 Connection
Leslie Leinwand to Humans
This is a "connection" page, showing publications Leslie Leinwand has written about Humans.
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Martin TG, Leinwand LA. Hearts apart: sex differences in cardiac remodeling in health and disease. J Clin Invest. 2024 Jul 01; 134(13).
Score: 0.023
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Buvoli M, Wilson GC, Buvoli A, Gugel JF, Hau A, B?nnemann CG, Paradas C, Ryba DM, Woulfe KC, Walker LA, Buvoli T, Ochala J, Leinwand LA. A Laing distal myopathy-associated proline substitution in the ?-myosin rod perturbs myosin cross-bridging activity. J Clin Invest. 2024 May 01; 134(9).
Score: 0.023
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Liu C, Karabina A, Meller A, Bhattacharjee A, Agostino CJ, Bowman GR, Ruppel KM, Spudich JA, Leinwand LA. Homologous mutations in human ?, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proc Natl Acad Sci U S A. 2024 Feb 27; 121(9):e2315472121.
Score: 0.023
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Lee LA, Barrick SK, Buvoli AE, Walklate J, Stump WT, Geeves M, Greenberg MJ, Leinwand LA. Distinct effects of two hearing loss-associated mutations in?the sarcomeric myosin MYH7b. J Biol Chem. 2023 05; 299(5):104631.
Score: 0.021
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Gotthardt M, Badillo-Lisakowski V, Parikh VN, Ashley E, Furtado M, Carmo-Fonseca M, Schudy S, Meder B, Grosch M, Steinmetz L, Crocini C, Leinwand L. Cardiac splicing as a diagnostic and therapeutic target. Nat Rev Cardiol. 2023 08; 20(8):517-530.
Score: 0.021
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Lee LA, Barrick SK, Meller A, Walklate J, Lotthammer JM, Tay JW, Stump WT, Bowman G, Geeves MA, Greenberg MJ, Leinwand LA. Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles. J Biol Chem. 2023 01; 299(1):102657.
Score: 0.021
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Magida JA, Tan Y, Wall CE, Harrison BC, Marr TG, Peter AK, Riquelme CA, Leinwand LA. Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage. J Gen Physiol. 2022 04 04; 154(4).
Score: 0.020
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Lehman SJ, Crocini C, Leinwand LA. Targeting the sarcomere in inherited cardiomyopathies. Nat Rev Cardiol. 2022 06; 19(6):353-363.
Score: 0.020
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Lee LA, Broadwell LJ, Buvoli M, Leinwand LA. Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart. J Am Heart Assoc. 2021 07 20; 10(14):e020965.
Score: 0.019
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Walker CJ, Schroeder ME, Aguado BA, Anseth KS, Leinwand LA. Matters of the heart: Cellular sex differences. J Mol Cell Cardiol. 2021 11; 160:42-55.
Score: 0.019
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Broadwell LJ, Smallegan MJ, Rigby KM, Navarro-Arriola JS, Montgomery RL, Rinn JL, Leinwand LA. Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart. J Biol Chem. 2021 Jan-Jun; 296:100694.
Score: 0.019
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Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. J Biol Chem. 2019 11 15; 294(46):17451-17462.
Score: 0.017
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Lee LA, Karabina A, Broadwell LJ, Leinwand LA. The ancient sarcomeric myosins found in specialized muscles. Skelet Muscle. 2019 03 05; 9(1):7.
Score: 0.016
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Ujfalusi Z, Vera CD, Mijailovich SM, Svicevic M, Yu EC, Kawana M, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. J Biol Chem. 2018 06 08; 293(23):9017-9029.
Score: 0.015
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Peter AK, Crocini C, Leinwand LA. Expanding our scientific horizons: utilization of unique model organisms in biological research. EMBO J. 2017 08 15; 36(16):2311-2314.
Score: 0.014
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Vega RB, Konhilas JP, Kelly DP, Leinwand LA. Molecular Mechanisms Underlying Cardiac Adaptation to Exercise. Cell Metab. 2017 May 02; 25(5):1012-1026.
Score: 0.014
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Peter AK, Bjerke MA, Leinwand LA. Biology of the cardiac myocyte in heart disease. Mol Biol Cell. 2016 07 15; 27(14):2149-60.
