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Connection

David Fox to Humans

This is a "connection" page, showing publications David Fox has written about Humans.

 
Connection Strength
  
 
 
0.739
  
  1. McDougle DR, Moon JJ, Fox DA. Myeloid-Derived Suppressor Cells in Inflammatory Arthritis. Int J Mol Sci. 2026 Jun 14; 27(12).
    View in: PubMed
    Score: 0.024
  2. Tsou PS, Ali RA, Lu C, Sule G, Carmona-Rivera C, Lucotti S, Ikari Y, Wu Q, Campbell PL, Gurrea-Rubio M, Maeda K, Fox SE, Brodie WD, Mattichak MN, Foster C, Tambralli A, Yalavarthi S, Amin MA, Kmetova K, Fonseca BM, Chong E, Zuo Y, Maile MD, Imberti L, Caruso A, Caccuri F, Quaresima V, Sottini A, Kuhns DB, Fink D, Castagnoli R, Delmonte OM, Kenney H, Zhang Y, Magliocco M, Su H, Notarangelo L, Zemans RL, Mao-Draayer Y, Matei IR, Salvatore M, Lyden D, Kanthi Y, Kaplan MJ, Knight JS, Fox DA. Soluble CD13 is a potential mediator of neutrophil-induced thrombogenic inflammation in SARS-CoV-2 infection. JCI Insight. 2025 05 08; 10(9).
    View in: PubMed
    Score: 0.022
  3. Gurrea-Rubio M, Lin F, Wicha MS, Mao-Draayer Y, Fox DA. Ligands of CD6: roles in the pathogenesis and treatment of cancer. Front Immunol. 2024; 15:1528478.
    View in: PubMed
    Score: 0.022
  4. Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells. Cancer Immunol Immunother. 2024 Jan 27; 73(2):34.
    View in: PubMed
    Score: 0.020
  5. Wallace BI, Cooney L, Fox DA. New molecular targets in the treatment of rheumatoid arthritis. Curr Opin Rheumatol. 2024 05 01; 36(3):235-240.
    View in: PubMed
    Score: 0.020
  6. Ruth JH, Gurrea-Rubio M, Athukorala KS, Rasmussen SM, Weber DP, Randon PM, Gedert RJ, Lind ME, Amin MA, Campbell PL, Tsou PS, Mao-Draayer Y, Wu Q, Lanigan TM, Keshamouni VG, Singer NG, Lin F, Fox DA. CD6 is a target for cancer immunotherapy. JCI Insight. 2021 03 08; 6(5).
    View in: PubMed
    Score: 0.017
  7. Fox DA, Lundy SK, Whitfield ML, Berrocal V, Campbell P, Rasmussen S, Ohara R, Stinson A, Gurrea-Rubio M, Wiewiora E, Spino C, Bush E, Furst D, Pillai S, Khanna D. Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis. Arthritis Res Ther. 2021 01 06; 23(1):10.
    View in: PubMed
    Score: 0.016
  8. Lu C, Amin MA, Fox DA. CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders. J Immunol. 2020 01 01; 204(1):3-11.
    View in: PubMed
    Score: 0.015
  9. Fox DA. The role of CD6 in autoimmune diseases. Cell Mol Immunol. 2018 11; 15(11):1001-1002.
    View in: PubMed
    Score: 0.014
  10. Fox D, Campagna EJ, Finnell SM, Partrick DA, Kempe A. Concomitant Fundoplication With Gastrostomy: A Two-State Comparison Showing Continued Use of Reflux Medications. J Pediatr Gastroenterol Nutr. 2016 12; 63(6):e163-e168.
    View in: PubMed
    Score: 0.012
  11. Tsou PS, Amin MA, Campbell PL, Zakhem G, Balogh B, Edhayan G, Ohara RA, Schiopu E, Khanna D, Koch AE, Fox DA. Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma. J Invest Dermatol. 2015 Dec; 135(12):3153-3162.
    View in: PubMed
    Score: 0.011
  12. Fox DA. Citrullination: A Specific Target for the Autoimmune Response in Rheumatoid Arthritis. J Immunol. 2015 Jul 01; 195(1):5-7.
    View in: PubMed
    Score: 0.011
  13. Morgan R, Endres J, Behbahani-Nejad N, Phillips K, Ruth JH, Friday SC, Edhayan G, Lanigan T, Urquhart A, Chung KC, Fox DA. Expression and function of aminopeptidase N/CD13 produced by fibroblast-like synoviocytes in rheumatoid arthritis: role of CD13 in chemotaxis of cytokine-activated T cells independent of enzymatic activity. Arthritis Rheumatol. 2015 Jan; 67(1):74-85.
    View in: PubMed
    Score: 0.011
  14. Fox D, Campagna EJ, Friedlander J, Partrick DA, Rees DI, Kempe A. National trends and outcomes of pediatric gastrostomy tube placement. J Pediatr Gastroenterol Nutr. 2014 Nov; 59(5):582-8.
