 Connection
Leslie Leinwand to Animals
This is a "connection" page, showing publications Leslie Leinwand has written about Animals.
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3.040 |
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Lee LA, Barrick SK, Buvoli AE, Walklate J, Stump WT, Geeves M, Greenberg MJ, Leinwand LA. Distinct effects of two hearing loss-associated mutations in?the sarcomeric myosin MYH7b. J Biol Chem. 2023 05; 299(5):104631.
Score: 0.048
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Gotthardt M, Badillo-Lisakowski V, Parikh VN, Ashley E, Furtado M, Carmo-Fonseca M, Schudy S, Meder B, Grosch M, Steinmetz L, Crocini C, Leinwand L. Cardiac splicing as a diagnostic and therapeutic target. Nat Rev Cardiol. 2023 08; 20(8):517-530.
Score: 0.048
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Martin TG, Juarros MA, Leinwand LA. Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential. Nat Rev Cardiol. 2023 05; 20(5):347-363.
Score: 0.048
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Lee LA, Barrick SK, Meller A, Walklate J, Lotthammer JM, Tay JW, Stump WT, Bowman G, Geeves MA, Greenberg MJ, Leinwand LA. Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles. J Biol Chem. 2023 01; 299(1):102657.
Score: 0.047
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Tan Y, Martin TG, Harrison BC, Leinwand LA. Utility of the burmese Python as a model for studying plasticity of extreme physiological systems. J Muscle Res Cell Motil. 2023 Jun; 44(2):95-106.
Score: 0.047
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Magida JA, Tan Y, Wall CE, Harrison BC, Marr TG, Peter AK, Riquelme CA, Leinwand LA. Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage. J Gen Physiol. 2022 04 04; 154(4).
Score: 0.045
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Muehleman DL, Crocini C, Swearingen AR, Ozeroff CD, Leinwand LA. Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus specific. Am J Physiol Heart Circ Physiol. 2022 05 01; 322(5):H785-H797.
Score: 0.045
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Lee LA, Broadwell LJ, Buvoli M, Leinwand LA. Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart. J Am Heart Assoc. 2021 07 20; 10(14):e020965.
Score: 0.043
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Walker CJ, Schroeder ME, Aguado BA, Anseth KS, Leinwand LA. Matters of the heart: Cellular sex differences. J Mol Cell Cardiol. 2021 11; 160:42-55.
Score: 0.043
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Peter AK, Walker CJ, Ceccato T, Trexler CL, Ozeroff CD, Lugo KR, Perry AR, Anseth KS, Leinwand LA. Cardiac Fibroblasts Mediate a Sexually Dimorphic Fibrotic Response to ?-Adrenergic Stimulation. J Am Heart Assoc. 2021 06; 10(11):e018876.
Score: 0.043
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Ceccato TL, Starbuck RB, Hall JK, Walker CJ, Brown TE, Killgore JP, Anseth KS, Leinwand LA. Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment. J Am Heart Assoc. 2020 10 20; 9(19):e017025.
Score: 0.041
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Bjorkman KK, Guess MG, Harrison BC, Polmear MM, Peter AK, Leinwand LA. miR-206 enforces a slow muscle phenotype. J Cell Sci. 2020 08 11; 133(15).
Score: 0.040
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Bjorkman KK, Buvoli M, Pugach EK, Polmear MM, Leinwand LA. miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation. Skelet Muscle. 2019 12 02; 9(1):31.
Score: 0.039
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Peter AK, Rossi AC, Buvoli M, Ozeroff CD, Crocini C, Perry AR, Buvoli AE, Lee LA, Leinwand LA. Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy. J Am Heart Assoc. 2019 08 06; 8(15):e013318.
Score: 0.038
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Crocini C, Walker CJ, Anseth KS, Leinwand LA. Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness. Prog Biophys Mol Biol. 2020 08; 154:71-79.
Score: 0.037
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Lee LA, Karabina A, Broadwell LJ, Leinwand LA. The ancient sarcomeric myosins found in specialized muscles. Skelet Muscle. 2019 03 05; 9(1):7.
Score: 0.037
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Chung E, Haizlip KM, Leinwand LA. Pregnancy late in rodent life has detrimental effects on the heart. Am J Physiol Heart Circ Physiol. 2018 09 01; 315(3):H482-H491.
Score: 0.035
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Ujfalusi Z, Vera CD, Mijailovich SM, Svicevic M, Yu EC, Kawana M, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. J Biol Chem. 2018 06 08; 293(23):9017-9029.
Score: 0.034
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Trexler CL, Odell AT, Jeong MY, Dowell RD, Leinwand LA. Transcriptome and Functional Profile of Cardiac Myocytes Is Influenced by Biological Sex. Circ Cardiovasc Genet. 2017 Oct; 10(5).
Score: 0.033
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Luckey SW, Haines CD, Konhilas JP, Luczak ED, Messmer-Kratzsch A, Leinwand LA. Cyclin D2 is a critical mediator of exercise-induced cardiac hypertrophy. Exp Biol Med (Maywood). 2017 Dec; 242(18):1820-1830.
Score: 0.033
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Peter AK, Crocini C, Leinwand LA. Expanding our scientific horizons: utilization of unique model organisms in biological research. EMBO J. 2017 08 15; 36(16):2311-2314.
Score: 0.033
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Vega RB, Konhilas JP, Kelly DP, Leinwand LA. Molecular Mechanisms Underlying Cardiac Adaptation to Exercise. Cell Metab. 2017 May 02; 25(5):1012-1026.
Score: 0.032
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Wan W, Leinwand L. Computational Approach to Measuring Myocyte Disarray in Animal Models of Heart Disease. Curr Protoc Hum Genet. 2017 04 06; 93:15.11.1-15.11.9.
Score: 0.032
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Peter AK, Bjerke MA, Leinwand LA. Biology of the cardiac myocyte in heart disease. Mol Biol Cell. 2016 07 15; 27(14):2149-60.
Score: 0.031
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Pugach EK, Blenck CL, Dragavon JM, Langer SJ, Leinwand LA. Estrogen receptor profiling and activity in cardiac myocytes. Mol Cell Endocrinol. 2016 08 15; 431:62-70.
Score: 0.030
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Blenck CL, Harvey PA, Reckelhoff JF, Leinwand LA. The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circ Res. 2016 Apr 15; 118(8):1294-312.
Score: 0.030
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Pugach EK, Richmond PA, Azofeifa JG, Dowell RD, Leinwand LA. Prolonged Cre expression driven by the a-myosin heavy chain promoter can be cardiotoxic. J Mol Cell Cardiol. 2015 Sep; 86:54-61.
Score: 0.028
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Harvey PA, Leinwand LA. Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism. Cardiovasc Res. 2015 Jul 01; 107(1):66-77.
