DouglasShepherdDouglas P Shepherd39.74545800000000-104.839369100000007892Shepherd, DouglasPAsst Professor Adjointprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 128189125936616Shepherd DPhysics of life reviewsShepherd D. Life away from the coverslip: Comment on "Extracting physics of life at the molecular level: A review of single-molecule data analyses" by W. Colomb and S.K. Sarkar. Phys Life Rev. 2015 Jun; 13:144-5.Phys Life Rev2015-04-23T00:00:002015Life away from the coverslip: Comment on "Extracting physics of life at the molecular level: A review of single-molecule data analyses" by W. Colomb and S.K. Sarkar.1Professor3Asst Professor2Assoc Professor4Instructor2022-06-30NIHABMAN, STEVEN HERBERT2001-06-20Role of VEGF in Perinatal HypertensionR01HL068702Authorship 166504528717817Singh JN, Nowlin TM, Seedorf GJ, Abman SH, Shepherd DPJournal of biomedical opticsSingh JN, Nowlin TM, Seedorf GJ, Abman SH, Shepherd DP. Quantifying three-dimensional rodent retina vascular development using optical tissue clearing and light-sheet microscopy. J Biomed Opt. 2017 07 01; 22(7):76011.J Biomed Opt2017-07-01T00:00:002017Quantifying three-dimensional rodent retina vascular development using optical tissue clearing and light-sheet microscopy.MariaCainoMaria Cecilia Caino39.74545800000000-104.8393691000000013111Caino, MariaAssociate ProfessorAuthorship 169932928931809Ryan DP, Gould EA, Seedorf GJ, Masihzadeh O, Abman SH, Vijayaraghavan S, Macklin WB, Restrepo D, Shepherd DPNature communicationsRyan DP, Gould EA, Seedorf GJ, Masihzadeh O, Abman SH, Vijayaraghavan S, Macklin WB, Restrepo D, Shepherd DP. Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy. Nat Commun. 2017 09 20; 8(1):612.Nat Commun2017-09-20T00:00:002017Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy.Authorship 176738329436368Gould EA, Busquet N, Shepherd D, Dietz RM, Herson PS, Simoes de Souza FM, Li A, George NM, Restrepo D, Macklin WBeLifeGould EA, Busquet N, Shepherd D, Dietz RM, Herson PS, Simoes de Souza FM, Li A, George NM, Restrepo D, Macklin WB. Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone. Elife. 2018 02 13; 7.Elife2018-02-13T00:00:002018Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone.Authorship 183429429959206Munsky B, Li G, Fox ZR, Shepherd DP, Neuert GProceedings of the National Academy of Sciences of the United States of AmericaMunsky B, Li G, Fox ZR, Shepherd DP, Neuert G. Distribution shapes govern the discovery of predictive models for gene regulation. Proc Natl Acad Sci U S A. 2018 07 17; 115(29):7533-7538.Proc Natl Acad Sci U S A2018-06-29T00:00:002018Distribution shapes govern the discovery of predictive models for gene regulation.D008856Procedures2654180.848101Microscopy, FluorescenceD021621ObjectsProcedures2625110.749847Imaging, Three-DimensionalD012171Anatomy26530.948336Retinal VesselsD012031Concepts & IdeasOccupations23310.969958Refractometry2019-07-08NIHABMAN, STEVEN HERBERT2018-09-20Role of VEGF in Perinatal HypertensionR56HL068702D061848Procedures46590.939303Optical ImagingCEDC-BioengineeringPULM&SLEEPMEDSOM-PHARM General OperationsSOM-PHYS General OperationsSOM-RAD General OperationsBiochemistrySOM-Cell and Devopmental BioSOM-PEDSSOP-AdministrationUniversity of Colorado BoulderUniversity of Colorado Denver - Anschutz Medical CampusEmilyGibsonEmily A Gibson39.74773620000000-104.839213600000001009Gibson, EmilyAssociate ProfessorRonaldFreundRonald K Freund39.74545800000000-104.839369100000001098Freund, RonaldInstructorSukumarVijayaraghavanSukumar Vijayaraghavan39.74545800000000-104.839369100000001415Vijayaraghavan, SukumarProfessorAndrewThorburnAndrew M Thorburn39.74545800000000-104.839369100000002196Thorburn, AndrewProfessor-ClinicalDiegoRestrepoDiego Restrepo39.74389450000000-104.83943520000000204Restrepo, DiegoProfessorAmyPalmerAmy E Palmer40.00830860000000-105.249067200000002335Palmer, AmyProfessorWendyMacklinWendy Macklin39.74389450000000-104.839435200000003251Macklin, WendyDistinguished ProfessorPacoHersonPaco Sam Herson39.74545800000000-104.839369100000005282Herson, PacoProfessor AdjointStevenAbmanSteven H Abman39.74403510000000-104.83605940000000518Abman, StevenProfessorJenniferSandersonJennifer L Sanderson39.74545800000000-104.839369100000003175Sanderson, JenniferInstructorUdayaKompellaUdaya B. Kompella39.74688660000000-104.838256700000004276Kompella, UdayaProfessorCo-Principal InvestigatorCo-Principal InvestigatorAuthorship 210827431649121Kim C, Seedorf GJ, Abman SH, Shepherd DPBiology openKim C, Seedorf GJ, Abman SH, Shepherd DP. Heterogeneous response of endothelial cells to insulin-like growth factor 1 treatment is explained by spatially clustered sub-populations. Biol