    View in: PubMed
    Score: 0.011
  15. Fox DA. Current and future approaches to the treatment of immunologic diseases: new targets and new therapeutic agents. Transl Res. 2015 Feb; 165(2):251-4.
    View in: PubMed
    Score: 0.011
  16. Fox D, Brittan M, Stille C. The Pediatric Inpatient Family Care Conference: a proposed structure toward shared decision-making. Hosp Pediatr. 2014 Sep; 4(5):305-10.
    View in: PubMed
    Score: 0.011
  17. Fox D, Friedlander JA. Pediatric endoscopic gastrostomy tubes: outcomes that guide decision making. J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):5-6.
    View in: PubMed
    Score: 0.010
  18. Gladue HS, Fox DA. Voriconazole-induced periostitis causing arthralgias mimicking a flare of granulomatosis with polyangiitis. J Clin Rheumatol. 2013 Dec; 19(8):444-5.
    View in: PubMed
    Score: 0.010
  19. Kato H, Endres J, Fox DA. The roles of IFN-? versus IL-17 in pathogenic effects of human Th17 cells on synovial fibroblasts. Mod Rheumatol. 2013 Nov; 23(6):1140-50.
    View in: PubMed
    Score: 0.009
  20. Cooney LA, Fox DA. Regulation of Th17 maturation by interleukin 4. Crit Rev Immunol. 2013; 33(5):379-87.
    View in: PubMed
    Score: 0.009
  21. Fox D, Barnard J, Campagna EJ, Dickinson LM, Bruny J, Kempe A. Fundoplication and the pediatric surgeon: implications for shared decision-making and the medical home. Acad Pediatr. 2012 Nov-Dec; 12(6):558-66.
    View in: PubMed
    Score: 0.009
  22. Panush RS, Quismorio FP, Fox DA. Epilogue: how will we care for patients with early arthritis? Rheum Dis Clin North Am. 2012 May; 38(2):427-9.
    View in: PubMed
    Score: 0.009
  23. Seltz LB, Zimmer L, Ochoa-Nunez L, Rustici M, Bryant L, Fox D. Latino families' experiences with family-centered rounds at an academic children's hospital. Acad Pediatr. 2011 Sep-Oct; 11(5):432-8.
    View in: PubMed
    Score: 0.009
  24. Wallis SK, Cooney LA, Endres JL, Lee MJ, Ryu J, Somers EC, Fox DA. A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis. Arthritis Res Ther. 2011 Feb 04; 13(1):R15.
    View in: PubMed
    Score: 0.008
  25. Kahlenberg JM, Fox DA. Advances in the medical treatment of rheumatoid arthritis. Hand Clin. 2011 Feb; 27(1):11-20.
    View in: PubMed
    Score: 0.008
  26. Kato H, Fox DA. Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis? Clin Transl Sci. 2010 Dec; 3(6):319-26.
    View in: PubMed
    Score: 0.008
  27. Fox DA. Preface: rheumatoid arthritis--halfway there. Rheum Dis Clin North Am. 2010 May; 36(2):xiii-xiv.
    View in: PubMed
    Score: 0.008
  28. Fox DA, Gizinski A, Morgan R, Lundy SK. Cell-cell interactions in rheumatoid arthritis synovium. Rheum Dis Clin North Am. 2010 May; 36(2):311-23.
    View in: PubMed
    Score: 0.008
  29. Chung KC, Burke FD, Wilgis EFS, Regan M, Kim HM, Fox DA. A prospective study comparing outcomes after reconstruction in rheumatoid arthritis patients with severe ulnar drift deformities. Plast Reconstr Surg. 2009 Jun; 123(6):1769-1777.
    View in: PubMed
    Score: 0.007
  30. Chung KC, Burns PB, Wilgis EF, Burke FD, Regan M, Kim HM, Fox DA. A multicenter clinical trial in rheumatoid arthritis comparing silicone metacarpophalangeal joint arthroplasty with medical treatment. J Hand Surg Am. 2009 May-Jun; 34(5):815-23.
    View in: PubMed
    Score: 0.007
  31. Fox DA. Unity in the field of rheumatology: the role of the ACR. Arthritis Rheum. 2009 Feb; 60(2):313-6.
    View in: PubMed
    Score: 0.007
  32. Tesmer LA, Lundy SK, Sarkar S, Fox DA. Th17 cells in human disease. Immunol Rev. 2008 Jun; 223:87-113.
    View in: PubMed
    Score: 0.007
  33. Tran CN, Thacker SG, Louie DM, Oliver J, White PT, Endres JL, Urquhart AG, Chung KC, Fox DA. Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3. J Immunol. 2008 Mar 01; 180(5):2989-98.
    View in: PubMed
    Score: 0.007
  34. Fox DA. The past and the future of Arthritis & Rheumatism: a view from the American College of Rheumatology. Arthritis Rheum. 2008 Feb; 58(2 Suppl):S7-S10.