Score: 0.028
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Guess MG, Barthel KK, Harrison BC, Leinwand LA. miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One. 2015; 10(2):e0118229.
Score: 0.028
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Haizlip KM, Harrison BC, Leinwand LA. Sex-based differences in skeletal muscle kinetics and fiber-type composition. Physiology (Bethesda). 2015 Jan; 30(1):30-9.
Score: 0.027
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Konhilas JP, Chen H, Luczak E, McKee LA, Regan J, Watson PA, Stauffer BL, Khalpey ZI, Mckinsey TA, Horn T, LaFleur B, Leinwand LA. Diet and sex modify exercise and cardiac adaptation in the mouse. Am J Physiol Heart Circ Physiol. 2015 Jan 15; 308(2):H135-45.
Score: 0.027
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Harvey PA, Leinwand LA. Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor. Mol Cell Endocrinol. 2015 Jan 05; 399:330-5.
Score: 0.027
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Magida JA, Leinwand LA. Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy. EMBO Mol Med. 2014 04; 6(4):482-95.
Score: 0.026
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Chung E, Leinwand LA. Pregnancy as a cardiac stress model. Cardiovasc Res. 2014 Mar 15; 101(4):561-70.
Score: 0.026
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Harvey PA, Wall C, Luckey SW, Langer S, Leinwand LA. The python project: a unique model for extending research opportunities to undergraduate students. CBE Life Sci Educ. 2014; 13(4):698-710.
Score: 0.026
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Chung E, Yeung F, Leinwand LA. Calcineurin activity is required for cardiac remodelling in pregnancy. Cardiovasc Res. 2013 Dec 01; 100(3):402-10.
Score: 0.025
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Cosper PF, Harvey PA, Leinwand LA. Interferon-? causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis. Am J Pathol. 2012 Dec; 181(6):2038-46.
Score: 0.023
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Chung E, Heimiller J, Leinwand LA. Distinct cardiac transcriptional profiles defining pregnancy and exercise. PLoS One. 2012; 7(7):e42297.
Score: 0.023
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Haines CD, Harvey PA, Luczak ED, Barthel KK, Konhilas JP, Watson PA, Stauffer BL, Leinwand LA. Estrogenic compounds are not always cardioprotective and can be lethal in males with genetic heart disease. Endocrinology. 2012 Sep; 153(9):4470-9.
Score: 0.023
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Haines CD, Harvey PA, Leinwand LA. Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner. Endocrinology. 2012 Sep; 153(9):4480-90.
Score: 0.023
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Thompson RC, Buvoli M, Buvoli A, Leinwand LA. Myosin filament assembly requires a cluster of four positive residues located in the rod domain. FEBS Lett. 2012 Sep 21; 586(19):3008-12.
Score: 0.023
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Yeung F, Chung E, Guess MG, Bell ML, Leinwand LA. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 2012 Aug; 40(15):7303-18.
Score: 0.023
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Chung E, Yeung F, Leinwand LA. Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation. J Appl Physiol (1985). 2012 May; 112(9):1564-75.
Score: 0.022
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Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Identification of functional differences between recombinant human a and ? cardiac myosin motors. Cell Mol Life Sci. 2012 07; 69(13):2261-77.
Score: 0.022
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Buvoli M, Buvoli A, Leinwand LA. Effects of pathogenic proline mutations on myosin assembly. J Mol Biol. 2012 Feb 03; 415(5):807-18.
Score: 0.022
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Riquelme CA, Magida JA, Harrison BC, Wall CE, Marr TG, Secor SM, Leinwand LA. Fatty acids identified in the Burmese python promote beneficial cardiac growth. Science. 2011 Oct 28; 334(6055):528-31.
Score: 0.022
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Cosper PF, Leinwand LA. Myosin heavy chain is not selectively decreased in murine cancer cachexia. Int J Cancer. 2012 Jun 01; 130(11):2722-7.
Score: 0.022
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Luczak ED, Barthel KK, Stauffer BL, Konhilas JP, Cheung TH, Leinwand LA. Remodeling the cardiac transcriptional landscape with diet. Physiol Genomics. 2011 Jun 28; 43(12):772-80.
Score: 0.021
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Leinwand LA, Moss RL. Medicine. Chemically tuned myosin motors. Science. 2011 Mar 18; 331(6023):1392-3.
Score: 0.021
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Cosper PF, Leinwand LA. Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner. Cancer Res. 2011 Mar 01; 71(5):1710-20.
Score: 0.021
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Wall CE, Cozza S, Riquelme CA, McCombie WR, Heimiller JK, Marr TG, Leinwand LA. Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation. Physiol Genomics. 2011 Jan 01; 43(2):69-76.
Score: 0.021
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Konhilas JP, Boucek DM, Horn TR, Johnson GL, Leinwand LA. The role of MEKK1 in hypertrophic cardiomyopathy. Int Heart J. 2010 Jul; 51(4):277-84.
Score: 0.020
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Bell ML, Buvoli M, Leinwand LA. Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Mol Cell Biol. 2010 Apr; 30(8):1937-45.
Score: 0.020
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Bhupathy P, Haines CD, Leinwand LA. Influence of sex hormones and phytoestrogens on heart disease in men and women. Womens Health (Lond). 2010 Jan; 6(1):77-95.
Score: 0.019
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Hughes TS, Langer SJ, Virtanen SI, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. J Gene Med. 2009 Sep; 11(9):782-90.
Score: 0.019
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Luckey SW, Walker LA, Smyth T, Mansoori J, Messmer-Kratzsch A, Rosenzweig A, Olson EN, Leinwand LA. The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2009 May; 46(5):739-47.
Score: 0.018
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Luczak ED, Leinwand LA. Sex-based cardiac physiology. Annu Rev Physiol. 2009; 71:1-18.
Score: 0.018
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Chung E, Leinwand LA. Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins. Circ Res. 2008 Dec 05; 103(12):1351-3.
Score: 0.018
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Hughes TS, Langer SJ, Johnson KW, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Mol Ther. 2009 Jan; 17(1):88-94.
Score: 0.018
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Resnicow DI, Hooft AM, Harrison BC, Baker JE, Leinwand LA. GFP fails to inhibit actin-myosin interactions in vitro. Nat Methods. 2008 Mar; 5(3):212-3; author reply 213-4.
Score: 0.017
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Harrison BC, Leinwand LA. Fighting fat with muscle: bulking up to slim down. Cell Metab. 2008 Feb; 7(2):97-8.
Score: 0.017
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Konhilas JP, Leinwand LA. The effects of biological sex and diet on the development of heart failure. Circulation. 2007 Dec 04; 116(23):2747-59.
Score: 0.017
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Buvoli M, Buvoli A, Leinwand LA. Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse. PLoS One. 2007 May 09; 2(5):e427.
Score: 0.016
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Leinwand LA. Molecular events underlying pregnancy-induced cardiomyopathy. Cell. 2007 Feb 09; 128(3):437-8.
Score: 0.016
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Luckey SW, Mansoori J, Fair K, Antos CL, Olson EN, Leinwand LA. Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males. Am J Physiol Heart Circ Physiol. 2007 Feb; 292(2):H838-45.
Score: 0.015
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Sucharov CC, Langer S, Bristow M, Leinwand L. Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C1029-37.
Score: 0.015
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Konhilas JP, Leinwand LA. Partnering up for cardiac hypertrophy. Circ Res. 2006 Apr 28; 98(8):985-7.
Score: 0.015
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Beylkin DH, Allen DL, Leinwand LA. MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes. Dev Biol. 2006 Jun 15; 294(2):541-53.
Score: 0.015
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Konhilas JP, Watson PA, Maass A, Boucek DM, Horn T, Stauffer BL, Luckey SW, Rosenberg P, Leinwand LA. Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res. 2006 Mar 03; 98(4):540-8.
Score: 0.015
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Stauffer BL, Konhilas JP, Luczak ED, Leinwand LA. Soy diet worsens heart disease in mice. J Clin Invest. 2006 Jan; 116(1):209-16.
Score: 0.015
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Konhilas JP, Widegren U, Allen DL, Paul AC, Cleary A, Leinwand LA. Loaded wheel running and muscle adaptation in the mouse. Am J Physiol Heart Circ Physiol. 2005 Jul; 289(1):H455-65.
Score: 0.014
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Allen DL, Weber JN, Sycuro LK, Leinwand LA. Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo. J Biol Chem. 2005 Apr 29; 280(17):17126-34.
Score: 0.014
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Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA. Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy. Biochem Biophys Res Commun. 2005 Jan 07; 326(1):79-86.
Score: 0.014
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Maass AH, Ikeda K, Oberdorf-Maass S, Maier SK, Leinwand LA. Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. Circulation. 2004 Oct 12; 110(15):2102-9.
Score: 0.013
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Konhilas JP, Maass AH, Luckey SW, Stauffer BL, Olson EN, Leinwand LA. Sex modifies exercise and cardiac adaptation in mice. Am J Physiol Heart Circ Physiol. 2004 Dec; 287(6):H2768-76.
Score: 0.013
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Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res. 2004 Aug 06; 95(3):253-60.
Score: 0.013
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Rice NA, Leinwand LA. Skeletal myosin heavy chain function in cultured lung myofibroblasts. J Cell Biol. 2003 Oct 13; 163(1):119-29.
Score: 0.013
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Leinwand LA. Hope for a broken heart? Cell. 2003 Sep 19; 114(6):658-9.
Score: 0.013
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Leinwand LA. Sex is a potent modifier of the cardiovascular system. J Clin Invest. 2003 Aug; 112(3):302-7.
Score: 0.012
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Maass AH, Leinwand LA. Mechanisms of the pathogenesis of troponin T-based familial hypertrophic cardiomyopathy. Trends Cardiovasc Med. 2003 Aug; 13(6):232-7.
Score: 0.012
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Harrison BC, Allen DL, Girten B, Stodieck LS, Kostenuik PJ, Bateman TA, Morony S, Lacey D, Leinwand LA. Skeletal muscle adaptations to microgravity exposure in the mouse. J Appl Physiol (1985). 2003 Dec; 95(6):2462-70.
Score: 0.012
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Haubold KW, Allen DL, Capetanaki Y, Leinwand LA. Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance. J Appl Physiol (1985). 2003 Oct; 95(4):1617-22.
Score: 0.012
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Maass A, Langer SJ, Oberdorf-Maass S, Bauer S, Neyses L, Leinwand LA. Rational promoter selection for gene transfer into cardiac cells. J Mol Cell Cardiol. 2003 Jul; 35(7):823-31.
Score: 0.012
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Sucharov CC, Mariner P, Long C, Bristow M, Leinwand L. Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter. J Biol Chem. 2003 Aug 15; 278(33):31233-9.
Score: 0.012
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Russell AJ, DuVall M, Barthel B, Qian Y, Peter AK, Newell-Stamper BL, Hunt K, Lehman S, Madden M, Schlachter S, Robertson B, Van Deusen A, Rodriguez HM, Vera C, Su Y, Claflin DR, Brooks SV, Nghiem P, Rutledge A, Juehne TI, Yu J, Barton ER, Luo YE, Patsalos A, Nagy L, Sweeney HL, Leinwand LA, Koch K. Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy. J Clin Invest. 2023 05 15; 133(10).
Score: 0.012
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Buvoli M, Buvoli A, Leinwand LA. Suppressor tRNAs: protocols and applications for cardiac gene transfer. Methods Mol Biol. 2003; 219:115-27.
Score: 0.012
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Allen DL, Leinwand LA. Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter. J Biol Chem. 2002 Nov 22; 277(47):45323-30.
Score: 0.012
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Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Circulation. 2022 08 30; 146(9):699-714.
Score: 0.012
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Axelsson Raja A, Wakimoto H, DeLaughter DM, Reichart D, Gorham J, Conner DA, Lun M, Probst CK, Sakai N, Knipe RS, Montesi SB, Shea B, Adam LP, Leinwand LA, Wan W, Choi ES, Lindberg EL, Patone G, Noseda M, H?bner N, Seidman CE, Tager AM, Seidman JG, Ho CY. Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model. Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2204174119.
Score: 0.012
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Allen DL, Harrison BC, Leinwand LA. Molecular and genetic approaches to studying exercise performance and adaptation. Exerc Sport Sci Rev. 2002 Jul; 30(3):99-105.
Score: 0.012
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Lerman I, Harrison BC, Freeman K, Hewett TE, Allen DL, Robbins J, Leinwand LA. Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. J Appl Physiol (1985). 2002 Jun; 92(6):2245-55.
Score: 0.011
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Buvoli M, Langer SJ, Bialik S, Leinwand LA. Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors. Gene Ther. 2002 Feb; 9(3):227-31.
Score: 0.011
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Aguado BA, Walker CJ, Grim JC, Schroeder ME, Batan D, Vogt BJ, Rodriguez AG, Schwisow JA, Moulton KS, Weiss RM, Heistad DD, Leinwand LA, Anseth KS. Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Circulation. 2022 02 15; 145(7):513-530.
Score: 0.011
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Harrison BC, Bell ML, Allen DL, Byrnes WC, Leinwand LA. Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice. J Appl Physiol (1985). 2002 Jan; 92(1):313-22.
Score: 0.011
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Buvoli M, Leinwand LA. Direct gene transfer into mouse heart. Methods Enzymol. 2002; 346:134-42.
Score: 0.011
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Maass A, Konhilas JP, Stauffer BL, Leinwand LA. From sarcomeric mutations to heart disease: understanding familial hypertrophic cardiomyopathy. Cold Spring Harb Symp Quant Biol. 2002; 67:409-15.
Score: 0.011
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Allen DL, Sartorius CA, Sycuro LK, Leinwand LA. Different pathways regulate expression of the skeletal myosin heavy chain genes. J Biol Chem. 2001 Nov 23; 276(47):43524-33.
Score: 0.011
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Freeman K, Nakao K, Leinwand LA. Low sequence variation in the gene encoding the human beta-myosin heavy chain. Genomics. 2001 Aug; 76(1-3):73-80.
Score: 0.011
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Johnson CA, McGreig JE, Jeanfavre ST, Walklate J, Vera CD, Farr? M, Mulvihill DP, Baines AJ, Ridout M, Leinwand LA, Wass MN, Geeves MA. Identification of sequence changes in myosin II that adjust muscle contraction velocity. PLoS Biol. 2021 06; 19(6):e3001248.
Score: 0.011
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Allen DL, Harrison BC, Maass A, Bell ML, Byrnes WC, Leinwand LA. Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse. J Appl Physiol (1985). 2001 May; 90(5):1900-8.
Score: 0.011
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Maass A, Leinwand LA. A role for calreticulin in the adult heart? J Clin Invest. 2001 May; 107(10):1223-5.
Score: 0.011
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Walker CJ, Crocini C, Ramirez D, Killaars AR, Grim JC, Aguado BA, Clark K, Allen MA, Dowell RD, Leinwand LA, Anseth KS. Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts. Nat Biomed Eng. 2021 12; 5(12):1485-1499.
Score: 0.011
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Freeman K, Lerman I, Kranias EG, Bohlmeyer T, Bristow MR, Lefkowitz RJ, Iaccarino G, Koch WJ, Leinwand LA. Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy. J Clin Invest. 2001 Apr; 107(8):967-74.
Score: 0.011
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Leinwand LA. Calcineurin inhibition and cardiac hypertrophy: a matter of balance. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):2947-9.
Score: 0.011
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Allen DL, Harrison BC, Sartorius C, Byrnes WC, Leinwand LA. Mutation of the IIB myosin heavy chain gene results in muscle fiber loss and compensatory hypertrophy. Am J Physiol Cell Physiol. 2001 Mar; 280(3):C637-45.
Score: 0.011
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Allen DL, Leinwand LA. Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains. Dev Biol. 2001 Jan 15; 229(2):383-95.
Score: 0.010
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Freeman K, Colon-Rivera C, Olsson MC, Moore RL, Weinberger HD, Grupp IL, Vikstrom KL, Iaccarino G, Koch WJ, Leinwand LA. Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene. Am J Physiol Heart Circ Physiol. 2001 Jan; 280(1):H151-9.
Score: 0.010
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Walker GA, Guerrero IA, Leinwand LA. Myofibroblasts: molecular crossdressers. Curr Top Dev Biol. 2001; 51:91-107.
Score: 0.010
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Allen DL, Harrison BC, Leinwand LA. Inactivation of myosin heavy chain genes in the mouse: diverse and unexpected phenotypes. Microsc Res Tech. 2000 Sep 15; 50(6):492-9.
Score: 0.010
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Buvoli M, Buvoli A, Leinwand LA. Suppression of nonsense mutations in cell culture and mice by multimerized suppressor tRNA genes. Mol Cell Biol. 2000 May; 20(9):3116-24.
Score: 0.010
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Maass A, Leinwand LA. Animal models of hypertrophic cardiomyopathy. Curr Opin Cardiol. 2000 May; 15(3):189-96.
Score: 0.010
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Tardiff JC, Hewett TE, Factor SM, Vikstrom KL, Robbins J, Leinwand LA. Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects. Am J Physiol Heart Circ Physiol. 2000 Feb; 278(2):H412-9.
Score: 0.010
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I?igo MR, Amorese AJ, Tarpey MD, Balestrieri NP, Jones KG, Patteson DJ, Jackson KC, Torres MJ, Lin CT, Smith CD, Heden TD, McMillin SL, Weyrauch LA, Stanley EC, Schmidt CA, Kilburg-Basnyat BB, Reece SW, Psaltis CE, Leinwand LA, Funai K, McClung JM, Gowdy KM, Witczak CA, Lowe DA, Neufer PD, Spangenburg EE. Estrogen receptor-a in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation. Mol Metab. 2020 04; 34:1-15.
Score: 0.010
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Johnson CA, Walklate J, Svicevic M, Mijailovich SM, Vera C, Karabina A, Leinwand LA, Geeves MA. The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles. J Biol Chem. 2019 09 27; 294(39):14267-14278.
Score: 0.009
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Tardiff JC, Hewett TE, Palmer BM, Olsson C, Factor SM, Moore RL, Robbins J, Leinwand LA. Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. J Clin Invest. 1999 Aug; 104(4):469-81.
Score: 0.009
-
Weiss A, Schiaffino S, Leinwand LA. Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity. J Mol Biol. 1999 Jul 02; 290(1):61-75.
Score: 0.009
-
Welikson RE, Buck SH, Patel JR, Moss RL, Vikstrom KL, Factor SM, Miyata S, Weinberger HD, Leinwand LA. Cardiac myosin heavy chains lacking the light chain binding domain cause hypertrophic cardiomyopathy in mice. Am J Physiol. 1999 06; 276(6):H2148-58.
Score: 0.009
-
Roopnarine O, Leinwand LA. Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy. Biophys J. 1998 Dec; 75(6):3023-30.
Score: 0.009
-
Tardiff JC, Factor SM, Tompkins BD, Hewett TE, Palmer BM, Moore RL, Schwartz S, Robbins J, Leinwand LA. A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J Clin Invest. 1998 Jun 15; 101(12):2800-11.
Score: 0.009
-
Sartorius CA, Lu BD, Acakpo-Satchivi L, Jacobsen RP, Byrnes WC, Leinwand LA. Myosin heavy chains IIa and IId are functionally distinct in the mouse. J Cell Biol. 1998 May 18; 141(4):943-53.
Score: 0.009
-
Vikstrom KL, Bohlmeyer T, Factor SM, Leinwand LA. Hypertrophy, pathology, and molecular markers of cardiac pathogenesis. Circ Res. 1998 Apr 20; 82(7):773-8.
Score: 0.009
-
Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O'Rourke B, Aon MA, Abraham MR. Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models. JCI Insight. 2018 03 22; 3(6).
Score: 0.009
-
Mayer DC, Leinwand LA. Sarcomeric gene expression and contractility in myofibroblasts. J Cell Biol. 1997 Dec 15; 139(6):1477-84.
Score: 0.008
-
Li K, Welikson RE, Vikstrom KL, Leinwand LA. Direct gene transfer into the mouse heart. J Mol Cell Cardiol. 1997 May; 29(5):1499-504.
Score: 0.008
-
Sohn RL, Vikstrom KL, Strauss M, Cohen C, Szent-Gyorgyi AG, Leinwand LA. A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. J Mol Biol. 1997 Feb 21; 266(2):317-30.
Score: 0.008
-
Vikstrom KL, Seiler SH, Sohn RL, Strauss M, Weiss A, Welikson RE, Leinwand LA. The vertebrate myosin heavy chain: genetics and assembly properties. Cell Struct Funct. 1997 Feb; 22(1):123-9.
Score: 0.008
-
Soto SM, Blake AC, Wesolowski SR, Rozance PJ, Barthel KB, Gao B, Hetrick B, McCurdy CE, Garza NG, Hay WW, Leinwand LA, Friedman JE, Brown LD. Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro. J Endocrinol. 2017 03; 232(3):475-491.
Score: 0.008
-
Li K, Buvoli M, Welikson RE, Vikstrom KL, Leinwand LA. Advances in cardiovascular gene transfer. Cardiologia. 1997 Jan; 42(1):39-46.
Score: 0.008
-
Kass-Eisler A, Leinwand LA. DNA- and adenovirus-mediated gene transfer into cardiac muscle. Methods Cell Biol. 1997; 52:423-37.
Score: 0.008
-
Vikstrom KL, Factor SM, Leinwand LA. Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy. Mol Med. 1996 Sep; 2(5):556-67.
Score: 0.008
-
Feinstein-Linial M, Buvoli M, Buvoli A, Sadeh M, Dabby R, Straussberg R, Shelef I, Dayan D, Leinwand LA, Birk OS. Two novel MYH7 proline substitutions cause Laing Distal Myopathy-like phenotypes with variable expressivity and neck extensor contracture. BMC Med Genet. 2016 08 12; 17(1):57.
Score: 0.008
-
Edwards JG, Lyons GE, Micales BK, Malhotra A, Factor S, Leinwand LA. Cardiomyopathy in transgenic myf5 mice. Circ Res. 1996 Mar; 78(3):379-87.
Score: 0.007
-
Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 05; 351(6273):617-21.
Score: 0.007
-
Weiss A, Leinwand LA. The mammalian myosin heavy chain gene family. Annu Rev Cell Dev Biol. 1996; 12:417-39.
Score: 0.007
-
Kass-Eisler A, Li K, Leinwand LA. Prospects for gene therapy with direct injection of polynucleotides. Ann N Y Acad Sci. 1995 Nov 27; 772:232-40.
Score: 0.007
-
Hajj GP, Chu Y, Lund DD, Magida JA, Funk ND, Brooks RM, Baumbach GL, Zimmerman KA, Davis MK, El Accaoui RN, Hameed T, Doshi H, Chen B, Leinwand LA, Song LS, Heistad DD, Weiss RM. Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice. Arterioscler Thromb Vasc Biol. 2015 Jul; 35(7):1653-62.
Score: 0.007
-
Gardin JM, Siri FM, Kitsis RN, Edwards JG, Leinwand LA. Echocardiographic assessment of left ventricular mass and systolic function in mice. Circ Res. 1995 May; 76(5):907-14.
Score: 0.007
-
Vikstrom KL, Factor SM, Leinwand LA. A murine model for hypertrophic cardiomyopathy. Z Kardiol. 1995; 84 Suppl 4:49-54.
Score: 0.007
-
Kass-Eisler A, Falck-Pedersen E, Elfenbein DH, Alvira M, Buttrick PM, Leinwand LA. The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Ther. 1994 Nov; 1(6):395-402.
Score: 0.007
-
Wang H, Leinwand LA, Anseth KS. Roles of transforming growth factor-?1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. FASEB J. 2014 Oct; 28(10):4551-62.
Score: 0.007
-
Sindhwani R, Ismail-Beigi F, Leinwand LA. Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression. J Biol Chem. 1994 Feb 04; 269(5):3272-6.
Score: 0.006
-
Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA. Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):589-93.
Score: 0.006
-
Weiss A, Mayer DC, Leinwand LA. Diversity of myosin-based motility: multiple genes and functions. Soc Gen Physiol Ser. 1994; 49:159-71.
Score: 0.006
-
LeBlanc-Straceski JM, Fukui Y, Sohn RL, Spudich JA, Leinwand LA. Functional analysis of a cardiac myosin rod in Dictyostelium discoideum. Cell Motil Cytoskeleton. 1994; 27(4):313-26.
Score: 0.006
-
Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11498-502.
Score: 0.006
-
Wang H, Tibbitt MW, Langer SJ, Leinwand LA, Anseth KS. Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19336-41.
Score: 0.006
-
Bloemink MJ, Deacon JC, Resnicow DI, Leinwand LA, Geeves MA. The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. J Biol Chem. 2013 Sep 20; 288(38):27469-27479.
Score: 0.006
-
Wang H, Sridhar B, Leinwand LA, Anseth KS. Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves. PLoS One. 2013; 8(7):e69667.
Score: 0.006
-
Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human ?-cardiac myosin motor function. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12607-12.
Score: 0.006
-
Buttrick PM, Kaplan ML, Kitsis RN, Leinwand LA. Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results. Circ Res. 1993 Jun; 72(6):1211-7.
Score: 0.006
-
Xu R, Andres-Mateos E, Mejias R, MacDonald EM, Leinwand LA, Merriman DK, Fink RH, Cohn RD. Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. Exp Neurol. 2013 Sep; 247:392-401.
Score: 0.006
-
Vikstrom KL, Rovner AS, Saez CG, Bravo-Zehnder M, Straceski AJ, Leinwand LA. Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains. Cell Motil Cytoskeleton. 1993; 26(3):192-204.
Score: 0.006
-
Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM. A PGC-1a isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012 Dec 07; 151(6):1319-31.
Score: 0.006
-
Andres-Mateos E, Brinkmeier H, Burks TN, Mejias R, Files DC, Steinberger M, Soleimani A, Marx R, Simmers JL, Lin B, Finanger Hedderick E, Marr TG, Lin BM, Hourd? C, Leinwand LA, Kuhl D, F?ller M, Vogelsang S, Hernandez-Diaz I, Vaughan DK, Alvarez de la Rosa D, Lang F, Cohn RD. Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. EMBO Mol Med. 2013 01; 5(1):80-91.
Score: 0.006
-
Andres-Mateos E, Mejias R, Soleimani A, Lin BM, Burks TN, Marx R, Lin B, Zellars RC, Zhang Y, Huso DL, Marr TG, Leinwand LA, Merriman DK, Cohn RD. Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. PLoS One. 2012; 7(11):e48884.
Score: 0.006
-
Moore JR, Leinwand L, Warshaw DM. Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor. Circ Res. 2012 Jul 20; 111(3):375-85.
Score: 0.006
-
Wang H, Haeger SM, Kloxin AM, Leinwand LA, Anseth KS. Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One. 2012; 7(7):e39969.
Score: 0.006
-
Kraft R, Kadyk L, Leinwand LA. Sequence organization of variant mouse 4.5 S RNA genes and pseudogenes. Genomics. 1992 Mar; 12(3):555-66.
Score: 0.006
-
Buttrick PM, Kass A, Kitsis RN, Kaplan ML, Leinwand LA. Behavior of genes directly injected into the rat heart in vivo. Circ Res. 1992 Jan; 70(1):193-8.
Score: 0.006
-
Kitsis RN, Leinwand LA. Discordance between gene regulation in vitro and in vivo. Gene Expr. 1992; 2(4):313-8.
Score: 0.006
-
Kitsis RN, Buttrick PM, McNally EM, Kaplan ML, Leinwand LA. Hormonal modulation of a gene injected into rat heart in vivo. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4138-42.
Score: 0.005
-
McNally EM, Bravo-Zehnder MM, Leinwand LA. Identification of sequences necessary for the association of cardiac myosin subunits. J Cell Biol. 1991 May; 113(3):585-90.
Score: 0.005
-
Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol. 2011 Jul; 51(1):41-50.
Score: 0.005
-
Fishman GI, Hertzberg EL, Spray DC, Leinwand LA. Expression of connexin43 in the developing rat heart. Circ Res. 1991 Mar; 68(3):782-7.
Score: 0.005
-
McNally E, Sohn R, Frankel S, Leinwand L. Expression of myosin and actin in Escherichia coli. Methods Enzymol. 1991; 196:368-89.
Score: 0.005
-
Frankel S, Condeelis J, Leinwand L. Expression of actin in Escherichia coli. Aggregation, solubilization, and functional analysis. J Biol Chem. 1990 Oct 15; 265(29):17980-7.
Score: 0.005
-
Fishman GI, Spray DC, Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol. 1990 Aug; 111(2):589-98.
Score: 0.005
-
Karsch-Mizrachi I, Feghali R, Shows TB, Leinwand LA. Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA. Gene. 1990 May 14; 89(2):289-94.
Score: 0.005
-
Rovner AS, McNally EM, Leinwand LA. Complete cDNA sequence of rat atrial myosin light chain 1: patterns of expression during development and with hypertension. Nucleic Acids Res. 1990 Mar 25; 18(6):1581-6.
Score: 0.005
-
McNally EM, Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences. J Mol Biol. 1989 Dec 05; 210(3):665-71.
Score: 0.005
-
Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. Insights into human beta-cardiac myosin function from single molecule and single cell studies. J Cardiovasc Transl Res. 2009 Dec; 2(4):426-40.
Score: 0.005
-
McNally EM, Gianola KM, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat alpha cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7527-8.
Score: 0.005
-
Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain. Nucleic Acids Res. 1989 Sep 25; 17(18):7529-30.
Score: 0.005
-
Benton JA, Kern HB, Leinwand LA, Mariner PD, Anseth KS. Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11):1950-7.
Score: 0.005
-
Karsch-Mizrachi I, Travis M, Blau H, Leinwand LA. Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene. Nucleic Acids Res. 1989 Aug 11; 17(15):6167-79.
Score: 0.005
-
Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, Falke JJ, Leinwand LA, Maier SF, Yin H, Rice KC, Watkins LR. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun. 2010 Jan; 24(1):83-95.
Score: 0.005
-
Sloane E, Langer S, Jekich B, Mahoney J, Hughes T, Frank M, Seibert W, Huberty G, Coats B, Harrison J, Klinman D, Poole S, Maier S, Johnson K, Chavez R, Watkins LR, Leinwand L, Milligan E. Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain. Gene Ther. 2009 Oct; 16(10):1210-22.
Score: 0.005
-
Feghali R, Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J Cell Biol. 1989 May; 108(5):1791-7.
Score: 0.005
-
McNally EM, Buttrick PM, Leinwand LA. Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension. Nucleic Acids Res. 1989 Apr 11; 17(7):2753-67.
Score: 0.005
-
Leinwand LA, Sohn R, Frankel SA, Goodwin EB, McNally EM. Bacterial expression of eukaryotic contractile proteins. Cell Motil Cytoskeleton. 1989; 14(1):3-11.
Score: 0.005
-
Sloane E, Ledeboer A, Seibert W, Coats B, van Strien M, Maier SF, Johnson KW, Chavez R, Watkins LR, Leinwand L, Milligan ED, Van Dam AM. Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy. Brain Behav Immun. 2009 Jan; 23(1):92-100.
Score: 0.004
-
Heller DL, Gianola KM, Leinwand LA. A highly conserved mouse gene with a propensity to form pseudogenes in mammals. Mol Cell Biol. 1988 Jul; 8(7):2797-803.
Score: 0.004
-
Jensen DR, Knaub LA, Konhilas JP, Leinwand LA, MacLean PS, Eckel RH. Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype? J Lipid Res. 2008 Apr; 49(4):870-9.
Score: 0.004
-
Goodwin EB, Szent-Gyorgyi AG, Leinwand LA. Cloning and characterization of the scallop essential and regulatory myosin light chain cDNAs. J Biol Chem. 1987 Aug 15; 262(23):11052-6.
Score: 0.004
-
Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H246-59.
Score: 0.004
-
Ledeboer A, Jekich BM, Sloane EM, Mahoney JH, Langer SJ, Milligan ED, Martin D, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR. Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun. 2007 Jul; 21(5):686-98.
Score: 0.004
-
Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, Watkins LR. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 2006 Dec 15; 126(1-3):294-308.
Score: 0.004
-
Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. PLoS Genet. 2006 Sep 29; 2(9):e156.
Score: 0.004
-
Dennehey BK, Leinwand LA, Krauter KS. Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts. J Muscle Res Cell Motil. 2006; 27(8):559-75.
Score: 0.004
-
Saez L, Leinwand LA. Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle. Nucleic Acids Res. 1986 Apr 11; 14(7):2951-69.
Score: 0.004
-
Sucharov CC, Mariner PD, Nunley KR, Long C, Leinwand L, Bristow MR. A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction. Am J Physiol Heart Circ Physiol. 2006 Sep; 291(3):H1299-308.
Score: 0.004
-
DeLozanne A, Lewis M, Spudich JA, Leinwand LA. Cloning and characterization of a nonmuscle myosin heavy chain cDNA. Proc Natl Acad Sci U S A. 1985 Oct; 82(20):6807-10.
Score: 0.004
-
Cushing MC, Jaeggli MP, Masters KS, Leinwand LA, Anseth KS. Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells. J Biomed Mater Res A. 2005 Oct 01; 75(1):232-41.
