 Connection
David Fox to Animals
This is a "connection" page, showing publications David Fox has written about Animals.
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Connection Strength |
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0.681 |
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McDougle DR, Moon JJ, Fox DA. Myeloid-Derived Suppressor Cells in Inflammatory Arthritis. Int J Mol Sci. 2026 Jun 14; 27(12).
Score: 0.050
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Gurrea-Rubio M, Lin F, Wicha MS, Mao-Draayer Y, Fox DA. Ligands of CD6: roles in the pathogenesis and treatment of cancer. Front Immunol. 2024; 15:1528478.
Score: 0.045
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Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells. Cancer Immunol Immunother. 2024 Jan 27; 73(2):34.
Score: 0.042
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Ruth JH, Gurrea-Rubio M, Athukorala KS, Rasmussen SM, Weber DP, Randon PM, Gedert RJ, Lind ME, Amin MA, Campbell PL, Tsou PS, Mao-Draayer Y, Wu Q, Lanigan TM, Keshamouni VG, Singer NG, Lin F, Fox DA. CD6 is a target for cancer immunotherapy. JCI Insight. 2021 03 08; 6(5).
Score: 0.035
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Fox DA. Current and future approaches to the treatment of immunologic diseases: new targets and new therapeutic agents. Transl Res. 2015 Feb; 165(2):251-4.
Score: 0.022
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Cooney LA, Fox DA. Regulation of Th17 maturation by interleukin 4. Crit Rev Immunol. 2013; 33(5):379-87.
Score: 0.020
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Cooney LA, Towery K, Endres J, Fox DA. Sensitivity and resistance to regulation by IL-4 during Th17 maturation. J Immunol. 2011 Nov 01; 187(9):4440-50.
Score: 0.018
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Kato H, Fox DA. Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis? Clin Transl Sci. 2010 Dec; 3(6):319-26.
Score: 0.017
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Fox DA, Gizinski A, Morgan R, Lundy SK. Cell-cell interactions in rheumatoid arthritis synovium. Rheum Dis Clin North Am. 2010 May; 36(2):311-23.
Score: 0.016
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Lundy SK, Fox DA. Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis. Arthritis Res Ther. 2009; 11(4):R128.
Score: 0.016
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Tesmer LA, Lundy SK, Sarkar S, Fox DA. Th17 cells in human disease. Immunol Rev. 2008 Jun; 223:87-113.
Score: 0.014
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Tran CN, Davis MJ, Tesmer LA, Endres JL, Motyl CD, Smuda C, Somers EC, Chung KC, Urquhart AG, Lundy SK, Kovats S, Fox DA. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 2007 May; 56(5):1497-506.
Score: 0.013
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Sarkar S, Tesmer LA, Hindnavis V, Endres JL, Fox DA. Interleukin-17 as a molecular target in immune-mediated arthritis: immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4. Arthritis Rheum. 2007 Jan; 56(1):89-100.
Score: 0.013
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Lundy SK, Sarkar S, Tesmer LA, Fox DA. Cells of the synovium in rheumatoid arthritis. T lymphocytes. Arthritis Res Ther. 2007; 9(1):202.
Score: 0.013
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Shaikh FS, Shanta MA, Singh AK, Daniels AM, Khuder SA, Thiele GM, Reed GW, Kremer JM, Pappas DA, Curtis JR, O'Dell JR, Ouseph MM, Fox DA, Ahmed S. TWEAK receptor (Fn14) exacerbates TNF-a-induced inflammation in rheumatoid arthritis synovial fibroblasts and influences response to anti-TNF-a therapy. Cell Mol Immunol. 2026 Mar; 23(3):315-328.
Score: 0.012
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Gurrea-Rubio M, Fox DA, Castresana JS. CD6 in Human Disease. Cells. 2025 02 13; 14(4).
Score: 0.011
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Sarkar S, Fox DA. Dendritic cells in rheumatoid arthritis. Front Biosci. 2005 Jan 01; 10:656-65.
Score: 0.011
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Muraoka S, Brodie WD, Mattichak MN, Gurrea-Rubio M, Ikari Y, Foster C, Amin MA, Khanna N, Amin H, Campbell PL, Vichaikul S, Model EN, Omara MM, Petrovski S, Kozicki K, Amarista C, Webber A, Ali M, Palisoc PJ, Hervoso J, Ruth JH, Tsoi LC, Varga J, Gudjonsson JE, Khanna D, Fox DA, Tsou PS. Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis. Arthritis Rheumatol. 2025 Jan; 77(1):80-91.
