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Connection

Margaret Wierman to Gonadotropin-Releasing Hormone

This is a "connection" page, showing publications Margaret Wierman has written about Gonadotropin-Releasing Hormone.

 
Connection Strength
  
 
 
5.470
  
  1. Salian-Mehta S, Xu M, McKinsey TA, Tobet S, Wierman ME. Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement. J Biol Chem. 2015 May 29; 290(22):14045-56.
    View in: PubMed
    Score: 0.442
  2. Salian-Mehta S, Xu M, Wierman ME. AXL and MET crosstalk to promote gonadotropin releasing hormone (GnRH) neuronal cell migration and survival. Mol Cell Endocrinol. 2013 Jul 15; 374(1-2):92-100.
    View in: PubMed
    Score: 0.386
  3. Wierman ME, Xu M, Pierce A, Bliesner B, Bliss SP, Roberson MS. Extracellular signal-regulated kinase 1 and 2 are not required for GnRH neuron development and normal female reproductive axis function in mice. Neuroendocrinology. 2012; 95(4):289-96.
    View in: PubMed
    Score: 0.351
  4. Wierman ME, Kiseljak-Vassiliades K, Tobet S. Gonadotropin-releasing hormone (GnRH) neuron migration: initiation, maintenance and cessation as critical steps to ensure normal reproductive function. Front Neuroendocrinol. 2011 Jan; 32(1):43-52.
    View in: PubMed
    Score: 0.319
  5. Pierce A, Bliesner B, Xu M, Nielsen-Preiss S, Lemke G, Tobet S, Wierman ME. Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Mol Endocrinol. 2008 Nov; 22(11):2481-95.
    View in: PubMed
    Score: 0.280
  6. Rothman MS, Wierman ME. The role of gonadotropin releasing hormone in normal and pathologic endocrine processes. Curr Opin Endocrinol Diabetes Obes. 2007 Aug; 14(4):306-10.
    View in: PubMed
    Score: 0.259
  7. Nielsen-Preiss SM, Allen MP, Xu M, Linseman DA, Pawlowski JE, Bouchard RJ, Varnum BC, Heidenreich KA, Wierman ME. Adhesion-related kinase induction of migration requires phosphatidylinositol-3-kinase and ras stimulation of rac activity in immortalized gonadotropin-releasing hormone neuronal cells. Endocrinology. 2007 Jun; 148(6):2806-14.
    View in: PubMed
    Score: 0.252
  8. Wierman ME, Pawlowski JE, Allen MP, Xu M, Linseman DA, Nielsen-Preiss S. Molecular mechanisms of gonadotropin-releasing hormone neuronal migration. Trends Endocrinol Metab. 2004 Apr; 15(3):96-102.
    View in: PubMed
    Score: 0.206
  9. Allen MP, Xu M, Linseman DA, Pawlowski JE, Bokoch GM, Heidenreich KA, Wierman ME. Adhesion-related kinase repression of gonadotropin-releasing hormone gene expression requires Rac activation of the extracellular signal-regulated kinase pathway. J Biol Chem. 2002 Oct 11; 277(41):38133-40.
    View in: PubMed
    Score: 0.183
  10. Allen MP, Linseman DA, Udo H, Xu M, Schaack JB, Varnum B, Kandel ER, Heidenreich KA, Wierman ME. Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase. Mol Cell Biol. 2002 Jan; 22(2):599-613.
    View in: PubMed
    Score: 0.176
  11. Allen MP, Xu M, Zeng C, Tobet SA, Wierman ME. Myocyte enhancer factors-2B and -2C are required for adhesion related kinase repression of neuronal gonadotropin releasing hormone gene expression. J Biol Chem. 2000 Dec 15; 275(50):39662-70.
    View in: PubMed
    Score: 0.164
  12. Davis EE, Balasubramanian R, Kupchinsky ZA, Keefe DL, Plummer L, Khan K, Meczekalski B, Heath KE, Lopez-Gonzalez V, Ballesta-Martinez MJ, Margabanthu G, Price S, Greening J, Brauner R, Valenzuela I, Cusco I, Fernandez-Alvarez P, Wierman ME, Li T, Lage K, Barroso PS, Chan YM, Crowley WF, Katsanis N. TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci. Hum Mol Genet. 2020 08 11; 29(14):2435-2450.
    View in: PubMed
    Score: 0.160