Score: 0.004
-
Paulson KE, Deka N, Schmid CW, Misra R, Schindler CW, Rush MG, Kadyk L, Leinwand L. A transposon-like element in human DNA. Nature. 1985 Jul 25-31; 316(6026):359-61.
Score: 0.004
-
Jackson M, Heller D, Leinwand L. Transcriptional measurements of mouse repeated DNA sequences. Nucleic Acids Res. 1985 May 10; 13(9):3389-403.
Score: 0.004
-
Masters KS, Shah DN, Leinwand LA, Anseth KS. Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials. 2005 May; 26(15):2517-25.
Score: 0.004
-
Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci. 2005 Apr; 21(8):2136-48.
Score: 0.003
-
Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain. 2005 Feb 25; 1:9.
Score: 0.003
-
Masters KS, Shah DN, Walker G, Leinwand LA, Anseth KS. Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J Biomed Mater Res A. 2004 Oct 01; 71(1):172-80.
Score: 0.003
-
Johnston IN, Milligan ED, Wieseler-Frank J, Frank MG, Zapata V, Campisi J, Langer S, Martin D, Green P, Fleshner M, Leinwand L, Maier SF, Watkins LR. A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci. 2004 Aug 18; 24(33):7353-65.
Score: 0.003
-
Stelzer JE, Patel JR, Olsson MC, Fitzsimons DP, Leinwand LA, Moss RL. Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium. Am J Physiol Heart Circ Physiol. 2004 Oct; 287(4):H1756-61.
Score: 0.003
-
Sun L, Paulson KE, Schmid CW, Kadyk L, Leinwand L. Non-Alu family interspersed repeats in human DNA and their transcriptional activity. Nucleic Acids Res. 1984 Mar 26; 12(6):2669-90.
Score: 0.003
-
Heller D, Jackson M, Leinwand L. Organization and expression of non-Alu family interspersed repetitive DNA sequences in the mouse genome. J Mol Biol. 1984 Mar 15; 173(4):419-36.
Score: 0.003
-
Olsson MC, Palmer BM, Stauffer BL, Leinwand LA, Moore RL. Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy. Circ Res. 2004 Feb 06; 94(2):201-7.
Score: 0.003
-
Leinwand LA, Fournier RE, Nadal-Ginard B, Shows TB. Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. Science. 1983 Aug 19; 221(4612):766-9.
Score: 0.003
-
Leinwand LA, Saez L, McNally E, Nadal-Ginard B. Isolation and characterization of human myosin heavy chain genes. Proc Natl Acad Sci U S A. 1983 Jun; 80(12):3716-20.
Score: 0.003
-
Weisbart RH, Yang F, Chan G, Wakelin R, Ferreri K, Zack DJ, Harrison B, Leinwand LA, Cole GM. Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb. Mol Immunol. 2003 Mar; 39(13):783-9.
Score: 0.003
-
Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW. Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cell Motil Cytoskeleton. 2003 Feb; 54(2):105-21.
Score: 0.003
-
Leinwand LA, Wydro RM, Nadal-Ginard B. Small RNA molecules related to the Alu family of repetitive DNA sequences. Mol Cell Biol. 1982 Nov; 2(11):1320-30.
Score: 0.003
-
Pease LR, Nathenson SG, Leinwand LA. Mapping class I gene sequences in the major histocompatibility complex. Nature. 1982 Jul 22; 298(5872):382-5.
Score: 0.003
-
Olsson MC, Palmer BM, Leinwand LA, Moore RL. Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2001 Mar; 280(3):H1136-44.
Score: 0.003
-
S?billon P, Bonne G, Flavigny J, Venin S, Rouche A, Fiszman M, Vikstrom K, Leinwand L, Carrier L, Schwartz K. COOH-terminal truncated human cardiac MyBP-C alters myosin filament organization. C R Acad Sci III. 2001 Mar; 324(3):251-60.
Score: 0.003
-
Chandra M, Rundell VL, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H705-13.
Score: 0.003
-
Carnes J, Frolova L, Zinnen S, Drugeon G, Phillippe M, Justesen J, Haenni AL, Leinwand L, Kisselev LL, Yarus M. Suppression of eukaryotic translation termination by selected RNAs. RNA. 2000 Oct; 6(10):1468-79.
Score: 0.003
-
Lu BD, Allen DL, Leinwand LA, Lyons GE. Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 01; 216(1):312-26.
Score: 0.002
-
Weiss A, McDonough D, Wertman B, Acakpo-Satchivi L, Montgomery K, Kucherlapati R, Leinwand L, Krauter K. Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2958-63.
Score: 0.002
-
Leinwand L, Nichols E, Ruddle FH. Assignment of the gene for glyoxylase I to mouse chromosome 17 by somatic cell genetics. Biochem Genet. 1978 Aug; 16(7-8):659-66.
Score: 0.002
-
Leinwand LA, Ruddle FH. Assignment of the gene for dipeptidase 2 to Mus musculus chromosome 18 by somatic cell hybridization. Biochem Genet. 1978 Jun; 16(5-6):477-84.
Score: 0.002
-
Leinwand LA, Kozak CA, Ruddle FH. Assignment of the genes for triose phosphate isomerase to chromosome 6 and tripeptidase-1 to chromosome 10 in Mus musculus by somatic cell hybridization. Somatic Cell Genet. 1978 Mar; 4(2):233-40.
Score: 0.002
-
Leinwand L, Fournier RE, Nichols EA, Ruddle FH. Assignment of the gene for adenosine kinase to chromosome 14 in Mus musculus by somatic cell hybridization. Cytogenet Cell Genet. 1978; 21(1-2):77-85.
Score: 0.002
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Acakpo-Satchivi LJ, Edelmann W, Sartorius C, Lu BD, Wahr PA, Watkins SC, Metzger JM, Leinwand L, Kucherlapati R. Growth and muscle defects in mice lacking adult myosin heavy chain genes. J Cell Biol. 1997 Dec 01; 139(5):1219-29.
Score: 0.002
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von Harsdorf R, Edwards JG, Shen YT, Kudej RK, Dietz R, Leinwand LA, Nadal-Ginard B, Vatner SF. Identification of a cis-acting regulatory element conferring inducibility of the atrial natriuretic factor gene in acute pressure overload. J Clin Invest. 1997 Sep 01; 100(5):1294-304.
Score: 0.002
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Siri FM, Jelicks LA, Leinwand LA, Gardin JM. Gated magnetic resonance imaging of normal and hypertrophied murine hearts. Am J Physiol. 1997 May; 272(5 Pt 2):H2394-402.
Score: 0.002
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Cohn JN, Bristow MR, Chien KR, Colucci WS, Frazier OH, Leinwand LA, Lorell BH, Moss AJ, Sonnenblick EH, Walsh RA, Mockrin SC, Reinlib L. Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation. 1997 Feb 18; 95(4):766-70.
