono G, Abay A, Murillo JSG, Aglialoro F, Yagci N, Varga E, Bijlsma T, Sohler J, Fu K, Reisz JA, Argabright A, D'Alessandro A, Svendsen AF, von Lindern M, van den Akker E. Differentiating erythroblasts adapt to mechanical stimulation by upregulation of cholesterol biosynthesis via S1P/SREBP-induced HMGCR expression. Sci Rep. 2024 12 04; 14(1):30157.
    View in: PubMed
    Score: 0.006
  151. Caporali S, Butera A, Ruzza A, Zampieri C, Bantula' M, Scharsich S, Ückert AK, Celardo I, Kouzel IU, Leanza L, Gruber A, Montero J, D'Alessandro A, Brunner T, Leist M, Amelio I. Selective metabolic regulations by p53 mutant variants in pancreatic cancer. J Exp Clin Cancer Res. 2024 Nov 26; 43(1):310.
    View in: PubMed
    Score: 0.006
  152. Dumont LJ, Kelly K, Nemkov T, Leite C, Gresens CJ, Stanley C, D'Alessandro A, Vassallo RR. Platelet storage failure-Metformin as causative agent. Transfusion. 2024 12; 64(12):2405-2409.
    View in: PubMed
    Score: 0.006
  153. Darrah MA, Longtine AG, Greenberg NT, Mahoney SA, Venkatasubramanian R, VanDongen NS, Reisz JA, D'Alessandro A, Seals DR, de Quiros Miranda YB, Clayton ZS. The influence of a human macronutrient-matched diet on phenotypes in old mice. Geroscience. 2025 Apr; 47(2):2293-2308.
    View in: PubMed
    Score: 0.006
  154. Scuoppo C, Cai B, Ofori K, Scholze H, Kumar R, D'Alessandro A, Basso K, Pasqualucci L, Dalla-Favera R. Repurposing NAMPT Inhibitors for Germinal Center B Cell-Like Diffuse Large B-Cell Lymphoma. Blood Cancer Discov. 2024 Nov 01; 5(6):417-427.
    View in: PubMed
    Score: 0.006
  155. Ionescu RB, Nicaise AM, Reisz JA, Williams EC, Prasad P, Willis CM, Simões-Abade MBC, Sbarro L, Dzieciatkowska M, Stephenson D, Suarez Cubero M, Rizzi S, Pirvan L, Peruzzotti-Jametti L, Fossati V, Edenhofer F, Leonardi T, Frezza C, Mohorianu I, D'Alessandro A, Pluchino S. Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis. Cell Stem Cell. 2024 Nov 07; 31(11):1574-1590.e11.
    View in: PubMed
    Score: 0.006
  156. Martins Freire C, King NR, Dzieciatkowska M, Stephenson D, Moura PL, Dobbe JGG, Streekstra GJ, D'Alessandro A, Toye AM, Satchwell TJ. Complete absence of GLUT1 does not impair human terminal erythroid differentiation. Blood Adv. 2024 10 08; 8(19):5166-5178.
    View in: PubMed
    Score: 0.006
  157. Lee SCS, Pyo AHA, Mohammadi H, Zhang J, Dvorkin-Gheva A, Malbeteau L, Chung S, Khan S, Ciudad MT, Rondeau V, Cairns RA, Kislinger T, McGaha TL, Wouters BG, Reisz JA, Culp-Hill R, D'Alessandro A, Jones CL, Koritzinsky M. Cysteamine dioxygenase (ADO) governs cancer cell mitochondrial redox homeostasis through proline metabolism. Sci Adv. 2024 Oct 04; 10(40):eadq0355.
    View in: PubMed
    Score: 0.006
  158. Kuo LW, Crump LS, O'Neill K, Williams MM, Christenson JL, Spoelstra NS, Roy MK, Argabright A, Reisz JA, D'Alessandro A, Boorgula MP, Goodspeed A, Bickerdike M, Bitler BG, Richer JK. Blocking Tryptophan Catabolism Reduces Triple-Negative Breast Cancer Invasive Capacity. Cancer Res Commun. 2024 10 01; 4(10):2699-2713.
    View in: PubMed
    Score: 0.006
  159. Rondeau V, Berman JM, Ling T, O'Brien C, Culp-Hill R, Reisz JA, Wunderlich M, Chueh Y, Jiménez-Camacho KE, Sexton C, Carter KM, Stillwell C, St-Germain J, Yendi D, Gupta A, Shi M, Bourdine A, Paralkar VR, Jahangiri S, Hope KJ, Tikhonova AN, Arruda A, Minden MD, Raught B, D'Alessandro A, Jones CL. Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models. Sci Transl Med. 2024 09 25; 16(766):eadn1285.
    View in: PubMed
    Score: 0.006
  160. Dziewulska-Cronk KH, Reisz JA, Hay AM, Nemkov T, Cendali FI, Issaian A, Lamb DR, Palha MS, Legenzov EA, Kao JPY, Walker LA, Tekwani BL, Buehler PW, D'Alessandro A, Zimring JC. Primaquine-5,6-Orthoquinone Is Directly Hemolytic to Older G6PD Deficient RBCs in a Humanized Mouse Model. J Pharmacol Exp Ther. 2024 09 18; 391(1):119-129.
    View in: PubMed
    Score: 0.006
  161. Earley EJ, D'Alessandro A, Kaestner L, Page GP. Reply to McGowan et al.: An intronic polymorphism associated with 2,3-bisphosphoglycerate levels in human red blood cells is linked to expression of RhCE blood groups. Proc Natl Acad Sci U S A. 2024 Sep 03; 121(36):e2413726121.
    View in: PubMed
    Score: 0.006
  162. Moore LG, Lorca RA, Gumina DL, Wesolowski SR, Reisz JA, Cioffi-Ragan D, Houck JA, Banerji S, Euser AG, D'Alessandro A, Hobbins JC, Julian CG. Maternal AMPK pathway activation with uterine artery blood flow and fetal growth maintenance during hypoxia. Am J Physiol Heart Circ Physiol. 2024 Oct 01; 327(4):H778-H792.
    View in: PubMed
    Score: 0.006
  163. Oatman N, Gawali MV, Congrove S, Cáceres R, Sukumaran A, Gupta N, Murugesan N, Arora P, Subramanian S, Choi K, Abdel-Malek Z, Reisz JA, Stephenson D, Amaravadi R, Desai P, D'Alessandro A, Komurov K, Dasgupta B. A Multimodal Drug-Diet-Immunotherapy Combination Restrains Melanoma Progression and Metastasis. Cancer Res. 2024 Jul 15; 84(14):2333-2351.
    View in: PubMed
    Score: 0.006
  164. Nanaware PP, Khan ZN, Clement CC, Shetty M, Mota I, Seltzer ES, Dzieciatkowska M, Gamboni F, D'Alessandro A, Ng C, Nagayama M, Lichti CF, Soni RK, Matei I, Lyden D, Longman R, Lu TT, Wan X, Unanue ER, Stern LJ, Santambrogio L. Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load. Cell Rep. 2024 06 25; 43(6):114311.
    View in: PubMed
    Score: 0.006
  165. Thielen O, Stafford P, Debot M, Kelher M, Mitra S, Hallas W, Gallagher LT, Schaid T, Stocker B, Ramser B, D'Alessandro A, Hansen K, Silliman CC, Moore E, Mosnier L, Griffin J, Cohen M. Cytoprotective 3K3A-activated protein C and plasma: A comparison of therapeutics for the endotheliopathy of trauma. J Trauma Acute Care Surg. 2025 Jan 01; 98(1):94-100.
    View in: PubMed
    Score: 0.006
  166. Wu MH, Valenca-Pereira F, Cendali F, Giddings EL, Pham-Danis C, Yarnell MC, Novak AJ, Brunetti TM, Thompson SB, Henao-Mejia J, Flavell RA, D'Alessandro A, Kohler ME, Rincon M. Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies. Nat Commun. 2024 May 24; 15(1):4444.
    View in: PubMed
    Score: 0.006
  167. Gallagher LT, LaCroix I, Fields AT, Mitra S, Argabright A, D'Alessandro A, Erickson C, Nunez-Garcia B, Herrera-Rodriguez K, Chou YC, Stocker BW, Ramser BJ, Thielen O, Hallas W, Silliman CC, Kornblith LZ, Cohen MJ. Platelet releasates mitigate the endotheliopathy of trauma. J Trauma Acute Care Surg. 2024 Nov 01; 97(5):738-746.
    View in: PubMed
    Score: 0.006
  168. Stocker BW, LaCroix IS, Erickson C, Gallagher LT, Ramser BJ, Thielen O, Hallas W, Mitra S, Moore EE, Hansen K, D'Alessandro A, Silliman CC, Cohen MJ. Trauma patients with type O blood exhibit unique multiomics signature with decreased lectin pathway of complement levels. J Trauma Acute Care Surg. 2024 Nov 01; 97(5):753-763.
    View in: PubMed
    Score: 0.006
  169. Anastasiadi AT, Arvaniti VZ, Hudson KE, Kriebardis AG, Stathopoulos C, D'Alessandro A, Spitalnik SL, Tzounakas VL. Exploring unconventional attributes of red blood cells and their potential applications in biomedicine. Protein Cell. 2024 May 07; 15(5):315-330.
    View in: PubMed
    Score: 0.006
  170. Ye Q, Jo J, Wang CY, Oh H, Zhan J, Choy TJ, Kim KI, D'Alessandro A, Reshetnyak YK, Jung SY, Chen Z, Marrelli SP, Lee HK. Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation. Cell Rep. 2024 05 28; 43(5):114193.
    View in: PubMed
    Score: 0.006
  171. Ross RB, Gadwa J, Yu J, Darragh LB, Knitz MW, Nguyen D, Olimpo NA, Abdelazeem KNM, Nguyen A, Corbo S, Van Court B, Beynor J, Neupert B, Saviola AJ, D'Alessandro A, Karam SD. PPARa Agonism Enhances Immune Response to Radiotherapy While Dietary Oleic Acid Results in Counteraction. Clin Cancer Res. 2024 May 01; 30(9):1916-1933.
    View in: PubMed
    Score: 0.006
  172. Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression. EMBO Mol Med. 2024 Jun; 16(6):1379-1403.
    View in: PubMed
    Score: 0.006
  173. Guerrelli D, Desai M, Semaan Y, Essa Y, Zurakowski D, Cendali F, Reisz J, D'Alessandro A, Luban N, Posnack NG. Prevalence and clinical implications of heightened plastic chemical exposure in pediatric patients undergoing cardiopulmonary bypass. Transfusion. 2024 05; 64(5):808-823.
    View in: PubMed
    Score: 0.005
  174. Yu J, Gadwa J, Ross RB, Knitz M, Darragh LB, Abdelazeem KNM, Beynor J, Neupert B, Nguyen A, Nguyen D, Olimpo N, Corbo S, Van Court B, D'Alessandro A, Saviola A, Karam SD. IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models. Cancer Immunol Immunother. 2024 Mar 30; 73(5):90.
    View in: PubMed
    Score: 0.005
  175. Gallagher LT, Erickson C, D'Alessandro A, Schaid T, Thielen O, Hallas W, Mitra S, Stafford P, Moore EE, Silliman CC, Calfee CS, Cohen MJ. Smoking primes the metabolomic response in trauma. J Trauma Acute Care Surg. 2024 Jul 01; 97(1):48-56.
    View in: PubMed
    Score: 0.005
  176. Correnti S, Preianò M, Gamboni F, Stephenson D, Pelaia C, Pelaia G, Savino R, D'Alessandro A, Terracciano R. An integrated metabo-lipidomics profile of induced sputum for the identification of novel biomarkers in the differential diagnosis of asthma and COPD. J Transl Med. 2024 03 23; 22(1):301.
    View in: PubMed
    Score: 0.005
  177. Wang L, Rochon ER, Gingras S, Zuchelkowski BE, Sinchar DJ, Alipour E, Reisz JA, Yang M, Page GP, Kanias T, Triulzi DJ, Lee JS, Kim-Shapiro DB, D'Alessandro A, Gladwin MT. Functional effects of an African glucose-6-phosphate dehydrogenase (G6PD) polymorphism (Val68Met) on red blood cell hemolytic propensity and post-transfusion recovery. Transfusion. 2024 04; 64(4):615-626.
    View in: PubMed
    Score: 0.005
  178. He F, Laranjeira AB, Kong T, Lin S, Ashworth KJ, Liu A, Lasky NM, Fisher DA, Cox MJ, Fulbright MC, Antunes-Heck L, Yu L, Brakhane M, Gao B, Sykes SM, D'Alessandro A, Di Paola J, Oh ST. Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms. J Clin Invest. 2024 Feb 01; 134(3).
    View in: PubMed
    Score: 0.005
  179. Hunter SK, Hoffman MC, D'Alessandro A, Freedman R. Developmental Windows for Effects of Choline and Folate on Excitatory and Inhibitory Neurotransmission During Human Gestation. Dev Psychobiol. 2024 02; 66(2).
    View in: PubMed
    Score: 0.005
  180. Heidarian Y, Tourigny JP, Fasteen TD, Mahmoudzadeh NH, Hurlburt AJ, Nemkov T, Reisz JA, D'Alessandro A, Tennessen JM. Metabolomic analysis of Drosophila melanogaster larvae lacking pyruvate kinase. G3 (Bethesda). 2023 12 29; 14(1).
    View in: PubMed
    Score: 0.005
  181. Swift LM, Roberts A, Pressman J, Guerrelli D, Allen S, Haq KT, Reisz JA, D'Alessandro A, Posnack NG. Evidence for the cardiodepressive effects of the plasticizer di-2-ethylhexyl phthalate. Toxicol Sci. 2023 12 21; 197(1):79-94.
    View in: PubMed
    Score: 0.005
  182. Schaid TR, Mitra S, Stafford P, DeBot M, Thielen O, Hallas W, Cralley A, Gallagher L, Jeffrey D, Hansen KC, D'Alessandro A, Silliman CC, Dabertrand F, Cohen MJ. Endothelial Cell Calcium Influx Mediates Trauma-induced Endothelial Permeability. Ann Surg. 2025 Apr 01; 281(4):671-681.
    View in: PubMed
    Score: 0.005
  183. Shea SM, Reisz JA, Mihalko EP, Rahn KC, Rassam RMG, Chitrakar A, Gamboni F, D'Alessandro A, Spinella PC, Thomas KA. Cold-stored platelet hemostatic capacity is maintained for three weeks of storage and associated with taurine metabolism. J Thromb Haemost. 2024 Apr; 22(4):1154-1166.
    View in: PubMed
    Score: 0.005
  184. Cui J, Christin JR, Reisz JA, Cendali FI, Sanawar R, Coutinho De Miranda M, D'Alessandro A, Guo W. Targeting ABCA12-controlled ceramide homeostasis inhibits breast cancer stem cell function and chemoresistance. Sci Adv. 2023 12; 9(48):eadh1891.
    View in: PubMed
    Score: 0.005
  185. Leone MA, Gelati M, Profico DC, Gobbi C, Pravatà E, Copetti M, Conti C, Abate L, Amoruso L, Apollo F, Balzano RF, Bicchi I, Carella M, Ciampini A, Colosimo C, Crociani P, D'Aloisio G, Di Viesti P, Ferrari D, Fogli D, Fontana A, Frondizi D, Grespi V, Kuhle J, Laborante A, Lombardi I, Muzi G, Paci F, Placentino G, Popolizio T, Ricciolini C, Sabatini S, Silveri G, Spera C, Stephenson D, Stipa G, Tinella E, Zarrelli M, Zecca C, Ventura Y, D'Alessandro A, Peruzzotti-Jametti L, Pluchino S, Vescovi AL. Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis. Cell Stem Cell. 2023 12 07; 30(12):1597-1609.e8.
    View in: PubMed
    Score: 0.005
  186. Kim CY, Larsen HJ, Spitalnik SL, Hod EA, Francis RO, Hudson KE, Gordy DE, Stone EF, Peltier S, Amireault P, D'Alessandro A, Zimring JC, Buehler PW, Fu X, Thomas T. Low-Dose Dietary Fish Oil Improves RBC Deformability without Improving Post-Transfusion Recovery in Mice. Nutrients. 2023 Oct 20; 15(20).
    View in: PubMed
    Score: 0.005
  187. Cantoni E, Merelli I, Stefanoni D, Tomelleri A, Campochiaro C, Giordano V, Panigada M, Baldissera EM, Merlo Pich L, Natoli V, Ziogas A, Domínguez-Andrés J, De Luca G, Mazza D, Zambrano S, Gnani D, Ferrarini M, Ferrero E, Agresti A, Vergani B, Leone BE, Cenci S, Ravelli A, Matucci-Cerinic M, D'Alessandro A, Joosten LAB, Dagna L, Netea MG, Molteni R, Cavalli G. Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production. Rheumatology (Oxford). 2023 10 03; 62(10):3469-3479.
    View in: PubMed
    Score: 0.005
  188. Thomas TA, Qiu A, Kim CY, Gordy DE, Miller A, Tredicine M, Dzieciatkowska M, Dei Zotti F, Hod EA, D'Alessandro A, Zimring JC, Spitalnik SL, Hudson KE. Reticulocytes in donor blood units enhance red blood cell alloimmunization. Haematologica. 2023 10 01; 108(10):2639-2651.
    View in: PubMed
    Score: 0.005
  189. Thielen O, Mitra S, Debot M, Schaid T, Hallas W, Gallagher LT, Erickson C, Cralley A, Stafford P, Silliman C, D'Alessandro A, Hansen K, Sauaia A, Moore E, Mosnier L, Griffin J, Cohen M. Mitigation of trauma-induced endotheliopathy by activated protein C: A potential therapeutic for postinjury thromboinflammation. J Trauma Acute Care Surg. 2024 01 01; 96(1):116-122.
    View in: PubMed
    Score: 0.005
  190. Craighead DH, Freeberg KA, Heinbockel TC, Rossman MJ, Jackman RA, McCarty NP, Jankowski LR, Nemkov T, Reisz JA, D'Alessandro A, Chonchol M, Bailey EF, Seals DR. Time-Efficient, High-Resistance Inspiratory Muscle Strength Training Increases Exercise Tolerance in Midlife and Older Adults. Med Sci Sports Exerc. 2024 Feb 01; 56(2):266-276.
    View in: PubMed
    Score: 0.005
  191. O'Brien C, Ling T, Berman JM, Culp-Hill R, Reisz JA, Rondeau V, Jahangiri S, St-Germain J, Macwan V, Astori A, Zeng A, Hong JY, Li M, Yang M, Jana S, Gamboni F, Tsao E, Liu W, Dick JE, Lin H, Melnick A, Tikhonova A, Arruda A, Minden MD, Raught B, D'Alessandro A, Jones CL. Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid ß-oxidation and inducing lipotoxicity. Haematologica. 2023 09 01; 108(9):2343-2357.
    View in: PubMed
    Score: 0.005
  192. Lisk C, Cendali F, Setua S, Thangaraju K, Pak DI, Swindle D, Dzieciatkowska M, Gamboni F, Hassell K, Nuss R, George G, Davizon-Castillo P, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and ß-Thalassemia Mice. J Proteome Res. 2023 09 01; 22(9):2925-2935.
    View in: PubMed
    Score: 0.005
  193. Ohm AM, Affandi T, Reisz JA, Caino MC, D'Alessandro A, Reyland ME. Metabolic reprogramming contributes to radioprotection by protein kinase Cd. J Biol Chem. 2023 10; 299(10):105186.
    View in: PubMed
    Score: 0.005
  194. Gadwa J, Amann M, Bickett TE, Knitz MW, Darragh LB, Piper M, Van Court B, Bukkapatnam S, Pham TT, Wang XJ, Saviola AJ, Deak LC, Umaña P, Klein C, D'Alessandro A, Karam SD. Selective targeting of IL2Rß? combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC. Cell Rep Med. 2023 08 15; 4(8):101150.
    View in: PubMed
    Score: 0.005
  195. Chen C, Xie T, Zhang Y, Wang Y, Yu F, Lin L, Zhang W, Brown BC, Zhang X, Kellems RE, D'Alessandro A, Xia Y. Erythrocyte ENT1-AMPD3 Axis is an Essential Purinergic Hypoxia Sensor and Energy Regulator Combating CKD in a Mouse Model. J Am Soc Nephrol. 2023 10 01; 34(10):1647-1671.
    View in: PubMed
    Score: 0.005
  196. Cralley AL, Erickson C, Schaid TR, Hallas W, Thielen O, Mitra S, Stafford P, Hom P, Silliman C, Cohen MJ, Moore EE, D'Alessandro A, Hansen KC. The proteomic and metabolomic signatures of isolated and polytrauma traumatic brain injury. Am J Surg. 2023 12; 226(6):790-797.
    View in: PubMed
    Score: 0.005
  197. Isiksacan Z, D'Alessandro A, Wolf SM, McKenna DH, Tessier SN, Kucukal E, Gokaltun AA, William N, Sandlin RD, Bischof J, Mohandas N, Busch MP, Elbuken C, Gurkan UA, Toner M, Acker JP, Yarmush ML, Usta OB. Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine. Proc Natl Acad Sci U S A. 2023 08 08; 120(32):e2115616120.
    View in: PubMed
    Score: 0.005
  198. Coleman JR, D'Alessandro A, LaCroix I, Dzieciatkowska M, Lutz P, Mitra S, Gamboni F, Ruf W, Silliman CC, Cohen MJ. A metabolomic and proteomic analysis of pathologic hypercoagulability in traumatic brain injury patients after dura violation. J Trauma Acute Care Surg. 2023 12 01; 95(6):925-934.
    View in: PubMed
    Score: 0.005
  199. Dziewulska KH, Reisz JA, Hay AM, D'Alessandro A, Zimring JC. Hemolysis and Metabolic Lesion of G6PD Deficient RBCs in Response to Dapsone Hydroxylamine in a Humanized Mouse Model. J Pharmacol Exp Ther. 2023 09; 386(3):323-330.
    View in: PubMed
    Score: 0.005
  200. Monte AA, Vest A, Reisz JA, Berninzoni D, Hart C, Dylla L, D'Alessandro A, Heard KJ, Wood C, Pattee J. A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation. J Med Toxicol. 2023 07; 19(3):255-261.
    View in: PubMed
    Score: 0.005
  201. Bolf EL, Beadnell TC, Rose MM, D'Alessandro A, Nemkov T, Hansen KC, Schweppe RE. Dasatinib and Trametinib Promote Anti-Tumor Metabolic Activity. Cells. 2023 05 12; 12(10).
    View in: PubMed
    Score: 0.005
  202. Piper M, Hoen M, Darragh LB, Knitz MW, Nguyen D, Gadwa J, Durini G, Karakoc I, Grier A, Neupert B, Van Court B, Abdelazeem KNM, Yu J, Olimpo NA, Corbo S, Ross RB, Pham TT, Joshi M, Kedl RM, Saviola AJ, Amann M, Umaña P, Codarri Deak L, Klein C, D'Alessandro A, Karam SD. Simultaneous targeting of PD-1 and IL-2Rß? with radiation therapy inhibits pancreatic cancer growth and metastasis. Cancer Cell. 2023 05 08; 41(5):950-969.e6.
    View in: PubMed
    Score: 0.005
  203. Custer B, Bloch EM, Bryant BJ, D'Alessandro A, Delaney M, Goel R, Hod EA, Josephson CD, Katz LM, Miller YM, Sayers MH, Seheult JN, Triulzi DJ, Berger J, Zou S, Hailu B, Glynn SA, Roubinian NH. Proceedings of the 2022 NHLBI and OASH state of the science in transfusion medicine symposium. Transfusion. 2023 05; 63(5):1074-1091.
    View in: PubMed
    Score: 0.005
  204. Unali G, Crivicich G, Pagani I, Abou-Alezz M, Folchini F, Valeri E, Matafora V, Reisz JA, Giordano AMS, Cuccovillo I, Butta GM, Donnici L, D'Alessandro A, De Francesco R, Manganaro L, Cittaro D, Merelli I, Petrillo C, Bachi A, Vicenzi E, Kajaste-Rudnitski A. Interferon-inducible phospholipids govern IFITM3-dependent endosomal antiviral immunity. EMBO J. 2023 05 15; 42(10):e112234.
    View in: PubMed
    Score: 0.005
  205. Kumar S, Vassallo JD, Nattamai KJ, Hassan A, Karns R, Vollmer A, Soller K, Sakk V, Sacma M, Nemkov T, D'Alessandro A, Geiger H. pH regulates hematopoietic stem cell potential via polyamines. EMBO Rep. 2023 05 04; 24(5):e55373.
    View in: PubMed
    Score: 0.005
  206. Mian SA, Philippe C, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D, Morales V, Finch AJ, D'Alessandro A, Bianchi K, Wang J, Gallipoli P, Kordasti S, Kubasch AS, Cross M, Platzbecker U, Wiseman DH, Bonnet D, Bernard DG, Gribben JG, Rouault-Pierre K. Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia. Sci Transl Med. 2023 03; 15(685):eabn5135.
    View in: PubMed
    Score: 0.005
  207. Zhang H, D'Alessandro A, Li M, Reisz JA, Riddle S, Muralidhar A, Bull T, Zhao L, Gerasimovskaya E, Stenmark KR. Histone deacetylase inhibitors synergize with sildenafil to suppress purine metabolism and proliferation in pulmonary hypertension. Vascul Pharmacol. 2023 04; 149:107157.
    View in: PubMed
    Score: 0.005
  208. Masci VL, Stefanoni D, D'Alessandro A, Zambelli M, Modesti L, Pollini D, Ovidi E, Tiezzi A. Induction of Drug-Resistance and Production of a Culture Medium Able to Induce Drug-Resistance in Vinblastine Untreated Murine Myeloma Cells. Molecules. 2023 Feb 22; 28(5).
    View in: PubMed
    Score: 0.005
  209. DeBot M, Erickson C, Kelher M, Schaid TR, Moore EE, Sauaia A, Cralley A, LaCroix I, D'Alessandro A, Hansen K, Cohen MJ, Silliman CC, Coleman J. Platelet and cryoprecipitate transfusions from female donors improve coagulopathy in vitro. J Trauma Acute Care Surg. 2023 04 01; 94(4):497-503.
    View in: PubMed
    Score: 0.005
  210. Thangaraju K, Setua S, Lisk C, Swindle D, Stephenson D, Dzieciatkowska M, Lamb DR, Moitra P, Pak D, Hassell K, George G, Nuss R, Davizon-Castillo P, Stenmark KR, D'Alessandro A, Irwin DC, Buehler PW. Extracellular Vesicle Size Reveals Cargo Specific to Coagulation and Inflammation in Pediatric and Adult Sickle Cell Disease. Clin Appl Thromb Hemost. 2023 Jan-Dec; 29:10760296231186144.
    View in: PubMed
    Score: 0.005
  211. Hoffman MC, Hunter SJ, D'Alessandro A, Christians U, Law AJ, Freedman R. Maternal Plasma Choline during Gestation and Small for Gestational Age Infants. Am J Perinatol. 2024 05; 41(S 01):e939-e948.
    View in: PubMed
    Score: 0.005
  212. Setua S, Thangaraju K, Dzieciatkowska M, Wilkerson RB, Nemkov T, Lamb DR, Tagaya Y, Boyer T, Rowden T, Doctor A, D'Alessandro A, Buehler PW. Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma. Sci Rep. 2022 12 23; 12(1):22191.
    View in: PubMed
    Score: 0.005
  213. Recktenwald SM, Simionato G, Lopes MGM, Gamboni F, Dzieciatkowska M, Meybohm P, Zacharowski K, von Knethen A, Wagner C, Kaestner L, D'Alessandro A, Quint S. Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19. Elife. 2022 12 20; 11.
    View in: PubMed
    Score: 0.005
  214. Schaid TR, LaCroix I, Hansen KC, D'Alessandro A, Moore EE, Sauaia A, Dzieciatkowska M, DeBot M, Cralley AL, Thielen O, Hallas W, Erickson C, Mitra S, Banerjee A, Jones K, Silliman CC, Cohen MJ. A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. J Trauma Acute Care Surg. 2023 03 01; 94(3):361-370.
    View in: PubMed
    Score: 0.005
  215. Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC. Nat Cancer. 2022 11; 3(11):1300-1317.
    View in: PubMed
    Score: 0.005
  216. Schaid TR, Cohen MJ, D'Alessandro A, Silliman CC, Moore EE, Sauaia A, Dzieciatkowska M, Hallas W, Thielen O, DeBot M, Cralley A, LaCroix I, Erickson C, Mitra S, Banerjee A, Jones K, Hansen KC. TRAUMA INDUCES INTRAVASCULAR HEMOLYSIS, EXACERBATED BY RED BLOOD CELL TRANSFUSION AND ASSOCIATED WITH DISRUPTED ARGININE-NITRIC OXIDE METABOLISM. Shock. 2023 01 01; 59(1):12-19.
    View in: PubMed
    Score: 0.005
  217. Moore A, Busch MP, Dziewulska K, Francis RO, Hod EA, Zimring JC, D'Alessandro A, Page GP. Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors. J Biol Chem. 2022 12; 298(12):102706.
    View in: PubMed
    Score: 0.005
  218. Liao Y, Luo Z, Lin Y, Chen H, Chen T, Xu L, Orgurek S, Berry K, Dzieciatkowska M, Reisz JA, D'Alessandro A, Zhou W, Lu QR. PRMT3 drives glioblastoma progression by enhancing HIF1A and glycolytic metabolism. Cell Death Dis. 2022 11 09; 13(11):943.
    View in: PubMed
    Score: 0.005
  219. Roma A, Tcheng M, Ahmed N, Walker S, Jayanth P, Minden MD, Hope K, Nekkar Rao PP, Luc J, Doxey AC, Reisz JA, Culp-Hill R, D'Alessandro A, Spagnuolo PA. Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia. Mol Cancer Res. 2022 11 03; 20(11):1659-1673.
    View in: PubMed
    Score: 0.005
  220. Hadley JB, Kelher MR, D'Alessandro A, Gamboni F, Hansen K, Coleman J, Jones K, Cohen M, Moore EE, Banerjee A, Silliman CC. A pilot study of the metabolic profiles of apheresis platelets modified by donor age and sex and in vitro short-term incubation with sex hormones. Transfusion. 2022 12; 62(12):2596-2608.
    View in: PubMed
    Score: 0.005
  221. Rabcuka J, Blonski S, Meli A, Sowemimo-Coker S, Zaremba D, Stephenson D, Dzieciatkowska M, Nerguizian D, Cardigan R, Korczyk PM, Smethurst PA, D'Alessandro A, Swietach P. Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells. Blood Adv. 2022 09 27; 6(18):5415-5428.
    View in: PubMed
    Score: 0.005
  222. Traxler L, Herdy JR, Stefanoni D, Eichhorner S, Pelucchi S, Szücs A, Santagostino A, Kim Y, Agarwal RK, Schlachetzki JCM, Glass CK, Lagerwall J, Galasko D, Gage FH, D'Alessandro A, Mertens J. Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metab. 2022 09 06; 34(9):1248-1263.e6.
    View in: PubMed
    Score: 0.005
  223. Lee E, Redzic JS, Nemkov T, Saviola AJ, Dzieciatkowska M, Hansen KC, D'Alessandro A, Dinarello C, Eisenmesser EZ. Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions. Molecules. 2022 Jul 14; 27(14).
    View in: PubMed
    Score: 0.005
  224. de Bruin S, Peters AL, Wijnberge M, van Baarle FEHP, AbdelRahman AHA, Vermeulen C, Beuger BM, Reisz JA, D'Alessandro A, Vlaar APJ, de Korte D, van Bruggen R. Storage of red blood cells in alkaline PAGGGM improves metabolism but has no effect on recovery after transfusion. Blood Adv. 2022 07 12; 6(13):3899-3910.
    View in: PubMed
    Score: 0.005
  225. McClary WD, Catala A, Zhang W, Gamboni F, Dzieciatkowska M, Sidhu SS, D'Alessandro A, Catalano CE. A Designer Nanoparticle Platform for Controlled Intracellular Delivery of Bioactive Macromolecules: Inhibition of Ubiquitin-Specific Protease 7 in Breast Cancer Cells. ACS Chem Biol. 2022 07 15; 17(7):1853-1865.
    View in: PubMed
    Score: 0.005
  226. Arnold CG, Dylla L, Monte AA, Heard K, Heard S, D'Alessandro A, Reynolds K, Dart R, Rumack B, Sonn B. Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences. J Med Toxicol. 2022 10; 18(4):297-310.
    View in: PubMed
    Score: 0.005
  227. Guard SE, Chapnick DA, Poss ZC, Ebmeier CC, Jacobsen J, Nemkov T, Ball KA, Webb KJ, Simpson HL, Coleman S, Bunker E, Ramirez A, Reisz JA, Sievers R, Stowell MHB, D'Alessandro A, Liu X, Old WM. Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines. Mol Cell Proteomics. 2022 10; 21(10):100262.
    View in: PubMed
    Score: 0.005
  228. Moriconi C, Dzieciatkowska M, Roy M, D'Alessandro A, Roingeard P, Lee JY, Gibb DR, Tredicine M, McGill MA, Qiu A, La Carpia F, Francis RO, Hod EA, Thomas T, Picard M, Akpan IJ, Luckey CJ, Zimring JC, Spitalnik SL, Hudson KE. Retention of functional mitochondria in mature red blood cells from patients with sickle cell disease. Br J Haematol. 2022 08; 198(3):574-586.
    View in: PubMed
    Score: 0.005
  229. Mandala A, Dobrinskikh E, Janssen RC, Fiehn O, D'Alessandro A, Friedman JE, Jonscher KR. Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD. Int J Mol Sci. 2022 May 27; 23(11).
    View in: PubMed
    Score: 0.005
  230. Schaid TR, Hansen KC, Sauaia A, Moore EE, DeBot M, Cralley AL, Erickson C, Silliman CC, Banerjee A, Ghasabyan A, Jones K, Lacroix I, Mitra S, D'Alessandro A, Cohen MJ. Postinjury complement C4 activation is associated with adverse outcomes and is potentially influenced by plasma resuscitation. J Trauma Acute Care Surg. 2022 11 01; 93(5):588-596.
    View in: PubMed
    Score: 0.005
  231. Vigers T, Vinovskis C, Li LP, Prasad P, Heerspink H, D'Alessandro A, Reisz JA, Piani F, Cherney DZ, van Raalte DH, Nadeau KJ, Pavkov ME, Nelson RG, Pyle L, Bjornstad P. Plasma levels of carboxylic acids are markers of early kidney dysfunction in young people with type 1 diabetes. Pediatr Nephrol. 2023 01; 38(1):193-202.
    View in: PubMed
    Score: 0.005
  232. Song A, Wen AQ, Wen YE, Dzieciatkowska M, Kellems RE, Juneja HS, D'Alessandro A, Xia Y. p97 dysfunction underlies a loss of quality control of damaged membrane proteins and promotes oxidative stress and sickling in sickle cell disease. FASEB J. 2022 05; 36(5):e22246.
    View in: PubMed
    Score: 0.005
  233. Ferrero E, Villa A, Stefanoni D, Nemkov T, D'Alessandro A, Tengesdal I, Belloni D, Molteni R, Vergani B, De Luca G, Grassini G, Cangi MG, Dagna L, Doglioni C, Cavalli G, Ferrarini M. Immunometabolic activation of macrophages leads to cytokine production in the pathogenesis of KRAS-mutated histiocytosis. Rheumatology (Oxford). 2022 04 11; 61(4):e93-e96.
    View in: PubMed
    Score: 0.005
  234. Galbraith MD, Kinning KT, Sullivan KD, Araya P, Smith KP, Granrath RE, Shaw JR, Baxter R, Jordan KR, Russell S, Dzieciatkowska M, Reisz JA, Gamboni F, Cendali F, Ghosh T, Guo K, Wilson CC, Santiago ML, Monte AA, Bennett TD, Hansen KC, Hsieh EWY, D'Alessandro A, Espinosa JM. Specialized interferon action in COVID-19. Proc Natl Acad Sci U S A. 2022 03 15; 119(11).
    View in: PubMed
    Score: 0.005
  235. Giordano AMS, Luciani M, Gatto F, Abou Alezz M, Beghè C, Della Volpe L, Migliara A, Valsoni S, Genua M, Dzieciatkowska M, Frati G, Tahraoui-Bories J, Giliani SC, Orcesi S, Fazzi E, Ostuni R, D'Alessandro A, Di Micco R, Merelli I, Lombardo A, Reijns MAM, Gromak N, Gritti A, Kajaste-Rudnitski A. DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes. J Exp Med. 2022 04 04; 219(4).
    View in: PubMed
    Score: 0.005
  236. Butera A, Roy M, Zampieri C, Mammarella E, Panatta E, Melino G, D'Alessandro A, Amelio I. p53-driven lipidome influences non-cell-autonomous lysophospholipids in pancreatic cancer. Biol Direct. 2022 03 08; 17(1):6.
    View in: PubMed
    Score: 0.005
  237. Xu P, Chen C, Zhang Y, Dzieciatkowska M, Brown BC, Zhang W, Xie T, Abdulmalik O, Song A, Tong C, Qi H, Roach R, Kellems RE, D'Alessandro A, Xia Y. Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis. Cell Metab. 2022 02 01; 34(2):299-316.e6.
    View in: PubMed
    Score: 0.005
  238. Amaya ML, Inguva A, Pei S, Jones C, Krug A, Ye H, Minhajuddin M, Winters A, Furtek SL, Gamboni F, Stevens B, D'Alessandro A, Pollyea DA, Reigan P, Jordan CT. The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation. Blood. 2022 01 27; 139(4):584-596.
    View in: PubMed
    Score: 0.005
  239. McCubbrey AL, McManus SA, McClendon JD, Thomas SM, Chatwin HB, Reisz JA, D'Alessandro A, Mould KJ, Bratton DL, Henson PM, Janssen WJ. Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells. Cell Rep. 2022 01 11; 38(2):110222.
    View in: PubMed
    Score: 0.005
  240. Tzounakas VL, Anastasiadi AT, Stefanoni D, Cendali F, Bertolone L, Gamboni F, Dzieciatkowska M, Rousakis P, Vergaki A, Soulakis V, Tsitsilonis OE, Stamoulis K, Papassideri IS, Kriebardis AG, D'Alessandro A, Antonelou MH. Beta thalassemia minor is a beneficial determinant of red blood cell storage lesion. Haematologica. 2022 01 01; 107(1):112-125.
    View in: PubMed
    Score: 0.005
  241. Donovan K, Meli A, Cendali F, Park KC, Cardigan R, Stanworth S, McKechnie S, D'Alessandro A, Smethurst PA, Swietach P. Stored blood has compromised oxygen unloading kinetics that can be normalized with rejuvenation and predicted from corpuscular side-scatter. Haematologica. 2022 01 01; 107(1):298-302.
    View in: PubMed
    Score: 0.005
  242. Snyder JP, Gullickson SK, Del Rio-Guerra R, Sweezy A, Vagher B, Hogan TC, Lahue KG, Reisz JA, D'Alessandro A, Krementsov DN, Amiel E. Divergent Genetic Regulation of Nitric Oxide Production between C57BL/6J and Wild-Derived PWD/PhJ Mice Controls Postactivation Mitochondrial Metabolism, Cell Survival, and Bacterial Resistance in Dendritic Cells. J Immunol. 2022 01 01; 208(1):97-109.
    View in: PubMed
    Score: 0.005
  243. Anastasiadi AT, Paronis EC, Arvaniti VZ, Velentzas AD, Apostolidou AC, Balafas EG, Dzieciatkowska M, Kostomitsopoulos NG, Stamoulis K, Papassideri IS, D'Alessandro A, Kriebardis AG, Antonelou MH, Tzounakas VL. The Post-Storage Performance of RBCs from Beta-Thalassemia Trait Donors Is Related to Their Storability Profile. Int J Mol Sci. 2021 Nov 13; 22(22).
    View in: PubMed
    Score: 0.005
  244. Himbert S, Qadri SM, Sheffield WP, Schubert P, D'Alessandro A, Rheinstädter MC. Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity. PLoS One. 2021; 16(11):e0259267.
    View in: PubMed
    Score: 0.005
  245. Kumar S, Frid MG, Zhang H, Li M, Riddle S, Brown RD, Yadav SC, Roy MK, Dzieciatkowska ME, D'Alessandro A, Hansen KC, Stenmark KR. Complement-containing small extracellular vesicles from adventitial fibroblasts induce proinflammatory and metabolic reprogramming in macrophages. JCI Insight. 2021 11 08; 6(21).
    View in: PubMed
    Score: 0.005
  246. Molteni R, Biavasco R, Stefanoni D, Nemkov T, Domínguez-Andrés J, Arts RJ, Merelli I, Mazza D, Zambrano S, Panigada M, Cantoni E, Tengesdal IW, Maksud P, Piras F, Cesana D, Cassina L, Distefano G, Loffreda A, Gnani D, De Luca G, Tomelleri A, Campochiaro C, Joosten LAB, Dinarello CA, Kajaste-Rudnitski A, Haroche J, Cardaci S, Cenci S, Dagna L, Doglioni C, Ferrarini M, Ferrero E, Boletta A, D'Alessandro A, Montini E, Netea MG, Cavalli G. Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease. Blood. 2021 10 28; 138(17):1554-1569.
    View in: PubMed
    Score: 0.005
  247. van de Wetering C, Manuel AM, Sharafi M, Aboushousha R, Qian X, Erickson C, MacPherson M, Chan G, Adcock IM, ZounematKermani N, Schleich F, Louis R, Bohrnsen E, D'Alessandro A, Wouters EF, Reynaert NL, Li J, Wolf CR, Henderson CJ, Lundblad LKA, Poynter ME, Dixon AE, Irvin CG, van der Vliet A, van der Velden JL, Janssen-Heininger YM. Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2. Redox Biol. 2021 11; 47:102160.
    View in: PubMed
    Score: 0.005
  248. Bissinger R, Nemkov T, D'Alessandro A, Grau M, Dietz T, Bohnert BN, Essigke D, Wörn M, Schaefer L, Xiao M, Beirne JM, Kalo MZ, Schork A, Bakchoul T, Omage K, Kong L, Gonzalez-Menendez I, Quintanilla-Martinez L, Fehrenbacher B, Schaller M, Dhariwal A, Birkenfeld AL, Grahammer F, Qadri SM, Artunc F. Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism. Kidney Int. 2021 12; 100(6):1227-1239.
    View in: PubMed
    Score: 0.005
  249. Jezewski AJ, Lin YH, Reisz JA, Culp-Hill R, Barekatain Y, Yan VC, D'Alessandro A, Muller FL, Odom John AR. Targeting Host Glycolysis as a Strategy for Antimalarial Development. Front Cell Infect Microbiol. 2021; 11:730413.
    View in: PubMed
    Score: 0.005
  250. Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. NF-?B Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis. Hepatology. 2021 12; 74(6):3284-3300.
    View in: PubMed
    Score: 0.005
  251. Traxler L, Lagerwall J, Eichhorner S, Stefanoni D, D'Alessandro A, Mertens J. Metabolism navigates neural cell fate in development, aging and neurodegeneration. Dis Model Mech. 2021 08 01; 14(8).
    View in: PubMed
    Score: 0.005
  252. Sullivan KD, Galbraith MD, Kinning KT, Bartsch KW, Levinsky NC, Araya P, Smith KP, Granrath RE, Shaw JR, Baxter RM, Jordan KR, Russell SA, Dzieciatkowska ME, Reisz JA, Gamboni F, Cendali FI, Ghosh T, Monte AA, Bennett TD, Miller MG, Hsieh EW, D'Alessandro A, Hansen KC, Espinosa JM. The COVIDome Explorer researcher portal. Cell Rep. 2021 08 17; 36(7):109527.
    View in: PubMed
    Score: 0.005
  253. Clement CC, D'Alessandro A, Thangaswamy S, Chalmers S, Furtado R, Spada S, Mondanelli G, Ianni F, Gehrke S, Gargaro M, Manni G, Cara LCL, Runge P, Tsai WL, Karaman S, Arasa J, Fernandez-Rodriguez R, Beck A, Macchiarulo A, Gadina M, Halin C, Fallarino F, Skobe M, Veldhoen M, Moretti S, Formenti S, Demaria S, Soni RK, Galarini R, Sardella R, Lauvau G, Putterman C, Alitalo K, Grohmann U, Santambrogio L. 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine. Nat Commun. 2021 07 21; 12(1):4447.
    View in: PubMed
    Score: 0.005
  254. Subedi A, Liu Q, Ayyathan DM, Sharon D, Cathelin S, Hosseini M, Xu C, Voisin V, Bader GD, D'Alessandro A, Lechman ER, Dick JE, Minden MD, Wang JCY, Chan SM. Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis. Cell Stem Cell. 2021 10 07; 28(10):1851-1867.e8.
    View in: PubMed
    Score: 0.005
  255. Hunter SK, Hoffman MC, McCarthy L, D'Alessandro A, Wyrwa A, Noonan K, Christians U, Nakimuli-Mpungu E, Zeisel SH, Law AJ, Freedman R. Black American Maternal Prenatal Choline, Offspring Gestational Age at Birth, and Developmental Predisposition to Mental Illness. Schizophr Bull. 2021 07 08; 47(4):896-905.
    View in: PubMed
    Score: 0.005
  256. Hunter SK, Hoffman MC, McCarthy L, D'Alessandro A, Wyrwa A, Noonan K, Christians U, Nakimuli-Mpungu E, Zeisel SH, Law AJ, Freedman R. Targeting Treatments to Health Disparities. Schizophr Bull. 2021 07 08; 47(4):886-887.
    View in: PubMed
    Score: 0.005
  257. Catala A, Dzieciatkowska M, Wang G, Gutierrez-Hartmann A, Simberg D, Hansen KC, D'Alessandro A, Catalano CE. Targeted Intracellular Delivery of Trastuzumab Using Designer Phage Lambda Nanoparticles Alters Cellular Programs in Human Breast Cancer Cells. ACS Nano. 2021 Jul 27; 15(7):11789-11805.
    View in: PubMed
    Score: 0.005
  258. Craighead DH, Heinbockel TC, Freeberg KA, Rossman MJ, Jackman RA, Jankowski LR, Hamilton MN, Ziemba BP, Reisz JA, D'Alessandro A, Brewster LM, DeSouza CA, You Z, Chonchol M, Bailey EF, Seals DR. Time-Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above-Normal Blood Pressure. J Am Heart Assoc. 2021 07 06; 10(13):e020980.
    View in: PubMed
    Score: 0.005
  259. Tcheng M, Roma A, Ahmed N, Smith RW, Jayanth P, Minden MD, Schimmer AD, Hess DA, Hope K, Rea KA, Akhtar TA, Bohrnsen E, D'Alessandro A, Mohsen AW, Vockley J, Spagnuolo PA. Very long chain fatty acid metabolism is required in acute myeloid leukemia. Blood. 2021 06 24; 137(25):3518-3532.
    View in: PubMed
    Score: 0.005
  260. Joshi SK, Nechiporuk T, Bottomly D, Piehowski PD, Reisz JA, Pittsenbarger J, Kaempf A, Gosline SJC, Wang YT, Hansen JR, Gritsenko MA, Hutchinson C, Weitz KK, Moon J, Cendali F, Fillmore TL, Tsai CF, Schepmoes AA, Shi T, Arshad OA, McDermott JE, Babur O, Watanabe-Smith K, Demir E, D'Alessandro A, Liu T, Tognon CE, Tyner JW, McWeeney SK, Rodland KD, Druker BJ, Traer E. The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance. Cancer Cell. 2021 07 12; 39(7):999-1014.e8.
    View in: PubMed
    Score: 0.005
  261. Redzic JS, Lee E, Born A, Issaian A, Henen MA, Nichols PJ, Blue A, Hansen KC, D'Alessandro A, Vögeli B, Eisenmesser EZ. The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region. J Mol Biol. 2021 07 23; 433(15):167108.
    View in: PubMed
    Score: 0.005
  262. Hunter SK, Hoffman MC, D'Alessandro A, Walker VK, Balser M, Noonan K, Law AJ, Freedman R. Maternal prenatal choline and inflammation effects on 4-year-olds' performance on the Wechsler Preschool and Primary Scale of Intelligence-IV. J Psychiatr Res. 2021 09; 141:50-56.
    View in: PubMed
    Score: 0.005
  263. Anderson CC, Marentette JO, Prutton KM, Rauniyar AK, Reisz JA, D'Alessandro A, Maclean KN, Saba LM, Roede JR. Trisomy 21 results in modest impacts on mitochondrial function and central carbon metabolism. Free Radic Biol Med. 2021 08 20; 172:201-212.
    View in: PubMed
    Score: 0.005
  264. Tcheng M, Cunha VLS, Ahmed N, Liu X, Smith RW, Rea KA, Akhtar TA, D'Alessandro A, Minden MD, Vockley J, O'Doherty GA, Lowary TL, Spagnuolo PA. Structure-activity relationship of avocadyne. Food Funct. 2021 Jul 21; 12(14):6323-6333.
    View in: PubMed
    Score: 0.005
  265. Sonn BJ, Heard KJ, Heard SM, D'Alessandro A, Reynolds KM, Dart RC, Rumack BH, Monte AA. Metabolomic markers predictive of hepatic adaptation to therapeutic dosing of acetaminophen. Clin Toxicol (Phila). 2022 Feb; 60(2):221-230.
    View in: PubMed
    Score: 0.005
  266. Giddings EL, Champagne DP, Wu MH, Laffin JM, Thornton TM, Valenca-Pereira F, Culp-Hill R, Fortner KA, Romero N, East J, Cao P, Arias-Pulido H, Sidhu KS, Silverstrim B, Kam Y, Kelley S, Pereira M, Bates SE, Bunn JY, Fiering SN, Matthews DE, Robey RW, Stich D, D'Alessandro A, Rincon M. Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance. Nat Commun. 2021 05 14; 12(1):2804.
    View in: PubMed
    Score: 0.004
  267. Rogers SC, Ge X, Brummet M, Lin X, Timm DD, d'Avignon A, Garbow JR, Kao J, Prakash J, Issaian A, Eisenmesser EZ, Reisz JA, D'Alessandro A, Doctor A. Quantifying dynamic range in red blood cell energetics: Evidence of progressive energy failure during storage. Transfusion. 2021 05; 61(5):1586-1599.
    View in: PubMed
    Score: 0.004
  268. Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, Dagna L, Boletta A, D'Alessandro A, Joosten LAB, Netea MG, Dinarello CA. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity. Cell Rep. 2021 04 06; 35(1):108955.
    View in: PubMed
    Score: 0.004
  269. Tzounakas VL, Anastasiadi AT, Dzieciatkowska M, Karadimas DG, Stamoulis K, Papassideri IS, Hansen KC, D'Alessandro A, Kriebardis AG, Antonelou MH. Proteome of Stored RBC Membrane and Vesicles from Heterozygous Beta Thalassemia Donors. Int J Mol Sci. 2021 Mar 25; 22(7).
    View in: PubMed
    Score: 0.004
  270. Esquer H, Zhou Q, Nemkov T, Abraham AD, Rinaldetti S, Chen YC, Zhang X, Orman MV, D'Alessandro A, Ferrer M, Messersmith WA, LaBarbera DV. Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer. Oncogene. 2021 04; 40(16):2884-2897.
    View in: PubMed
    Score: 0.004
  271. Galbraith MD, Kinning KT, Sullivan KD, Baxter R, Araya P, Jordan KR, Russell S, Smith KP, Granrath RE, Shaw JR, Dzieciatkowska M, Ghosh T, Monte AA, D'Alessandro A, Hansen KC, Benett TD, Hsieh EW, Espinosa JM. Seroconversion stages COVID19 into distinct pathophysiological states. Elife. 2021 03 16; 10.
    View in: PubMed
    Score: 0.004
  272. Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, Pietras EM, DeGregori J, Tan AC, Joosten LAB, Fujita M, Dinarello CA, Marchetti C. Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
    View in: PubMed
    Score: 0.004
  273. Broussard JL, Perreault L, Macias E, Newsom SA, Harrison K, Bui HH, Milligan P, Roth KD, Nemkov T, D'Alessandro A, Brozinick JT, Bergman BC. Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. Obesity (Silver Spring). 2021 03; 29(3):550-561.