    View in: PubMed
    Score: 0.007
  35. Tran CN, Lundy SK, White PT, Endres JL, Motyl CD, Gupta R, Wilke CM, Shelden EA, Chung KC, Urquhart AG, Fox DA. Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells. Am J Pathol. 2007 Nov; 171(5):1588-98.
    View in: PubMed
    Score: 0.007
  36. Tran CN, Davis MJ, Tesmer LA, Endres JL, Motyl CD, Smuda C, Somers EC, Chung KC, Urquhart AG, Lundy SK, Kovats S, Fox DA. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 2007 May; 56(5):1497-506.
    View in: PubMed
    Score: 0.006
  37. Lundy SK, Sarkar S, Tesmer LA, Fox DA. Cells of the synovium in rheumatoid arthritis. T lymphocytes. Arthritis Res Ther. 2007; 9(1):202.
    View in: PubMed
    Score: 0.006
  38. Deane KD, Striebich CC, Feser ML, O'Dell JR, James JA, Sparks JA, Davis JM, Graf J, McMahon MA, Solow EB, Forbess LJ, Tiliakos A, Schiopu E, Danila MI, Horowitz DL, Kay J, Strickland CD, Guthridge JM, Arriens C, Grossman JM, Kristen Demoruelle M, Bemis EA, Frazer-Abel A, Fleischer CL, Fox DA, Mikuls TR, Greenleaf M, York K, Walker S, Keyes-Elstein L, Byron M, Fedler J, Goldmuntz EA, Holers VM. A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis. Arthritis Rheumatol. 2026 Apr; 78(4):809-820.
    View in: PubMed
    Score: 0.006
  39. Shaikh FS, Shanta MA, Singh AK, Daniels AM, Khuder SA, Thiele GM, Reed GW, Kremer JM, Pappas DA, Curtis JR, O'Dell JR, Ouseph MM, Fox DA, Ahmed S. TWEAK receptor (Fn14) exacerbates TNF-a-induced inflammation in rheumatoid arthritis synovial fibroblasts and influences response to anti-TNF-a therapy. Cell Mol Immunol. 2026 Mar; 23(3):315-328.
    View in: PubMed
    Score: 0.006
  40. Ikari Y, Lu C, Rosek A, Cai A, Khanna N, St Clair J, Webber A, Foster C, Chen YC, Ali RA, Khanna D, Fox DA, Tsou PS. Soluble CD13 in systemic sclerosis: clinical observations and transcriptomic insights from peripheral blood. Arthritis Res Ther. 2026 Jan 10; 28(1):30.
    View in: PubMed
    Score: 0.006
  41. Li S, Liu Y, Zhang H, Xu S, Wen X, Tang Y, Zhang N, Fox DA, Chen Y, Pan Y, Lu C. Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease. EBioMedicine. 2026 Jan; 123:106074.
    View in: PubMed
    Score: 0.006
  42. Stanley KT, VanDort C, Motyl C, Endres J, Fox DA. Immunocompetent properties of human osteoblasts: interactions with T lymphocytes. J Bone Miner Res. 2006 Jan; 21(1):29-36.
    View in: PubMed
    Score: 0.006
  43. van Dooren HJ, van Schaik M, Dorjée AL, Arends EJ, Mackay M, Cooney L, Fox DA, Wofsy D, Smilek D, Aranow C, Dall'Era M, Huizinga TWJ, van Kooten C, Toes REM, Diamond B, Teng YKO, Suurmond J. Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell-Targeting Treatment in Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2025 Nov; 77(11):1560-1572.
    View in: PubMed
    Score: 0.006
  44. Gurrea-Rubio M, Fox DA, Castresana JS. CD6 in Human Disease. Cells. 2025 02 13; 14(4).
    View in: PubMed
    Score: 0.005
  45. Sarkar S, Fox DA. Dendritic cells in rheumatoid arthritis. Front Biosci. 2005 Jan 01; 10:656-65.
    View in: PubMed
    Score: 0.005
  46. Muraoka S, Brodie WD, Mattichak MN, Gurrea-Rubio M, Ikari Y, Foster C, Amin MA, Khanna N, Amin H, Campbell PL, Vichaikul S, Model EN, Omara MM, Petrovski S, Kozicki K, Amarista C, Webber A, Ali M, Palisoc PJ, Hervoso J, Ruth JH, Tsoi LC, Varga J, Gudjonsson JE, Khanna D, Fox DA, Tsou PS. Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis. Arthritis Rheumatol. 2025 Jan; 77(1):80-91.
    View in: PubMed
    Score: 0.005
  47. Tebo AE, Willis R, Nwosu A, Bashleben C, Fox DA, Linden MA, Karlon WJ. Reporting and Establishment of Reference Intervals for Antiphospholipid Antibody Immunoassays: A Survey of Participants in the College of American Pathologists Proficiency Testing Program. Arch Pathol Lab Med. 2024 06 01; 148(6):686-693.