Score: 0.014
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Pugach EK, Blenck CL, Dragavon JM, Langer SJ, Leinwand LA. Estrogen receptor profiling and activity in cardiac myocytes. Mol Cell Endocrinol. 2016 08 15; 431:62-70.
Score: 0.013
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Blenck CL, Harvey PA, Reckelhoff JF, Leinwand LA. The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circ Res. 2016 Apr 15; 118(8):1294-312.
Score: 0.013
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Walklate J, Vera C, Bloemink MJ, Geeves MA, Leinwand L. The Most Prevalent Freeman-Sheldon Syndrome Mutations in the Embryonic Myosin Motor Share Functional Defects. J Biol Chem. 2016 May 06; 291(19):10318-31.
Score: 0.013
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Pugach EK, Richmond PA, Azofeifa JG, Dowell RD, Leinwand LA. Prolonged Cre expression driven by the a-myosin heavy chain promoter can be cardiotoxic. J Mol Cell Cardiol. 2015 Sep; 86:54-61.
Score: 0.013
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Guess MG, Barthel KK, Harrison BC, Leinwand LA. miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One. 2015; 10(2):e0118229.
Score: 0.012
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Haizlip KM, Harrison BC, Leinwand LA. Sex-based differences in skeletal muscle kinetics and fiber-type composition. Physiology (Bethesda). 2015 Jan; 30(1):30-9.
Score: 0.012
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Chung E, Leinwand LA. Pregnancy as a cardiac stress model. Cardiovasc Res. 2014 Mar 15; 101(4):561-70.
Score: 0.011
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Yeung F, Chung E, Guess MG, Bell ML, Leinwand LA. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 2012 Aug; 40(15):7303-18.
Score: 0.010
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Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Identification of functional differences between recombinant human a and ? cardiac myosin motors. Cell Mol Life Sci. 2012 07; 69(13):2261-77.
Score: 0.010
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Buvoli M, Buvoli A, Leinwand LA. Effects of pathogenic proline mutations on myosin assembly. J Mol Biol. 2012 Feb 03; 415(5):807-18.
Score: 0.010
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Harvey PA, Leinwand LA. The cell biology of disease: cellular mechanisms of cardiomyopathy. J Cell Biol. 2011 Aug 08; 194(3):355-65.
Score: 0.010
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Leinwand LA, Moss RL. Medicine. Chemically tuned myosin motors. Science. 2011 Mar 18; 331(6023):1392-3.
Score: 0.009
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Wall CE, Cozza S, Riquelme CA, McCombie WR, Heimiller JK, Marr TG, Leinwand LA. Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation. Physiol Genomics. 2011 Jan 01; 43(2):69-76.
Score: 0.009
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Bell ML, Buvoli M, Leinwand LA. Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Mol Cell Biol. 2010 Apr; 30(8):1937-45.
Score: 0.009
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Bhupathy P, Haines CD, Leinwand LA. Influence of sex hormones and phytoestrogens on heart disease in men and women. Womens Health (Lond). 2010 Jan; 6(1):77-95.
Score: 0.009
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Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1053-8.
Score: 0.009
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Armel TZ, Leinwand LA. A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype. Biochem Biophys Res Commun. 2010 Jan 01; 391(1):352-6.
Score: 0.009
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Armel TZ, Leinwand LA. Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes. J Mol Cell Cardiol. 2010 May; 48(5):1007-13.
Score: 0.008
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Hughes TS, Langer SJ, Virtanen SI, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. J Gene Med. 2009 Sep; 11(9):782-90.
Score: 0.008
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Luczak ED, Leinwand LA. Sex-based cardiac physiology. Annu Rev Physiol. 2009; 71:1-18.
Score: 0.008
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Chung E, Leinwand LA. Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins. Circ Res. 2008 Dec 05; 103(12):1351-3.
Score: 0.008
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Hughes TS, Langer SJ, Johnson KW, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Mol Ther. 2009 Jan; 17(1):88-94.
Score: 0.008
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Konhilas JP, Leinwand LA. The effects of biological sex and diet on the development of heart failure. Circulation. 2007 Dec 04; 116(23):2747-59.
Score: 0.007
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Leinwand LA. Molecular events underlying pregnancy-induced cardiomyopathy. Cell. 2007 Feb 09; 128(3):437-8.
