 Connection
Sylvie Kandel to Cytochrome P-450 CYP3A
This is a "connection" page, showing publications Sylvie Kandel has written about Cytochrome P-450 CYP3A.
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Connection Strength |
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2.159 |
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Kandel SE, Lampe JN. Inhibition of CYP3A7 DHEA-S Oxidation by Lopinavir and Ritonavir: An Alternative Mechanism for Adrenal Impairment in HIV Antiretroviral-Treated Neonates. Chem Res Toxicol. 2021 04 19; 34(4):1150-1160.
Score: 0.639
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Kandel SE, Han LW, Mao Q, Lampe JN. Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7. Drug Metab Dispos. 2017 12; 45(12):1266-1275.
Score: 0.502
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Gracey EG, Kandel SE, Lampe JN. A CYP3A7 metabolically competent human induced pluripotent stem cell-derived hepatocyte-like cell (hHLC3A7) model for drug safety assessment in the newborn. Drug Metab Dispos. 2026 Jun; 54(6):100314.
Score: 0.227
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Work HM, Kandel SE, Lampe JN. Comparison of the CYP3A Selective Inhibitors CYP3cide, Clobetasol, and Azamulin for Their Potential to Distinguish CYP3A7 Activity in the Presence of CYP3A4/5. Drug Metab Dispos. 2024 10 16; 52(11):1224-1233.
Score: 0.204
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Kandel SE, Gracey EG, Lampe JN. Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach. Chem Res Toxicol. 2023 10 16; 36(10):1631-1642.
Score: 0.190
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Liu J, Kandel SE, Lampe JN, Scott EE. Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate. J Biol Chem. 2023 08; 299(8):104993.
Score: 0.187
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Work HM, Kandel SE, Lampe JN. Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening. Sci Rep. 2021 09 30; 11(1):19443.
Score: 0.165
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Hvizdak M, Kandel SE, Work HM, Gracey EG, McCullough RL, Lampe JN. Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement. J Inorg Biochem. 2023 03; 240:112120.
Score: 0.045
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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