    View in: PubMed
    Score: 0.005
  48. Gurrea-Rubio M, Wang Q, Mills EA, Wu Q, Pitt D, Tsou PS, Fox DA, Mao-Draayer Y. Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NF?B and Mitochondrial Pathways. Int J Mol Sci. 2024 Feb 20; 25(5).
    View in: PubMed
    Score: 0.005
  49. Shaikh FS, Siegel RJ, Srivastava A, Fox DA, Ahmed S. Challenges and promise of targeting miRNA in rheumatic diseases: a computational approach to identify miRNA association with cell types, cytokines, and disease mechanisms. Front Immunol. 2023; 14:1322806.
    View in: PubMed
    Score: 0.005
  50. Zhang L, Luo L, Chen JY, Singh R, Baldwin WM, Fox DA, Lindner DJ, Martin DF, Caspi RR, Lin F. A CD6-targeted antibody-drug conjugate as a potential therapy for T cell-mediated disorders. JCI Insight. 2023 12 08; 8(23).
    View in: PubMed
    Score: 0.005
  51. Xiao Q, Mears J, Nathan A, Ishigaki K, Baglaenko Y, Lim N, Cooney LA, Harris KM, Anderson MS, Fox DA, Smilek DE, Krueger JG, Raychaudhuri S. Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin. Nat Commun. 2023 10 07; 14(1):6268.
    View in: PubMed
    Score: 0.005
  52. Lu C, Li S, Qing P, Zhang Q, Ji X, Tang Z, Chen C, Wu T, Hu Y, Zhao Y, Zhang X, He Q, Fox DA, Tan C, Luo Y, Liu Y. Single-cell transcriptome analysis and protein profiling reveal broad immune system activation in IgG4-related disease. JCI Insight. 2023 09 08; 8(17).
    View in: PubMed
    Score: 0.005
  53. Parameswaran N, Luo L, Zhang L, Chen J, DiFilippo FP, Androjna C, Fox DA, Ondrejka SL, Hsi ED, Jagadeesh D, Lindner DJ, Lin F. CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma. Leukemia. 2023 10; 37(10):2050-2057.
    View in: PubMed
    Score: 0.005
  54. Xie MM, Dai B, Hackney JA, Sun T, Zhang J, Jackman JK, Jeet S, Irizarry-Caro RA, Fu Y, Liang Y, Bender H, Shamir ER, Keir ME, Bevers J, Nakamura G, Townsend MJ, Fox DA, Scherl A, Lee WP, Martin F, Godowski PJ, Pappu R, Yi T. An agonistic anti-signal regulatory protein a antibody for chronic inflammatory diseases. Cell Rep Med. 2023 08 15; 4(8):101130.
    View in: PubMed
    Score: 0.005
  55. Wu Q, Thakolwiboon S, Ali AS, Wang Q, Dwyer D, Fox DA, Mao-Draayer Y. MOG-specific T cell response amplified in para- and post-SAR-CoV-2 infection in myelin oligodendrocyte glycoprotein antibody-associated disease. J Neuroimmunol. 2023 09 15; 382:578143.
    View in: PubMed
    Score: 0.005
  56. Mehta BK, Espinoza ME, Franks JM, Yuan Y, Wang Y, Wood T, Gudjonsson JE, Spino C, Fox DA, Khanna D, Whitfield ML. Machine-learning classification identifies patients with early systemic sclerosis as abatacept responders via CD28 pathway modulation. JCI Insight. 2022 12 22; 7(24).
    View in: PubMed
    Score: 0.005
  57. Zhang L, Borjini N, Lun Y, Parab S, Asonye G, Singh R, Bell BA, Bonilha VL, Ivanov A, Fox DA, Caspi RR, Lin F. CDCP1 regulates retinal pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis. JCI Insight. 2022 09 22; 7(18).
    View in: PubMed
    Score: 0.005
  58. Khanna D, Padilla C, Tsoi LC, Nagaraja V, Khanna PP, Tabib T, Kahlenberg JM, Young A, Huang S, Gudjonsson JE, Fox DA, Lafyatis R. Tofacitinib blocks IFN-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial. JCI Insight. 2022 09 08; 7(17).
    View in: PubMed
    Score: 0.005
  59. Siegel RJ, Singh AK, Panipinto PM, Shaikh FS, Vinh J, Han SU, Kenney HM, Schwarz EM, Crowson CS, Khuder SA, Khuder BS, Fox DA, Ahmed S. Extracellular sulfatase-2 is overexpressed in rheumatoid arthritis and mediates the TNF-a-induced inflammatory activation of synovial fibroblasts. Cell Mol Immunol. 2022 10; 19(10):1185-1195.
    View in: PubMed
    Score: 0.005
  60. Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, Tsou PS. Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma. JCI Insight. 2022 05 09; 7(9).
    View in: PubMed
    Score: 0.005
  61. Ali A, Dwyer D, Wu Q, Wang Q, Dowling CA, Fox DA, Khanna D, Poland GA, Mao-Draayer Y. Characterization of humoral response to COVID mRNA vaccines in multiple sclerosis patients on disease modifying therapies. Vaccine. 2021 10 01; 39(41):6111-6116.