Score: 0.007
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Sucharov CC, Langer S, Bristow M, Leinwand L. Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C1029-37.
Score: 0.007
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Beylkin DH, Allen DL, Leinwand LA. MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes. Dev Biol. 2006 Jun 15; 294(2):541-53.
Score: 0.007
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Leinwand LA. Hope for a broken heart? Cell. 2003 Sep 19; 114(6):658-9.
Score: 0.006
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Leinwand LA. Sex is a potent modifier of the cardiovascular system. J Clin Invest. 2003 Aug; 112(3):302-7.
Score: 0.006
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Maass AH, Leinwand LA. Mechanisms of the pathogenesis of troponin T-based familial hypertrophic cardiomyopathy. Trends Cardiovasc Med. 2003 Aug; 13(6):232-7.
Score: 0.006
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Sucharov CC, Mariner P, Long C, Bristow M, Leinwand L. Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter. J Biol Chem. 2003 Aug 15; 278(33):31233-9.
Score: 0.005
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Liang Q, Chan YC, Toscano J, Bjorkman KK, Leinwand LA, Parker R, Nozik ES, Nesbitt DJ, Ye J. Breath analysis by ultra-sensitive broadband laser spectroscopy detects SARS-CoV-2 infection. J Breath Res. 2023 04 05; 17(3).
Score: 0.005
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Allen DL, Leinwand LA. Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter. J Biol Chem. 2002 Nov 22; 277(47):45323-30.
Score: 0.005
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Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Circulation. 2022 08 30; 146(9):699-714.
Score: 0.005
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Langer SJ, Ghafoori AP, Byrd M, Leinwand L. A genetic screen identifies novel non-compatible loxP sites. Nucleic Acids Res. 2002 Jul 15; 30(14):3067-77.
Score: 0.005
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Buvoli M, Langer SJ, Bialik S, Leinwand LA. Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors. Gene Ther. 2002 Feb; 9(3):227-31.
Score: 0.005
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Aguado BA, Walker CJ, Grim JC, Schroeder ME, Batan D, Vogt BJ, Rodriguez AG, Schwisow JA, Moulton KS, Weiss RM, Heistad DD, Leinwand LA, Anseth KS. Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts. Circulation. 2022 02 15; 145(7):513-530.
Score: 0.005
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Maass A, Konhilas JP, Stauffer BL, Leinwand LA. From sarcomeric mutations to heart disease: understanding familial hypertrophic cardiomyopathy. Cold Spring Harb Symp Quant Biol. 2002; 67:409-15.
Score: 0.005
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Bjorkman KK, Saldi TK, Lasda E, Bauer LC, Kovarik J, Gonzales PK, Fink MR, Tat KL, Hager CR, Davis JC, Ozeroff CD, Brisson GR, Larremore DB, Leinwand LA, McQueen MB, Parker R. Higher Viral Load Drives Infrequent Severe Acute Respiratory Syndrome Coronavirus 2 Transmission Between Asymptomatic Residence Hall Roommates. J Infect Dis. 2021 10 28; 224(8):1316-1324.
Score: 0.005
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Reeves K, Liebig J, Feula A, Saldi T, Lasda E, Johnson W, Lilienfeld J, Maggi J, Pulley K, Wilkerson PJ, Real B, Zak G, Davis J, Fink M, Gonzales P, Hager C, Ozeroff C, Tat K, Alkire M, Butler C, Coe E, Darby J, Freeman N, Heuer H, Jones JR, Karr M, Key S, Maxwell K, Nelson L, Saldana E, Shea R, Salveson L, Tomlinson K, Vargas-Barriga J, Vigil B, Brisson G, Parker R, Leinwand LA, Bjorkman K, Mansfeldt C. High-resolution within-sewer SARS-CoV-2 surveillance facilitates informed intervention. Water Res. 2021 Oct 01; 204:117613.
Score: 0.005
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Freeman K, Nakao K, Leinwand LA. Low sequence variation in the gene encoding the human beta-myosin heavy chain. Genomics. 2001 Aug; 76(1-3):73-80.
Score: 0.005
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Johnson CA, McGreig JE, Jeanfavre ST, Walklate J, Vera CD, Farr? M, Mulvihill DP, Baines AJ, Ridout M, Leinwand LA, Wass MN, Geeves MA. Identification of sequence changes in myosin II that adjust muscle contraction velocity. PLoS Biol. 2021 06; 19(6):e3001248.