  13. Allen MP, Zeng C, Schneider K, Xiong X, Meintzer MK, Bellosta P, Basilico C, Varnum B, Heidenreich KA, Wierman ME. Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt. Mol Endocrinol. 1999 Feb; 13(2):191-201.
    View in: PubMed
    Score: 0.144
  14. Fang Z, Xiong X, James A, Gordon DF, Wierman ME. Identification of novel factors that regulate GnRH gene expression and neuronal migration. Endocrinology. 1998 Aug; 139(8):3654-7.
    View in: PubMed
    Score: 0.139
  15. Gavin KM, Shea KL, Gibbons E, Wolfe P, Schwartz RS, Wierman ME, Kohrt WM. Gonadotropin-releasing hormone agonist in premenopausal women does not alter hypothalamic-pituitary-adrenal axis response to corticotropin-releasing hormone. Am J Physiol Endocrinol Metab. 2018 08 01; 315(2):E316-E325.
    View in: PubMed
    Score: 0.136
  16. Wierman ME, Xiong X, Kepa JK, Spaulding AJ, Jacobsen BM, Fang Z, Nilaver G, Ojeda SR. Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: a regulatory mechanism of phenotype expression? Mol Cell Biol. 1997 Mar; 17(3):1652-65.
    View in: PubMed
    Score: 0.126
  17. Kepa JK, Spaulding AJ, Jacobsen BM, Fang Z, Xiong X, Radovick S, Wierman ME. Structure of the distal human gonadotropin releasing hormone (hGnrh) gene promoter and functional analysis in Gt1-7 neuronal cells. Nucleic Acids Res. 1996 Sep 15; 24(18):3614-20.
    View in: PubMed
    Score: 0.122
  18. Kepa JK, Jacobsen BM, Boen EA, Prendergast P, Edwards DP, Takimoto G, Wierman ME. Direct binding of progesterone receptor to nonconsensus DNA sequences represses rat GnRH. Mol Cell Endocrinol. 1996 Mar 01; 117(1):27-39.
    View in: PubMed
    Score: 0.117
  19. Bruder JM, Spaulding AJ, Wierman ME. Phorbol ester inhibition of rat gonadotropin-releasing hormone promoter activity: role of Fos and Jun in the repression of transcription. Mol Endocrinol. 1996 Jan; 10(1):35-44.
    View in: PubMed
    Score: 0.116
  20. Shea KL, Gavin KM, Melanson EL, Gibbons E, Stavros A, Wolfe P, Kittelson JM, Vondracek SF, Schwartz RS, Wierman ME, Kohrt WM. Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment. Menopause. 2015 Oct; 22(10):1045-52.
    View in: PubMed
    Score: 0.114
  21. Melanson EL, Gavin KM, Shea KL, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Regulation of energy expenditure by estradiol in premenopausal women. J Appl Physiol (1985). 2015 Nov 01; 119(9):975-81.
    View in: PubMed
    Score: 0.114
  22. Wierman ME, Bruder JM, Kepa JK. Regulation of gonadotropin-releasing hormone (GnRH) gene expression in hypothalamic neuronal cells. Cell Mol Neurobiol. 1995 Feb; 15(1):79-88.
    View in: PubMed
    Score: 0.109
  23. Bruder JM, Samuels MH, Bremner WJ, Ridgway EC, Wierman ME. Hypothyroidism-induced macroorchidism: use of a gonadotropin-releasing hormone agonist to understand its mechanism and augment adult stature. J Clin Endocrinol Metab. 1995 Jan; 80(1):11-6.
    View in: PubMed
    Score: 0.108
  24. Bruder JM, Wierman ME. Evidence for transcriptional inhibition of GnRH gene expression by phorbol ester at a proximal promoter region. Mol Cell Endocrinol. 1994 Mar; 99(2):177-82.
    View in: PubMed
    Score: 0.102
  25. Bruder JM, Krebs WD, Nett TM, Wierman ME. Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression. Endocrinology. 1992 Dec; 131(6):2552-8.
    View in: PubMed
    Score: 0.094
  26. Wierman ME, Kepa JK, Sun W, Gordon DF, Wood WM. Estrogen negatively regulates rat gonadotropin releasing hormone (rGnRH) promoter activity in transfected placental cells. Mol Cell Endocrinol. 1992 Jul; 86(1-2):1-10.
    View in: PubMed
    Score: 0.091