    View in: PubMed
    Score: 0.004
  62. Fox DA, He X, Abe A, Hollander T, Li LL, Kan L, Friedman AW, Shimizu Y, Shayman JA, Kozarsky K. The T lymphocyte structure CD60 contains a sialylated carbohydrate epitope that is expressed on both gangliosides and glycoproteins. Immunol Invest. 2001 May; 30(2):67-85.
    View in: PubMed
    Score: 0.004
  63. Yamamura Y, Gupta R, Morita Y, He X, Pai R, Endres J, Freiberg A, Chung K, Fox DA. Effector function of resting T cells: activation of synovial fibroblasts. J Immunol. 2001 Feb 15; 166(4):2270-5.
    View in: PubMed
    Score: 0.004
  64. Haque M, Siegel RJ, Fox DA, Ahmed S. Interferon-stimulated GTPases in autoimmune and inflammatory diseases: promising role for the guanylate-binding protein (GBP) family. Rheumatology (Oxford). 2021 02 01; 60(2):494-506.
    View in: PubMed
    Score: 0.004
  65. O'Neil LJ, Barrera-Vargas A, Sandoval-Heglund D, Merayo-Chalico J, Aguirre-Aguilar E, Aponte AM, Ruiz-Perdomo Y, Gucek M, El-Gabalawy H, Fox DA, Katz JD, Kaplan MJ, Carmona-Rivera C. Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis. Sci Adv. 2020 10; 6(44).
    View in: PubMed
    Score: 0.004
  66. Carmona-Rivera C, Carlucci PM, Goel RR, James E, Brooks SR, Rims C, Hoffmann V, Fox DA, Buckner JH, Kaplan MJ. Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis. JCI Insight. 2020 07 09; 5(13).
    View in: PubMed
    Score: 0.004
  67. Ianiri G, Coelho MA, Ruchti F, Sparber F, McMahon TJ, Fu C, Bolejack M, Donovan O, Smutney H, Myler P, Dietrich F, Fox D, LeibundGut-Landmann S, Heitman J. HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15884-15894.
    View in: PubMed
    Score: 0.004
  68. Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Amin MA, Zomorrodi RK, Arami S, Gonzalez M, Rao V, Zanotti B, Fox DA, Sweiss N, Shahrara S. IRAK4 inhibition: a promising strategy for treating RA joint inflammation and bone erosion. Cell Mol Immunol. 2021 09; 18(9):2199-2210.
    View in: PubMed
    Score: 0.004
  69. Wu Q, Mills EA, Wang Q, Dowling CA, Fisher C, Kirch B, Lundy SK, Fox DA, Mao-Draayer Y. Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis. JCI Insight. 2020 02 13; 5(3).
    View in: PubMed
    Score: 0.004
  70. Craft JE, Crow MK, Lockshin MD, Salmon JE, Diamond B, Elkon KB, Flood J, Fox DA, Gabriel SE, Gilkeson GS, Hahn BH, Hardin J, Koopman WJ, Seaman WE, Wofsy D, Sergent JS, Uknis AB, Weinblatt ME. Georgia Abortion Law and Our Commitment to Patients. Arthritis Rheumatol. 2020 02; 72(2):377-378.
    View in: PubMed
    Score: 0.004
  71. Scarneo SA, Eibschutz LS, Bendele PJ, Yang KW, Totzke J, Hughes P, Fox DA, Haystead TAJ. Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice. Arthritis Res Ther. 2019 12 17; 21(1):292.
    View in: PubMed
    Score: 0.004
  72. Khanna D, Spino C, Johnson S, Chung L, Whitfield ML, Denton CP, Berrocal V, Franks J, Mehta B, Molitor J, Steen VD, Lafyatis R, Simms RW, Gill A, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Schiopu E, Young A, Sandorfi N, Park J, Hant FN, Bernstein EJ, Chatterjee S, Castelino FV, Ajam A, Wang Y, Wood T, Allanore Y, Matucci-Cerinic M, Distler O, Singer O, Bush E, Fox DA, Furst DE. Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial. Arthritis Rheumatol. 2020 01; 72(1):125-136.
    View in: PubMed
    Score: 0.004
  73. Wallace BI, Lin P, Kamdar N, Noureldin M, Hayward R, Fox DA, Curtis JR, Saag KG, Waljee AK. Patterns of glucocorticoid prescribing and provider-level variation in a commercially insured incident rheumatoid arthritis population: A retrospective cohort study. Semin Arthritis Rheum. 2020 04; 50(2):228-236.
    View in: PubMed
    Score: 0.004
  74. Zhang L, Dai Y, Huang P, Saunders TL, Fox DA, Xu J, Lin F. Absence of complement component 3 does not prevent classical pathway-mediated hemolysis. Blood Adv. 2019 06 25; 3(12):1808-1814.
