Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

John Markley to Humans

This is a "connection" page, showing publications John Markley has written about Humans.

 
Connection Strength
 
 
 
0.354
 
  1. Aceti DJ, Ahmed H, Westler WM, Wu C, Dashti H, Tonelli M, Eghbalnia H, Amarasinghe GK, Markley JL. Fragment screening targeting Ebola virus nucleoprotein C-terminal domain identifies lead candidates. Antiviral Res. 2020 08; 180:104822.
    View in: PubMed
    Score: 0.017
  2. Cai K, Frederick RO, Markley JL. ISCU interacts with NFU1, and ISCU[4Fe-4S] transfers its Fe-S cluster to NFU1 leading to the production of holo-NFU1. J Struct Biol. 2020 05 01; 210(2):107491.
    View in: PubMed
    Score: 0.017
  3. Cai K, Markley JL. NMR as a Tool to Investigate the Processes of Mitochondrial and Cytosolic Iron-Sulfur Cluster Biosynthesis. Molecules. 2018 Aug 31; 23(9).
    View in: PubMed
    Score: 0.015
  4. Cai K, Frederick RO, Dashti H, Markley JL. Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering. Structure. 2018 08 07; 26(8):1127-1136.e4.
    View in: PubMed
    Score: 0.015
  5. Cai K, Frederick RO, Tonelli M, Markley JL. ISCU(M108I) and ISCU(D39V) Differ from Wild-Type ISCU in Their Failure To Form Cysteine Desulfurase Complexes Containing Both Frataxin and Ferredoxin. Biochemistry. 2018 03 06; 57(9):1491-1500.
    View in: PubMed
    Score: 0.014
  6. Cai K, Tonelli M, Frederick RO, Markley JL. Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis. Biochemistry. 2017 01 24; 56(3):487-499.
    View in: PubMed
    Score: 0.013
  7. Cai K, Liu G, Frederick RO, Xiao R, Montelione GT, Markley JL. Structural/Functional Properties of Human NFU1, an Intermediate [4Fe-4S] Carrier in Human Mitochondrial Iron-Sulfur Cluster Biogenesis. Structure. 2016 12 06; 24(12):2080-2091.
    View in: PubMed
    Score: 0.013
  8. Eghbalnia HR, Romero PR, Westler WM, Baskaran K, Ulrich EL, Markley JL. Increasing rigor in NMR-based metabolomics through validated and open source tools. Curr Opin Biotechnol. 2017 02; 43:56-61.
    View in: PubMed
    Score: 0.013
  9. Markley JL, Brüschweiler R, Edison AS, Eghbalnia HR, Powers R, Raftery D, Wishart DS. The future of NMR-based metabolomics. Curr Opin Biotechnol. 2017 02; 43:34-40.
    View in: PubMed
    Score: 0.013
  10. Alderson TR, Kim JH, Markley JL. Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes. Structure. 2016 07 06; 24(7):1014-30.
    View in: PubMed
    Score: 0.013
  11. Lee W, Tonelli M, Markley JL. NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy. Bioinformatics. 2015 Apr 15; 31(8):1325-7.
    View in: PubMed
    Score: 0.012
  12. Kim JH, Bothe JR, Alderson TR, Markley JL. Tangled web of interactions among proteins involved in iron-sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies. Biochim Biophys Acta. 2015 Jun; 1853(6):1416-28.
    View in: PubMed
    Score: 0.011
  13. Lee W, Hu K, Tonelli M, Bahrami A, Neuhardt E, Glass KC, Markley JL. Fast automated protein NMR data collection and assignment by ADAPT-NMR on Bruker spectrometers. J Magn Reson. 2013 Nov; 236:83-8.
    View in: PubMed
    Score: 0.011
  14. Lee W, Kim JH, Westler WM, Markley JL. PONDEROSA, an automated 3D-NOESY peak picking program, enables automated protein structure determination. Bioinformatics. 2011 Jun 15; 27(12):1727-8.
    View in: PubMed
    Score: 0.009
  15. Ellinger JJ, Lewis IA, Markley JL. Role of aminotransferases in glutamate metabolism of human erythrocytes. J Biomol NMR. 2011 Apr; 49(3-4):221-9.
    View in: PubMed
    Score: 0.009
  16. Lewis IA, Schommer SC, Markley JL. rNMR: open source software for identifying and quantifying metabolites in NMR spectra. Magn Reson Chem. 2009 Dec; 47 Suppl 1:S123-6.
    View in: PubMed
    Score: 0.008
  17. Markley JL, Aceti DJ, Bingman CA, Fox BG, Frederick RO, Makino S, Nichols KW, Phillips GN, Primm JG, Sahu SC, Vojtik FC, Volkman BF, Wrobel RL, Zolnai Z. The Center for Eukaryotic Structural Genomics. J Struct Funct Genomics. 2009 Apr; 10(2):165-79.
    View in: PubMed
    Score: 0.008
  18. Assadi-Porter FM, Tonelli M, Maillet E, Hallenga K, Benard O, Max M, Markley JL. Direct NMR detection of the binding of functional ligands to the human sweet receptor, a heterodimeric family 3 GPCR. J Am Chem Soc. 2008 Jun 11; 130(23):7212-3.
    View in: PubMed
    Score: 0.007
  19. Song J, Markley JL. Three-dimensional structure determined for a subunit of human tRNA splicing endonuclease (Sen15) reveals a novel dimeric fold. J Mol Biol. 2007 Feb 09; 366(1):155-64.
    View in: PubMed
    Score: 0.007
  20. Vinarov DA, Loushin Newman CL, Markley JL. Wheat germ cell-free platform for eukaryotic protein production. FEBS J. 2006 Sep; 273(18):4160-9.
    View in: PubMed
    Score: 0.006
  21. Song J, Tyler RC, Wrobel RL, Frederick RO, Vojtek FC, Jeon WB, Lee MS, Markley JL. Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein. Protein Sci. 2005 Apr; 14(4):1059-63.
    View in: PubMed
    Score: 0.006
  22. Assadi-Porter FM, Abildgaard F, Blad H, Cornilescu CC, Markley JL. Brazzein, a small, sweet protein: effects of mutations on its structure, dynamics and functional properties. Chem Senses. 2005 Jan; 30 Suppl 1:i90-1.
    View in: PubMed
    Score: 0.006
  23. Machonkin TE, Westler WM, Markley JL. Strategy for the study of paramagnetic proteins with slow electronic relaxation rates by nmr spectroscopy: application to oxidized human [2Fe-2S] ferredoxin. J Am Chem Soc. 2004 May 05; 126(17):5413-26.
    View in: PubMed
    Score: 0.006
  24. Machonkin TE, Westler WM, Markley JL. (13)C[(13)C] 2D NMR: a novel strategy for the study of paramagnetic proteins with slow electronic relaxation rates. J Am Chem Soc. 2002 Apr 03; 124(13):3204-5.
    View in: PubMed
    Score: 0.005
  25. Evans CM, Phillips M, Malone KL, Tonelli M, Cornilescu G, Cornilescu C, Holton SJ, Gorjánácz M, Wang L, Carlson S, Gay JC, Nix JC, Demeler B, Markley JL, Glass KC. Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain. Int J Mol Sci. 2021 Aug 24; 22(17).
    View in: PubMed
    Score: 0.005
  26. Lloyd JT, McLaughlin K, Lubula MY, Gay JC, Dest A, Gao C, Phillips M, Tonelli M, Cornilescu G, Marunde MR, Evans CM, Boyson SP, Carlson S, Keogh MC, Markley JL, Frietze S, Glass KC. Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain. J Med Chem. 2020 11 12; 63(21):12799-12813.
    View in: PubMed
    Score: 0.004
  27. Assadi-Porter FM, Aceti DJ, Cheng H, Markley JL. Efficient production of recombinant brazzein, a small, heat-stable, sweet-tasting protein of plant origin. Arch Biochem Biophys. 2000 Apr 15; 376(2):252-8.
    View in: PubMed
    Score: 0.004
  28. Assadi-Porter FM, Aceti DJ, Markley JL. Sweetness determinant sites of brazzein, a small, heat-stable, sweet-tasting protein. Arch Biochem Biophys. 2000 Apr 15; 376(2):259-65.
    View in: PubMed
    Score: 0.004
  29. Xia B, Jenk D, LeMaster DM, Westler WM, Markley JL. Electron-nuclear interactions in two prototypical [2Fe-2S] proteins: selective (chiral) deuteration and analysis of (1)H and (2)H NMR signals from the alpha and beta hydrogens of cysteinyl residues that ligate the iron in the active sites of human ferredoxin and Anabaena 7120 vegetative ferredoxin. Arch Biochem Biophys. 2000 Jan 15; 373(2):328-34.
    View in: PubMed
    Score: 0.004
  30. Bortnov V, Tonelli M, Lee W, Lin Z, Annis DS, Demerdash ON, Bateman A, Mitchell JC, Ge Y, Markley JL, Mosher DF. Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum. Nat Commun. 2019 12 09; 10(1):5612.
    View in: PubMed
    Score: 0.004
  31. Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M, Kory N, Tsherniak A, Santagata S, Whitesell L, Ghobrial IM, Markley JL, Lindquist S, Golub TR. Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nat Chem Biol. 2019 07; 15(7):681-689.
