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Connection

Boris Draznin to Insulin Receptor Substrate Proteins

This is a "connection" page, showing publications Boris Draznin has written about Insulin Receptor Substrate Proteins.

 
Connection Strength
 
 
 
0.882
 
  1. Adochio R, Leitner JW, Hedlund R, Draznin B. Rescuing 3T3-L1 adipocytes from insulin resistance induced by stimulation of Akt-mammalian target of rapamycin/p70 S6 kinase (S6K1) pathway and serine phosphorylation of insulin receptor substrate-1: effect of reduced expression of p85alpha subunit of phosphatidylinositol 3-kinase and S6K1 kinase. Endocrinology. 2009 Mar; 150(3):1165-73.
    View in: PubMed
    Score: 0.319
  2. Kim T, Wayne Leitner J, Adochio R, Draznin B. Knockdown of JNK rescues 3T3-L1 adipocytes from insulin resistance induced by mitochondrial dysfunction. Biochem Biophys Res Commun. 2009 Jan 23; 378(4):772-6.
    View in: PubMed
    Score: 0.080
  3. Draznin B. Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin. Diabetes. 2006 Aug; 55(8):2392-7.
    View in: PubMed
    Score: 0.068
  4. Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S, Leroith D, Kahn CR, Cantley LC, Friedman JE, Draznin B. Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess. J Biol Chem. 2005 Nov 11; 280(45):37489-94.
    View in: PubMed
    Score: 0.064
  5. Finlayson CA, Chappell J, Leitner JW, Goalstone ML, Garrity M, Nawaz S, Ciaraldi TP, Draznin B. Enhanced insulin signaling via Shc in human breast cancer. Metabolism. 2003 Dec; 52(12):1606-11.
    View in: PubMed
    Score: 0.057
  6. Barbour LA, Shao J, Qiao L, Leitner W, Anderson M, Friedman JE, Draznin B. Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle. Endocrinology. 2004 Mar; 145(3):1144-50.
    View in: PubMed
    Score: 0.057
  7. Goalstone ML, Leitner JW, Berhanu P, Sharma PM, Olefsky JM, Draznin B. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling. J Biol Chem. 2001 Apr 20; 276(16):12805-12.
    View in: PubMed
    Score: 0.047
  8. Draznin B, Miles P, Kruszynska Y, Olefsky J, Friedman J, Golovchenko I, Stjernholm R, Wall K, Reitman M, Accili D, Cooksey R, McClain D, Goalstone M. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology. 2000 Apr; 141(4):1310-6.
    View in: PubMed
    Score: 0.044
  9. Draznin B. Insulin signaling network -- waiting for Copernicus. Endocrinology. 1996 Jul; 137(7):2647-8.
    View in: PubMed
    Score: 0.034
  10. Low Wang CC, Lu L, Leitner JW, Sarraf M, Gianani R, Draznin B, Greyson CR, Reusch JE, Schwartz GG. Arterial insulin resistance in Yucatan micropigs with diet-induced obesity and metabolic syndrome. J Diabetes Complications. 2013 Jul-Aug; 27(4):307-15.
    View in: PubMed
    Score: 0.027
  11. Wang CC, Adochio RL, Leitner JW, Abeyta IM, Draznin B, Cornier MA. Acute effects of different diet compositions on skeletal muscle insulin signalling in obese individuals during caloric restriction. Metabolism. 2013 Apr; 62(4):595-603.
    View in: PubMed
    Score: 0.026
  12. Lee J, Xu Y, Lu L, Bergman B, Leitner JW, Greyson C, Draznin B, Schwartz GG. Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesity. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H310-9.
    View in: PubMed
    Score: 0.021
  13. del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO. Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes. 2007 Jun; 56(6):1638-46.
    View in: PubMed
    Score: 0.018
  14. Shao J, Yamashita H, Qiao L, Draznin B, Friedman JE. Phosphatidylinositol 3-kinase redistribution is associated with skeletal muscle insulin resistance in gestational diabetes mellitus. Diabetes. 2002 Jan; 51(1):19-29.
    View in: PubMed
    Score: 0.012
  15. Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olefsky JM. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. J Biol Chem. 1994 Apr 08; 269(14):10734-8.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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