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Connection

Andrea Bonetto to Cachexia

This is a "connection" page, showing publications Andrea Bonetto has written about Cachexia.

 
Connection Strength
 
 
 
13.101
 
  1. Livingston PD, Labbate Bonaldo AL, Jamnick NA, Weinzierl NM, Gammon CJ, Callaway CS, Lee S, Gao B, Goodspeed A, Carvalho RF, Young CD, Orlicky DJ, Adams DJ, Novinger LJ, Bonetto A. B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer. Am J Physiol Cell Physiol. 2025 08 01; 329(2):C646-C658.
    View in: PubMed
    Score: 0.839
  2. Novinger LJ, Weinzierl NM, Bonetto A. Diversity in chemotherapy-induced cachexia. Am J Physiol Cell Physiol. 2025 01 01; 328(1):C139-C147.
    View in: PubMed
    Score: 0.803
  3. Balanta-Melo J, Jones AJ, Novinger LJ, Moore MG, Bonetto A. Masseter muscle thickness is predictive of cancer cachexia in patients with head and neck cancer. Head Neck. 2024 11; 46(11):2678-2686.
    View in: PubMed
    Score: 0.770
  4. Runco DV, Zimmers TA, Bonetto A. The urgent need to improve childhood cancer cachexia. Trends Cancer. 2022 12; 8(12):976-979.
    View in: PubMed
    Score: 0.683
  5. Huot JR, Pin F, Chatterjee R, Bonetto A. PGC1a overexpression preserves muscle mass and function in cisplatin-induced cachexia. J Cachexia Sarcopenia Muscle. 2022 10; 13(5):2480-2491.
    View in: PubMed
    Score: 0.682
  6. Pin F, Bonewald LF, Bonetto A. Role of myokines and osteokines in cancer cachexia. Exp Biol Med (Maywood). 2021 10; 246(19):2118-2127.
    View in: PubMed
    Score: 0.625
  7. Hulmi JJ, Nissinen TA, Penna F, Bonetto A. Targeting the Activin Receptor Signaling to Counteract the Multi-Systemic Complications of Cancer and Its Treatments. Cells. 2021 02 28; 10(3).
    View in: PubMed
    Score: 0.619
  8. Huot JR, Pin F, Essex AL, Bonetto A. MC38 Tumors Induce Musculoskeletal Defects in Colorectal Cancer. Int J Mol Sci. 2021 Feb 02; 22(3).
    View in: PubMed
    Score: 0.616
  9. Huot JR, Pin F, Narasimhan A, Novinger LJ, Keith AS, Zimmers TA, Willis MS, Bonetto A. ACVR2B antagonism as a countermeasure to multi-organ perturbations in metastatic colorectal cancer cachexia. J Cachexia Sarcopenia Muscle. 2020 12; 11(6):1779-1798.
    View in: PubMed
    Score: 0.607
  10. Huot JR, Novinger LJ, Pin F, Narasimhan A, Zimmers TA, O'Connell TM, Bonetto A. Formation of colorectal liver metastases induces musculoskeletal and metabolic abnormalities consistent with exacerbated cachexia. JCI Insight. 2020 05 07; 5(9).
    View in: PubMed
    Score: 0.585
  11. Huot JR, Novinger LJ, Pin F, Bonetto A. HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia. Dis Model Mech. 2020 01 24; 13(1).
    View in: PubMed
    Score: 0.573
  12. Pin F, Novinger LJ, Huot JR, Harris RA, Couch ME, O'Connell TM, Bonetto A. PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia. FASEB J. 2019 06; 33(6):7778-7790.
    View in: PubMed
    Score: 0.541
  13. Pin F, Barreto R, Kitase Y, Mitra S, Erne CE, Novinger LJ, Zimmers TA, Couch ME, Bonewald LF, Bonetto A. Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia. J Cachexia Sarcopenia Muscle. 2018 08; 9(4):685-700.
    View in: PubMed
    Score: 0.516
