NikkiFarnsworth/uELZLTSvwvDNRkhdHnDilFGSoYfD0+wHFBWvvLDHw==Nikki Lynn Farnsworth39.74404140000000-104.838394500000006327Farnsworth, NikkiType 1 Diabetes MellitusBiomaterialsLynnAsst Professor Adjointprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:trainingAtOrganizationeducational organizationprns:trainingLocationtraining locationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:degreeEarneddegree earnedDepartmentDivisionvivo:educationalTrainingeducation and trainingEducational Trainingvivo:freetextKeywordkeywordsGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:middleNamemiddle name or initialvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 118709125128592Farnsworth NL, Mead BE, Antunez LR, Palmer AE, Bryant SJMatrix biology : journal of the International Society for Matrix BiologyFarnsworth NL, Mead BE, Antunez LR, Palmer AE, Bryant SJ. Ionic osmolytes and intracellular calcium regulate tissue production in chondrocytes cultured in a 3D charged hydrogel. Matrix Biol. 2014 Nov; 40:17-26.Matrix Biol2014-08-14T00:00:002014Ionic osmolytes and intracellular calcium regulate tissue production in chondrocytes cultured in a 3D charged hydrogel.LoriSusselLori Gail Sussel39.74404140000000-104.8383945000000011200Sussel, LoriProfessorAuthorship 139730126668311Farnsworth NL, Walter RL, Hemmati A, Westacott MJ, Benninger RKThe Journal of biological chemistryFarnsworth NL, Walter RL, Hemmati A, Westacott MJ, Benninger RK. Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cd. J Biol Chem. 2016 Feb 12; 291(7):3184-96.J Biol Chem2015-12-14T00:00:002015Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cd.1Professor3Asst Professor2Assoc Professor4Instructor2017-09-04NIHFARNSWORTH, NIKKI L.2014-09-05Regulation of islet gap junction coupling and function under inflammatory conditionsF32DK102276Principal InvestigatorAuthorship 164269228588099Westacott MJ, Farnsworth NL, St Clair JR, Poffenberger G, Heintz A, Ludin NW, Hart NJ, Powers AC, Benninger RKPDiabetesWestacott MJ, Farnsworth NL, St Clair JR, Poffenberger G, Heintz A, Ludin NW, Hart NJ, Powers AC, Benninger RKP. Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets. Diabetes. 2017 09; 66(9):2436-2445.Diabetes2017-06-06T00:00:002017Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets.Authorship 169366528895403Pe?a B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni LACS applied materials & interfacesPe?a B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni L. Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation. ACS Appl Mater Interfaces. 2017 Sep 20; 9(37):31645-31656.ACS Appl Mater Interfaces2017-09-12T00:00:002017Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation.22964019Farnsworth NL, Antunez LR, Bryant SJJournal of biomechanicsFarnsworth NL, Antunez LR, Bryant SJ. Influence of chondrocyte maturation on acute response to impact injury in PEG hydrogels. J Biomech. 2012 Oct 11; 45(15):2556-63.J Biomech2012-09-07T00:00:002012Influence of chondrocyte maturation on acute response to impact injury in PEG hydrogels.23404228Farnsworth NL, Antunez LR, Bryant SJBiotechnology and bioengineeringFarnsworth NL, Antunez LR, Bryant SJ. Dynamic compressive loading differentially regulates chondrocyte anabolic and catabolic activity with age. Biotechnol Bioeng. 