Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

James Bridges to Mice

This is a "connection" page, showing publications James Bridges has written about Mice.

 
Connection Strength
 
 
 
0.628
 
  1. Bridges JP, Weaver TE. Use of transgenic mice to study lung morphogenesis and function. ILAR J. 2006; 47(1):22-31.
    View in: PubMed
    Score: 0.068
  2. Bridges JP, Safina C, Pirard B, Brown K, Filuta A, Panchanathan R, Bouhelal R, Reymann N, Patel S, Seuwen K, Miller WE, Ludwig MG. Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation mechanism. Elife. 2022 09 08; 11.
    View in: PubMed
    Score: 0.054
  3. Rindler TN, Brown KM, Stockman CA, van Lieshout LP, Martin EP, Weaver TE, Zacharias WJ, Wootton SK, Whitsett JA, Bridges JP. Efficient Transduction of Alveolar Type 2 Cells with Adeno-associated Virus for the Study of Lung Regeneration. Am J Respir Cell Mol Biol. 2021 07; 65(1):118-121.
    View in: PubMed
    Score: 0.050
  4. Bridges JP, Sudha P, Lipps D, Wagner A, Guo M, Du Y, Brown K, Filuta A, Kitzmiller J, Stockman C, Chen X, Weirauch MT, Jobe AH, Whitsett JA, Xu Y. Glucocorticoid regulates mesenchymal cell differentiation required for perinatal lung morphogenesis and function. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L239-L255.
    View in: PubMed
    Score: 0.046
  5. Ludwig MG, Seuwen K, Bridges JP. Adhesion GPCR Function in Pulmonary Development and Disease. Handb Exp Pharmacol. 2016; 234:309-327.
    View in: PubMed
    Score: 0.034
  6. Bridges JP, Schehr A, Wang Y, Huo L, Besnard V, Ikegami M, Whitsett JA, Xu Y. Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation. PLoS One. 2014; 9(5):e91376.
    View in: PubMed
    Score: 0.031
  7. Bridges JP, Ludwig MG, Mueller M, Kinzel B, Sato A, Xu Y, Whitsett JA, Ikegami M. Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. Am J Respir Cell Mol Biol. 2013 Sep; 49(3):348-57.
    View in: PubMed
    Score: 0.029
  8. Bridges JP, Lin S, Ikegami M, Shannon JM. Conditional hypoxia inducible factor-1a induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol. 2012 Feb 01; 362(1):24-41.
    View in: PubMed
    Score: 0.026
  9. Bridges JP, Ikegami M, Brilli LL, Chen X, Mason RJ, Shannon JM. LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice. J Clin Invest. 2010 May; 120(5):1736-48.
    View in: PubMed
    Score: 0.023
  10. Redente EF, Song T, Javkhlan N, Edelman BL, Foster DG, Wilson JA, Chakraborty S, Cooley JC, Gaurav R, Saguthi S, Seibold MA, Blumhagen RZ, Schwartz DA, Yang IV, Matsuda J, Bridges JP, Zemans RL, Tuder RM, Riches DWH. Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition. Nat Commun. 2026 Feb 28; 17(1).
    View in: PubMed
    Score: 0.017
  11. Bridges JP, Xu Y, Na CL, Wong HR, Weaver TE. Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C. J Cell Biol. 2006 Jan 30; 172(3):395-407.
    View in: PubMed
    Score: 0.017
  12. Wilburn AN, Korkmaz RÜ, McAlees JW, Hargis JM, Shirdel S, Lingel I, Watanabe-Chailland M, Romick-Rosendale L, Schmudde I, Bridges JP, Chougnet CA, Deshmukh H, Zacharias WJ, Köhl J, Konig P, Laumonnier Y, Rothenberg M, Haslam DB, Lewkowich IP. Maternal antibiotic exposure-mediated alterations in basal, and allergen-induced lung function are associated with altered recruitment of eosinophils to the developing lung. Front Immunol. 2025; 16:1715675.
    View in: PubMed
    Score: 0.017
  13. Leiss V, Pexa K, Nowacki A, Bridges JP, Duckworth-Mothes B, Ammon-Treiber S, Novakovic A, Zeyer F, Wolburg H, Fallier-Becker P, Piekorz RP, Schwab M, Quintanilla-Martínez L, Beer-Hammer S, Nürnberg B. Gai2 Signaling Regulates Neonatal Respiratory Adaptation. Int J Mol Sci. 2025 Nov 01; 26(21).
    View in: PubMed
    Score: 0.017
  14. Lee E, Williams KJ, McCarthy C, Bridges JP, Redente EF, de Aguiar Vallim TQ, Barrington RA, Wang T, Tarling EJ. Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis. J Lipid Res. 2024 02; 65(2):100496.
    View in: PubMed
    Score: 0.015
  15. Toth A, Kannan P, Snowball J, Kofron M, Wayman JA, Bridges JP, Miraldi ER, Swarr D, Zacharias WJ. Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration. Nat Commun. 2023 12 19; 14(1):8452.
    View in: PubMed
    Score: 0.015
  16. Bridges JP, Wert SE, Nogee LM, Weaver TE. Expression of a human surfactant protein C mutation associated with interstitial lung disease disrupts lung development in transgenic mice. J Biol Chem. 2003 Dec 26; 278(52):52739-46.
    View in: PubMed
    Score: 0.015
  17. Sitaraman S, Martin EP, Na CL, Zhao S, Green J, Deshmukh H, Perl AT, Bridges JP, Xu Y, Weaver TE. Surfactant protein C mutation links postnatal type 2 cell dysfunction to adult disease. JCI Insight. 2021 07 22; 6(14).
