Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Boris Draznin to Proto-Oncogene Proteins p21(ras)

This is a "connection" page, showing publications Boris Draznin has written about Proto-Oncogene Proteins p21(ras).

 
Connection Strength
 
 
 
2.241
 
  1. Thureen P, Reece M, Rodden D, Barbour L, Chappell J, Leitner JW, Jones RO, Draznin B. Increased farnesylation of p21-Ras and neonatal macrosomia in women with gestational diabetes. J Pediatr. 2006 Dec; 149(6):871-3.
    View in: PubMed
    Score: 0.259
  2. Stephens E, Thureen PJ, Goalstone ML, Anderson MS, Leitner JW, Hay WW, Draznin B. Fetal hyperinsulinemia increases farnesylation of p21 Ras in fetal tissues. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E217-23.
    View in: PubMed
    Score: 0.179
  3. Klemm DJ, Leitner JW, Watson P, Nesterova A, Reusch JE, Goalstone ML, Draznin B. Insulin-induced adipocyte differentiation. Activation of CREB rescues adipogenesis from the arrest caused by inhibition of prenylation. J Biol Chem. 2001 Jul 27; 276(30):28430-5.
    View in: PubMed
    Score: 0.176
  4. Draznin B, Miles P, Kruszynska Y, Olefsky J, Friedman J, Golovchenko I, Stjernholm R, Wall K, Reitman M, Accili D, Cooksey R, McClain D, Goalstone M. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology. 2000 Apr; 141(4):1310-6.
    View in: PubMed
    Score: 0.163
  5. Goalstone ML, Wall K, Leitner JW, Kurowski T, Ruderman N, Pan SJ, Ivy JL, Moller DE, Draznin B. Increased amounts of farnesylated p21Ras in tissues of hyperinsulinaemic animals. Diabetologia. 1999 Mar; 42(3):310-6.
    View in: PubMed
    Score: 0.151
  6. Goalstone ML, Leitner JW, Wall K, Dolgonos L, Rother KI, Accili D, Draznin B. Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor. J Biol Chem. 1998 Sep 11; 273(37):23892-6.
    View in: PubMed
    Score: 0.146
  7. Goalstone M, Carel K, Leitner JW, Draznin B. Insulin stimulates the phosphorylation and activity of farnesyltransferase via the Ras-mitogen-activated protein kinase pathway. Endocrinology. 1997 Dec; 138(12):5119-24.
    View in: PubMed
    Score: 0.139
  8. Goalstone M, Leitner JW, Draznin B. GTP loading of farnesylated p21Ras by insulin at the plasma membrane. Biochem Biophys Res Commun. 1997 Oct 09; 239(1):42-5.
    View in: PubMed
    Score: 0.137
  9. Leitner JW, Kline T, Carel K, Goalstone M, Draznin B. Hyperinsulinemia potentiates activation of p21Ras by growth factors. Endocrinology. 1997 May; 138(5):2211-4.
    View in: PubMed
    Score: 0.133
  10. Goalstone ML, Draznin B. Effect of insulin on farnesyltransferase activity in 3T3-L1 adipocytes. J Biol Chem. 1996 Nov 01; 271(44):27585-9.
    View in: PubMed
    Score: 0.129
  11. DePaolo D, Reusch JE, Carel K, Bhuripanyo P, Leitner JW, Draznin B. Functional interactions of phosphatidylinositol 3-kinase with GTPase-activating protein in 3T3-L1 adipocytes. Mol Cell Biol. 1996 Apr; 16(4):1450-7.
    View in: PubMed
    Score: 0.123
  12. Reusch JE, Bhuripanyo P, Carel K, Leitner JW, Hsieh P, DePaolo D, Draznin B. Differential requirement for p21ras activation in the metabolic signaling by insulin. J Biol Chem. 1995 Feb 03; 270(5):2036-40.
    View in: PubMed
    Score: 0.114
  13. Draznin B, Chang L, Leitner JW, Takata Y, Olefsky JM. Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors. J Biol Chem. 1993 Sep 25; 268(27):19998-20001.
    View in: PubMed
    Score: 0.104
  14. Finlayson CA, Chappell J, Leitner JW, Goalstone ML, Garrity M, Nawaz S, Ciaraldi TP, Draznin B. Enhanced insulin signaling via Shc in human breast cancer. Metabolism. 2003 Dec; 52(12):1606-11.
    View in: PubMed
    Score: 0.052
  15. Goalstone ML, Natarajan R, Standley PR, Walsh MF, Leitner JW, Carel K, Scott S, Nadler J, Sowers JR, Draznin B. Insulin potentiates platelet-derived growth factor action in vascular smooth muscle cells. Endocrinology. 1998 Oct; 139(10):4067-72.
    View in: PubMed
    Score: 0.037
  16. Goalstone ML, Draznin B. Insulin signaling. West J Med. 1997 Sep; 167(3):166-73.
    View in: PubMed
    Score: 0.034
  17. Carel K, Kummer JL, Schubert C, Leitner W, Heidenreich KA, Draznin B. Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes. J Biol Chem. 1996 Nov 29; 271(48):30625-30.
    View in: PubMed
    Score: 0.032
  18. Schubert C, Carel K, DePaolo D, Leitner W, Draznin B. Interactions of protein kinase C with insulin signaling. Influence on GAP and Sos activities. J Biol Chem. 1996 Jun 28; 271(26):15311-4.
    View in: PubMed
    Score: 0.031
  19. Carel K, DePaolo D, Reusch JE, Leitner JW, Draznin B. Reduced phosphorylation of mitogen-activated protein kinase kinase in response to insulin in cells with truncated C-terminal domain of insulin receptor. Endocrinology. 1996 Jun; 137(6):2362-6.
    View in: PubMed
    Score: 0.031
  20. Langlois WJ, Medh J, Leitner JW, Sasaoka T, Olefsky JM, Draznin B. Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms. Endocrinology. 1994 Dec; 135(6):2412-7.
    View in: PubMed
    Score: 0.028
  21. Robinson LJ, Leitner W, Draznin B, Heidenreich KA. Evidence that p21ras mediates the neurotrophic effects of insulin and insulin-like growth factor I in chick forebrain neurons. Endocrinology. 1994 Dec; 135(6):2568-73.
    View in: PubMed
    Score: 0.028
  22. Sasaoka T, Langlois WJ, Bai F, Rose DW, Leitner JW, Decker SJ, Saltiel A, Gill GN, Kobayashi M, Draznin B, Olefsky JM. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites. J Biol Chem. 1996 Apr 05; 271(14):8338-44.
    View in: PubMed
    Score: 0.008
  23. Jhun BH, Haruta T, Meinkoth JL, Leitner W, Draznin B, Saltiel AR, Pang L, Sasaoka T, Olefsky JM. Signal transduction pathways leading to insulin-induced early gene induction. Biochemistry. 1995 Jun 27; 34(25):7996-8004.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)