    View in: PubMed
    Score: 0.004
  75. Ohara RA, Edhayan G, Rasmussen SM, Isozaki T, Remmer HA, Lanigan TM, Campbell PL, Urquhart AG, Lawton JN, Chung KC, Fox DA, Ruth JH. Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis. Arthritis Rheumatol. 2019 08; 71(8):1241-1251.
    View in: PubMed
    Score: 0.004
  76. Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S. Macrophages are the primary effector cells in IL-7-induced arthritis. Cell Mol Immunol. 2020 07; 17(7):728-740.
    View in: PubMed
    Score: 0.004
  77. Du Y, Lu C, Morgan RL, Stinson WA, Campbell PL, Cealey E, Fu W, Lepore NJ, Hervoso JL, Cui H, Urquhart AG, Lawton JN, Chung KC, Fox DA, Amin MA. Angiogenic and Arthritogenic Properties of the Soluble Form of CD13. J Immunol. 2019 07 15; 203(2):360-369.
    View in: PubMed
    Score: 0.004
  78. Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF. Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. J Med Chem. 2019 05 23; 62(10):4884-4901.
    View in: PubMed
    Score: 0.004
  79. Kirsch AH, Mahmood AA, Endres J, Bohra L, Bonish B, Weber K, Fox DA. Apoptosis of human T-cells: induction by glucocorticoids or surface receptor ligation in vitro and ex vivo. J Biol Regul Homeost Agents. 1999 Apr-Jun; 13(2):80-9.
    View in: PubMed
    Score: 0.004
  80. Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH. Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3695-3702.
    View in: PubMed
    Score: 0.004
  81. Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology. 2018 10; 43(11):2299-2309.
    View in: PubMed
    Score: 0.003
  82. Mandelin AM, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR. Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis. Arthritis Rheumatol. 2018 06; 70(6):841-854.
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    Score: 0.003
  83. Consuegra-Fernández M, Lin F, Fox DA, Lozano F. Clinical and experimental evidence for targeting CD6 in immune-based disorders. Autoimmun Rev. 2018 May; 17(5):493-503.
    View in: PubMed
    Score: 0.003
  84. Zhang L, Li Y, Qiu W, Bell BA, Dvorina N, Baldwin WM, Singer N, Kern T, Caspi RR, Fox DA, Lin F. Targeting CD6 for the treatment of experimental autoimmune uveitis. J Autoimmun. 2018 06; 90:84-93.
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    Score: 0.003
  85. O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA. A unique role for galectin-9 in angiogenesis and inflammatory arthritis. Arthritis Res Ther. 2018 02 12; 20(1):31.
    View in: PubMed
    Score: 0.003
  86. Elshabrawy HA, Volin MV, Essani AB, Chen Z, McInnes IB, Van Raemdonck K, Palasiewicz K, Arami S, Gonzalez M, Ashour HM, Kim SJ, Zhou G, Fox DA, Shahrara S. IL-11 facilitates a novel connection between RA joint fibroblasts and endothelial cells. Angiogenesis. 2018 05; 21(2):215-228.
    View in: PubMed
    Score: 0.003
  87. Nagaraja V, Mara C, Khanna PP, Namas R, Young A, Fox DA, Laing T, McCune WJ, Dodge C, Rizzo D, Almackenzie M, Khanna D. Establishing clinical severity for PROMIS® measures in adult patients with rheumatic diseases. Qual Life Res. 2018 Mar; 27(3):755-764.
    View in: PubMed
    Score: 0.003
  88. Diaz LA, Friedman AW, He X, Kuick RD, Hanash SM, Fox DA. Monocyte-dependent regulation of T lymphocyte activation through CD98. Int Immunol. 1997 Sep; 9(9):1221-31.
    View in: PubMed
    Score: 0.003
  89. Totzke J, Gurbani D, Raphemot R, Hughes PF, Bodoor K, Carlson DA, Loiselle DR, Bera AK, Eibschutz LS, Perkins MM, Eubanks AL, Campbell PL, Fox DA, Westover KD, Haystead TAJ, Derbyshire ER. Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-a Inhibition for Cancer and Autoimmune Disease. Cell Chem Biol. 2017 Aug 17; 24(8):1029-1039.e7.
    View in: PubMed
    Score: 0.003
  90. Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F. CD318 is a ligand for CD6. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):E6912-E6921.
    View in: PubMed
    Score: 0.003
  91. Fechtner S, Fox DA, Ahmed S. Transforming growth factor ß activated kinase 1: a potential therapeutic target for rheumatic diseases. Rheumatology (Oxford). 2017 07 01; 56(7):1060-1068.
    View in: PubMed
    Score: 0.003
  92. Chung KC, Kotsis SV, Burns PB, Burke FD, Wilgis EFS, Fox DA, Kim HM. Seven-Year Outcomes of the Silicone Arthroplasty in Rheumatoid Arthritis Prospective Cohort Study. Arthritis Care Res (Hoboken). 2017 07; 69(7):973-981.