2013 Jul; 110(7):2046-57.Biotechnol Bioeng2013-03-01T00:00:002013Dynamic compressive loading differentially regulates chondrocyte anabolic and catabolic activity with age.22796510Farnsworth N, Bensard C, Bryant SJOsteoarthritis and cartilageFarnsworth N, Bensard C, Bryant SJ. The role of the PCM in reducing oxidative stress induced by radical initiated photoencapsulation of chondrocytes in poly(ethylene glycol) hydrogels. Osteoarthritis Cartilage. 2012 Nov; 20(11):1326-35.Osteoarthritis Cartilage2012-07-10T00:00:002012The role of the PCM in reducing oxidative stress induced by radical initiated photoencapsulation of chondrocytes in poly(ethylene glycol) hydrogels.1775 Aurora Court2BDCBarbara Davis Center1775 Aurora CourtAurora80045-2536COD019902Anatomy502160.815878ChondrocytesAuthorship 190738130412665Farnsworth NL, Walter R, Piscopio RA, Schleicher WE, Benninger RKPThe Journal of physiologyFarnsworth NL, Walter R, Piscopio RA, Schleicher WE, Benninger RKP. Exendin-4 overcomes cytokine-induced decreases in gap junction coupling via protein kinase A and Epac2 in mouse and human islets. J Physiol. 2019 01; 597(2):431-447.J Physiol2018-11-29T00:00:002018Exendin-4 overcomes cytokine-induced decreases in gap junction coupling via protein kinase A and Epac2 in mouse and human islets.D017630Chemicals & Drugs20500.947678Connexins05/2007Rensselaer Polytechnic InstituteTroy, NYRensselaer Polytechnic Institute, Chemical EngineeringBSChemical Engineering08/2009University of Colorado BoulderBoulder, COUniversity of Colorado Boulder, Chemical and Biological EngineeringMSChemical and Biological Engineering05/2012University of Colorado BoulderBoulder, COUniversity of Colorado Boulder, Chemical and Biological EngineeringPhDChemical and Biological EngineeringXiaofanJiaXiaofan Jia39.74404140000000-104.8383945000000015278Jia, XiaofanAsst Professor-ResearchSOM-BDC Basic ResearchSOM-BDC Clinical Epi Research31021594Pe?a B, Maldonado M, Bonham AJ, Aguado BA, Dominguez-Alfaro A, Laughter M, Rowland TJ, Bardill J, Farnsworth NL, Alegret Ramon N, Taylor MRG, Anseth KS, Prato M, Shandas R, McKinsey TA, Park D, Mestroni LACS applied materials & interfacesPe?a B, Maldonado M, Bonham AJ, Aguado BA, Dominguez-Alfaro A, Laughter M, Rowland TJ, Bardill J, Farnsworth NL, Alegret Ramon N, Taylor MRG, Anseth KS, Prato M, Shandas R, McKinsey TA, Park D, Mestroni L. Gold Nanoparticle-Functionalized Reverse Thermal Gel for Tissue Engineering Applications. ACS Appl Mater Interfaces. 2019 May 22; 11(20):18671-18680.ACS Appl Mater Interfaces2019-05-07T00:00:002019Gold Nanoparticle-Functionalized Reverse Thermal Gel for Tissue Engineering Applications.D020662Chemicals & Drugs45610.949339Guanine Nucleotide Exchange FactorsAuthorship 2001669REN GENERAL OPERATIONSCEDC-BioengineeringD007515Anatomy1317490.621196Islets of LangerhansD017629Anatomy25590.932088Gap JunctionsChemical & Biological EnginSOM-MEDCardiologyUniversity of Colorado BoulderUniversity of Colorado Denver - Anschutz Medical CampusLuisaMestroniLuisa Mestroni39.74515960000000-104.840628000000001425Mestroni, Luisa0000-0003-1116-2286ProfessorLipingYuLiping Yu39.74404140000000-104.83839450000000178Yu, LipingAssoc Professor-ResearchHowardDavidsonHoward William Davidson39.74404140000000-104.838394500000001797Davidson, HowardAssociate ProfessorMakiNakayamaMaki Nakayama39.74404140000000-104.838394500000001946Nakayama, MakiAssociate ProfessorMarianRewersMarian J Rewers39.74404140000000-104.83839450000000299Rewers, MarianProfessorKristiAnsethKristi S Anseth40.00830860000000-105.24906720000000856Anseth, KristiDistinguished ProfessorStephanieBryantStephanie J