Score: 0.005
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Yang Q, Saldi TK, Gonzales PK, Lasda E, Decker CJ, Tat KL, Fink MR, Hager CR, Davis JC, Ozeroff CD, Muhlrad D, Clark SK, Fattor WT, Meyerson NR, Paige CL, Gilchrist AR, Barbachano-Guerrero A, Worden-Sapper ER, Wu SS, Brisson GR, McQueen MB, Dowell RD, Leinwand L, Parker R, Sawyer SL. Just 2% of SARS-CoV-2-positive individuals carry 90% of the virus circulating in communities. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
Score: 0.005
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Maass A, Leinwand LA. A role for calreticulin in the adult heart? J Clin Invest. 2001 May; 107(10):1223-5.
Score: 0.005
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Walker CJ, Crocini C, Ramirez D, Killaars AR, Grim JC, Aguado BA, Clark K, Allen MA, Dowell RD, Leinwand LA, Anseth KS. Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts. Nat Biomed Eng. 2021 12; 5(12):1485-1499.
Score: 0.005
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Yang Q, Meyerson NR, Clark SK, Paige CL, Fattor WT, Gilchrist AR, Barbachano-Guerrero A, Healy BG, Worden-Sapper ER, Wu SS, Muhlrad D, Decker CJ, Saldi TK, Lasda E, Gonzales P, Fink MR, Tat KL, Hager CR, Davis JC, Ozeroff CD, Brisson GR, McQueen MB, Leinwand LA, Parker R, Sawyer SL. Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers. Elife. 2021 03 29; 10.
Score: 0.005
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Leinwand LA. Calcineurin inhibition and cardiac hypertrophy: a matter of balance. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):2947-9.
Score: 0.005
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Walker GA, Guerrero IA, Leinwand LA. Myofibroblasts: molecular crossdressers. Curr Top Dev Biol. 2001; 51:91-107.
Score: 0.005
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Lakdawala NK, Olivotto I, Day SM, Han L, Ashley EA, Michels M, Ingles J, Semsarian C, Jacoby D, Jefferies JL, Colan SD, Pereira AC, Rossano JW, Wittekind S, Ware JS, Saberi S, Helms AS, Cirino AL, Leinwand LA, Seidman CE, Ho CY. Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2021 02; 14(1):e003062.
Score: 0.005
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Buvoli A, Buvoli M, Leinwand LA. Enhanced detection of tRNA isoacceptors by combinatorial oligonucleotide hybridization. RNA. 2000 Jun; 6(6):912-8.
Score: 0.004
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Maass A, Leinwand LA. Animal models of hypertrophic cardiomyopathy. Curr Opin Cardiol. 2000 May; 15(3):189-96.
Score: 0.004
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Miyata S, Minobe W, Bristow MR, Leinwand LA. Myosin heavy chain isoform expression in the failing and nonfailing human heart. Circ Res. 2000 Mar 03; 86(4):386-90.
Score: 0.004
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I?igo MR, Amorese AJ, Tarpey MD, Balestrieri NP, Jones KG, Patteson DJ, Jackson KC, Torres MJ, Lin CT, Smith CD, Heden TD, McMillin SL, Weyrauch LA, Stanley EC, Schmidt CA, Kilburg-Basnyat BB, Reece SW, Psaltis CE, Leinwand LA, Funai K, McClung JM, Gowdy KM, Witczak CA, Lowe DA, Neufer PD, Spangenburg EE. Estrogen receptor-a in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation. Mol Metab. 2020 04; 34:1-15.
Score: 0.004
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Aguado BA, Schuetze KB, Grim JC, Walker CJ, Cox AC, Ceccato TL, Tan AC, Sucharov CC, Leinwand LA, Taylor MRG, McKinsey TA, Anseth KS. Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation. Sci Transl Med. 2019 09 11; 11(509).
Score: 0.004
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Johnson CA, Walklate J, Svicevic M, Mijailovich SM, Vera C, Karabina A, Leinwand LA, Geeves MA. The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles. J Biol Chem. 2019 09 27; 294(39):14267-14278.