    View in: PubMed
    Score: 0.013
  18. Oherle K, Acker E, Bonfield M, Wang T, Gray J, Lang I, Bridges J, Lewkowich I, Xu Y, Ahlfeld S, Zacharias W, Alenghat T, Deshmukh H. Insulin-like Growth Factor 1 Supports a Pulmonary Niche that Promotes Type 3 Innate Lymphoid Cell Development in Newborn Lungs. Immunity. 2020 02 18; 52(2):275-294.e9.
    View in: PubMed
    Score: 0.011
  19. Sitaraman S, Na CL, Yang L, Filuta A, Bridges JP, Weaver TE. Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome. Sci Rep. 2019 08 29; 9(1):12509.
    View in: PubMed
    Score: 0.011
  20. Balczon R, Pittet JF, Wagener BM, Moser SA, Voth S, Vorhees CV, Williams MT, Bridges JP, Alvarez DF, Koloteva A, Xu Y, Zha XM, Audia JP, Stevens T, Lin MT. Infection-induced endothelial amyloids impair memory. FASEB J. 2019 09; 33(9):10300-10314.
    View in: PubMed
    Score: 0.011
  21. Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, Zhou Y, Wang J, Wu L, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, Watanabe M, Romick-Rosendale LE, Harada H, Shih LY, Tse W, Bridges JP, Caligiuri MA, Huang T, Zheng Y, Witte DP, Wang QF, Qu CK, Salomonis N, Grimes HL, Nimer SD, Xiao Z, Huang G. Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes. Cancer Discov. 2018 11; 8(11):1438-1457.
    View in: PubMed
    Score: 0.010
  22. McCarthy C, Lee E, Bridges JP, Sallese A, Suzuki T, Woods JC, Bartholmai BJ, Wang T, Chalk C, Carey BC, Arumugam P, Shima K, Tarling EJ, Trapnell BC. Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis. Nat Commun. 2018 08 07; 9(1):3127.
    View in: PubMed
    Score: 0.010
  23. Moreno-Fernandez ME, Giles DA, Stankiewicz TE, Sheridan R, Karns R, Cappelletti M, Lampe K, Mukherjee R, Sina C, Sallese A, Bridges JP, Hogan SP, Aronow BJ, Hoebe K, Divanovic S. Peroxisomal ß-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease. JCI Insight. 2018 03 22; 3(6).
    View in: PubMed
    Score: 0.010
  24. Wang J, Hayashi Y, Yokota A, Xu Z, Zhang Y, Huang R, Yan X, Liu H, Ma L, Azam M, Bridges JP, Cancelas JA, Kalfa TA, An X, Xiao Z, Huang G. Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models. Haematologica. 2018 01; 103(1):40-50.
    View in: PubMed
    Score: 0.010
  25. Huang R, Hayashi Y, Yan X, Bu J, Wang J, Zhang Y, Zhou Y, Tang Y, Wu L, Xu Z, Liu X, Wang Q, Zhou J, Xiao Z, Bridges JP, Marsh RA, Zhang K, Jordan MB, Li Y, Huang G. HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis. Haematologica. 2017 11; 102(11):1956-1968.
    View in: PubMed
    Score: 0.010
  26. Sallese A, Suzuki T, McCarthy C, Bridges J, Filuta A, Arumugam P, Shima K, Ma Y, Wessendarp M, Black D, Chalk C, Carey B, Trapnell BC. Targeting cholesterol homeostasis in lung diseases. Sci Rep. 2017 08 31; 7(1):10211.
    View in: PubMed
    Score: 0.010
  27. Du Y, Kitzmiller JA, Sridharan A, Perl AK, Bridges JP, Misra RS, Pryhuber GS, Mariani TJ, Bhattacharya S, Guo M, Potter SS, Dexheimer P, Aronow B, Jobe AH, Whitsett JA, Xu Y. Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development. Thorax. 2017 May; 72(5):481-484.
    View in: PubMed
    Score: 0.009
  28. Saito A, Nikolaidis NM, Amlal H, Uehara Y, Gardner JC, LaSance K, Pitstick LB, Bridges JP, Wikenheiser-Brokamp KA, McGraw DW, Woods JC, Sabbagh Y, Schiavi SC, Altinisik G, Jakopovic M, Inoue Y, McCormack FX. Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment. Sci Transl Med. 2015 Nov 11; 7(313):313ra181.
    View in: PubMed
    Score: 0.008
  29. Bittencourt FM, Wu SE, Bridges JP, Miller WE. The M33 G protein-coupled receptor encoded by murine cytomegalovirus is dispensable for hematogenous dissemination but is required for growth within the salivary gland. J Virol. 2014 Oct; 88(20):11811-24.
    View in: PubMed
    Score: 0.008
  30. Young LR, Gulleman PM, Bridges JP, Weaver TE, Deutsch GH, Blackwell TS, McCormack FX. The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome. Am J Respir Crit Care Med. 2012 Nov 15; 186(10):1014-24.
    View in: PubMed
    Score: 0.007
  31. Wang M, Bridges JP, Na CL, Xu Y, Weaver TE. Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C. J Biol Chem. 2009 Nov 27; 284(48):33377-83.
    View in: PubMed
    Score: 0.006
  32. Ahmad A, Ahmad S, Glover L, Miller SM, Shannon JM, Guo X, Franklin WA, Bridges JP, Schaack JB, Colgan SP, White CW. Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10684-9.
    View in: PubMed
    Score: 0.005
  33. Dong M, Bridges JP, Apsley K, Xu Y, Weaver TE. ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol Biol Cell. 2008 Jun; 19(6):2620-30.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)