    View in: PubMed
    Score: 0.003
  93. Asif Amin M, Fox DA, Ruth JH. Synovial cellular and molecular markers in rheumatoid arthritis. Semin Immunopathol. 2017 06; 39(4):385-393.
    View in: PubMed
    Score: 0.003
  94. Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorg Med Chem Lett. 2017 04 15; 27(8):1744-1749.
    View in: PubMed
    Score: 0.003
  95. Li Y, Singer NG, Whitbred J, Bowen MA, Fox DA, Lin F. CD6 as a potential target for treating multiple sclerosis. Proc Natl Acad Sci U S A. 2017 03 07; 114(10):2687-2692.
    View in: PubMed
    Score: 0.003
  96. Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM. DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. Nat Commun. 2017 02 06; 8:14252.
    View in: PubMed
    Score: 0.003
  97. Fox DA. Rheumatoid Arthritis--heresies and speculations. Perspect Biol Med. 1997; 40(4):479-91.
    View in: PubMed
    Score: 0.003
  98. Elshabrawy HA, Essani AE, Szekanecz Z, Fox DA, Shahrara S. TLRs, future potential therapeutic targets for RA. Autoimmun Rev. 2017 Feb; 16(2):103-113.
    View in: PubMed
    Score: 0.003
  99. Tsou PS, Wren JD, Amin MA, Schiopu E, Fox DA, Khanna D, Sawalha AH. Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors. Arthritis Rheumatol. 2016 12; 68(12):2975-2985.
    View in: PubMed
    Score: 0.003
  100. Brittan M, Richardson T, Kenyon C, Sills MR, Fieldston E, Hall M, Fox D, Shah S, Berry J. Association between Postdischarge Oral Corticosteroid Prescription Fills and Readmission in Children with Asthma. J Pediatr. 2017 01; 180:163-169.e1.
    View in: PubMed
    Score: 0.003
  101. Singer NG, Richardson BC, Powers D, Hooper F, Lialios F, Endres J, Bott CM, Fox DA. Role of the CD6 glycoprotein in antigen-specific and autoreactive responses of cloned human T lymphocytes. Immunology. 1996 Aug; 88(4):537-43.
    View in: PubMed
    Score: 0.003
  102. Edhayan G, Ohara RA, Stinson WA, Amin MA, Isozaki T, Ha CM, Haines GK, Morgan R, Campbell PL, Arbab AS, Friday SC, Fox DA, Ruth JH. Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis. Arthritis Res Ther. 2016 Apr 12; 18:87.
    View in: PubMed
    Score: 0.003
  103. Fox DA. Biological therapies: a novel approach to the treatment of autoimmune disease. Am J Med. 1995 Jul; 99(1):82-8.
    View in: PubMed
    Score: 0.003
  104. Waljee J, Zhong L, Baser O, Yuce H, Fox DA, Chung KC. The incidence of upper and lower extremity surgery for rheumatoid arthritis among Medicare beneficiaries. J Bone Joint Surg Am. 2015 Mar 04; 97(5):403-10.
    View in: PubMed
    Score: 0.003
  105. Mukai T, Gallant R, Ishida S, Kittaka M, Yoshitaka T, Fox DA, Morita Y, Nishida K, Rottapel R, Ueki Y. Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice. Arthritis Rheumatol. 2015 Mar; 67(3):656-67.
    View in: PubMed
    Score: 0.003
  106. Brittan MS, Sills MR, Fox D, Campagna EJ, Shmueli D, Feinstein JA, Kempe A. Outpatient follow-up visits and readmission in medically complex children enrolled in Medicaid. J Pediatr. 2015 Apr; 166(4):998-1005.e1.
    View in: PubMed
    Score: 0.003
  107. Zhong L, Chung KC, Baser O, Fox DA, Yuce H, Waljee JF. Variation in rheumatoid hand and wrist surgery among medicare beneficiaries: a population-based cohort study. J Rheumatol. 2015 Mar; 42(3):429-36.
    View in: PubMed
    Score: 0.003
  108. Baugh L, Phan I, Begley DW, Clifton MC, Armour B, Dranow DM, Taylor BM, Muruthi MM, Abendroth J, Fairman JW, Fox D, Dieterich SH, Staker BL, Gardberg AS, Choi R, Hewitt SN, Napuli AJ, Myers J, Barrett LK, Zhang Y, Ferrell M, Mundt E, Thompkins K, Tran N, Lyons-Abbott S, Abramov A, Sekar A, Serbzhinskiy D, Lorimer D, Buchko GW, Stacy R, Stewart LJ, Edwards TE, Van Voorhis WC, Myler PJ. Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb). 2015 Mar; 95(2):142-8.
    View in: PubMed
    Score: 0.003
  109. Chung KC, Nellans KW, Burns PB, Wilgis EF, Burke FD, Fox DA, Kim HM. Patient expectations and long-term outcomes in rheumatoid arthritis patients: results from the SARA (Silicone Arthroplasty in Rheumatoid Arthritis) study. Clin Rheumatol. 2015 Apr; 34(4):641-51.