Score: 0.004
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Tardiff JC, Hewett TE, Palmer BM, Olsson C, Factor SM, Moore RL, Robbins J, Leinwand LA. Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. J Clin Invest. 1999 Aug; 104(4):469-81.
Score: 0.004
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Weiss A, Schiaffino S, Leinwand LA. Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity. J Mol Biol. 1999 Jul 02; 290(1):61-75.
Score: 0.004
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G?nay KA, Ceccato TL, Silver JS, Bannister KL, Bednarski OJ, Leinwand LA, Anseth KS. PEG-Anthracene Hydrogels as an On-Demand Stiffening Matrix To Study Mechanobiology. Angew Chem Int Ed Engl. 2019 07 15; 58(29):9912-9916.
Score: 0.004
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Roopnarine O, Leinwand LA. Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy. Biophys J. 1998 Dec; 75(6):3023-30.
Score: 0.004
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Tardiff JC, Factor SM, Tompkins BD, Hewett TE, Palmer BM, Moore RL, Schwartz S, Robbins J, Leinwand LA. A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J Clin Invest. 1998 Jun 15; 101(12):2800-11.
Score: 0.004
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Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O'Rourke B, Aon MA, Abraham MR. Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models. JCI Insight. 2018 03 22; 3(6).
Score: 0.004
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Nakao K, Minobe W, Roden R, Bristow MR, Leinwand LA. Myosin heavy chain gene expression in human heart failure. J Clin Invest. 1997 Nov 01; 100(9):2362-70.
Score: 0.004
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Sohn RL, Vikstrom KL, Strauss M, Cohen C, Szent-Gyorgyi AG, Leinwand LA. A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. J Mol Biol. 1997 Feb 21; 266(2):317-30.
Score: 0.004
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Vikstrom KL, Seiler SH, Sohn RL, Strauss M, Weiss A, Welikson RE, Leinwand LA. The vertebrate myosin heavy chain: genetics and assembly properties. Cell Struct Funct. 1997 Feb; 22(1):123-9.
Score: 0.004
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Li K, Buvoli M, Welikson RE, Vikstrom KL, Leinwand LA. Advances in cardiovascular gene transfer. Cardiologia. 1997 Jan; 42(1):39-46.
Score: 0.003
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Kass-Eisler A, Leinwand LA. DNA- and adenovirus-mediated gene transfer into cardiac muscle. Methods Cell Biol. 1997; 52:423-37.
Score: 0.003
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Schiaffino S, Murgia M, Leinwand LA, Reggiani C. Letter to the editor: Comments on Stuart et al. (2016): "Myosin content of individual human muscle fibers isolated by laser capture microdissection". Am J Physiol Cell Physiol. 2016 12 01; 311(6):C1048-C1049.
Score: 0.003
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Vikstrom KL, Factor SM, Leinwand LA. Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy. Mol Med. 1996 Sep; 2(5):556-67.
Score: 0.003
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Feinstein-Linial M, Buvoli M, Buvoli A, Sadeh M, Dabby R, Straussberg R, Shelef I, Dayan D, Leinwand LA, Birk OS. Two novel MYH7 proline substitutions cause Laing Distal Myopathy-like phenotypes with variable expressivity and neck extensor contracture. BMC Med Genet. 2016 08 12; 17(1):57.
Score: 0.003
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Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 05; 351(6273):617-21.
Score: 0.003
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Vikstrom KL, Leinwand LA. Contractile protein mutations and heart disease. Curr Opin Cell Biol. 1996 Feb; 8(1):97-105.
Score: 0.003
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Weiss A, Leinwand LA. The mammalian myosin heavy chain gene family. Annu Rev Cell Dev Biol. 1996; 12:417-39.
Score: 0.003
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Kass-Eisler A, Li K, Leinwand LA. Prospects for gene therapy with direct injection of polynucleotides. Ann N Y Acad Sci. 1995 Nov 27; 772:232-40.
Score: 0.003
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Taylor KC, Buvoli M, Korkmaz EN, Buvoli A, Zheng Y, Heinze NT, Cui Q, Leinwand LA, Rayment I. Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):E3806-15.
Score: 0.003
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Vikstrom KL, Factor SM, Leinwand LA. A murine model for hypertrophic cardiomyopathy. Z Kardiol. 1995; 84 Suppl 4:49-54.
Score: 0.003
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Wang H, Leinwand LA, Anseth KS. Cardiac valve cells and their microenvironment--insights from in vitro studies. Nat Rev Cardiol. 2014 Dec; 11(12):715-27.
Score: 0.003
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Burns KM, Byrne BJ, Gelb BD, K?hn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL, Taylor MD, Towbin JA, Redington AN. New mechanistic and therapeutic targets for pediatric heart failure: report from a National Heart, Lung, and Blood Institute working group. Circulation. 2014 Jul 01; 130(1):79-86.
Score: 0.003
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Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA. Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):589-93.
Score: 0.003
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Weiss A, Mayer DC, Leinwand LA. Diversity of myosin-based motility: multiple genes and functions. Soc Gen Physiol Ser. 1994; 49:159-71.
Score: 0.003
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Bloemink M, Deacon J, Langer S, Vera C, Combs A, Leinwand L, Geeves MA. The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac ?-myosin. J Biol Chem. 2014 Feb 21; 289(8):5158-67.
Score: 0.003
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Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11498-502.
Score: 0.003
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Bloemink MJ, Deacon JC, Resnicow DI, Leinwand LA, Geeves MA. The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. J Biol Chem. 2013 Sep 20; 288(38):27469-27479.
Score: 0.003
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Wang H, Sridhar B, Leinwand LA, Anseth KS. Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves. PLoS One. 2013; 8(7):e69667.
Score: 0.003
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Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human ?-cardiac myosin motor function. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12607-12.
Score: 0.003
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Yoon SJ, Seiler SH, Kucherlapati R, Leinwand L. Organization of the human skeletal myosin heavy chain gene cluster. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12078-82.
Score: 0.003
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Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM. A PGC-1a isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 2012 Dec 07; 151(6):1319-31.
Score: 0.003
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Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012 Dec 13; 492(7428):285-9.
Score: 0.003
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Spangenburg EE, Geiger PC, Leinwand LA, Lowe DA. Regulation of physiological and metabolic function of muscle by female sex steroids. Med Sci Sports Exerc. 2012 Sep; 44(9):1653-62.
Score: 0.003
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Epstein HF, Fischman DA, Bader D, Changeux JP, Buckhold K, Ordahl CP, Hoffman E, Kedes LH, Konieczny S, Leinwand LA. Myoblast therapy. Science. 1992 Aug 07; 257(5071):738.
Score: 0.003
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Moore JR, Leinwand L, Warshaw DM. Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor. Circ Res. 2012 Jul 20; 111(3):375-85.
Score: 0.003
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Kitsis RN, Leinwand LA. Discordance between gene regulation in vitro and in vivo. Gene Expr. 1992; 2(4):313-8.
Score: 0.002
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Fishman GI, Eddy RL, Shows TB, Rosenthal L, Leinwand LA. The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. Genomics. 1991 May; 10(1):250-6.
Score: 0.002
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Fishman GI, Moreno AP, Spray DC, Leinwand LA. Functional analysis of human cardiac gap junction channel mutants. Proc Natl Acad Sci U S A. 1991 May 01; 88(9):3525-9.
Score: 0.002
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McNally E, Sohn R, Frankel S, Leinwand L. Expression of myosin and actin in Escherichia coli. Methods Enzymol. 1991; 196:368-89.
Score: 0.002
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Fishman GI, Spray DC, Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol. 1990 Aug; 111(2):589-98.
Score: 0.002
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Karsch-Mizrachi I, Feghali R, Shows TB, Leinwand LA. Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA. Gene. 1990 May 14; 89(2):289-94.
Score: 0.002
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Saez CG, Myers JC, Shows TB, Leinwand LA. Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation. Proc Natl Acad Sci U S A. 1990 Feb; 87(3):1164-8.
Score: 0.002
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Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. Insights into human beta-cardiac myosin function from single molecule and single cell studies. J Cardiovasc Transl Res. 2009 Dec; 2(4):426-40.
Score: 0.002
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Karsch-Mizrachi I, Travis M, Blau H, Leinwand LA. Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene. Nucleic Acids Res. 1989 Aug 11; 17(15):6167-79.
Score: 0.002
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Feghali R, Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J Cell Biol. 1989 May; 108(5):1791-7.
Score: 0.002
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McNally EM, Buttrick PM, Leinwand LA. Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension. Nucleic Acids Res. 1989 Apr 11; 17(7):2753-67.
Score: 0.002
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Hamady M, Buvoli M, Leinwand LA, Knight R. Estimate of the abundance of cardiomyopathic mutations in the ?-myosin gene. Int J Cardiol. 2010 Sep 24; 144(1):124-6.
Score: 0.002
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Leinwand LA, Sohn R, Frankel SA, Goodwin EB, McNally EM. Bacterial expression of eukaryotic contractile proteins. Cell Motil Cytoskeleton. 1989; 14(1):3-11.
Score: 0.002
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Buvoli M, Hamady M, Leinwand LA, Knight R. Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations. Trends Cardiovasc Med. 2008 May; 18(4):141-9.
Score: 0.002
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Jensen DR, Knaub LA, Konhilas JP, Leinwand LA, MacLean PS, Eckel RH. Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype? J Lipid Res. 2008 Apr; 49(4):870-9.
Score: 0.002
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Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA. Human cardiac myosin heavy chain genes and their linkage in the genome. Nucleic Acids Res. 1987 Jul 10; 15(13):5443-59.
Score: 0.002
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Benoit DS, Tripodi MC, Blanchette JO, Langer SJ, Leinwand LA, Anseth KS. Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A. 2007 May; 81(2):259-68.
Score: 0.002
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Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, Dupuis J, Long CS, Rubin LJ, Smart FW, Suzuki YJ, Gladwin M, Denholm EM, Gail DB. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation. 2006 Oct 24; 114(17):1883-91.
Score: 0.002
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Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, Watkins LR. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 2006 Dec 15; 126(1-3):294-308.
Score: 0.002
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Saez L, Leinwand LA. Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle. Nucleic Acids Res. 1986 Apr 11; 14(7):2951-69.
Score: 0.002
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Sucharov CC, Mariner PD, Nunley KR, Long C, Leinwand L, Bristow MR. A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction. Am J Physiol Heart Circ Physiol. 2006 Sep; 291(3):H1299-308.
Score: 0.002
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Paulson KE, Deka N, Schmid CW, Misra R, Schindler CW, Rush MG, Kadyk L, Leinwand L. A transposon-like element in human DNA. Nature. 1985 Jul 25-31; 316(6026):359-61.
Score: 0.002
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Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci. 2005 Apr; 21(8):2136-48.
Score: 0.002
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Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain. 2005 Feb 25; 1:9.
Score: 0.002
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Sun L, Paulson KE, Schmid CW, Kadyk L, Leinwand L. Non-Alu family interspersed repeats in human DNA and their transcriptional activity. Nucleic Acids Res. 1984 Mar 26; 12(6):2669-90.
Score: 0.001
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Heller D, Jackson M, Leinwand L. Organization and expression of non-Alu family interspersed repetitive DNA sequences in the mouse genome. J Mol Biol. 1984 Mar 15; 173(4):419-36.
Score: 0.001
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Leinwand LA, Fournier RE, Nadal-Ginard B, Shows TB. Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. Science. 1983 Aug 19; 221(4612):766-9.
Score: 0.001
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Leinwand LA, Saez L, McNally E, Nadal-Ginard B. Isolation and characterization of human myosin heavy chain genes. Proc Natl Acad Sci U S A. 1983 Jun; 80(12):3716-20.
Score: 0.001
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Carnes J, Jacobson M, Leinwand L, Yarus M. Stop codon suppression via inhibition of eRF1 expression. RNA. 2003 Jun; 9(6):648-53.
Score: 0.001
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Loscalzo J, Balaban R, Becker LB, Ginsburg GS, Hachinski VC, Hall JE, Heistad DD, Leinwand LA, Lenfant CJ, Marban E, Olson EN, Schwartz SM. Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report. Circulation. 2002 Nov 12; 106(20):e149-61.
Score: 0.001
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Crystal RG, Bitterman PB, Mossman B, Schwarz MI, Sheppard D, Almasy L, Chapman HA, Friedman SL, King TE, Leinwand LA, Liotta L, Martin GR, Schwartz DA, Schultz GS, Wagner CR, Musson RA. Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med. 2002 Jul 15; 166(2):236-46.