    View in: PubMed
    Score: 0.004
  32. Shrestha OK, Sharma R, Tomiczek B, Lee W, Tonelli M, Cornilescu G, Stolarska M, Nierzwicki L, Czub J, Markley JL, Marszalek J, Ciesielski SJ, Craig EA. Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70. PLoS One. 2019; 14(5):e0217098.
    View in: PubMed
    Score: 0.004
  33. Adams PD, Afonine PV, Baskaran K, Berman HM, Berrisford J, Bricogne G, Brown DG, Burley SK, Chen M, Feng Z, Flensburg C, Gutmanas A, Hoch JC, Ikegawa Y, Kengaku Y, Krissinel E, Kurisu G, Liang Y, Liebschner D, Mak L, Markley JL, Moriarty NW, Murshudov GN, Noble M, Peisach E, Persikova I, Poon BK, Sobolev OV, Ulrich EL, Velankar S, Vonrhein C, Westbrook J, Wojdyr M, Yokochi M, Young JY. Announcing mandatory submission of PDBx/mmCIF format files for crystallographic depositions to the Protein Data Bank (PDB). Acta Crystallogr D Struct Biol. 2019 Apr 01; 75(Pt 4):451-454.
    View in: PubMed
    Score: 0.004
  34. Volkman BF, Anderson ME, Clark KD, Hayakawa Y, Strand MR, Markley JL. Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens. J Biol Chem. 1999 Feb 19; 274(8):4493-6.
    View in: PubMed
    Score: 0.004
  35. Kaslik G, Westler WM, Gráf L, Markley JL. Properties of the His57-Asp102 dyad of rat trypsin D189S in the zymogen, activated enzyme, and alpha1-proteinase inhibitor complexed forms. Arch Biochem Biophys. 1999 Feb 15; 362(2):254-64.
    View in: PubMed
    Score: 0.004
  36. Chae YK, Abildgaard F, Chapman ER, Markley JL. Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy. J Biol Chem. 1998 Oct 02; 273(40):25659-63.
    View in: PubMed
    Score: 0.004
  37. Reidenbach AG, Kemmerer ZA, Aydin D, Jochem A, McDevitt MT, Hutchins PD, Stark JL, Stefely JA, Reddy T, Hebert AS, Wilkerson EM, Johnson IE, Bingman CA, Markley JL, Coon JJ, Dal Peraro M, Pagliarini DJ. Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family. Cell Chem Biol. 2018 02 15; 25(2):154-165.e11.
    View in: PubMed
    Score: 0.004
  38. Wyche TP, Alvarenga RFR, Piotrowski JS, Duster MN, Warrack SR, Cornilescu G, De Wolfe TJ, Hou Y, Braun DR, Ellis GA, Simpkins SW, Nelson J, Myers CL, Steele J, Mori H, Safdar N, Markley JL, Rajski SR, Bugni TS. Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin. ACS Chem Biol. 2017 09 15; 12(9):2287-2295.
    View in: PubMed
    Score: 0.003
  39. Burley SK, Berman HM, Kleywegt GJ, Markley JL, Nakamura H, Velankar S. Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive. Methods Mol Biol. 2017; 1607:627-641.
    View in: PubMed
    Score: 0.003
  40. Berman HM, Burley SK, Kleywegt GJ, Markley JL, Nakamura H, Velankar S. The archiving and dissemination of biological structure data. Curr Opin Struct Biol. 2016 10; 40:17-22.
    View in: PubMed
    Score: 0.003
  41. Kim S, Natesan S, Cornilescu G, Carlson S, Tonelli M, McClurg UL, Binda O, Robson CN, Markley JL, Balaz S, Glass KC. Mechanism of Histone H3K4me3 Recognition by the Plant Homeodomain of Inhibitor of Growth 3. J Biol Chem. 2016 08 26; 291(35):18326-41.
    View in: PubMed
    Score: 0.003
  42. Singarapu KK, Tonelli M, Markley JL, Assadi-Porter FM. Structure-function relationships of brazzein variants with altered interactions with the human sweet taste receptor. Protein Sci. 2016 Mar; 25(3):711-9.
    View in: PubMed
    Score: 0.003
  43. Sali A, Berman HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, Markley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di Maio F, Ferrin TE, Grünewald K, Gutmanas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, Marti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD. Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. Structure. 2015 Jul 07; 23(7):1156-67.