  14. Bonetto A, Rupert JE, Barreto R, Zimmers TA. The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia. J Vis Exp. 2016 11 30; (117).
    View in: PubMed
    Score: 0.461
  15. Barreto R, Waning DL, Gao H, Liu Y, Zimmers TA, Bonetto A. Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. Oncotarget. 2016 Jul 12; 7(28):43442-43460.
    View in: PubMed
    Score: 0.449
  16. Zimmers TA, Fishel ML, Bonetto A. STAT3 in the systemic inflammation of cancer cachexia. Semin Cell Dev Biol. 2016 06; 54:28-41.
    View in: PubMed
    Score: 0.436
  17. Bonetto A, Aydogdu T, Jin X, Zhang Z, Zhan R, Puzis L, Koniaris LG, Zimmers TA. JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia. Am J Physiol Endocrinol Metab. 2012 Aug 01; 303(3):E410-21.
    View in: PubMed
    Score: 0.338
  18. Bonetto A, Aydogdu T, Kunzevitzky N, Guttridge DC, Khuri S, Koniaris LG, Zimmers TA. STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia. PLoS One. 2011; 6(7):e22538.
    View in: PubMed
    Score: 0.318
  19. Bonetto A, Penna F, Minero VG, Reffo P, Bonelli G, Baccino FM, Costelli P. Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. Curr Cancer Drug Targets. 2009 Aug; 9(5):608-16.
    View in: PubMed
    Score: 0.277
  20. Ehimiaghe E, Nicklawsky A, Wang S, Torkko KC, Mastryoannis SA, Bonetto A, Novinger LJ. Prevalence of ovarian cancer cachexia in patients undergoing cytoreductive surgery at the University of Colorado between 2014-2024. J Ovarian Res. 2026 Apr 11; 19(1).
    View in: PubMed
    Score: 0.220
  21. Counts BR, Bonetto A, Chan HL, Au ED, Jiang Y, Couch ME, Guttridge DC, Ostrowski MC, Koniaris LG, Zimmers TA. High-fat diet and obesity each increase tumor cell proliferation and muscle wasting in experimental cancer cachexia. Am J Physiol Cell Physiol. 2026 Apr 01; 330(4):C727-C740.
    View in: PubMed
    Score: 0.218
  22. Thibaut MM, Roumain M, Piron E, Gillard J, Loriot A, Neyrinck AM, Rodriguez J, Massart I, Thissen JP, Huot JR, Pin F, Bonetto A, Delzenne NM, Muccioli GG, Bindels LB. The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia. Gut Microbes. 2025 Dec; 17(1):2449586.
    View in: PubMed
    Score: 0.202
  23. Jones AJ, Novinger LJ, Bonetto A, Davis KP, Giuliano MM, Mantravadi AV, Sim MW, Moore MG, Yesensky JA. Histopathologic Features of Mucosal Head and Neck Cancer Cachexia. Int J Surg Oncol. 2024; 2024:5339292.
    View in: PubMed
    Score: 0.195
  24. Callaway CS, Mouchantat LM, Bitler BG, Bonetto A. Mechanisms of Ovarian Cancer-Associated Cachexia. Endocrinology. 2023 11 20; 165(1).
    View in: PubMed
    Score: 0.187
  25. Kim HG, Huot JR, Pin F, Belcher DJ, Bonetto A, Nader GA. Metastatic or xenograft colorectal cancer models induce divergent anabolic deficits and expression of pro-inflammatory effectors of muscle wasting in a tumor-type-dependent manner. J Appl Physiol (1985). 2022 12 01; 133(6):1273-1283.
    View in: PubMed
    Score: 0.173
  26. Pin F, Jones AJ, Huot JR, Narasimhan A, Zimmers TA, Bonewald LF, Bonetto A. RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non-Metastatic Ovarian Cancer in Mice. J Bone Miner Res. 2022 03; 37(3):381-396.
    View in: PubMed
    Score: 0.163