Score: 0.011
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Gurrea-Rubio M, Wang Q, Mills EA, Wu Q, Pitt D, Tsou PS, Fox DA, Mao-Draayer Y. Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NF?B and Mitochondrial Pathways. Int J Mol Sci. 2024 Feb 20; 25(5).
Score: 0.011
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Zhang L, Luo L, Chen JY, Singh R, Baldwin WM, Fox DA, Lindner DJ, Martin DF, Caspi RR, Lin F. A CD6-targeted antibody-drug conjugate as a potential therapy for T cell-mediated disorders. JCI Insight. 2023 12 08; 8(23).
Score: 0.010
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Lu C, Cheng RJ, Zhang Q, Hu Y, Pu Y, Wen J, Zhong Y, Tang Z, Wu L, Wei S, Tsou PS, Fox DA, Li S, Luo Y, Liu Y. Herbal compound cepharanthine attenuates inflammatory arthritis by blocking macrophage M1 polarization. Int Immunopharmacol. 2023 Dec; 125(Pt B):111175.
Score: 0.010
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Parameswaran N, Luo L, Zhang L, Chen J, DiFilippo FP, Androjna C, Fox DA, Ondrejka SL, Hsi ED, Jagadeesh D, Lindner DJ, Lin F. CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma. Leukemia. 2023 10; 37(10):2050-2057.
Score: 0.010
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Zhang L, Borjini N, Lun Y, Parab S, Asonye G, Singh R, Bell BA, Bonilha VL, Ivanov A, Fox DA, Caspi RR, Lin F. CDCP1 regulates retinal pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis. JCI Insight. 2022 09 22; 7(18).
Score: 0.010
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Siegel RJ, Singh AK, Panipinto PM, Shaikh FS, Vinh J, Han SU, Kenney HM, Schwarz EM, Crowson CS, Khuder SA, Khuder BS, Fox DA, Ahmed S. Extracellular sulfatase-2 is overexpressed in rheumatoid arthritis and mediates the TNF-a-induced inflammatory activation of synovial fibroblasts. Cell Mol Immunol. 2022 10; 19(10):1185-1195.
Score: 0.010
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Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1. J Clin Invest. 2022 06 01; 132(11).
Score: 0.009
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Hoy MJ, Park E, Lee H, Lim WY, Cole DC, DeBouver ND, Bobay BG, Pierce PG, Fox D, Ciofani M, Juvvadi PR, Steinbach W, Hong J, Heitman J. Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus. mBio. 2022 06 28; 13(3):e0104922.
Score: 0.009
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Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, Tsou PS. Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma. JCI Insight. 2022 05 09; 7(9).
Score: 0.009
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O'Neil LJ, Barrera-Vargas A, Sandoval-Heglund D, Merayo-Chalico J, Aguirre-Aguilar E, Aponte AM, Ruiz-Perdomo Y, Gucek M, El-Gabalawy H, Fox DA, Katz JD, Kaplan MJ, Carmona-Rivera C. Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis. Sci Adv. 2020 10; 6(44).
Score: 0.008
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Li Y, Ruth JH, Rasmussen SM, Athukorala KS, Weber DP, Amin MA, Campbell PL, Singer NG, Fox DA, Lin F. Attenuation of Murine Collagen-Induced Arthritis by Targeting CD6. Arthritis Rheumatol. 2020 09; 72(9):1505-1513.
Score: 0.008
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Carmona-Rivera C, Carlucci PM, Goel RR, James E, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ. Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis. JCI Insight. 2020 07 09; 5(13).
Score: 0.008
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Ianiri G, Coelho MA, Ruchti F, Sparber F, McMahon TJ, Fu C, Bolejack M, Donovan O, Smutney H, Myler P, Dietrich F, Fox D, LeibundGut-Landmann S, Heitman J. HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15884-15894.
Score: 0.008
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Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Amin MA, Zomorrodi RK, Arami S, Gonzalez M, Rao V, Zanotti B, Fox DA, Sweiss N, Shahrara S. IRAK4 inhibition: a promising strategy for treating RA joint inflammation and bone erosion. Cell Mol Immunol. 2021 09; 18(9):2199-2210.
Score: 0.008
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Scarneo SA, Eibschutz LS, Bendele PJ, Yang KW, Totzke J, Hughes P, Fox DA, Haystead TAJ. Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice. Arthritis Res Ther. 2019 12 17; 21(1):292.
Score: 0.008
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Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, Lee SC, Chen YL, Mutz M, Spicer LD, Schumacher MA, Heitman J, Steinbach WJ. Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun. 2019 09 19; 10(1):4275.
Score: 0.008
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Zhang L, Dai Y, Huang P, Saunders TL, Fox DA, Xu J, Lin F. Absence of complement component 3 does not prevent classical pathway-mediated hemolysis. Blood Adv. 2019 06 25; 3(12):1808-1814.
Score: 0.008
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Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S. Macrophages are the primary effector cells in IL-7-induced arthritis. Cell Mol Immunol. 2020 07; 17(7):728-740.
Score: 0.008
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Du Y, Lu C, Morgan RL, Stinson WA, Campbell PL, Cealey E, Fu W, Lepore NJ, Hervoso JL, Cui H, Urquhart AG, Lawton JN, Chung KC, Fox DA, Amin MA. Angiogenic and Arthritogenic Properties of the Soluble Form of CD13. J Immunol. 2019 07 15; 203(2):360-369.
Score: 0.008
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Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF. Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. J Med Chem. 2019 05 23; 62(10):4884-4901.
Score: 0.008
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Kahl DJ, Hutchings KM, Lisabeth EM, Haak AJ, Leipprandt JR, Dexheimer T, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD. 5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. J Med Chem. 2019 05 09; 62(9):4350-4369.
Score: 0.008
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Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH. Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3695-3702.
Score: 0.008
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Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology. 2018 10; 43(11):2299-2309.
Score: 0.007
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Xu J, Zhang L, Xie M, Li Y, Huang P, Saunders TL, Fox DA, Rosenquist R, Lin F. Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy. J Immunol. 2018 06 15; 200(12):4094-4101.
Score: 0.007
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Consuegra-Fernández M, Lin F, Fox DA, Lozano F. Clinical and experimental evidence for targeting CD6 in immune-based disorders. Autoimmun Rev. 2018 May; 17(5):493-503.
Score: 0.007
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Zhang L, Li Y, Qiu W, Bell BA, Dvorina N, Baldwin WM, Singer N, Kern T, Caspi RR, Fox DA, Lin F. Targeting CD6 for the treatment of experimental autoimmune uveitis. J Autoimmun. 2018 06; 90:84-93.
Score: 0.007
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O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA. A unique role for galectin-9 in angiogenesis and inflammatory arthritis. Arthritis Res Ther. 2018 02 12; 20(1):31.
Score: 0.007
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Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F. CD318 is a ligand for CD6. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):E6912-E6921.
Score: 0.007
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Asif Amin M, Fox DA, Ruth JH. Synovial cellular and molecular markers in rheumatoid arthritis. Semin Immunopathol. 2017 06; 39(4):385-393.
Score: 0.007
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Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorg Med Chem Lett. 2017 04 15; 27(8):1744-1749.
Score: 0.007
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Li Y, Singer NG, Whitbred J, Bowen MA, Fox DA, Lin F. CD6 as a potential target for treating multiple sclerosis. Proc Natl Acad Sci U S A. 2017 03 07; 114(10):2687-2692.
Score: 0.007
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Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM. DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. Nat Commun. 2017 02 06; 8:14252.
Score: 0.007
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Edhayan G, Ohara RA, Stinson WA, Amin MA, Isozaki T, Ha CM, Haines GK, Morgan R, Campbell PL, Arbab AS, Friday SC, Fox DA, Ruth JH. Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis. Arthritis Res Ther. 2016 Apr 12; 18:87.
Score: 0.006
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Fox DA. Biological therapies: a novel approach to the treatment of autoimmune disease. Am J Med. 1995 Jul; 99(1):82-8.
Score: 0.006
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Mukai T, Gallant R, Ishida S, Kittaka M, Yoshitaka T, Fox DA, Morita Y, Nishida K, Rottapel R, Ueki Y. Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice. Arthritis Rheumatol. 2015 Mar; 67(3):656-67.
Score: 0.006
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Mukai T, Gallant R, Ishida S, Yoshitaka T, Kittaka M, Nishida K, Fox DA, Morita Y, Ueki Y. SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model. PLoS One. 2014; 9(8):e105518.
Score: 0.006
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Haak AJ, Tsou PS, Amin MA, Ruth JH, Campbell P, Fox DA, Khanna D, Larsen SD, Neubig RR. Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury. J Pharmacol Exp Ther. 2014 Jun; 349(3):480-6.
Score: 0.005
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Klinker MW, Reed TJ, Fox DA, Lundy SK. Interleukin-5 supports the expansion of fas ligand-expressing killer B cells that induce antigen-specific apoptosis of CD4(+) T cells and secrete interleukin-10. PLoS One. 2013; 8(8):e70131.
Score: 0.005
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Ling S, Cline EN, Haug TS, Fox DA, Holoshitz J. Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Rheum. 2013 Mar; 65(3):618-26.
Score: 0.005
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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