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Connection

Margaret Wierman to Animals

This is a "connection" page, showing publications Margaret Wierman has written about Animals.

 
Connection Strength
  
 
 
0.714
  
  1. Santoro N, Wierman ME. Do Women Need Androgens Like a Fish Needs a Bicycle? A Review of the Literature and Clinical Guidelines. Clin Obstet Gynecol. 2021 12 01; 64(4):784-792.
    View in: PubMed
    Score: 0.044
  2. Kohrt WM, Wierman ME. Preventing Fat Gain by Blocking Follicle-Stimulating Hormone. N Engl J Med. 2017 Jul 20; 377(3):293-295.
    View in: PubMed
    Score: 0.033
  3. Xiong W, Matheson CJ, Xu M, Backos DS, Mills TS, Salian-Mehta S, Kiseljak-Vassiliades K, Reigan P, Wierman ME. Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary Tumors. Mol Cancer Ther. 2016 Mar; 15(3):412-20.
    View in: PubMed
    Score: 0.029
  4. Salian-Mehta S, Xu M, McKinsey TA, Tobet S, Wierman ME. Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement. J Biol Chem. 2015 May 29; 290(22):14045-56.
    View in: PubMed
    Score: 0.028
  5. Wierman ME, Auchus RJ, Haisenleder DJ, Hall JE, Handelsman D, Hankinson S, Rosner W, Singh RJ, Sluss PM, Stanczyk FZ. Editorial: the new instructions to authors for the reporting of steroid hormone measurements. Mol Endocrinol. 2014 Dec; 28(12):1917.
    View in: PubMed
    Score: 0.027
  6. Salian-Mehta S, Xu M, Pierce A, Bliesner B, Tobet S, Wierman ME. Loss of Growth arrest specific gene 6 (Gas6) results in altered GnRH neuron migration, delayed vaginal opening and sexual maturation in mice. Mol Cell Endocrinol. 2014 Aug 05; 393(1-2):164-70.
    View in: PubMed
    Score: 0.027
  7. Salian-Mehta S, Xu M, Knox AJ, Plummer L, Slavov D, Taylor M, Bevers S, Hodges RS, Crowley WF, Wierman ME. Functional consequences of AXL sequence variants in hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2014 Apr; 99(4):1452-60.
    View in: PubMed
    Score: 0.026
  8. Salian-Mehta S, Xu M, Wierman ME. AXL and MET crosstalk to promote gonadotropin releasing hormone (GnRH) neuronal cell migration and survival. Mol Cell Endocrinol. 2013 Jul 15; 374(1-2):92-100.
    View in: PubMed
    Score: 0.024
  9. Xu M, Knox AJ, Michaelis KA, Kiseljak-Vassiliades K, Kleinschmidt-DeMasters BK, Lillehei KO, Wierman ME. Reprimo (RPRM) is a novel tumor suppressor in pituitary tumors and regulates survival, proliferation, and tumorigenicity. Endocrinology. 2012 Jul; 153(7):2963-73.
    View in: PubMed
    Score: 0.023
  10. Kiseljak-Vassiliades K, Shafi S, Kerr JM, Phang TL, Kleinschmidt-DeMasters BK, Wierman ME. Clinical implications of growth hormone-secreting tumor subtypes. Endocrine. 2012 Aug; 42(1):18-28.
    View in: PubMed
    Score: 0.023
  11. Wierman ME, Xu M, Pierce A, Bliesner B, Bliss SP, Roberson MS. Extracellular signal-regulated kinase 1 and 2 are not required for GnRH neuron development and normal female reproductive axis function in mice. Neuroendocrinology. 2012; 95(4):289-96.
    View in: PubMed
    Score: 0.022
  12. Michaelis KA, Knox AJ, Xu M, Kiseljak-Vassiliades K, Edwards MG, Geraci M, Kleinschmidt-DeMasters BK, Lillehei KO, Wierman ME. Identification of growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a novel tumor suppressor in pituitary gonadotrope tumors. Endocrinology. 2011 Oct; 152(10):3603-13.
    View in: PubMed
    Score: 0.022
  13. Pierce A, Xu M, Bliesner B, Liu Z, Richards J, Tobet S, Wierman ME. Hypothalamic but not pituitary or ovarian defects underlie the reproductive abnormalities in Axl/Tyro3 null mice. Mol Cell Endocrinol. 2011 Jun 06; 339(1-2):151-8.
    View in: PubMed
    Score: 0.021
  14. Wierman ME, Kiseljak-Vassiliades K, Tobet S. Gonadotropin-releasing hormone (GnRH) neuron migration: initiation, maintenance and cessation as critical steps to ensure normal reproductive function. Front Neuroendocrinol. 2011 Jan; 32(1):43-52.
    View in: PubMed
    Score: 0.020
  15. Xu M, Shorts-Cary L, Knox AJ, Kleinsmidt-DeMasters B, Lillehei K, Wierman ME. Epidermal growth factor receptor pathway substrate 8 is overexpressed in human pituitary tumors: role in proliferation and survival. Endocrinology. 2009 May; 150(5):2064-71.
    View in: PubMed
    Score: 0.018
  16. Pierce A, Bliesner B, Xu M, Nielsen-Preiss S, Lemke G, Tobet S, Wierman ME. Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Mol Endocrinol. 2008 Nov; 22(11):2481-95.
    View in: PubMed
    Score: 0.018
  17. Wierman ME. Sex steroid effects at target tissues: mechanisms of action. Adv Physiol Educ. 2007 Mar; 31(1):26-33.
    View in: PubMed
    Score: 0.016
  18. Nielsen-Preiss SM, Allen MP, Xu M, Linseman DA, Pawlowski JE, Bouchard RJ, Varnum BC, Heidenreich KA, Wierman ME. Adhesion-related kinase induction of migration requires phosphatidylinositol-3-kinase and ras stimulation of rac activity in immortalized gonadotropin-releasing hormone neuronal cells. Endocrinology. 2007 Jun; 148(6):2806-14.
    View in: PubMed
    Score: 0.016
  19. Rothman MS, Arciniegas DB, Filley CM, Wierman ME. The neuroendocrine effects of traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2007; 19(4):363-72.
    View in: PubMed
    Score: 0.016
  20. Shorts-Cary L, Xu M, Ertel J, Kleinschmidt-Demasters BK, Lillehei K, Matsuoka I, Nielsen-Preiss S, Wierman ME. Bone morphogenetic protein and retinoic acid-inducible neural specific protein-3 is expressed in gonadotrope cell pituitary adenomas and induces proliferation, migration, and invasion. Endocrinology. 2007 Mar; 148(3):967-75.
    View in: PubMed
    Score: 0.016
  21. Wierman ME, Pawlowski JE, Allen MP, Xu M, Linseman DA, Nielsen-Preiss S. Molecular mechanisms of gonadotropin-releasing hormone neuronal migration. Trends Endocrinol Metab. 2004 Apr; 15(3):96-102.
    View in: PubMed
    Score: 0.013
  22. Ruggiero C, Tamburello M, Rossini E, Zini S, Durand N, Cantini G, Cioppi F, Hantel C, Kiseljak-Vassiliades K, Wierman ME, Landwehr LS, Weigand I, Kurlbaum M, Zizioli D, Turtoi A, Yang S, Berruti A, Luconi M, Sigala S, Lalli E. FSCN1 as a new druggable target in adrenocortical carcinoma. Int J Cancer. 2023 07 01; 153(1):210-223.
    View in: PubMed
    Score: 0.012
  23. Allen MP, Xu M, Linseman DA, Pawlowski JE, Bokoch GM, Heidenreich KA, Wierman ME. Adhesion-related kinase repression of gonadotropin-releasing hormone gene expression requires Rac activation of the extracellular signal-regulated kinase pathway. J Biol Chem. 2002 Oct 11; 277(41):38133-40.
    View in: PubMed
    Score: 0.012
  24. Pawlowski JE, Ertel JR, Allen MP, Xu M, Butler C, Wilson EM, Wierman ME. Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem. 2002 Jun 07; 277(23):20702-10.
    View in: PubMed
    Score: 0.011
  25. Allen MP, Linseman DA, Udo H, Xu M, Schaack JB, Varnum B, Kandel ER, Heidenreich KA, Wierman ME. Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase. Mol Cell Biol. 2002 Jan; 22(2):599-613.
    View in: PubMed
    Score: 0.011
  26. Allen MP, Xu M, Zeng C, Tobet SA, Wierman ME. Myocyte enhancer factors-2B and -2C are required for adhesion related kinase repression of neuronal gonadotropin releasing hormone gene expression. J Biol Chem. 2000 Dec 15; 275(50):39662-70.
    View in: PubMed
    Score: 0.010
  27. Davis EE, Balasubramanian R, Kupchinsky ZA, Keefe DL, Plummer L, Khan K, Meczekalski B, Heath KE, Lopez-Gonzalez V, Ballesta-Martinez MJ, Margabanthu G, Price S, Greening J, Brauner R, Valenzuela I, Cusco I, Fernandez-Alvarez P, Wierman ME, Li T, Lage K, Barroso PS, Chan YM, Crowley WF, Katsanis N. TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci. Hum Mol Genet. 2020 08 11; 29(14):2435-2450.
    View in: PubMed
    Score: 0.010
  28. Kar A, Wierman ME, Kiseljak-Vassiliades K. Update on in-vivo preclinical research models in adrenocortical carcinoma. Curr Opin Endocrinol Diabetes Obes. 2020 06; 27(3):170-176.
    View in: PubMed
    Score: 0.010
  29. Lang J, Capasso A, Jordan KR, French JD, Kar A, Bagby SM, Barbee J, Yacob BW, Head LS, Tompkins KD, Freed BM, Somerset H, Clark TJ, Pitts TM, Messersmith WA, Eckhardt SG, Wierman ME, Leong S, Kiseljak-Vassiliades K. Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment. J Clin Endocrinol Metab. 2020 01 01; 105(1).
    View in: PubMed
    Score: 0.010
  30. Kar A, Zhang Y, Yacob BW, Saeed J, Tompkins KD, Bagby SM, Pitts TM, Somerset H, Leong S, Wierman ME, Kiseljak-Vassiliades K. Targeting PDZ-binding kinase is anti-tumorigenic in novel preclinical models of ACC. Endocr Relat Cancer. 2019 10; 26(10):765-778.
    View in: PubMed
    Score: 0.010
  31. Grossmann M, Wierman ME, Angus P, Handelsman DJ. Reproductive Endocrinology of Nonalcoholic Fatty Liver Disease. Endocr Rev. 2019 04 01; 40(2):417-446.
    View in: PubMed
    Score: 0.009
  32. Allen MP, Zeng C, Schneider K, Xiong X, Meintzer MK, Bellosta P, Basilico C, Varnum B, Heidenreich KA, Wierman ME. Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt. Mol Endocrinol. 1999 Feb; 13(2):191-201.
    View in: PubMed
    Score: 0.009
  33. Roof AK, Jirawatnotai S, Trudeau T, Kuzyk C, Wierman ME, Kiyokawa H, Gutierrez-Hartmann A. The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine. Endocrinology. 2018 06 01; 159(6):2421-2434.
    View in: PubMed
    Score: 0.009
  34. Wierman ME, Xiong X, Kepa JK, Spaulding AJ, Jacobsen BM, Fang Z, Nilaver G, Ojeda SR. Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: a regulatory mechanism of phenotype expression? Mol Cell Biol. 1997 Mar; 17(3):1652-65.
    View in: PubMed
    Score: 0.008
  35. Kepa JK, Spaulding AJ, Jacobsen BM, Fang Z, Xiong X, Radovick S, Wierman ME. Structure of the distal human gonadotropin releasing hormone (hGnrh) gene promoter and functional analysis in Gt1-7 neuronal cells. Nucleic Acids Res. 1996 Sep 15; 24(18):3614-20.
    View in: PubMed
    Score: 0.008
  36. Kepa JK, Jacobsen BM, Boen EA, Prendergast P, Edwards DP, Takimoto G, Wierman ME. Direct binding of progesterone receptor to nonconsensus DNA sequences represses rat GnRH. Mol Cell Endocrinol. 1996 Mar 01; 117(1):27-39.
    View in: PubMed
    Score: 0.007
  37. Bruder JM, Spaulding AJ, Wierman ME. Phorbol ester inhibition of rat gonadotropin-releasing hormone promoter activity: role of Fos and Jun in the repression of transcription. Mol Endocrinol. 1996 Jan; 10(1):35-44.
    View in: PubMed
    Score: 0.007
  38. Wierman ME, Bruder JM, Kepa JK. Regulation of gonadotropin-releasing hormone (GnRH) gene expression in hypothalamic neuronal cells. Cell Mol Neurobiol. 1995 Feb; 15(1):79-88.
    View in: PubMed
    Score: 0.007
  39. Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox AJ, Asada Y, Wierman ME, Hirata K, Rikitake Y. Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation. PLoS One. 2014; 9(9):e107236.
    View in: PubMed
    Score: 0.007
  40. Bruder JM, Wierman ME. Evidence for transcriptional inhibition of GnRH gene expression by phorbol ester at a proximal promoter region. Mol Cell Endocrinol. 1994 Mar; 99(2):177-82.
    View in: PubMed
    Score: 0.006
  41. Bruder JM, Krebs WD, Nett TM, Wierman ME. Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression. Endocrinology. 1992 Dec; 131(6):2552-8.
    View in: PubMed
    Score: 0.006
  42. Wierman ME, Kepa JK, Sun W, Gordon DF, Wood WM. Estrogen negatively regulates rat gonadotropin releasing hormone (rGnRH) promoter activity in transfected placental cells. Mol Cell Endocrinol. 1992 Jul; 86(1-2):1-10.
    View in: PubMed
    Score: 0.006
  43. Kepa JK, Wang C, Neeley CI, Raynolds MV, Gordon DF, Wood WM, Wierman ME. Structure of the rat gonadotropin releasing hormone (rGnRH) gene promoter and functional analysis in hypothalamic cells. Nucleic Acids Res. 1992 Mar 25; 20(6):1393-9.
    View in: PubMed
    Score: 0.006
  44. Wierman ME, Gharib SD, Wang C, LaRovere JM, Badger TM, Chin WW. Divergent regulation of gonadotropin subunit mRNA levels by androgens in the female rat. Biol Reprod. 1990 Aug; 43(2):191-5.
    View in: PubMed
    Score: 0.005
  45. Wierman ME, Wang C. Androgen selectively stimulates follicle-stimulating hormone-beta mRNA levels after gonadotropin-releasing hormone antagonist administration. Biol Reprod. 1990 Mar; 42(3):563-71.
    View in: PubMed
    Score: 0.005
  46. Wierman ME, Rivier JE, Wang C. Gonadotropin-releasing hormone-dependent regulation of gonadotropin subunit messenger ribonucleic acid levels in the rat. Endocrinology. 1989 Jan; 124(1):272-8.
    View in: PubMed
    Score: 0.005
  47. Wierman ME, Gharib SD, Chin WW. The structure and regulation of the pituitary gonadotrophin subunit genes. Baillieres Clin Endocrinol Metab. 1988 Nov; 2(4):869-89.
    View in: PubMed
    Score: 0.004
  48. Wierman ME, Gharib SD, LaRovere JM, Badger TM, Chin WW. Selective failure of androgens to regulate follicle stimulating hormone beta messenger ribonucleic acid levels in the male rat. Mol Endocrinol. 1988 Jun; 2(6):492-8.
    View in: PubMed
    Score: 0.004
  49. Schwarting GA, Wierman ME, Tobet SA. Gonadotropin-releasing hormone neuronal migration. Semin Reprod Med. 2007 Sep; 25(5):305-12.
    View in: PubMed
    Score: 0.004
  50. Harrison GS, Wierman ME, Nett TM, Glode LM. Gonadotropin-releasing hormone and its receptor in normal and malignant cells. Endocr Relat Cancer. 2004 Dec; 11(4):725-48.
    View in: PubMed
    Score: 0.003
  51. Petroff BK, Croutch CR, Hunter DM, Wierman ME, Gao X. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) stimulates gonadotropin secretion in the immature female Sprague-Dawley rat through a pentobarbital- and estradiol-sensitive mechanism but does not alter gonadotropin-releasing hormone (GnRH) secretion by immortalized GnRH neurons in vitro. Biol Reprod. 2003 Jun; 68(6):2100-6.
    View in: PubMed
    Score: 0.003
  52. Childs GV, Unabia G, Wierman ME, Gharib SD, Chin WW. Castration induces time-dependent changes in the follicle-stimulating hormone beta-subunit messenger ribonucleic acid-containing gonadotrope cell population. Endocrinology. 1990 Apr; 126(4):2205-13.
    View in: PubMed
    Score: 0.001
  53. Gharib SD, Wierman ME, Shupnik MA, Chin WW. Molecular biology of the pituitary gonadotropins. Endocr Rev. 1990 Feb; 11(1):177-99.
    View in: PubMed
    Score: 0.001
  54. Gharib SD, Roy A, Wierman ME, Chin WW. Isolation and characterization of the gene encoding the beta-subunit of rat follicle-stimulating hormone. DNA. 1989 Jun; 8(5):339-49.
    View in: PubMed
    Score: 0.001
  55. Samuels MH, Wierman ME, Wang C, Ridgway EC. The effect of altered thyroid status on pituitary hormone messenger ribonucleic acid concentrations in the rat. Endocrinology. 1989 May; 124(5):2277-82.
    View in: PubMed
    Score: 0.001
  56. Childs GV, Lloyd JM, Unabia G, Gharib SD, Wierman ME, Chin WW. Detection of luteinizing hormone beta messenger ribonucleic acid (RNA) in individual gonadotropes after castration: use of a new in situ hybridization method with a photobiotinylated complementary RNA probe. Mol Endocrinol. 1987 Dec; 1(12):926-32.
    View in: PubMed
    Score: 0.001
  57. Gharib SD, Wierman ME, Badger TM, Chin WW. Sex steroid hormone regulation of follicle-stimulating hormone subunit messenger ribonucleic acid (mRNA) levels in the rat. J Clin Invest. 1987 Aug; 80(2):294-9.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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