Score: 0.002
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Li K, Zhang J, Buvoli M, Yan XD, Leinwand L, He H. Ochre suppressor transfer RNA restored dystrophin expression in mdx mice. Life Sci. 1997; 61(15):PL 205-9.
Score: 0.002
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Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol. 1996 Apr; 70(4):2116-23.
Score: 0.002
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Kass-Eisler A, Leinwand L, Gall J, Bloom B, Falck-Pedersen E. Circumventing the immune response to adenovirus-mediated gene therapy. Gene Ther. 1996 Feb; 3(2):154-62.
Score: 0.002
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Liao L, Sindhwani R, Rojkind M, Factor S, Leinwand L, Diamond B. Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity. J Exp Med. 1995 Mar 01; 181(3):1123-31.
Score: 0.002
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Smerdu V, Karsch-Mizrachi I, Campione M, Leinwand L, Schiaffino S. Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle. Am J Physiol. 1994 Dec; 267(6 Pt 1):C1723-8.
Score: 0.002
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Cho M, Hughes SM, Karsch-Mizrachi I, Travis M, Leinwand LA, Blau HM. Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception. J Cell Sci. 1994 Sep; 107 ( Pt 9):2361-71.
Score: 0.002
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Kaplan ML, Cheslow Y, Vikstrom K, Malhotra A, Geenen DL, Nakouzi A, Leinwand LA, Buttrick PM. Cardiac adaptations to chronic exercise in mice. Am J Physiol. 1994 Sep; 267(3 Pt 2):H1167-73.
Score: 0.002
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Sweeney HL, Straceski AJ, Leinwand LA, Tikunov BA, Faust L. Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction. J Biol Chem. 1994 Jan 21; 269(3):1603-5.
Score: 0.002
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Buttrick PM, Kaplan M, Leinwand LA, Scheuer J. Alterations in gene expression in the rat heart after chronic pathological and physiological loads. J Mol Cell Cardiol. 1994 Jan; 26(1):61-7.
Score: 0.002
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Liao L, Sindhwani R, Leinwand L, Diamond B, Factor S. Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes. J Clin Invest. 1993 Dec; 92(6):2877-82.
Score: 0.002
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Hughes SM, Cho M, Karsch-Mizrachi I, Travis M, Silberstein L, Leinwand LA, Blau HM. Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle. Dev Biol. 1993 Jul; 158(1):183-99.
Score: 0.002
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Ogata I, S?ez CG, Greenwel P, Ponce Mde L, Geerts A, Leinwand LA, Rojkind M. Rat liver fat-storing cell lines express sarcomeric myosin heavy chain mRNA and protein. Cell Motil Cytoskeleton. 1993; 26(2):125-32.
Score: 0.001
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Nadal-Ginard B, Leinwand LA, Libby P, Schwartz K, Strauss HC, Vatner SF. Cellular and molecular biology of the cardiovascular system. Circ Res. 1992 Jul; 71(1):1-2.
Score: 0.001
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Buttrick P, Malhotra A, Factor S, Greenen D, Leinwand L, Scheuer J. Effect of aging and hypertension on myosin biochemistry and gene expression in the rat heart. Circ Res. 1991 Mar; 68(3):645-52.
Score: 0.001
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Goodwin EB, Leinwand LA, Szent-Gy?rgyi AG. Regulation of scallop myosin by mutant regulatory light chains. J Mol Biol. 1990 Nov 05; 216(1):85-93.
Score: 0.001
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Tsika RW, Bahl JJ, Leinwand LA, Morkin E. Thyroid hormone regulates expression of a transfected human alpha-myosin heavy-chain fusion gene in fetal rat heart cells. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):379-83.
Score: 0.001
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Eghbali M, Blumenfeld OO, Seifter S, Buttrick PM, Leinwand LA, Robinson TF, Zern MA, Giambrone MA. Localization of types I, III and IV collagen mRNAs in rat heart cells by in situ hybridization. J Mol Cell Cardiol. 1989 Jan; 21(1):103-13.
Score: 0.001
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Warrick HM, De Lozanne A, Leinwand LA, Spudich JA. Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1986 Dec; 83(24):9433-7.
Score: 0.001
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Goodenow M, Kessler K, Leinwand L, Lilly F. Absence of trisomy 15 in chemically induced murine T-cell lymphomas. Cancer Genet Cytogenet. 1986 Jan 15; 19(3-4):205-11.
Score: 0.001
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Chinsky J, Goodenow MM, Jackson M, Lilly F, Leinwand L, Childs G. Comparison of endogenous murine leukemia virus proviral organization and RNA expression in 3-methylcholanthrene-induced and spontaneous thymic lymphomas in RF and AKR mice. J Virol. 1985 Jan; 53(1):94-9.
Score: 0.001
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Enat R, Jefferson DM, Ruiz-Opazo N, Gatmaitan Z, Leinwand LA, Reid LM. Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix. Proc Natl Acad Sci U S A. 1984 Mar; 81(5):1411-5.
Score: 0.001
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Gatmaitan Z, Jefferson DM, Ruiz-Opazo N, Biempica L, Arias IM, Dudas G, Leinwand LA, Reid LM. Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata. J Cell Biol. 1983 Oct; 97(4):1179-90.
Score: 0.001
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Krauter K, Leinwand L, D'Eustachio P, Ruddle F, Darnell JE. Structural genes of the mouse major urinary protein are on chromosome 4. J Cell Biol. 1982 Aug; 94(2):414-7.
Score: 0.001
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Haynes SR, Toomey TP, Leinwand L, Jelinek WR. The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element. Mol Cell Biol. 1981 Jul; 1(7):573-83.
Score: 0.001
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Jelinek WR, Toomey TP, Leinwand L, Duncan CH, Biro PA, Choudary PV, Weissman SM, Rubin CM, Houck CM, Deininger PL, Schmid CW. Ubiquitous, interspersed repeated sequences in mammalian genomes. Proc Natl Acad Sci U S A. 1980 Mar; 77(3):1398-402.
Score: 0.001
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Swan D, D'Eustachio P, Leinwand L, Seidman J, Keithley D, Ruddle FH. Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A. 1979 Jun; 76(6):2735-9.
Score: 0.001
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Kozak CA, Fournier RE, Leinwand LA, Ruddle FH. Assignment of the gene governing cellular ouabain resistance to Mus musculus chromosome 3 using human/mouse microcell hybrids. Biochem Genet. 1979 Feb; 17(1-2):23-34.
Score: 0.001
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Ruddle NH, Conta BS, Leinwand L, Kozak C, Ruddle F, Besmer P, Baltimore D. Assignment of the receptor for ecotropic murine leukemia virus to mouse chromosome 5. J Exp Med. 1978 Aug 01; 148(2):451-65.
Score: 0.001
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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