    View in: PubMed
    Score: 0.004
  274. Rossman MJ, Gioscia-Ryan RA, Santos-Parker JR, Ziemba BP, Lubieniecki KL, Johnson LC, Poliektov NE, Bispham NZ, Woodward KA, Nagy EE, Bryan NS, Reisz JA, D'Alessandro A, Chonchol M, Sindler AL, Seals DR. Inorganic Nitrite Supplementation Improves Endothelial Function With Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress. Hypertension. 2021 04; 77(4):1212-1222.
    View in: PubMed
    Score: 0.004
  275. Knight WE, Cao Y, Lin YH, Chi C, Bai B, Sparagna GC, Zhao Y, Du Y, Londono P, Reisz JA, Brown BC, Taylor MRG, Ambardekar AV, Cleveland JC, McKinsey TA, Jeong MY, Walker LA, Woulfe KC, D'Alessandro A, Chatfield KC, Xu H, Bristow MR, Buttrick PM, Song K. Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy. Stem Cell Reports. 2021 03 09; 16(3):519-533.
    View in: PubMed
    Score: 0.004
  276. Oatman N, Dasgupta N, Arora P, Choi K, Gawali MV, Gupta N, Parameswaran S, Salomone J, Reisz JA, Lawler S, Furnari F, Brennan C, Wu J, Sallans L, Gudelsky G, Desai P, Gebelein B, Weirauch MT, D'Alessandro A, Komurov K, Dasgupta B. Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer. Sci Adv. 2021 02; 7(7).
    View in: PubMed
    Score: 0.004
  277. Nemkov T, Stefanoni D, Bordbar A, Issaian A, Palsson BO, Dumont LJ, Hay A, Song A, Xia Y, Redzic JS, Eisenmesser EZ, Zimring JC, Kleinman S, Hansen KC, Busch MP, D'Alessandro A. Blood donor exposome and impact of common drugs on red blood cell metabolism. JCI Insight. 2021 02 08; 6(3).
    View in: PubMed
    Score: 0.004
  278. Hunter SK, Hoffman MC, D'Alessandro A, Wyrwa A, Noonan K, Zeisel SH, Law AJ, Freedman R. Prenatal choline, cannabis, and infection, and their association with offspring development of attention and social problems through 4 years of age. Psychol Med. 2022 10; 52(14):3019-3028.
    View in: PubMed
    Score: 0.004
  279. Dong S, Wang Q, Kao YR, Diaz A, Tasset I, Kaushik S, Thiruthuvanathan V, Zintiridou A, Nieves E, Dzieciatkowska M, Reisz JA, Gavathiotis E, D'Alessandro A, Will B, Cuervo AM. Chaperone-mediated autophagy sustains haematopoietic stem-cell function. Nature. 2021 03; 591(7848):117-123.
    View in: PubMed
    Score: 0.004
  280. Dhagia V, Kitagawa A, Jacob C, Zheng C, D'Alessandro A, Edwards JG, Rocic P, Gupte R, Gupte SA. G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases. Am J Physiol Heart Circ Physiol. 2021 03 01; 320(3):H999-H1016.
    View in: PubMed
    Score: 0.004
  281. McKinney C, Ellison M, Briones NJ, Baroffio A, Murphy J, Tran AD, Reisz JA, D'Alessandro A, Ambruso DR. Metabolic abnormalities in G6PC3-deficient human neutrophils result in severe functional defects. Blood Adv. 2020 12 08; 4(23):5888-5901.
    View in: PubMed
    Score: 0.004
  282. Anderson CC, Marentette JO, Rauniyar AK, Prutton KM, Khatri M, Matheson C, Reisz JA, Reigan P, D'Alessandro A, Roede JR. Maneb alters central carbon metabolism and thiol redox status in a toxicant model of Parkinson's disease. Free Radic Biol Med. 2021 01; 162:65-76.
    View in: PubMed
    Score: 0.004
  283. Henriksen HH, McGarrity S, SigurÐardóttir RS, Nemkov T, D'Alessandro A, Palsson BO, Stensballe J, Wade CE, Rolfsson Ó, Johansson PI. Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma: A New Research Paradigm. Ann Surg. 2020 12; 272(6):1140-1148.
    View in: PubMed
    Score: 0.004
  284. Lonnemann N, Hosseini S, Marchetti C, Skouras DB, Stefanoni D, D'Alessandro A, Dinarello CA, Korte M. The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2020 12 15; 117(50):32145-32154.
    View in: PubMed
    Score: 0.004
  285. Tzounakas VL, Dzieciatkowska M, Anastasiadi AT, Karadimas DG, Vergaki A, Siourounis P, Stamoulis K, Papassideri IS, Kriebardis AG, D'Alessandro A, Antonelou MH. Red cell proteasome modulation by storage, redox metabolism and transfusion. Blood Transfus. 2022 01; 20(1):27-39.
    View in: PubMed
    Score: 0.004
  286. Hazegh K, Fang F, Bravo MD, Tran JQ, Muench MO, Jackman RP, Roubinian N, Bertolone L, D'Alessandro A, Dumont L, Page GP, Kanias T. Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress. Transfusion. 2021 02; 61(2):435-448.
    View in: PubMed
    Score: 0.004
  287. Culp-Hill R, D'Alessandro A, Pietras EM. Extinguishing the Embers: Targeting AML Metabolism. Trends Mol Med. 2021 04; 27(4):332-344.
    View in: PubMed
    Score: 0.004
  288. Stevens BM, Jones CL, Pollyea DA, Culp-Hill R, D'Alessandro A, Winters A, Krug A, Abbott D, Goosman M, Pei S, Ye H, Gillen AE, Becker MW, Savona MR, Smith C, Jordan CT. Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells. Nat Cancer. 2020 12; 1(12):1176-1187.
    View in: PubMed
    Score: 0.004
  289. Montgomery TL, Künstner A, Kennedy JJ, Fang Q, Asarian L, Culp-Hill R, D'Alessandro A, Teuscher C, Busch H, Krementsov DN. Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27516-27527.
    View in: PubMed
    Score: 0.004
  290. Alexander K, Hazegh K, Fang F, Sinchar D, Kiss JE, Page GP, D'Alessandro A, Kanias T. Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage. Transfusion. 2021 01; 61(1):108-123.
    View in: PubMed
    Score: 0.004
  291. Ye H, Minhajuddin M, Krug A, Pei S, Chou CH, Culp-Hill R, Ponder J, De Bloois E, Schniedewind B, Amaya ML, Inguva A, Stevens BM, Pollyea DA, Christians U, Grimes HL, D'Alessandro A, Jordan CT. The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG. Cancer Discov. 2021 02; 11(2):500-519.
    View in: PubMed
    Score: 0.004
  292. D'alessandro AM, Hoffmann RM, Knechtle SJ, Odorico JS, Becker YT, Musat A, Pirsch JD, Sollinger HW, Kalayoglu M. Liver transplantation from controlled non-heart-beating donors. Surgery. 2000 Oct; 128(4):579-88.
    View in: PubMed
    Score: 0.004
  293. Burchill MA, Finlon JM, Goldberg AR, Gillen AE, Dahms PA, McMahan RH, Tye A, Winter AB, Reisz JA, Bohrnsen E, Schafer JB, D'Alessandro A, Orlicky DJ, Kriss MS, Rosen HR, McCullough RL, Jirón Tamburini BA. Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System. Cell Mol Gastroenterol Hepatol. 2021; 11(2):573-595.
    View in: PubMed
    Score: 0.004
  294. Jones CL, Stevens BM, Pollyea DA, Culp-Hill R, Reisz JA, Nemkov T, Gehrke S, Gamboni F, Krug A, Winters A, Pei S, Gustafson A, Ye H, Inguva A, Amaya M, Minhajuddin M, Abbott D, Becker MW, DeGregori J, Smith CA, D'Alessandro A, Jordan CT. Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells. Cell Stem Cell. 2020 11 05; 27(5):748-764.e4.
    View in: PubMed
    Score: 0.004
  295. Mykhailova O, Olafson C, Turner TR, D'Alessandro A, Acker JP. Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity. Transfusion. 2020 11; 60(11):2633-2646.
    View in: PubMed
    Score: 0.004
  296. Freedman R, Hunter SK, Law AJ, D'Alessandro A, Noonan K, Wyrwa A, Camille Hoffman M. Maternal choline and respiratory coronavirus effects on fetal brain development. J Psychiatr Res. 2020 09; 128:1-4.
    View in: PubMed
    Score: 0.004
  297. Stefanoni D, Fu X, Reisz JA, Kanias T, Nemkov T, Page GP, Dumont L, Roubinian N, Stone M, Kleinman S, Busch M, Zimring JC, D'Alessandro A. Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers. Transfusion. 2020 06; 60(6):1160-1174.
    View in: PubMed
    Score: 0.004
  298. Francis RO, D'Alessandro A, Eisenberger A, Soffing M, Yeh R, Coronel E, Sheikh A, Rapido F, La Carpia F, Reisz JA, Gehrke S, Nemkov T, Thomas T, Schwartz J, Divgi C, Kessler D, Shaz BH, Ginzburg Y, Zimring JC, Spitalnik SL, Hod EA. Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion. J Clin Invest. 2020 05 01; 130(5):2270-2285.
    View in: PubMed
    Score: 0.004
  299. Zhou H, Blevins MA, Hsu JY, Kong D, Galbraith MD, Goodspeed A, Culp-Hill R, Oliphant MUJ, Ramirez D, Zhang L, Trinidad-Pineiro J, Mathews Griner L, King R, Barnaeva E, Hu X, Southall NT, Ferrer M, Gustafson DL, Regan DP, D'Alessandro A, Costello JC, Patnaik S, Marugan J, Zhao R, Ford HL. Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis. Cancer Res. 2020 06 15; 80(12):2689-2702.
    View in: PubMed
    Score: 0.004
  300. Xie T, Chen C, Peng Z, Brown BC, Reisz JA, Xu P, Zhou Z, Song A, Zhang Y, Bogdanov MV, Kellems RE, D'Alessandro A, Zhang W, Xia Y. Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies. Circ Res. 2020 07 17; 127(3):360-375.
    View in: PubMed
    Score: 0.004
  301. Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, Prives C, Stockwell BR. MDM2 and MDMX promote ferroptosis by PPARa-mediated lipid remodeling. Genes Dev. 2020 04 01; 34(7-8):526-543.
    View in: PubMed
    Score: 0.004
  302. Pei S, Pollyea DA, Gustafson A, Stevens BM, Minhajuddin M, Fu R, Riemondy KA, Gillen AE, Sheridan RM, Kim J, Costello JC, Amaya ML, Inguva A, Winters A, Ye H, Krug A, Jones CL, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers JR, Ashton JM, Nemkov T, D'Alessandro A, Gutman JA, Ramsey HE, Savona MR, Smith CA, Jordan CT. Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia. Cancer Discov. 2020 04; 10(4):536-551.
    View in: PubMed
    Score: 0.004
  303. Hunter SK, Hoffman MC, D'Alessandro A, Noonan K, Wyrwa A, Freedman R, Law AJ. Male fetus susceptibility to maternal inflammation: C-reactive protein and brain development. Psychol Med. 2021 02; 51(3):450-459.
    View in: PubMed
    Score: 0.004
  304. Yan D, Franzini A, Pomicter AD, Halverson BJ, Antelope O, Mason CC, Ahmann JM, Senina AV, Vellore NA, Jones CL, Zabriskie MS, Than H, Xiao MJ, van Scoyk A, Patel AB, Clair PM, Heaton WL, Owen SC, Andersen JL, Egbert CM, Reisz JA, D'Alessandro A, Cox JE, Gantz KC, Redwine HM, Iyer SM, Khorashad JS, Rajabi N, Olsen CA, O'Hare T, Deininger MW. SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA. Blood Cancer Discov. 2021 05; 2(3):266-287.
    View in: PubMed
    Score: 0.004
  305. Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR. Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice. Aging Cell. 2020 01; 19(1):e13074.
    View in: PubMed
    Score: 0.004
  306. Abraham AD, Esquer H, Zhou Q, Tomlinson N, Hamill BD, Abbott JM, Li L, Pike LA, Rinaldetti S, Ramirez DA, Lunghofer PJ, Gomez JD, Schaack J, Nemkov T, D'Alessandro A, Hansen KC, Gustafson DL, Messersmith WA, LaBarbera DV. Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer. J Med Chem. 2019 11 27; 62(22):10182-10203.
    View in: PubMed
    Score: 0.004
  307. Johnson LC, Parker K, Aguirre BF, Nemkov TG, D'Alessandro A, Johnson SA, Seals DR, Martens CR. The plasma metabolome as a predictor of biological aging in humans. Geroscience. 2019 12; 41(6):895-906.
    View in: PubMed
    Score: 0.004
  308. Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors. Nat Commun. 2019 10 18; 10(1):4766.
    View in: PubMed
    Score: 0.004
  309. Sonn BJ, Saben JL, McWilliams G, Shelton SK, Flaten HK, D'Alessandro A, Monte AA. Predicting response to lisinopril in treating hypertension: a pilot study. Metabolomics. 2019 10 03; 15(10):133.
    View in: PubMed
    Score: 0.004
  310. Hoffman MC, Hunter SK, D'Alessandro A, Noonan K, Wyrwa A, Freedman R. Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring. Psychol Med. 2020 07; 50(10):1716-1726.
    View in: PubMed
    Score: 0.004
  311. Jones CL, Stevens BM, D'Alessandro A, Culp-Hill R, Reisz JA, Pei S, Gustafson A, Khan N, DeGregori J, Pollyea DA, Jordan CT. Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II. Blood. 2019 07 25; 134(4):389-394.
    View in: PubMed
    Score: 0.004
  312. Gaikwad H, Wang G, Smith WJ, Alexander KL, D'Alessandro A, Zhang W, Purev E, Simberg D. Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes. Bioconjug Chem. 2019 08 21; 30(8):2106-2114.
    View in: PubMed
    Score: 0.004
  313. Nechiporuk T, Kurtz SE, Nikolova O, Liu T, Jones CL, D'Alessandro A, Culp-Hill R, d'Almeida A, Joshi SK, Rosenberg M, Tognon CE, Danilov AV, Druker BJ, Chang BH, McWeeney SK, Tyner JW. The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells. Cancer Discov. 2019 07; 9(7):910-925.
    View in: PubMed
    Score: 0.004
  314. Schmitt LR, Henderson R, Barrett A, Darula Z, Issaian A, D'Alessandro A, Clendenen N, Hansen KC. Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots. J Biol Chem. 2019 05 31; 294(22):8773-8778.
    View in: PubMed
    Score: 0.004
  315. Francis RO, Mahajan S, Rapido F, La Carpia F, Soffing M, Divgi C, Yeh R, Mintz A, Leslie L, Agrest I, Karafin MS, Ginzburg Y, Shaz BH, Spitalnik SL, Schwartz J, Thomas T, Fu X, Amireault P, Buffet P, Zimring JC, D'Alessandro A, Hod EA. Reexamination of the chromium-51-labeled posttransfusion red blood cell recovery method. Transfusion. 2019 07; 59(7):2264-2275.
    View in: PubMed
    Score: 0.004
  316. Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J. Targeting Glutamine Metabolism and Redox State for Leukemia Therapy. Clin Cancer Res. 2019 07 01; 25(13):4079-4090.
    View in: PubMed
    Score: 0.004
  317. Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens BM, Jones CL, D'Alessandro A, Reisz JA, Zaberezhnyy V, Gasparetto M, Ho TC, Kelly KK, Myers JR, Ashton JM, Siegenthaler J, Kume T, Campbell EL, Pollyea DA, Becker MW, Jordan CT. The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells. Cell Rep. 2019 04 02; 27(1):238-254.e6.
    View in: PubMed
    Score: 0.004
  318. Freedman R, Hunter SK, Law AJ, Wagner BD, D'Alessandro A, Christians U, Noonan K, Wyrwa A, Hoffman MC. Higher Gestational Choline Levels in Maternal Infection Are Protective for Infant Brain Development. J Pediatr. 2019 05; 208:198-206.e2.
    View in: PubMed
    Score: 0.004
  319. Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J. Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC. Mol Cancer Res. 2019 06; 17(6):1351-1364.
    View in: PubMed
    Score: 0.004
  320. Moore HB, D'Alessandro A, Moore EE, Wither M, Lawson PJ, Huebner BR, Hansen K, Choudhury R, Nydam TL. Increase in post-reperfusion sensitivity to tissue plasminogen activator-mediated fibrinolysis during liver transplantation is associated with abnormal metabolic changes and increased blood product utilisation. Blood Transfus. 2019 07; 17(4):312-320.
    View in: PubMed
    Score: 0.004
  321. Fox BM, Gil HW, Kirkbride-Romeo L, Bagchi RA, Wennersten SA, Haefner KR, Skrypnyk NI, Brown CN, Soranno DE, Gist KM, Griffin BR, Jovanovich A, Reisz JA, Wither MJ, D'Alessandro A, Edelstein CL, Clendenen N, McKinsey TA, Altmann C, Faubel S. Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice. Kidney Int. 2019 03; 95(3):590-610.
    View in: PubMed
    Score: 0.004
  322. Lana A, Alexander K, Castagna A, D'Alessandro A, Morandini F, Pizzolo F, Zorzi F, Mulatero P, Zolla L, Olivieri O. Urinary Metabolic Signature of Primary Aldosteronism: Gender and Subtype-Specific Alterations. Proteomics Clin Appl. 2019 07; 13(4):e1800049.
    View in: PubMed
    Score: 0.004
  323. Rogers SC, Dosier LB, McMahon TJ, Zhu H, Timm D, Zhang H, Herbert J, Atallah J, Palmer GM, Cook A, Ernst M, Prakash J, Terng M, Towfighi P, Doctor R, Said A, Joens MS, Fitzpatrick JAJ, Hanna G, Lin X, Reisz JA, Nemkov T, D'Alessandro A, Doctor A. Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes. PLoS One. 2018; 13(12):e0209201.
    View in: PubMed
    Score: 0.004
  324. Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 2019 01 24; 176(3):564-580.e19.
    View in: PubMed
    Score: 0.004
  325. Sheridan RM, Fong N, D'Alessandro A, Bentley DL. Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5' Pause Release, Termination, and Transcription Elongation Rate. Mol Cell. 2019 01 03; 73(1):107-118.e4.
    View in: PubMed
    Score: 0.004
  326. Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D'Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbott D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT. Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia. Nat Med. 2018 12; 24(12):1859-1866.
    View in: PubMed
    Score: 0.004
  327. Jones CL, Stevens BM, D'Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Adane B, Ye H, Krug A, Reinhold D, Smith C, DeGregori J, Pollyea DA, Jordan CT. Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells. Cancer Cell. 2018 11 12; 34(5):724-740.e4.
    View in: PubMed
    Score: 0.004
  328. Karafin MS, Fu X, D'Alessandro A, Thomas T, Hod EA, Zimring JC, Field JJ, Francis RO. The clinical impact of glucose-6-phosphate dehydrogenase deficiency in patients with sickle cell disease. Curr Opin Hematol. 2018 11; 25(6):494-499.
    View in: PubMed
    Score: 0.004
  329. Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Young B, Krebs N, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE. The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nat Commun. 2018 10 26; 9(1):4462.
    View in: PubMed
    Score: 0.004
  330. Nemkov T, D'Alessandro A, Reisz JA. Metabolic underpinnings of leukemia pathology and treatment. Cancer Rep (Hoboken). 2019 04; 2(2):e1139.
    View in: PubMed
    Score: 0.004
  331. Rogers TJ, Christenson JL, Greene LI, O'Neill KI, Williams MM, Gordon MA, Nemkov T, D'Alessandro A, Degala GD, Shin J, Tan AC, Cittelly DM, Lambert JR, Richer JK. Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression. Mol Cancer Res. 2019 01; 17(1):30-41.
    View in: PubMed
    Score: 0.004
  332. Stevens BM, Khan N, D'Alessandro A, Nemkov T, Winters A, Jones CL, Zhang W, Pollyea DA, Jordan CT. Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes. Nat Commun. 2018 09 12; 9(1):3694.
    View in: PubMed
    Score: 0.004
  333. Greene LI, Bruno TC, Christenson JL, D'Alessandro A, Culp-Hill R, Torkko K, Borges VF, Slansky JE, Richer JK. A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma. Mol Cancer Res. 2019 01; 17(1):131-139.
    View in: PubMed
    Score: 0.004
  334. Zhang Y, Lee JH, Paull TT, Gehrke S, D'Alessandro A, Dou Q, Gladyshev VN, Schroeder EA, Steyl SK, Christian BE, Shadel GS. Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity. Sci Signal. 2018 07 10; 11(538).
    View in: PubMed
    Score: 0.004
  335. Haines NR, Manoharan N, Olson JL, D'Alessandro A, Reisz JA. Metabolomics Analysis of Human Vitreous in Diabetic Retinopathy and Rhegmatogenous Retinal Detachment. J Proteome Res. 2018 07 06; 17(7):2421-2427.
    View in: PubMed
    Score: 0.004
  336. Banerjee A, Silliman CC, Moore EE, Dzieciatkowska M, Kelher M, Sauaia A, Jones K, Chapman MP, Gonzalez E, Moore HB, D'Alessandro A, Peltz E, Huebner BE, Einerson P, Chandler J, Ghasabayan A, Hansen K. Systemic hyperfibrinolysis after trauma: a pilot study of targeted proteomic analysis of superposed mechanisms in patient plasma. J Trauma Acute Care Surg. 2018 06; 84(6):929-938.
    View in: PubMed
    Score: 0.004
  337. El Kasmi KC, Vue PM, Anderson AL, Devereaux MW, Ghosh S, Balasubramaniyan N, Fillon SA, Dahrenmoeller C, Allawzi A, Woods C, McKenna S, Wright CJ, Johnson L, D'Alessandro A, Reisz JA, Nozik-Grayck E, Suchy FJ, Sokol RJ. Macrophage-derived IL-1ß/NF-?B signaling mediates parenteral nutrition-associated cholestasis. Nat Commun. 2018 04 11; 9(1):1393.
    View in: PubMed
    Score: 0.004
  338. Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem. 2018 05 04; 293(18):6659-6671.
    View in: PubMed
    Score: 0.004
  339. Perreault L, Newsom SA, Strauss A, Kerege A, Kahn DE, Harrison KA, Snell-Bergeon JK, Nemkov T, D'Alessandro A, Jackman MR, MacLean PS, Bergman BC. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle. JCI Insight. 2018 02 08; 3(3).
    View in: PubMed
    Score: 0.004
  340. Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA. OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1530-E1539.
    View in: PubMed
    Score: 0.004
  341. Mitra S, Schiller D, Anderson C, Gamboni F, D'Alessandro A, Kelher M, Silliman CC, Banerjee A, Jones KL. Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia. PLoS One. 2017; 12(12):e0189536.
    View in: PubMed
    Score: 0.004
  342. Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn SA, Hess JR, Klein H, Acker JP, Spinella PC, D'Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon TJ, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM. Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016. Transfusion. 2018 01; 58(1):255-266.
    View in: PubMed
    Score: 0.004
  343. Sun K, D'Alessandro A, Ahmed MH, Zhang Y, Song A, Ko TP, Nemkov T, Reisz JA, Wu H, Adebiyi M, Peng Z, Gong J, Liu H, Huang A, Wen YE, Wen AQ, Berka V, Bogdanov MV, Abdulmalik O, Han L, Tsai AL, Idowu M, Juneja HS, Kellems RE, Dowhan W, Hansen KC, Safo MK, Xia Y. Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease. Sci Rep. 2017 11 10; 7(1):15281.
    View in: PubMed
    Score: 0.004
  344. Barrett AS, Wither MJ, Hill RC, Dzieciatkowska M, D'Alessandro A, Reisz JA, Hansen KC. Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization. J Proteome Res. 2017 11 03; 16(11):4177-4184.
    View in: PubMed
    Score: 0.004
  345. Caruso P, Dunmore BJ, Schlosser K, Schoors S, Dos Santos C, Perez-Iratxeta C, Lavoie JR, Zhang H, Long L, Flockton AR, Frid MG, Upton PD, D'Alessandro A, Hadinnapola C, Kiskin FN, Taha M, Hurst LA, Ormiston ML, Hata A, Stenmark KR, Carmeliet P, Stewart DJ, Morrell NW. Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2. Circulation. 2017 Dec 19; 136(25):2451-2467.
    View in: PubMed
    Score: 0.003
  346. Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton A, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Je?ek P, Morrell NW, Hu CJ, Stenmark KR. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis. Circulation. 2017 Dec 19; 136(25):2468-2485.
    View in: PubMed
    Score: 0.003
  347. Gregory MA, Nemkov T, Reisz JA, Zaberezhnyy V, Hansen KC, D'Alessandro A, DeGregori J. Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia. Exp Hematol. 2018 02; 58:52-58.
    View in: PubMed
    Score: 0.003
  348. Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T. An autonomous metabolic role for Spen. PLoS Genet. 2017 Jun; 13(6):e1006859.
    View in: PubMed
    Score: 0.003
  349. Sun K, Liu H, Song A, Manalo JM, D'Alessandro A, Hansen KC, Kellems RE, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Erythrocyte purinergic signaling components underlie hypoxia adaptation. J Appl Physiol (1985). 2017 Oct 01; 123(4):951-956.
    View in: PubMed
    Score: 0.003
  350. Sun K, D'alessandro A, Xia Y. Purinergic control of red blood cell metabolism: novel strategies to improve red cell storage quality. Blood Transfus. 2017 Oct; 15(6):535-542.
    View in: PubMed
    Score: 0.003
  351. Clendenen N, Tollefson A, Dzieciatkowska M, Cambiaghi A, Ferrario M, Kroehl M, Banerjee A, D'Alessandro A, Hansen KC, Weitzel N. Correlation of pre-operative plasma protein concentrations in cardiac surgery patients with bleeding outcomes using a targeted quantitative proteomics approach. Proteomics Clin Appl. 2017 07; 11(7-8).
    View in: PubMed
    Score: 0.003
  352. Yoshida T, Blair A, D'alessandro A, Nemkov T, Dioguardi M, Silliman CC, Dunham A. Enhancing uniformity and overall quality of red cell concentrate with anaerobic storage. Blood Transfus. 2017 Mar; 15(2):172-181.
    View in: PubMed
    Score: 0.003
  353. Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2313-2318.
    View in: PubMed
    Score: 0.003
  354. Song A, Zhang Y, Han L, Yegutkin GG, Liu H, Sun K, D'Alessandro A, Li J, Karmouty-Quintana H, Iriyama T, Weng T, Zhao S, Wang W, Wu H, Nemkov T, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Hansen KC, Zhang H, Bogdanov M, Dowhan W, Jin J, Kellems RE, Eltzschig HK, Blackburn M, Roach RC, Xia Y. Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017 02 07; 8:14108.
    View in: PubMed
    Score: 0.003
  355. Kendrick AA, Schafer J, Dzieciatkowska M, Nemkov T, D'Alessandro A, Neelakantan D, Ford HL, Pearson CG, Weekes CD, Hansen KC, Eisenmesser EZ. CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. Oncotarget. 2017 Jan 24; 8(4):6742-6762.
    View in: PubMed
    Score: 0.003
  356. Plecitá-Hlavatá L, D'alessandro A, El Kasmi K, Li M, Zhang H, Je?ek P, Stenmark KR. Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension. Adv Exp Med Biol. 2017; 967:241-260.
    View in: PubMed
    Score: 0.003
  357. Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P. The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis. Cancer Discov. 2017 02; 7(2):177-187.
    View in: PubMed
    Score: 0.003
  358. Kalker AJ, Pirsch JD, Heisey D, Sollinger HW, Belzer FO, Knechtle SJ, D'Alessandro AM. Foot problems in the diabetic transplant recipient. Clin Transplant. 1996 Dec; 10(6 Pt 1):503-10.
    View in: PubMed
    Score: 0.003
  359. Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):E6669-E6678.
    View in: PubMed
    Score: 0.003
  360. Gamboni F, Anderson C, Mitra S, Reisz JA, Nemkov T, Dzieciatkowska M, Jones KL, Hansen KC, D'Alessandro A, Banerjee A. Hypertonic Saline Primes Activation of the p53-p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines. J Proteome Res. 2016 10 07; 15(10):3813-3826.
    View in: PubMed
    Score: 0.003
  361. Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells. J Biol Chem. 2016 Oct 14; 291(42):21984-22000.
    View in: PubMed
    Score: 0.003
  362. Scalea JR, Redfield RR, Arpali E, Leverson GE, Bennett RJ, Anderson ME, Kaufman DB, Fernandez LA, D'Alessandro AM, Foley DP, Mezrich JD. Does DCD Donor Time-to-Death Affect Recipient Outcomes? Implications of Time-to-Death at a High-Volume Center in the United States. Am J Transplant. 2017 01; 17(1):191-200.
    View in: PubMed
    Score: 0.003
  363. Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldovan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Je?ek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR. Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1. Circulation. 2016 10 11; 134(15):1105-1121.
    View in: PubMed
    Score: 0.003
  364. Paglia G, D'Alessandro A, Rolfsson Ó, Sigurjónsson ÓE, Bordbar A, Palsson S, Nemkov T, Hansen KC, Gudmundsson S, Palsson BO. Biomarkers defining the metabolic age of red blood cells during cold storage. Blood. 2016 09 29; 128(13):e43-50.
    View in: PubMed
    Score: 0.003
  365. Liu H, Zhang Y, Wu H, D'Alessandro A, Yegutkin GG, Song A, Sun K, Li J, Cheng NY, Huang A, Edward Wen Y, Weng TT, Luo F, Nemkov T, Sun H, Kellems RE, Karmouty-Quintana H, Hansen KC, Zhao B, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Eltzschig HK, Blackburn MR, Roach RC, Xia Y. Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia. Circulation. 2016 Aug 02; 134(5):405-21.
    View in: PubMed
    Score: 0.003
  366. Sun K, Zhang Y, D'Alessandro A, Nemkov T, Song A, Wu H, Liu H, Adebiyi M, Huang A, Wen YE, Bogdanov MV, Vila A, O'Brien J, Kellems RE, Dowhan W, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Safo M, Hansen KC, Roach RC, Xia Y. Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia. Nat Commun. 2016 07 15; 7:12086.
    View in: PubMed
    Score: 0.003
  367. Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'Alessandro A, El Kasmi KC, Je?ek P, Stenmark KR. Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2016 07; 55(1):47-57.
    View in: PubMed
    Score: 0.003
  368. Tzounakas VL, Kriebardis AG, Georgatzakou HT, Foudoulaki-Paparizos LE, Dzieciatkowska M, Wither MJ, Nemkov T, Hansen KC, Papassideri IS, D'Alessandro A, Antonelou MH. Glucose 6-phosphate dehydrogenase deficient subjects may be better "storers" than donors of red blood cells. Free Radic Biol Med. 2016 07; 96:152-65.
    View in: PubMed
    Score: 0.003
  369. Newsom SA, Brozinick JT, Kiseljak-Vassiliades K, Strauss AN, Bacon SD, Kerege AA, Bui HH, Sanders P, Siddall P, Wei T, Thomas M, Kuo MS, Nemkov T, D'Alessandro A, Hansen KC, Perreault L, Bergman BC. Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans. J Appl Physiol (1985). 2016 Jun 01; 120(11):1355-63.
    View in: PubMed
    Score: 0.003
  370. Goodman SR, Pace BS, Hansen KC, D'alessandro A, Xia Y, Daescu O, Glatt SJ. Minireview: Multiomic candidate biomarkers for clinical manifestations of sickle cell severity: Early steps to precision medicine. Exp Biol Med (Maywood). 2016 Apr; 241(7):772-81.
    View in: PubMed
    Score: 0.003
  371. Dumont LJ, D'Alessandro A, Szczepiorkowski ZM, Yoshida T. CO2 -dependent metabolic modulation in red blood cells stored under anaerobic conditions. Transfusion. 2016 Feb; 56(2):392-403.
    View in: PubMed
    Score: 0.003
  372. Wither M, Dzieciatkowska M, Nemkov T, Strop P, D'Alessandro A, Hansen KC. Hemoglobin oxidation at functional amino acid residues during routine storage of red blood cells. Transfusion. 2016 Feb; 56(2):421-6.
    View in: PubMed
    Score: 0.003
  373. Moore HB, Moore EE, Chapman MP, Gonzalez E, Slaughter AL, Morton AP, D'Alessandro A, Hansen KC, Sauaia A, Banerjee A, Silliman CC. Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients. J Thromb Haemost. 2015 Oct; 13(10):1878-87.
    View in: PubMed
    Score: 0.003
  374. D'Amato NC, Rogers TJ, Gordon MA, Greene LI, Cochrane DR, Spoelstra NS, Nemkov TG, D'Alessandro A, Hansen KC, Richer JK. A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer. Cancer Res. 2015 Nov 01; 75(21):4651-64.
    View in: PubMed
    Score: 0.003
  375. D'Alessandro AM, Sollinger HW, Knechtle SJ, Kalayoglu M, Kisken WA, Uehling DT, Moon TD, Messing EM, Bruskewitz RC, Pirsch JD, et al. Living related and unrelated donors for kidney transplantation. A 28-year experience. Ann Surg. 1995 Sep; 222(3):353-62; discussion 362-4.
    View in: PubMed
    Score: 0.003
  376. Peltz ED, D'Alessandro A, Moore EE, Chin T, Silliman CC, Sauaia A, Hansen KC, Banerjee A. Pathologic metabolism: an exploratory study of the plasma metabolome of critical injury. J Trauma Acute Care Surg. 2015 Apr; 78(4):742-51.
    View in: PubMed
    Score: 0.003
  377. Hansen KC, D'Alessandro A, Clement CC, Santambrogio L. Lymph formation, composition and circulation: a proteomics perspective. Int Immunol. 2015 May; 27(5):219-27.
    View in: PubMed
    Score: 0.003
  378. Dzieciatkowska M, D'Alessandro A, Hill RC, Hansen KC. Plasma QconCATs reveal a gender-specific proteomic signature in apheresis platelet plasma supernatants. J Proteomics. 2015 Apr 29; 120:1-6.
    View in: PubMed
    Score: 0.003
  379. D'Alessandro AM, Hoffmann RM, Knechtle SJ, Eckhoff DE, Love RB, Kalayoglu M, Sollinger HW, Belzer FO. Controlled non-heart-beating donors: a potential source of extrarenal organs. Transplant Proc. 1995 Feb; 27(1):707-9.
    View in: PubMed
    Score: 0.003
  380. Wiener G, Moore HB, Moore EE, Gonzalez E, Diamond S, Zhu S, D'Alessandro A, Banerjee A. Shock releases bile acid inducing platelet inhibition and fibrinolysis. J Surg Res. 2015 May 15; 195(2):390-5.
    View in: PubMed
    Score: 0.003
  381. Cilli D, Mirasole C, Pennisi R, Pallotta V, D'Alessandro A, Antoccia A, Zolla L, Ascenzi P, di Masi A. Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation. PLoS One. 2014; 9(12):e114651.
    View in: PubMed
    Score: 0.003
  382. Dzieciatkowska M, D'Alessandro A, Moore EE, Wohlauer M, Banerjee A, Silliman CC, Hansen KC. Lymph is not a plasma ultrafiltrate: a proteomic analysis of injured patients. Shock. 2014 Dec; 42(6):485-498.
    View in: PubMed
    Score: 0.003
  383. D'Alessandro AM, Southard JH, Love RB, Belzer FO. Organ preservation. Surg Clin North Am. 1994 Oct; 74(5):1083-95.
    View in: PubMed
    Score: 0.003
  384. Zolla L, D'alessandro A, Rinalducci S, D'amici GM, Pupella S, Vaglio S, Grazzini G. Classic and alternative red blood cell storage strategies: seven years of "-omics" investigations. Blood Transfus. 2015 Jan; 13(1):21-31.
    View in: PubMed
    Score: 0.003
  385. Dzieciatkowska M, D'Alessandro A, Burke TA, Kelher MR, Moore EE, Banerjee A, Silliman CC, West BF, Hansen KC. Proteomics of apheresis platelet supernatants during routine storage: Gender-related differences. J Proteomics. 2015 Jan 01; 112:190-209.
    View in: PubMed
    Score: 0.003
  386. Pallotta V, Gevi F, D'alessandro A, Zolla L. Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions: a metabolomics overview. Blood Transfus. 2014 Jul; 12(3):376-87.
    View in: PubMed
    Score: 0.003
  387. Pallotta V, Naro F, Gevi F, D'Alessandro A, Zolla L. Supplementation of anti-oxidants in leucofiltered erythrocyte concentrates: assessment of morphological changes through scanning electron microscopy. Blood Transfus. 2014 Jul; 12(3):421-4.
    View in: PubMed
    Score: 0.003
  388. Cialfi S, Palermo R, Manca S, De Blasio C, Vargas Romero P, Checquolo S, Bellavia D, Uccelletti D, Saliola M, D'Alessandro A, Zolla L, Gulino A, Screpanti I, Talora C. Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis. Cell Cycle. 2014; 13(13):2046-55.
    View in: PubMed
    Score: 0.003
  389. Prudent M, D'Alessandro A, Cazenave JP, Devine DV, Gachet C, Greinacher A, Lion N, Schubert P, Steil L, Thiele T, Tissot JD, Völker U, Zolla L. Proteome changes in platelets after pathogen inactivation--an interlaboratory consensus. Transfus Med Rev. 2014 Apr; 28(2):72-83.
    View in: PubMed
    Score: 0.003
  390. Olivieri O, Cecconi D, Castagna A, Chiecchi L, Guarini P, Gunasekaran M, Morandini F, Brazzarola P, Zolla L, D'Alessandro A, Veglio F, Mulatero P, Pizzolo F. Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma. Mol Biosyst. 2014 Jun; 10(6):1281-9.
    View in: PubMed
    Score: 0.003
  391. Pallotta V, D'Alessandro A, Rinalducci S, Zolla L. Native protein complexes in the cytoplasm of red blood cells. J Proteome Res. 2013 Jul 05; 12(7):3529-46.
    View in: PubMed
    Score: 0.003
  392. Longo V, D'alessandro A, Zolla L. Deoxygenation of leucofiltered erythrocyte concentrates preserves proteome stability during storage in the blood bank. Blood Transfus. 2014 Oct; 12(4):599-604.
    View in: PubMed
    Score: 0.003
  393. Zolla L, D'Alessandro A, Parguiña AF, García Á. In reply to: "Further comments on platelet proteomics in Transfusion Medicine". Blood Transfus. 2014 Jan; 12 Suppl 1:s246.
    View in: PubMed
    Score: 0.003
  394. Marrocco C, D'Alessandro A, Girelli G, Zolla L. Proteomic analysis of platelets treated with gamma irradiation versus a commercial photochemical pathogen reduction technology. Transfusion. 2013 Aug; 53(8):1808-20.
    View in: PubMed
    Score: 0.003
  395. D'Amici GM, Mirasole C, D'Alessandro A, Yoshida T, Dumont LJ, Zolla L. Red blood cell storage in SAGM and AS3: a comparison through the membrane two-dimensional electrophoresis proteome. Blood Transfus. 2012 May; 10 Suppl 2:s46-54.
    View in: PubMed
    Score: 0.002
  396. Marrocco C, Pallotta V, D'alessandro A, Alves G, Zolla L. Red blood cell populations and membrane levels of peroxiredoxin 2 as candidate biomarkers to reveal blood doping. Blood Transfus. 2012 May; 10 Suppl 2:s71-7.
    View in: PubMed
    Score: 0.002
  397. Blasi B, D'Amici GM, D'Alessandro A, Zolla L. Native analysis of plasma-derived clotting factor VIII concentrates: "sponge effect" and contaminants. Electrophoresis. 2012 Apr; 33(8):1292-8.
    View in: PubMed
    Score: 0.002
  398. Gevi F, D'Alessandro A, Rinalducci S, Zolla L. Alterations of red blood cell metabolome during cold liquid storage of erythrocyte concentrates in CPD-SAGM. J Proteomics. 2012 Dec 05; 76 Spec No.:168-80.
    View in: PubMed
    Score: 0.002
  399. Pallotta V, D'Amici GM, D'Alessandro A, Rossetti R, Zolla L. Red blood cell processing for cryopreservation: from fresh blood to deglycerolization. Blood Cells Mol Dis. 2012 Apr 15; 48(4):226-32.
    View in: PubMed
    Score: 0.002
  400. Blasi B, D'Alessandro A, Ramundo N, Zolla L. Red blood cell storage and cell morphology. Transfus Med. 2012 Apr; 22(2):90-6.
    View in: PubMed
    Score: 0.002
  401. D'Amici GM, Blasi B, D'Alessandro A, Vaglio S, Zolla L. Plasma-derived clotting factor VIII: heterogeneity evaluation in the quest for potential inhibitory-antibody stimulating factors. Electrophoresis. 2011 Nov; 32(21):2941-50.
    View in: PubMed
    Score: 0.002
  402. Musat AI, Agni RM, Wai PY, Pirsch JD, Lorentzen DF, Powell A, Leverson GE, Bellingham JM, Fernandez LA, Foley DP, Mezrich JD, D'Alessandro AM, Lucey MR. The significance of donor-specific HLA antibodies in rejection and ductopenia development in ABO compatible liver transplantation. Am J Transplant. 2011 Mar; 11(3):500-10.
    View in: PubMed
    Score: 0.002
  403. Egidi MG, D'Alessandro A, Mandarello G, Zolla L. Troubleshooting in platelet storage temperature and new perspectives through proteomics. Blood Transfus. 2010 Jun; 8 Suppl 3:s73-81.
    View in: PubMed
    Score: 0.002
  404. Liumbruno G, D'Alessandro A, Grazzini G, Zolla L. How has proteomics informed transfusion biology so far? Crit Rev Oncol Hematol. 2010 Dec; 76(3):153-72.
    View in: PubMed
    Score: 0.002
  405. Liumbruno GM, D'Alessandro A, Rea F, Piccinini V, Catalano L, Calizzani G, Pupella S, Grazzini G. The role of antenatal immunoprophylaxis in the prevention of maternal-foetal anti-Rh(D) alloimmunisation. Blood Transfus. 2010 Jan; 8(1):8-16.
    View in: PubMed
    Score: 0.002
  406. Liumbruno G, D'Alessandro A, Grazzini G, Zolla L. Blood-related proteomics. J Proteomics. 2010 Jan 03; 73(3):483-507.
    View in: PubMed
    Score: 0.002
  407. Yagci G, Fernandez LA, Knechtle SJ, D'Alessandro AM, Chin LT, Musat AI, Lucey MR, Said A, Pirsch JD, Leverson G, Kalayoglu M. The impact of donor variables on the outcome of orthotopic liver transplantation for hepatitis C. Transplant Proc. 2008 Jan-Feb; 40(1):219-23.
    View in: PubMed
    Score: 0.002
  408. Sollinger HW, Becker YT, Burlingham W, D'Alessandro AM, Fernandez LA, Hullett D, Knechtle SJ, Odorico JS, O'Loughlin S, Pirsch JD, Rieselbach RE, Sundberg A, Voss B. The history of the University of Wisconsin transplant program. Clin Transpl. 2007; 271-87.
    View in: PubMed
    Score: 0.002
  409. Bernat JL, D'Alessandro AM, Port FK, Bleck TP, Heard SO, Medina J, Rosenbaum SH, Devita MA, Gaston RS, Merion RM, Barr ML, Marks WH, Nathan H, O'connor K, Rudow DL, Leichtman AB, Schwab P, Ascher NL, Metzger RA, Mc Bride V, Graham W, Wagner D, Warren J, Delmonico FL. Report of a National Conference on Donation after cardiac death. Am J Transplant. 2006 Feb; 6(2):281-91.
    View in: PubMed
    Score: 0.002
  410. Boccellino M, Giuberti G, Quagliuolo L, Marra M, D'Alessandro AM, Fujita H, Giovane A, Abbruzzese A, Caraglia M. Apoptosis induced by interferon-alpha and antagonized by EGF is regulated by caspase-3-mediated cleavage of gelsolin in human epidermoid cancer cells. J Cell Physiol. 2004 Oct; 201(1):71-83.
    View in: PubMed
    Score: 0.001
  411. Caraglia M, Marra M, Giuberti G, D'Alessandro AM, Baldi A, Tassone P, Venuta S, Tagliaferri P, Abbruzzese A. The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells. J Biochem. 2003 Jun; 133(6):757-65.
    View in: PubMed
    Score: 0.001
  412. Del Prete S, Caraglia M, Russo D, Vitale G, Giuberti G, Marra M, D'Alessandro AM, Lupoli G, Addeo R, Facchini G, Rossiello R, Abbruzzese A, Capasso E. Percutaneous ethanol injection efficacy in the treatment of large symptomatic thyroid cystic nodules: ten-year follow-up of a large series. Thyroid. 2002 Sep; 12(9):815-21.
    View in: PubMed
    Score: 0.001
  413. Cho CS, Knechtle SJ, Heisey DM, Hermina M, Armbrust M, D'Alessandro AM, Musat AI, Kalayoglu M. Analysis of tumor characteristics and survival in liver transplant recipients with incidentally diagnosed hepatocellular carcinoma. J Gastrointest Surg. 2001 Nov-Dec; 5(6):594-601; discussion 601-2.
    View in: PubMed
    Score: 0.001
  414. Shames BD, D'Alessandro AM, Pirsch JD, Knechtle SJ, Odorico JS, Becker YT, Kalayoglu M, Chin LT, Sollinger HW. Living-unrelated renal transplantation at the University of Wisconsin. Clin Transpl. 2001; 149-56.
    View in: PubMed
    Score: 0.001
  415. Rayhill SC, D'Alessandro AM, Odorico JS, Knechtle SJ, Pirsch JD, Heisey DM, Kirk AD, Van der Werf W, Sollinger HW. Simultaneous pancreas-kidney transplantation and living related donor renal transplantation in patients with diabetes: is there a difference in survival? Ann Surg. 2000 Mar; 231(3):417-23.
    View in: PubMed
    Score: 0.001
  416. Van der Werf WJ, Odorico J, D'Alessandro AM, Knechtle S, Becker Y, Collins B, Pirsch J, Hoffman R, Sollinger HW. Utilization of pediatric donors for pancreas transplantation. Transplant Proc. 1999 Feb-Mar; 31(1-2):610-1.
    View in: PubMed
    Score: 0.001
  417. Odorico JS, Leverson GE, Becker YT, Pirsch JD, Knechtle SJ, D'Alessandro AM, Sollinger HW. Pancreas transplantation at the University of Wisconsin. Clin Transpl. 1999; 199-210.
    View in: PubMed
    Score: 0.001
  418. Sollinger HW, Odorico JS, Knechtle SJ, D'Alessandro AM, Kalayoglu M, Pirsch JD. Experience with 500 simultaneous pancreas-kidney transplants. Ann Surg. 1998 Sep; 228(3):284-96.
    View in: PubMed
    Score: 0.001
  419. Van der Werf WJ, D'Alessandro AM, Hoffmann RM, Knechtle SJ. Procurement, preservation, and transport of cadaver kidneys. Surg Clin North Am. 1998 Feb; 78(1):41-54.
    View in: PubMed
    Score: 0.001
  420. Sher LS, Cosenza CA, Michel J, Makowka L, Miller CM, Schwartz ME, Busuttil R, McDiarmid S, Burdick JF, Klein AS, Esquivel C, Klintmalm G, Levy M, Roberts JP, Lake JR, Kalayoglu M, D'Alessandro AM, Gordon RD, Stieber AC, Shaw BW, Thistlethwaite JR, Whittington P, Wiesner RH, Porayko M, Cosimi AB, et al. Efficacy of tacrolimus as rescue therapy for chronic rejection in orthotopic liver transplantation: a report of the U.S. Multicenter Liver Study Group. Transplantation. 1997 Jul 27; 64(2):258-63.
    View in: PubMed
    Score: 0.001
  421. Knechtle SJ, Kalayoglu M, D'Alessandro AM, Rikkers LF. Proceed with caution: liver transplantation for metastatic neuroendocrine tumors. Ann Surg. 1997 Apr; 225(4):345-6.
    View in: PubMed
    Score: 0.001
  422. Lochhead KM, Pirsch JD, D'Alessandro AM, Knechtle SJ, Kalayoglu M, Sollinger HW, Belzer FO. Risk factors for renal allograft loss in patients with systemic lupus erythematosus. Kidney Int. 1996 Feb; 49(2):512-7.
    View in: PubMed
    Score: 0.001
  423. Knechtle SJ, D'Alessandro AM, Harms BA, Pirsch JD, Belzer FO, Kalayoglu M. Relationships between sclerosing cholangitis, inflammatory bowel disease, and cancer in patients undergoing liver transplantation. Surgery. 1995 Oct; 118(4):615-9; discussion 619-20.
    View in: PubMed
    Score: 0.001
  424. Knechtle SJ, Kalayoglu M, D'Alessandro AM, Pirsch JD, Armbrust MJ, Sproat IA, Wojtowycz MM, McDermott JC, Crummy AB, Belzer FO. Portal hypertension: surgical management in the 1990s. Surgery. 1994 Oct; 116(4):687-93; discussion 693-5.
    View in: PubMed
    Score: 0.001
  425. Ploeg RJ, D'Alessandro AM, Groshek M, Gange SJ, Knechtle SJ, Stegall MD, Eckhoff DE, Pirsch JD, Sollinger HW, Belzer FO. Clinical experience with human anodal trypsinogen (HAT) for detection of pancreatic allograft rejection. Transpl Int. 1994; 7 Suppl 1:S426-31.
    View in: PubMed
    Score: 0.001
  426. Ploeg RJ, D'Alessandro AM, Hoffmann RM, Eckhoff D, Isaacs R, Knechtle SJ, Pirsch JD, Stegall MD, Kalayoglu M, Belzer FO. Impact of donor factors and preservation on function and survival after liver transplantation. Transplant Proc. 1993 Dec; 25(6):3031-3.
    View in: PubMed
    Score: 0.001
  427. Sollinger HW, Messing EM, Eckhoff DE, Pirsch JD, D'Alessandro AM, Kalayoglu M, Knechtle SJ, Hickey D, Belzer FO. Urological complications in 210 consecutive simultaneous pancreas-kidney transplants with bladder drainage. Ann Surg. 1993 Oct; 218(4):561-8; discussion 568-70.
    View in: PubMed
    Score: 0.001
  428. Knechtle SJ, Fleming MF, Barry KL, Steen D, Pirsch JD, D'Alessandro AM, Kalayoglu M, Belzer FO. Liver transplantation in alcoholics: assessment of psychological health and work activity. Transplant Proc. 1993 Apr; 25(2):1916-8.
    View in: PubMed
    Score: 0.001
  429. Belzer FO, D'Alessandro AM, Hoffmann RM, Knechtle SJ, Reed A, Pirsch JD, Kalayoglu M, Sollinger HW. The use of UW solution in clinical transplantation. A 4-year experience. Ann Surg. 1992 Jun; 215(6):579-83; discussion 584-5.
    View in: PubMed
    Score: 0.001
  430. Sollinger HW, Knechtle SJ, Reed A, D'Alessandro AM, Kalayoglu M, Belzer FO, Pirsch J. Experience with 100 consecutive simultaneous kidney-pancreas transplants with bladder drainage. Ann Surg. 1991 Dec; 214(6):703-11.
    View in: PubMed
    Score: 0.001
  431. Perilli V, Sollazzi L, Valenti M, D'Alessandro AM, Lo Monaco M, Pelosi G. [Use of atracurium in patients with muscular diseases. 2 cases of distal and mitochondrial myopathy]. Minerva Anestesiol. 1991 Jul-Aug; 57(7-8):441-4.
    View in: PubMed
    Score: 0.001
  432. Pirsch JD, Stratta RJ, Armbrust MJ, D'Alessandro AM, Sollinger HW, Kalayoglu M, Belzer FO. Cadaveric renal transplantation with cyclosporine in patients more than 60 years of age. Transplantation. 1989 Feb; 47(2):259-61.
    View in: PubMed
    Score: 0.000
  433. Sollinger HW, Stratta RJ, D'Alessandro AM, Kalayoglu M, Pirsch JD, Belzer FO. Experience with simultaneous pancreas-kidney transplantation. Ann Surg. 1988 Oct; 208(4):475-83.
    View in: PubMed
    Score: 0.000
  434. Kalayoglu M, Sollinger HW, Stratta RJ, D'Alessandro AM, Hoffmann RM, Pirsch JD, Belzer FO. Extended preservation of the liver for clinical transplantation. Lancet. 1988 Mar 19; 1(8586):617-9.
    View in: PubMed
    Score: 0.000
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)