  27. Kepa JK, Wang C, Neeley CI, Raynolds MV, Gordon DF, Wood WM, Wierman ME. Structure of the rat gonadotropin releasing hormone (rGnRH) gene promoter and functional analysis in hypothalamic cells. Nucleic Acids Res. 1992 Mar 25; 20(6):1393-9.
    View in: PubMed
    Score: 0.089
  28. Pierce A, Xu M, Bliesner B, Liu Z, Richards J, Tobet S, Wierman ME. Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice. Mol Cell Endocrinol. 2011 Jun 06; 339(1-2):151-8.
    View in: PubMed
    Score: 0.084
  29. Wierman ME, Wang C. Androgen selectively stimulates follicle-stimulating hormone-beta mRNA levels after gonadotropin-releasing hormone antagonist administration. Biol Reprod. 1990 Mar; 42(3):563-71.
    View in: PubMed
    Score: 0.078
  30. Wierman ME, Rivier JE, Wang C. Gonadotropin-releasing hormone-dependent regulation of gonadotropin subunit messenger ribonucleic acid levels in the rat. Endocrinology. 1989 Jan; 124(1):272-8.
    View in: PubMed
    Score: 0.072
  31. Schwarting GA, Wierman ME, Tobet SA. Gonadotropin-releasing hormone neuronal migration. Semin Reprod Med. 2007 Sep; 25(5):305-12.
    View in: PubMed
    Score: 0.065
  32. Wierman ME, Beardsworth DE, Crawford JD, Crigler JF, Mansfield MJ, Bode HH, Boepple PA, Kushner DC, Crowley WF. Adrenarche and skeletal maturation during luteinizing hormone releasing hormone analogue suppression of gonadarche. J Clin Invest. 1986 Jan; 77(1):121-6.
    View in: PubMed
    Score: 0.058
  33. Harrison GS, Wierman ME, Nett TM, Glode LM. Gonadotropin-releasing hormone and its receptor in normal and malignant cells. Endocr Relat Cancer. 2004 Dec; 11(4):725-48.
    View in: PubMed
    Score: 0.054
  34. Petroff BK, Croutch CR, Hunter DM, Wierman ME, Gao X. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) stimulates gonadotropin secretion in the immature female Sprague-Dawley rat through a pentobarbital- and estradiol-sensitive mechanism but does not alter gonadotropin-releasing hormone (GnRH) secretion by immortalized GnRH neurons in vitro. Biol Reprod. 2003 Jun; 68(6):2100-6.
    View in: PubMed
    Score: 0.047
  35. Melanson EL, Lyden K, Gibbons E, Gavin KM, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Influence of Estradiol Status on Physical Activity in Premenopausal Women. Med Sci Sports Exerc. 2018 08; 50(8):1704-1709.
    View in: PubMed
    Score: 0.035
  36. Martin K, Santoro N, Hall J, Filicori M, Wierman M, Crowley WF. Clinical review 15: Management of ovulatory disorders with pulsatile gonadotropin-releasing hormone. J Clin Endocrinol Metab. 1990 Nov; 71(5):1081A-1081G.
    View in: PubMed
    Score: 0.020
  37. Hall DA, Crowley WF, Wierman ME, Simeone JF, McCarthy KA. Sonographic monitoring of LHRH analogue therapy in idiopathic precocious puberty in young girls. J Clin Ultrasound. 1986 Jun; 14(5):331-8.
    View in: PubMed
    Score: 0.015
  38. Boepple PA, Mansfield MJ, Wierman ME, Rudlin CR, Bode HH, Crigler JF, Crawford JD, Crowley WF. Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. Endocr Rev. 1986 Feb; 7(1):24-33.
    View in: PubMed
    Score: 0.015
  39. Santoro N, Wierman ME, Filicori M, Waldstreicher J, Crowley WF. Intravenous administration of pulsatile gonadotropin-releasing hormone in hypothalamic amenorrhea: effects of dosage. J Clin Endocrinol Metab. 1986 Jan; 62(1):109-16.
    View in: PubMed
    Score: 0.015
  40. Wierman ME, Beardsworth DE, Mansfield MJ, Badger TM, Crawford JD, Crigler JF, Bode HH, Loughlin JS, Kushner DC, Scully RE, et al. Puberty without gonadotropins. A unique mechanism of sexual development. N Engl J Med. 1985 Jan 10; 312(2):65-72.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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