Score: 0.001
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S?billon P, Bonne G, Flavigny J, Venin S, Rouche A, Fiszman M, Vikstrom K, Leinwand L, Carrier L, Schwartz K. COOH-terminal truncated human cardiac MyBP-C alters myosin filament organization. C R Acad Sci III. 2001 Mar; 324(3):251-60.
Score: 0.001
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Chandra M, Rundell VL, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T. Am J Physiol Heart Circ Physiol. 2001 Feb; 280(2):H705-13.
Score: 0.001
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Carnes J, Frolova L, Zinnen S, Drugeon G, Phillippe M, Justesen J, Haenni AL, Leinwand L, Kisselev LL, Yarus M. Suppression of eukaryotic translation termination by selected RNAs. RNA. 2000 Oct; 6(10):1468-79.
Score: 0.001
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Testa M, Ennezat PV, Vikstrom KL, Demopoulos L, Gentilucci M, Loperfido F, Fanelli R, Kitsis RN, Leinwand LA, LeJemtel TH. Modulation of vascular endothelial gene expression by physical training in patients with chronic heart failure. Ital Heart J. 2000 Jun; 1(6):426-30.
Score: 0.001
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Weiss A, McDonough D, Wertman B, Acakpo-Satchivi L, Montgomery K, Kucherlapati R, Leinwand L, Krauter K. Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2958-63.
Score: 0.001
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Cohn JN, Bristow MR, Chien KR, Colucci WS, Frazier OH, Leinwand LA, Lorell BH, Moss AJ, Sonnenblick EH, Walsh RA, Mockrin SC, Reinlib L. Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation. 1997 Feb 18; 95(4):766-70.
Score: 0.001
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Gall J, Kass-Eisler A, Leinwand L, Falck-Pedersen E. Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J Virol. 1996 Apr; 70(4):2116-23.
Score: 0.001
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Smerdu V, Karsch-Mizrachi I, Campione M, Leinwand L, Schiaffino S. Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle. Am J Physiol. 1994 Dec; 267(6 Pt 1):C1723-8.
Score: 0.001
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Cho M, Hughes SM, Karsch-Mizrachi I, Travis M, Leinwand LA, Blau HM. Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception. J Cell Sci. 1994 Sep; 107 ( Pt 9):2361-71.
Score: 0.001
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Sweeney HL, Straceski AJ, Leinwand LA, Tikunov BA, Faust L. Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction. J Biol Chem. 1994 Jan 21; 269(3):1603-5.
Score: 0.001
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Hughes SM, Cho M, Karsch-Mizrachi I, Travis M, Silberstein L, Leinwand LA, Blau HM. Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle. Dev Biol. 1993 Jul; 158(1):183-99.
Score: 0.001
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Feghali R, Karsch-Mizrachi I, Leinwand LA, Kohtz DS. Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture. Gene Expr. 1992; 2(1):49-58.
Score: 0.001
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Tsika RW, Bahl JJ, Leinwand LA, Morkin E. Thyroid hormone regulates expression of a transfected human alpha-myosin heavy-chain fusion gene in fetal rat heart cells. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):379-83.
Score: 0.001
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Deka N, Wong E, Matera AG, Kraft R, Leinwand LA, Schmid CW. Repetitive nucleotide sequence insertions into a novel calmodulin-related gene and its processed pseudogene. Gene. 1988 Nov 15; 71(1):123-34.
Score: 0.000
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Goodenow M, Kessler K, Leinwand L, Lilly F. Absence of trisomy 15 in chemically induced murine T-cell lymphomas. Cancer Genet Cytogenet. 1986 Jan 15; 19(3-4):205-11.
Score: 0.000
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Schwartz CE, McNally E, Leinwand L, Skolnick MH. A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13. Cytogenet Cell Genet. 1986; 43(1-2):117-20.
Score: 0.000
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Haynes SR, Toomey TP, Leinwand L, Jelinek WR. The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element. Mol Cell Biol. 1981 Jul; 1(7):573-83.
Score: 0.000
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Kozak CA, Fournier RE, Leinwand LA, Ruddle FH. Assignment of the gene governing cellular ouabain resistance to Mus musculus chromosome 3 using human/mouse microcell hybrids. Biochem Genet. 1979 Feb; 17(1-2):23-34.
Score: 0.000
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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