  27. Rupert JE, Narasimhan A, Jengelley DHA, Jiang Y, Liu J, Au E, Silverman LM, Sandusky G, Bonetto A, Cao S, Lu X, O'Connell TM, Liu Y, Koniaris LG, Zimmers TA. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia. J Exp Med. 2021 06 07; 218(6).
    View in: PubMed
    Score: 0.158
  28. Kim HG, Huot JR, Pin F, Guo B, Bonetto A, Nader GA. Reduced rDNA transcription diminishes skeletal muscle ribosomal capacity and protein synthesis in cancer cachexia. FASEB J. 2021 02; 35(2):e21335.
    View in: PubMed
    Score: 0.154
  29. Pin F, Barreto R, Couch ME, Bonetto A, O'Connell TM. Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism. J Cachexia Sarcopenia Muscle. 2019 02; 10(1):140-154.
    View in: PubMed
    Score: 0.134
  30. Barreto R, Kitase Y, Matsumoto T, Pin F, Colston KC, Couch KE, O'Connell TM, Couch ME, Bonewald LF, Bonetto A. ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass. Sci Rep. 2017 10 31; 7(1):14470.
    View in: PubMed
    Score: 0.123
  31. Aversa Z, Bonetto A, Costelli P, Minero VG, Penna F, Baccino FM, Lucia S, Rossi Fanelli F, Muscaritoli M. ß-hydroxy-ß-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia. Int J Oncol. 2011 Mar; 38(3):713-20.
    View in: PubMed
    Score: 0.076
  32. Penna F, Bonetto A, Muscaritoli M, Costamagna D, Minero VG, Bonelli G, Rossi Fanelli F, Baccino FM, Costelli P. Muscle atrophy in experimental cancer cachexia: is the IGF-1 signaling pathway involved? Int J Cancer. 2010 Oct 01; 127(7):1706-17.
    View in: PubMed
    Score: 0.075
  33. Costelli P, Muscaritoli M, Bonetto A, Penna F, Reffo P, Bossola M, Bonelli G, Doglietto GB, Baccino FM, Rossi Fanelli F. Muscle myostatin signalling is enhanced in experimental cancer cachexia. Eur J Clin Invest. 2008 Jul; 38(7):531-8.
    View in: PubMed
    Score: 0.064
  34. Muscaritoli M, Costelli P, Aversa Z, Bonetto A, Baccino FM, Rossi Fanelli F. New strategies to overcome cancer cachexia: from molecular mechanisms to the 'Parallel Pathway'. Asia Pac J Clin Nutr. 2008; 17 Suppl 1:387-90.
    View in: PubMed
    Score: 0.062
  35. Costelli P, Muscaritoli M, Bossola M, Penna F, Reffo P, Bonetto A, Busquets S, Bonelli G, Lopez-Soriano FJ, Doglietto GB, Argilés JM, Baccino FM, Rossi Fanelli F. IGF-1 is downregulated in experimental cancer cachexia. Am J Physiol Regul Integr Comp Physiol. 2006 Sep; 291(3):R674-83.
    View in: PubMed
    Score: 0.055
  36. Huot JR, Baumfalk D, Resendiz A, Bonetto A, Smuder AJ, Penna F. Targeting Mitochondria and Oxidative Stress in Cancer- and Chemotherapy-Induced Muscle Wasting. Antioxid Redox Signal. 2023 02; 38(4-6):352-370.
    View in: PubMed
    Score: 0.044
  37. Jones AJ, Davis KP, Novinger LJ, Bonetto A, Mantravadi AV, Sim MW, Yesensky JA, Moore MG. Postoperative consequences of cancer cachexia after head and neck free flap reconstruction. Head Neck. 2022 07; 44(7):1665-1677.
    View in: PubMed
    Score: 0.042
  38. Aversa Z, Bonetto A, Penna F, Costelli P, Di Rienzo G, Lacitignola A, Baccino FM, Ziparo V, Mercantini P, Rossi Fanelli F, Muscaritoli M. Changes in myostatin signaling in non-weight-losing cancer patients. Ann Surg Oncol. 2012 Apr; 19(4):1350-6.
    View in: PubMed
    Score: 0.020
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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