Open. 2019 Nov 04; 8(11).Biol Open2019-11-04T00:00:002019Heterogeneous response of endothelial cells to insulin-like growth factor 1 treatment is explained by spatially clustered sub-populations.Authorship 216724632101461Seedorf G, Kim C, Wallace B, Mandell EW, Nowlin T, Shepherd D, Abman SHAmerican journal of respiratory and critical care medicineSeedorf G, Kim C, Wallace B, Mandell EW, Nowlin T, Shepherd D, Abman SH. rhIGF-1/BP3 Preserves Lung Growth and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 05 01; 201(9):1120-1134.Am J Respir Crit Care Med2020-05-01T00:00:002020rhIGF-1/BP3 Preserves Lung Growth and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia.12800 E 19th Ave2RC1NResearch North Tower12800 E 19th AveAurora80045-2537CO0.6470540.012360958research areas0.6908110.040895613coauthor of9.373031.1413660similar to1113selected publicationsAuthorship 100652123577771Shepherd DP, Li N, Micheva-Viteva SN, Munsky B, Hong-Geller E, Werner JHAnalytical chemistryShepherd DP, Li N, Micheva-Viteva SN, Munsky B, Hong-Geller E, Werner JH. Counting small RNA in pathogenic bacteria. Anal Chem. 2013 May 21; 85(10):4938-43.Anal Chem2013-04-25T00:00:002013Counting small RNA in pathogenic bacteria.Authorship 243273434221689Brown PT, Kruithoff R, Seedorf GJ, Shepherd DPBiomedical optics expressBrown PT, Kruithoff R, Seedorf GJ, Shepherd DP. Multicolor structured illumination microscopy and quantitative control of polychromatic light with a digital micromirror device. Biomed Opt Express. 2021 Jun 01; 12(6):3700-3716.Biomed Opt Express2021-06-01T00:00:002021Multicolor structured illumination microscopy and quantitative control of polychromatic light with a digital micromirror device.2024-09-14NIHSHEPHERD, DOUGLAS2021-09-15Scalable 3D molecular imaging and data analysis for cell census generationRF1MH128867Principal InvestigatorHouchunHuHouchun Hu22539Hu, HouchunProfessorAuthorship 26124413Authorship 2616411035519247Supekar OD, Sias A, Hansen SR, Martinez G, Peet GC, Peng X, Bright VM, Hughes EG, Restrepo D, Shepherd DP, Welle CG, Gopinath JT, Gibson EABiomedical optics expressSupekar OD, Sias A, Hansen SR, Martinez G, Peet GC, Peng X, Bright VM, Hughes EG, Restrepo D, Shepherd DP, Welle CG, Gopinath JT, Gibson EA. Miniature structured illumination microscope for in vivo 3D imaging of brain structures with optical sectioning. Biomed Opt Express. 2022 Apr 01; 13(4):2530-2541.Biomed Opt Express2022-03-29T00:00:002022Miniature structured illumination microscope for in vivo 3D imaging of brain structures with optical sectioning.33674797Pinkard H, Stuurman N, Ivanov IE, Anthony NM, Ouyang W, Li B, Yang B, Tsuchida MA, Chhun B, Zhang G, Mei R, Anderson M, Shepherd DP, Hunt-Isaak I, Dunn RL, Jahr W, Kato S, Royer LA, Thiagarajah JR, Eliceiri KW, Lundberg E, Mehta SB, Waller LNature methodsPinkard H, Stuurman N, Ivanov IE, Anthony NM, Ouyang W, Li B, Yang B, Tsuchida MA, Chhun B, Zhang G, Mei R, Anderson M, Shepherd DP, Hunt-Isaak I, Dunn RL, Jahr W, Kato S, Royer LA, Thiagarajah JR, Eliceiri KW, Lundberg E, Mehta SB, Waller L. Pycro-Manager: open-source software for customized and reproducible microscope control. Nat Methods. 2021 03; 18(3):226-228.Nat Methods2021-03-01T00:00:002021Pycro-Manager: open-source software for customized and reproducible microscope control.Authorship 2738791436280718Chen B, Chang BJ, Roudot P, Zhou F, Sapoznik E, Marlar-Pavey M, Hayes JB, Brown PT, Zeng CW, Lambert T, Friedman JR, Zhang CL, Burnette DT, Shepherd DP, Dean KM, Fiolka RPNature methodsChen B, Chang BJ, Roudot P, Zhou F, Sapoznik E, Marlar-Pavey M, Hayes JB, Brown PT, Zeng CW, Lambert T, Friedman JR, Zhang CL, Burnette DT, Shepherd DP, Dean KM, Fiolka RP. Resolution doubling in light-sheet microscopy via oblique plane structured illumination. Nat Methods. 2022 11; 19(11):1419-1426.Nat Methods2022-10-24T00:00:002022Resolution doubling in light-sheet microscopy via oblique plane structured illumination.true1ProfessorProfessorAuthorship 297163638106139Saurabh A, Brown PT, Bryan JS, Fox ZR, Kruithoff R, Shepherd DP, Press? SbioRxiv : the preprint server for biologySaurabh A, Brown PT, Bryan JS, Fox ZR, Kruithoff R, Shepherd DP, Press? S. A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation. bioRxiv. 2023 Dec 11.bioRxiv2023-12-11T00:00:002023A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.true1InstructorInstructortrue1Distinguished ProfessorDistinguished Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Asst Professor AdjointAsst Professor Adjointtrue1InstructorInstructortrue1Professor-ClinicalProfessor-Clinicaltrue1Professor AdjointProfessor Adjointtrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor