 Connection
Daniel Ambruso to Neutrophils
This is a "connection" page, showing publications Daniel Ambruso has written about Neutrophils.
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Connection Strength |
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4.635 |
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Ambruso DR, Briones NJ, Tran AD, Sanford B, Childs C, Katz BZ, Ellison M, Johnston RB, Jones KL. Interferon-gamma 1b-induced gene expression alters neutrophil function in patients with chronic granulomatous disease. PLoS One. 2025; 20(9):e0331657.
Score: 0.614
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Ambruso DR, Briones NJ, Baroffio AF, Murphy JR, Tran AD, Gowan K, Sanford B, Ellison M, Jones KL. In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype. PLoS One. 2022; 17(2):e0263370.
Score: 0.479
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McKinney C, Ellison M, Briones NJ, Baroffio A, Murphy J, Tran AD, Reisz JA, D'Alessandro A, Ambruso DR. Metabolic abnormalities in G6PC3-deficient human neutrophils result in severe functional defects. Blood Adv. 2020 12 08; 4(23):5888-5901.
Score: 0.442
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Ellison MA, Gearheart CM, Porter CC, Ambruso DR. IFN-? alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils. PLoS One. 2017; 12(10):e0185956.
Score: 0.355
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Ambruso DR, Ellison MA, Thurman GW, Leto TL. Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity. Biochim Biophys Acta. 2012 Feb; 1823(2):306-15.
Score: 0.237
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Alsultan A, Sokol RJ, Lovell MA, Thurman G, Ambruso DR. Long term G-CSF-induced remission of ulcerative colitis-like inflammatory bowel disease in a patient with glycogen storage disease Ib and evaluation of associated neutrophil function. Pediatr Blood Cancer. 2010 Dec 15; 55(7):1410-3.
Score: 0.221
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Ambruso DR, Thurman G, Tran K, Marschner S, Gathof B, Janetzko K, Goodrich RP. Generation of neutrophil priming activity by cell-containing blood components treated with pathogen reduction technology and stored in platelet additive solutions. Transfusion. 2011 Jun; 51(6):1220-7.
Score: 0.221
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Chudgar UH, Thurman GW, Ambruso DR. Oxidase activity in cord blood neutrophils: a balance between increased membrane associated cytochrome b558 and deficient cytosolic components. Pediatr Blood Cancer. 2005 Sep; 45(3):311-7.
Score: 0.153
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Anderson MS, Knall C, Thurman G, Mann D, Cusack N, Johnson GL, Ambruso DR. CP-64131, an aminobenzazepine with cytokine-like properties, stimulates human neutrophil functions through the p38-MAPK pathway. J Leukoc Biol. 2004 Aug; 76(2):477-83.
Score: 0.140
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Ambruso DR, Cusack N, Thurman G. NADPH oxidase activity of neutrophil specific granules: requirements for cytosolic components and evidence of assembly during cell activation. Mol Genet Metab. 2004 Apr; 81(4):313-21.
Score: 0.139
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Zimbelman J, Thurman G, Leavey PJ, Ellison MC, Ambruso DR. In vivo treatment with granulocyte colony-stimulating factor does not delay apoptosis in human neutrophils by increasing the expression of the vacuolar proton ATPase. J Investig Med. 2002 Jan; 50(1):33-7.
Score: 0.119
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Kurkchubasche AG, Panepinto JA, Tracy TF, Thurman GW, Ambruso DR. Clinical features of a human Rac2 mutation: a complex neutrophil dysfunction disease. J Pediatr. 2001 Jul; 139(1):141-7.
Score: 0.115
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Ambruso DR, Knall C, Abell AN, Panepinto J, Kurkchubasche A, Thurman G, Gonzalez-Aller C, Hiester A, deBoer M, Harbeck RJ, Oyer R, Johnson GL, Roos D. Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4654-9.
Score: 0.106
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Leavey PJ, Thurman G, Ambruso DR. Functional characteristics of neutrophils collected and stored after administration of G-CSF. Transfusion. 2000 Apr; 40(4):414-9.
Score: 0.105
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Leavey PJ, Sellins KS, Thurman G, Elzi D, Hiester A, Silliman CC, Zerbe G, Cohen JJ, Ambruso DR. In vivo treatment with granulocyte colony-stimulating factor results in divergent effects on neutrophil functions measured in vitro. Blood. 1998 Dec 01; 92(11):4366-74.
Score: 0.096
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Leavey PJ, Thurman G, Gonzalez-Aller C, Zerbe G, Ambruso DR. The effects of stem cell factor and granulocyte colony stimulating factor therapy on the activity of the neutrophil NADPH oxidase enzyme system. J Investig Med. 1998 Apr; 46(4):121-6.
Score: 0.092
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Rosenthal J, Thurman GW, Cusack N, Peterson VM, Malech HL, Ambruso DR. Neutrophils from patients after burn injury express a deficiency of the oxidase components p47-phox and p67-phox. Blood. 1996 Dec 01; 88(11):4321-9.
Score: 0.084
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Silliman CC, Cusack NA, Swanson NJ, Ghaffarifar S, Ambruso DR. Platelets and neutrophils from healthy term neonates exhibit increased levels of immunoglobulins. Pediatr Res. 1995 Dec; 38(6):993-7.
Score: 0.078
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Cancelas JA, Padmanabhan A, Le T, Ambruso DR, Rugg N, Worsham DN, Pinkard SL, Graminske S, Buck J, Goldberg J, Bill J. Spectra Optia granulocyte apheresis collections result in higher collection efficiency of viable, functional neutrophils in a randomized, crossover, multicenter trial. Transfusion. 2015 Apr; 55(4):748-55.
Score: 0.073
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Silliman CC, Clay KL, Thurman GW, Johnson CA, Ambruso DR. Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase. J Lab Clin Med. 1994 Nov; 124(5):684-94.
Score: 0.072
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Ambruso DR. Peroxiredoxin-6 and NADPH oxidase activity. Methods Enzymol. 2013; 527:145-67.
Score: 0.064
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Silliman CC, Thurman GW, Ambruso DR. Stored blood components contain agents that prime the neutrophil NADPH oxidase through the platelet-activating-factor receptor. Vox Sang. 1992; 63(2):133-6.
Score: 0.059
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Pitman JM, Thurman GW, Anderson BO, Ketch LL, Hartford CE, Harken AH, Ambruso DR. WEB2170, a specific platelet-activating factor antagonist, attenuates neutrophil priming by human serum after clinical burn injury: the 1991 Moyer Award. J Burn Care Rehabil. 1991 Sep-Oct; 12(5):411-9.
Score: 0.058
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Ambruso DR, Bolscher BG, Stokman PM, Verhoeven AJ, Roos D. Assembly and activation of the NADPH:O2 oxidoreductase in human neutrophils after stimulation with phorbol myristate acetate. J Biol Chem. 1990 Jan 15; 265(2):924-30.
Score: 0.052
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Ambruso DR, Stork LC, Gibson BE, Thurman GW. Increased activity of the respiratory burst in cord blood neutrophils: kinetics of the NADPH oxidase enzyme system in subcellular fractions. Pediatr Res. 1987 Feb; 21(2):205-10.
Score: 0.042
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Silliman CC, Curtis BR, Kopko PM, Khan SY, Kelher MR, Schuller RM, Sannoh B, Ambruso DR. Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model. Blood. 2007 Feb 15; 109(4):1752-5.
Score: 0.041
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Ambruso DR, Bentwood B, Henson PM, Johnston RB. Oxidative metabolism of cord blood neutrophils: relationship to content and degranulation of cytoplasmic granules. Pediatr Res. 1984 Nov; 18(11):1148-53.
Score: 0.036
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Ambruso DR, Sasada M, Nishiyama H, Kubo A, Komiyama A, Allen RH. Defective bactericidal activity and absence of specific granules in neutrophils from a patient with recurrent bacterial infections. J Clin Immunol. 1984 Jan; 4(1):23-30.
Score: 0.034
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Kelher MR, Ambruso DR, Elzi DJ, Anderson SM, Paterson AJ, Thurman GW, Silliman CC. Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils. Cell Calcium. 2003 Dec; 34(6):445-55.
Score: 0.034
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Silliman CC, Elzi DJ, Ambruso DR, Musters RJ, Hamiel C, Harbeck RJ, Paterson AJ, Bjornsen AJ, Wyman TH, Kelher M, England KM, McLaughlin-Malaxecheberria N, Barnett CC, Aiboshi J, Bannerjee A. Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium. J Leukoc Biol. 2003 Apr; 73(4):511-24.
Score: 0.032
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Silliman CC, Boshkov LK, Mehdizadehkashi Z, Elzi DJ, Dickey WO, Podlosky L, Clarke G, Ambruso DR. Transfusion-related acute lung injury: epidemiology and a prospective analysis of etiologic factors. Blood. 2003 Jan 15; 101(2):454-62.
Score: 0.031
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Leavey PJ, Gonzalez-Aller C, Thurman G, Kleinberg M, Rinckel L, Ambruso DW, Freeman S, Kuypers FA, Ambruso DR. A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity. J Biol Chem. 2002 Nov 22; 277(47):45181-7.
Score: 0.031
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Gardai S, Whitlock BB, Helgason C, Ambruso D, Fadok V, Bratton D, Henson PM. Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils. J Biol Chem. 2002 Feb 15; 277(7):5236-46.
Score: 0.030
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Ambruso DR, Johnston RB. Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system. J Clin Invest. 1981 Feb; 67(2):352-60.
Score: 0.028
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Ambruso DR, Altenburger KM, Johnston RB. Defective oxidative metabolism in newborn neutrophils: discrepancy between superoxide anion and hydroxyl radical generation. Pediatrics. 1979 Nov; 64(5 Pt 2 Suppl):722-5.
Score: 0.026
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Silliman CC, Voelkel NF, Allard JD, Elzi DJ, Tuder RM, Johnson JL, Ambruso DR. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. J Clin Invest. 1998 Apr 01; 101(7):1458-67.
Score: 0.023
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Silliman CC, Paterson AJ, Dickey WO, Stroneck DF, Popovsky MA, Caldwell SA, Ambruso DR. The association of biologically active lipids with the development of transfusion-related acute lung injury: a retrospective study. Transfusion. 1997 Jul; 37(7):719-26.
Score: 0.022
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Silliman CC, Johnson CA, Clay KL, Thurman GW, Ambruso DR. Compounds biologically similar to platelet activating factor are present in stored blood components. Lipids. 1993 May; 28(5):415-8.
Score: 0.016
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Ellison MA, Ambruso DR, Silliman CC. Therapeutic options for transfusion related acute lung injury; the potential of the G2A receptor. Curr Pharm Des. 2012; 18(22):3255-9.
Score: 0.015
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Sasada M, Kubo A, Nishimura T, Kakita T, Moriguchi T, Uchino H, Ambruso DR, Johnston RB. NADPH-dependent antibacterial activity in subcellular fractions of human neutrophils: interaction with granule constituents. Nihon Ketsueki Gakkai Zasshi. 1986 Sep; 49(6):1152-63.
Score: 0.010
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Williams DA, Tao W, Yang F, Kim C, Gu Y, Mansfield P, Levine JE, Petryniak B, Derrow CW, Harris C, Jia B, Zheng Y, Ambruso DR, Lowe JB, Atkinson SJ, Dinauer MC, Boxer L. Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. Blood. 2000 Sep 01; 96(5):1646-54.
Score: 0.007
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Hambidge KM, Norris DA, Githens JH, Ambruso D, Catalanotto FA. Hyperzincemia in a patient with pyoderma gangrenosum. J Pediatr. 1985 Mar; 106(3):450-1.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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