Bryant40.00830860000000-105.24906720000000735Bryant, StephanieProfessorBrisaPena Castellanos8voJfLzSqQ/fOgk3aH/Sjl1EUYgCHE+tCEpf0//SHrN+OVxBBrisa Marisol Pena Castellanos39.74515960000000-104.840628000000006862Pena Castellanos, Brisa0000-0003-4224-6626Asst Professor-ResearchJoseMirandaJose G Miranda39.74773620000000-104.839213600000007116Miranda, Jose0000-0001-5366-3332Research InstructorRichardBenningerRichard K.P. Benninger39.74773620000000-104.839213600000004023Benninger, RichardProfessor2.28750.0076495785research areas3.742320.039717713coauthor of47.91882.8147760similar to1114selected publicationsAuthorship 226114432830549Corezola do Amaral ME, Kravets V, Dwulet JM, Farnsworth NL, Piscopio R, Schleicher WE, Miranda JG, Benninger RKPAmerican journal of physiology. Endocrinology and metabolismCorezola do Amaral ME, Kravets V, Dwulet JM, Farnsworth NL, Piscopio R, Schleicher WE, Miranda JG, Benninger RKP. Caloric restriction recovers impaired ?-cell-?-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice. Am J Physiol Endocrinol Metab. 2020 10 01; 319(4):E709-E720.Am J Physiol Endocrinol Metab2020-08-24T00:00:002020Caloric restriction recovers impaired ?-cell-?-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice.JasonBurdickJason A Burdick20550Burdick, JasonProfessorAuthorship 264703135837011Farnsworth NL, Piscopio RA, Schleicher WE, Ramirez DG, Miranda JG, Benninger RKPFrontiers in physiologyFarnsworth NL, Piscopio RA, Schleicher WE, Ramirez DG, Miranda JG, Benninger RKP. Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 Diabetes. Front Physiol. 2022; 13:913611.Front Physiol2022-06-28T00:00:002022Modulation of Gap Junction Coupling Within the Islet of Langerhans During the Development of Type 1 Diabetes.true1ProfessorProfessor37578890St Clair JR, Westacott MJ, Miranda J, Farnsworth NL, Kravets V, Schleicher WE, Dwulet JM, Levitt CH, Heintz A, Ludin NWF, Benninger RKPThe Journal of physiologySt Clair JR, Westacott MJ, Miranda J, Farnsworth NL, Kravets V, Schleicher WE, Dwulet JM, Levitt CH, Heintz A, Ludin NWF, Benninger RKP. Restoring connexin-36 function in diabetogenic environments precludes mouse and human islet dysfunction. J Physiol. 2023 09; 601(18):4053-4072.J Physiol2023-08-14T00:00:002023Restoring connexin-36 function in diabetogenic environments precludes mouse and human islet dysfunction.true1Research InstructorResearch InstructorAuthorship 2927544true1Assoc Professor-ResearchAssoc Professor-Researchtrue1Associate ProfessorAssociate Professortrue1Asst Professor-ResearchAsst Professor-Researchtrue1Asst Professor AdjointAsst Professor Adjointtrue1ProfessorProfessortrue1ProfessorProfessortrue1Asst Professor-ResearchAsst Professor-Researchtrue1Distinguished ProfessorDistinguished Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 463991Authorship 110836124583073Farnsworth NL, Benninger RKFEBS lettersFarnsworth NL, Benninger RK. New insights into the role of connexins in pancreatic islet function and diabetes. FEBS Lett. 2014 Apr 17; 588(8):1278-87.FEBS Lett2014-02-28T00:00:002014New insights into the role of connexins in pancreatic islet function and diabetes.Authorship 511371Authorship 667811Authorship 116848125172942Farnsworth NL, Hemmati A, Pozzoli M, Benninger RKThe Journal of physiologyFarnsworth NL, Hemmati A, Pozzoli M, Benninger RK. Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans. J Physiol. 2014 Oct 15; 592(20):4431-46.J Physiol2014-08-28T00:00:002014Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans.