 Connection
Leslie Leinwand to Rats
This is a "connection" page, showing publications Leslie Leinwand has written about Rats.
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Connection Strength |
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1.754 |
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Lee LA, Broadwell LJ, Buvoli M, Leinwand LA. Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart. J Am Heart Assoc. 2021 07 20; 10(14):e020965.
Score: 0.100
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Peter AK, Walker CJ, Ceccato T, Trexler CL, Ozeroff CD, Lugo KR, Perry AR, Anseth KS, Leinwand LA. Cardiac Fibroblasts Mediate a Sexually Dimorphic Fibrotic Response to ?-Adrenergic Stimulation. J Am Heart Assoc. 2021 06; 10(11):e018876.
Score: 0.099
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Ceccato TL, Starbuck RB, Hall JK, Walker CJ, Brown TE, Killgore JP, Anseth KS, Leinwand LA. Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment. J Am Heart Assoc. 2020 10 20; 9(19):e017025.
Score: 0.094
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Trexler CL, Odell AT, Jeong MY, Dowell RD, Leinwand LA. Transcriptome and Functional Profile of Cardiac Myocytes Is Influenced by Biological Sex. Circ Cardiovasc Genet. 2017 Oct; 10(5).
Score: 0.077
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Pugach EK, Blenck CL, Dragavon JM, Langer SJ, Leinwand LA. Estrogen receptor profiling and activity in cardiac myocytes. Mol Cell Endocrinol. 2016 08 15; 431:62-70.
Score: 0.070
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Blenck CL, Harvey PA, Reckelhoff JF, Leinwand LA. The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circ Res. 2016 Apr 15; 118(8):1294-312.
Score: 0.069
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Harvey PA, Leinwand LA. Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism. Cardiovasc Res. 2015 Jul 01; 107(1):66-77.
Score: 0.065
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Chung E, Yeung F, Leinwand LA. Calcineurin activity is required for cardiac remodelling in pregnancy. Cardiovasc Res. 2013 Dec 01; 100(3):402-10.
Score: 0.058
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Cosper PF, Harvey PA, Leinwand LA. Interferon-? causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis. Am J Pathol. 2012 Dec; 181(6):2038-46.
Score: 0.054
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Thompson RC, Buvoli M, Buvoli A, Leinwand LA. Myosin filament assembly requires a cluster of four positive residues located in the rod domain. FEBS Lett. 2012 Sep 21; 586(19):3008-12.
Score: 0.053
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Chung E, Yeung F, Leinwand LA. Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation. J Appl Physiol (1985). 2012 May; 112(9):1564-75.
Score: 0.052
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Buvoli M, Buvoli A, Leinwand LA. Effects of pathogenic proline mutations on myosin assembly. J Mol Biol. 2012 Feb 03; 415(5):807-18.
Score: 0.051
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Hughes TS, Langer SJ, Virtanen SI, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. J Gene Med. 2009 Sep; 11(9):782-90.
Score: 0.044
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Hughes TS, Langer SJ, Johnson KW, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Mol Ther. 2009 Jan; 17(1):88-94.
Score: 0.041
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Resnicow DI, Hooft AM, Harrison BC, Baker JE, Leinwand LA. GFP fails to inhibit actin-myosin interactions in vitro. Nat Methods. 2008 Mar; 5(3):212-3; author reply 213-4.
Score: 0.039
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Sucharov CC, Langer S, Bristow M, Leinwand L. Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C1029-37.
Score: 0.035
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Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA. Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy. Biochem Biophys Res Commun. 2005 Jan 07; 326(1):79-86.
Score: 0.032
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Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res. 2004 Aug 06; 95(3):253-60.
Score: 0.031
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Rice NA, Leinwand LA. Skeletal myosin heavy chain function in cultured lung myofibroblasts. J Cell Biol. 2003 Oct 13; 163(1):119-29.
Score: 0.029
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Maass A, Langer SJ, Oberdorf-Maass S, Bauer S, Neyses L, Leinwand LA. Rational promoter selection for gene transfer into cardiac cells. J Mol Cell Cardiol. 2003 Jul; 35(7):823-31.
Score: 0.029
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Sucharov CC, Mariner P, Long C, Bristow M, Leinwand L. Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter. J Biol Chem. 2003 Aug 15; 278(33):31233-9.
Score: 0.028
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Freeman K, Nakao K, Leinwand LA. Low sequence variation in the gene encoding the human beta-myosin heavy chain. Genomics. 2001 Aug; 76(1-3):73-80.
Score: 0.025
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Johnson CA, McGreig JE, Jeanfavre ST, Walklate J, Vera CD, Farr? M, Mulvihill DP, Baines AJ, Ridout M, Leinwand LA, Wass MN, Geeves MA. Identification of sequence changes in myosin II that adjust muscle contraction velocity. PLoS Biol. 2021 06; 19(6):e3001248.
Score: 0.025
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Maass A, Leinwand LA. Animal models of hypertrophic cardiomyopathy. Curr Opin Cardiol. 2000 May; 15(3):189-96.
Score: 0.023
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Tardiff JC, Hewett TE, Factor SM, Vikstrom KL, Robbins J, Leinwand LA. Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects. Am J Physiol Heart Circ Physiol. 2000 Feb; 278(2):H412-9.
Score: 0.023
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Roopnarine O, Leinwand LA. Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy. Biophys J. 1998 Dec; 75(6):3023-30.
Score: 0.021
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Li K, Welikson RE, Vikstrom KL, Leinwand LA. Direct gene transfer into the mouse heart. J Mol Cell Cardiol. 1997 May; 29(5):1499-504.
Score: 0.019
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Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 05; 351(6273):617-21.
Score: 0.017
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Kass-Eisler A, Li K, Leinwand LA. Prospects for gene therapy with direct injection of polynucleotides. Ann N Y Acad Sci. 1995 Nov 27; 772:232-40.
Score: 0.017
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Kass-Eisler A, Falck-Pedersen E, Elfenbein DH, Alvira M, Buttrick PM, Leinwand LA. The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Ther. 1994 Nov; 1(6):395-402.
Score: 0.016
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Sindhwani R, Ismail-Beigi F, Leinwand LA. Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression. J Biol Chem. 1994 Feb 04; 269(5):3272-6.
Score: 0.015
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Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA. Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):589-93.
Score: 0.015
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LeBlanc-Straceski JM, Fukui Y, Sohn RL, Spudich JA, Leinwand LA. Functional analysis of a cardiac myosin rod in Dictyostelium discoideum. Cell Motil Cytoskeleton. 1994; 27(4):313-26.
Score: 0.015
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Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11498-502.
Score: 0.015
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Buttrick PM, Kaplan ML, Kitsis RN, Leinwand LA. Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results. Circ Res. 1993 Jun; 72(6):1211-7.
Score: 0.014
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Vikstrom KL, Rovner AS, Saez CG, Bravo-Zehnder M, Straceski AJ, Leinwand LA. Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains. Cell Motil Cytoskeleton. 1993; 26(3):192-204.
Score: 0.014
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Buttrick PM, Kass A, Kitsis RN, Kaplan ML, Leinwand LA. Behavior of genes directly injected into the rat heart in vivo. Circ Res. 1992 Jan; 70(1):193-8.
Score: 0.013
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Kitsis RN, Buttrick PM, McNally EM, Kaplan ML, Leinwand LA. Hormonal modulation of a gene injected into rat heart in vivo. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4138-42.
Score: 0.012
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McNally EM, Bravo-Zehnder MM, Leinwand LA. Identification of sequences necessary for the association of cardiac myosin subunits. J Cell Biol. 1991 May; 113(3):585-90.
Score: 0.012
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Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol. 2011 Jul; 51(1):41-50.
Score: 0.012
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Fishman GI, Hertzberg EL, Spray DC, Leinwand LA. Expression of connexin43 in the developing rat heart. Circ Res. 1991 Mar; 68(3):782-7.
Score: 0.012
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McNally E, Sohn R, Frankel S, Leinwand L. Expression of myosin and actin in Escherichia coli. Methods Enzymol. 1991; 196:368-89.
Score: 0.012
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Fishman GI, Spray DC, Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol. 1990 Aug; 111(2):589-98.
Score: 0.012
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Rovner AS, McNally EM, Leinwand LA. Complete cDNA sequence of rat atrial myosin light chain 1: patterns of expression during development and with hypertension. Nucleic Acids Res. 1990 Mar 25; 18(6):1581-6.
Score: 0.011
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McNally EM, Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences. J Mol Biol. 1989 Dec 05; 210(3):665-71.
Score: 0.011
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McNally EM, Gianola KM, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat alpha cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7527-8.
Score: 0.011
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Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7529-30.
Score: 0.011
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Karsch-Mizrachi I, Travis M, Blau H, Leinwand LA. Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene. Nucleic Acids Res. 1989 Aug 11; 17(15):6167-79.
Score: 0.011
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Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, Falke JJ, Leinwand LA, Maier SF, Yin H, Rice KC, Watkins LR. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun. 2010 Jan; 24(1):83-95.
Score: 0.011
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Sloane E, Langer S, Jekich B, Mahoney J, Hughes T, Frank M, Seibert W, Huberty G, Coats B, Harrison J, Klinman D, Poole S, Maier S, Johnson K, Chavez R, Watkins LR, Leinwand L, Milligan E. Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Ther. 2009 Oct; 16(10):1210-22.
Score: 0.011
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Feghali R, Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J Cell Biol. 1989 May; 108(5):1791-7.
Score: 0.011
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McNally EM, Buttrick PM, Leinwand LA. Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension. Nucleic Acids Res. 1989 Apr 11; 17(7):2753-67.
Score: 0.011
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Sloane E, Ledeboer A, Seibert W, Coats B, van Strien M, Maier SF, Johnson KW, Chavez R, Watkins LR, Leinwand L, Milligan ED, Van Dam AM. Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy. Brain Behav Immun. 2009 Jan; 23(1):92-100.
Score: 0.010
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Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H246-59.