    View in: PubMed
    Score: 0.003
  44. Huang Y, Nokhrin S, Hassanzadeh-Ghassabeh G, Yu CH, Yang H, Barry AN, Tonelli M, Markley JL, Muyldermans S, Dmitriev OY, Lutsenko S. Interactions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding. J Biol Chem. 2014 Nov 21; 289(47):32682-93.
    View in: PubMed
    Score: 0.003
  45. Beebe ET, Makino S, Markley JL, Fox BG. Automated cell-free protein production methods for structural studies. Methods Mol Biol. 2014; 1140:117-35.
    View in: PubMed
    Score: 0.003
  46. Poplawski A, Hu K, Lee W, Natesan S, Peng D, Carlson S, Shi X, Balaz S, Markley JL, Glass KC. Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain. J Mol Biol. 2014 Apr 17; 426(8):1661-76.
    View in: PubMed
    Score: 0.003
  47. Cornilescu CC, Cornilescu G, Rao H, Porter SF, Tonelli M, DeRider ML, Markley JL, Assadi-Porter FM. Temperature-dependent conformational change affecting Tyr11 and sweetness loops of brazzein. Proteins. 2013 Jun; 81(6):919-25.
    View in: PubMed
    Score: 0.003
  48. Venkitakrishnan RP, Benard O, Max M, Markley JL, Assadi-Porter FM. Use of NMR saturation transfer difference spectroscopy to study ligand binding to membrane proteins. Methods Mol Biol. 2012; 914:47-63.
    View in: PubMed
    Score: 0.002
  49. Hallows WC, Yu W, Smith BC, Devries MK, Devires MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell. 2011 Jan 21; 41(2):139-49.
    View in: PubMed
    Score: 0.002
  50. Assadi-Porter FM, Maillet EL, Radek JT, Quijada J, Markley JL, Max M. Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor. J Mol Biol. 2010 May 14; 398(4):584-99.
    View in: PubMed
    Score: 0.002
  51. Lewis IA, Campanella ME, Markley JL, Low PS. Role of band 3 in regulating metabolic flux of red blood cells. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18515-20.
    View in: PubMed
    Score: 0.002
  52. Assadi-Porter FM, Tonelli M, Maillet EL, Markley JL, Max M. Interactions between the human sweet-sensing T1R2-T1R3 receptor and sweeteners detected by saturation transfer difference NMR spectroscopy. Biochim Biophys Acta. 2010 Feb; 1798(2):82-6.
    View in: PubMed
    Score: 0.002
  53. Frederick RO, Bergeman L, Blommel PG, Bailey LJ, McCoy JG, Song J, Meske L, Bingman CA, Riters M, Dillon NA, Kunert J, Yoon JW, Lim A, Cassidy M, Bunge J, Aceti DJ, Primm JG, Markley JL, Phillips GN, Fox BG. Small-scale, semi-automated purification of eukaryotic proteins for structure determination. J Struct Funct Genomics. 2007 Dec; 8(4):153-66.
    View in: PubMed
    Score: 0.002
  54. Phillips GN, Fox BG, Markley JL, Volkman BF, Bae E, Bitto E, Bingman CA, Frederick RO, McCoy JG, Lytle BL, Pierce BS, Song J, Twigger SN. Structures of proteins of biomedical interest from the Center for Eukaryotic Structural Genomics. J Struct Funct Genomics. 2007 Sep; 8(2-3):73-84.
    View in: PubMed
    Score: 0.002
  55. Smith DW, Johnson KA, Bingman CA, Aceti DJ, Blommel PG, Wrobel RL, Frederick RO, Zhao Q, Sreenath H, Fox BG, Volkman BF, Jeon WB, Newman CS, Ulrich EL, Hegeman AD, Kimball T, Thao S, Sussman MR, Markley JL, Phillips GN. Crystal structure of At2g03760, a putative steroid sulfotransferase from Arabidopsis thaliana. Proteins. 2004 Dec 01; 57(4):854-7.
    View in: PubMed
    Score: 0.001
  56. Jin Z, Danilova V, Assadi-Porter FM, Markley JL, Hellekant G. Monkey electrophysiological and human psychophysical responses to mutants of the sweet protein brazzein: delineating brazzein sweetness. Chem Senses. 2003 Jul; 28(6):491-8.
    View in: PubMed
    Score: 0.001
  57. Kuloglu ES, McCaslin DR, Markley JL, Volkman BF. Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions. J Biol Chem. 2002 May 17; 277(20):17863-70.
    View in: PubMed
    Score: 0.001
  58. Kuloglu ES, McCaslin DR, Kitabwalla M, Pauza CD, Markley JL, Volkman BF. Monomeric solution structure of the prototypical 'C' chemokine lymphotactin. Biochemistry. 2001 Oct 23; 40(42):12486-96.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)