    View in: PubMed
    Score: 0.003
  110. Bott CM, Doshi JB, Li LL, McMurtry SA, Sanders JL, Fox DA. Transcriptional regulation of CD6 expression on human T lymphocytes by phorbol ester. J Immunol. 1994 Jul 01; 153(1):1-9.
    View in: PubMed
    Score: 0.003
  111. Haak AJ, Tsou PS, Amin MA, Ruth JH, Campbell P, Fox DA, Khanna D, Larsen SD, Neubig RR. Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury. J Pharmacol Exp Ther. 2014 Jun; 349(3):480-6.
    View in: PubMed
    Score: 0.003
  112. Freidman AW, Diaz LA, Moore S, Schaller J, Fox DA. The human 4F2 antigen: evidence for cryptic and noncryptic epitopes and for a role of 4F2 in human T lymphocyte activation. Cell Immunol. 1994 Apr 01; 154(1):253-63.
    View in: PubMed
    Score: 0.003
  113. Tsou PS, Balogh B, Pinney AJ, Zakhem G, Lozier A, Amin MA, Stinson WA, Schiopu E, Khanna D, Fox DA, Koch AE. Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts. Arthritis Res Ther. 2014; 16(5):411.
    View in: PubMed
    Score: 0.003
  114. Kitko CL, Levine JE, Storer BE, Chai X, Fox DA, Braun TM, Couriel DR, Martin PJ, Flowers ME, Hansen JA, Chang L, Conlon M, Fiema BJ, Morgan R, Pongtornpipat P, Lamiman K, Ferrara JL, Lee SJ, Paczesny S. Plasma CXCL9 elevations correlate with chronic GVHD diagnosis. Blood. 2014 Jan 30; 123(5):786-93.
    View in: PubMed
    Score: 0.003
  115. Cottier KE, Fogle EM, Fox DA, Ahmed S. Noxa in rheumatic diseases: present understanding and future impact. Rheumatology (Oxford). 2014 Sep; 53(9):1539-46.
    View in: PubMed
    Score: 0.003
  116. Chetta M, Burns PB, Kim HM, Burke FD, Wilgis EFS, Fox DA, Chung KC. The effect of swan neck and boutonniere deformities on the outcome of silicone metacarpophalangeal joint arthroplasty in rheumatoid arthritis. Plast Reconstr Surg. 2013 Sep; 132(3):597-603.
    View in: PubMed
    Score: 0.002
  117. Bott CM, Doshi JB, Morimoto C, Romain PL, Fox DA. Activation of human T cells through CD6: functional effects of a novel anti-CD6 monoclonal antibody and definition of four epitopes of the CD6 glycoprotein. Int Immunol. 1993 Jul; 5(7):783-92.
    View in: PubMed
    Score: 0.002
  118. Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med. 2013 Mar 27; 5(178):178ra40.
    View in: PubMed
    Score: 0.002
  119. Ling S, Cline EN, Haug TS, Fox DA, Holoshitz J. Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Rheum. 2013 Mar; 65(3):618-26.
    View in: PubMed
    Score: 0.002
  120. Chung KC, Burns PB, Reichert HA, Fox DA, Burke FD, Wilgis EF, Regan M, Kim HM. Properties of the International Classification for Functioning, Disability and Health in assessing hand outcomes in patients with rheumatoid arthritis. J Rehabil Med. 2011 Mar; 43(4):292-8.
    View in: PubMed
    Score: 0.002
  121. Entezami P, Fox DA, Clapham PJ, Chung KC. Historical perspective on the etiology of rheumatoid arthritis. Hand Clin. 2011 Feb; 27(1):1-10.
    View in: PubMed
    Score: 0.002
  122. Gizinski AM, Fox DA, Sarkar S. Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets. Best Pract Res Clin Rheumatol. 2010 Aug; 24(4):463-77.
    View in: PubMed
    Score: 0.002
  123. Chung KC, Kotsis SV, Fox DA, Regan M, Burke FD, Wilgis EF, Kim HM. Differences between the United States and the United Kingdom in the treatment of rheumatoid arthritis: analyses from a hand arthroplasty trial. Clin Rheumatol. 2010 Apr; 29(4):363-7.
    View in: PubMed
    Score: 0.002
  124. Chung KC, Kotsis SV, Wilgis EF, Fox DA, Regan M, Kim HM, Burke FD. Outcomes of silicone arthroplasty for rheumatoid metacarpophalangeal joints stratified by fingers. J Hand Surg Am. 2009 Nov; 34(9):1647-52.
    View in: PubMed
    Score: 0.002
  125. Alderman AK, Chung KC, Kim HM, Fox DA, Ubel PA. Effectiveness of rheumatoid hand surgery: contrasting perceptions of hand surgeons and rheumatologists. J Hand Surg Am. 2003 Jan; 28(1):3-11; discussion 12-3.
    View in: PubMed
    Score: 0.001
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