Score: 0.009
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Ledeboer A, Jekich BM, Sloane EM, Mahoney JH, Langer SJ, Milligan ED, Martin D, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR. Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun. 2007 Jul; 21(5):686-98.
Score: 0.009
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Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, Watkins LR. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 2006 Dec 15; 126(1-3):294-308.
Score: 0.009
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Saez L, Leinwand LA. Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle. Nucleic Acids Res. 1986 Apr 11; 14(7):2951-69.
Score: 0.009
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Sucharov CC, Mariner PD, Nunley KR, Long C, Leinwand L, Bristow MR. A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction. Am J Physiol Heart Circ Physiol. 2006 Sep; 291(3):H1299-308.
Score: 0.009
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Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci. 2005 Apr; 21(8):2136-48.
Score: 0.008
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Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain. 2005 Feb 25; 1:9.
Score: 0.008
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Johnston IN, Milligan ED, Wieseler-Frank J, Frank MG, Zapata V, Campisi J, Langer S, Martin D, Green P, Fleshner M, Leinwand L, Maier SF, Watkins LR. A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci. 2004 Aug 18; 24(33):7353-65.
Score: 0.008
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Leinwand LA, Saez L, McNally E, Nadal-Ginard B. Isolation and characterization of human myosin heavy chain genes. Proc Natl Acad Sci U S A. 1983 Jun; 80(12):3716-20.
Score: 0.007
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Weisbart RH, Yang F, Chan G, Wakelin R, Ferreri K, Zack DJ, Harrison B, Leinwand LA, Cole GM. Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb. Mol Immunol. 2003 Mar; 39(13):783-9.
Score: 0.007
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Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW. Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cell Motil Cytoskeleton. 2003 Feb; 54(2):105-21.
Score: 0.007
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Leinwand LA, Wydro RM, Nadal-Ginard B. Small RNA molecules related to the Alu family of repetitive DNA sequences. Mol Cell Biol. 1982 Nov; 2(11):1320-30.
Score: 0.007
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Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol. 1996 Apr; 70(4):2116-23.
Score: 0.004
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Kass-Eisler A, Leinwand L, Gall J, Bloom B, Falck-Pedersen E. Circumventing the immune response to adenovirus-mediated gene therapy. Gene Ther. 1996 Feb; 3(2):154-62.
Score: 0.004
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Smerdu V, Karsch-Mizrachi I, Campione M, Leinwand L, Schiaffino S. Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle. Am J Physiol. 1994 Dec; 267(6 Pt 1):C1723-8.
Score: 0.004
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Cho M, Hughes SM, Karsch-Mizrachi I, Travis M, Leinwand LA, Blau HM. Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception. J Cell Sci. 1994 Sep; 107 ( Pt 9):2361-71.
Score: 0.004
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Sweeney HL, Straceski AJ, Leinwand LA, Tikunov BA, Faust L. Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction. J Biol Chem. 1994 Jan 21; 269(3):1603-5.
Score: 0.004
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Buttrick PM, Kaplan M, Leinwand LA, Scheuer J. Alterations in gene expression in the rat heart after chronic pathological and physiological loads. J Mol Cell Cardiol. 1994 Jan; 26(1):61-7.
Score: 0.004
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Hughes SM, Cho M, Karsch-Mizrachi I, Travis M, Silberstein L, Leinwand LA, Blau HM. Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle. Dev Biol. 1993 Jul; 158(1):183-99.
Score: 0.004
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Ogata I, S?ez CG, Greenwel P, Ponce Mde L, Geerts A, Leinwand LA, Rojkind M. Rat liver fat-storing cell lines express sarcomeric myosin heavy chain mRNA and protein. Cell Motil Cytoskeleton. 1993; 26(2):125-32.
Score: 0.003
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Buttrick P, Malhotra A, Factor S, Greenen D, Leinwand L, Scheuer J. Effect of aging and hypertension on myosin biochemistry and gene expression in the rat heart. Circ Res. 1991 Mar; 68(3):645-52.
Score: 0.003
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Tsika RW, Bahl JJ, Leinwand LA, Morkin E. Thyroid hormone regulates expression of a transfected human alpha-myosin heavy-chain fusion gene in fetal rat heart cells. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):379-83.
Score: 0.003
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Eghbali M, Blumenfeld OO, Seifter S, Buttrick PM, Leinwand LA, Robinson TF, Zern MA, Giambrone MA. Localization of types I, III and IV collagen mRNAs in rat heart cells by in situ hybridization. J Mol Cell Cardiol. 1989 Jan; 21(1):103-13.
Score: 0.003
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Enat R, Jefferson DM, Ruiz-Opazo N, Gatmaitan Z, Leinwand LA, Reid LM. Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix. Proc Natl Acad Sci U S A. 1984 Mar; 81(5):1411-5.
Score: 0.002
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Gatmaitan Z, Jefferson DM, Ruiz-Opazo N, Biempica L, Arias IM, Dudas G, Leinwand LA, Reid LM. Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata. J Cell Biol. 1983 Oct; 97(4):1179-90.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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