Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.
Maier H, Colbert J, Fitzsimmons D, Clark DR, Hagman J. Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Mol Cell Biol. 2003 Mar; 23(6):1946-60.
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Animals
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Antigens, CD
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Binding Sites
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B-Lymphocytes
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Bone Marrow Cells
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CD79 Antigens
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Cell Lineage
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CpG Islands
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DNA Methylation
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DNA-Binding Proteins
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Gene Expression Regulation, Neoplastic
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Humans
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Macromolecular Substances
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Mice
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Mice, Inbred BALB C
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Mice, Inbred C57BL
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Mice, Knockout
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PAX5 Transcription Factor
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Plasma Cells
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Plasmacytoma
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Promoter Regions, Genetic
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Proto-Oncogene Protein c-ets-1
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-ets
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Receptors, Antigen, B-Cell
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Recombinant Fusion Proteins
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Specific Pathogen-Free Organisms
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Transcription Factors
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Transcription, Genetic
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Transfection
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Tumor Cells, Cultured